Chunyu Liu | Profiles RNS

Chunyu Liu, PhD

Professor

Boston University School of Public Health

Biostatistics

PhD, Boston University
PhD, University of Maine
MA, Boston University

Websites

	SPH
	Google Scholar

ORCID : 0000-0002-9160-0153

Dr. Chunyu Liu earned her PhD in Biostatistics with a specialization in statistical genetics from the Department of Biostatistics at Boston University. She embarked on her professional journey at Biogen Idec Inc. in Cambridge, Massachusetts, where she served as a statistical geneticist. Additionally, she made significant contributions to the Population Sciences Branch & Framingham Heart Study (FHS), NHLBI, located in Framingham, Massachusetts.
Throughout her career, Dr. Liu has been actively engaged in diverse projects assessing risk factors associated with cardiovascular disease (CVD) and Alzheimer’s disease (AD). Her notable portfolio includes leadership roles as the Principal Investigator (PI) for three R01 grants and an R21 grant since 2018. Moreover, she serves as a subcontract PI for two R21 grants and has secured funding from the Cure Alzheimer’s Fund. In collaborative endeavors, she plays a pivotal role as the lead biostatistician in several R01 grants, contributing to over 135 peer-reviewed manuscripts. Dr. Liu often holds significant authorship positions in these publications, including as the first, second, or last author in more than 40 papers.
Dr. Liu's contributions span significant collaborative research endeavors, where she has held key roles as the lead statistician and co-convener in multiple working groups within the Cohorts for Heart and Aging Research in Genetic Epidemiology (CHARGE). Currently, she serves as a co-convener of the Trans-Omics for Precision Medicine (TOPMed) Mitochondrial DNA (mtDNA) working group, leading efforts to develop analytical methods for mtDNA sequence variations.
Furthermore, Dr. Liu shares her expertise as a member of the NIH’s Genetics of Health and Disease Study Section within the Center for Scientific Review. Her commitment extends to editorial responsibilities, acting as an Associate Editor for the Cardiovascular Digital Health Journal and an Academic Editor for PLOS ONE. Additionally, she plays an active role in the International Genetic Epidemiology Society, co-chairing its Education Committee.

Investigator
Framingham Heart Study

Member
Boston University
Evans Center for Interdisciplinary Biomedical Research

BU Research
NIH RePORTER Research

Life's Essential 8, Digital Cognitive Markers, and Alzheimer's Disease Risk
05/15/2025 - 01/31/2030 (PI)
NIH/National Institute on Aging
1R01AG086303-01A1

Calorie Restriction, Mitochondrial DNA Heteroplasmy, Cardiometabolic Profiles, and Biological Aging
08/01/2024 - 07/31/2026 (Subcontract PI)
Trustees of Tufts College NIH NIA
1R21AG085086-01

Mitochondrial DNA, Nuclear DNA Methylation, and Cardiometabolic Disease Traits
09/01/2021 - 06/30/2026 (PI)
NIH/National Heart, Lung, and Blood Institute
5R01HL155569-04

Trans-omic Analysis of Alcohol Consumption and Its Relation to Cardiovascular Disease
07/01/2021 - 04/30/2026 (PI)
NIH/National Institute on Alcohol Abuse and Alcoholism
5R01AA028263-05

Plasma proteins, sex and Alzheimer's disease: Proteome-wide analyses of the UK Biobank and Framingham Heart Study
01/22/2025 - 01/21/2026 (Subcontract PI)
Duke University Cure Alzheimers Fund

Sex Differences in Alzheimer's Disease Progression: Framingham Heart Study
10/15/2022 - 11/14/2024 (Subcontract PI)
Duke University Cure Alzheimers Fund

Mitochondrial DNA Copy number and Sequence Variation in Relation to Age, Metabolic traits, and Alzheimer's Disease Related Phenotypes
09/15/2018 - 05/31/2024 (Multi-PI)
PI: Chunyu Liu, PhD
NIH/National Institute on Aging
5R01AG059727-04

Validation of the DCTclock drawing task as a cognitive screening tool for prodromal Alzheimers disease in the Framingham Heart Study
09/30/2021 - 05/31/2023 (Subcontract PI)
Brown University NIH NIA
1R21AG072588-02

Sex Differences in Alzheimer's Disease Progression: Framingham Heart Study
02/15/2021 - 02/14/2023 (Subcontract PI)
Duke University Cure Alzheimers Fund

Mitochondrial heteroplasmy as an endophenotype of HIV-associated neurocognitive disorders
07/23/2019 - 11/30/2022 (Subcontract PI)
Cleveland Clinic Lerner College of Medicine/CWRU NIH NIMH
5R21MH121165-02

Showing 10 of 11 results. Show All Results

Title

Yr	Title	Project-Sub Proj
2026	Life's Essential 8, Digital Cognitive Markers, and Alzheimer's Disease Risk	5R01AG086303-02
2025	Life's Essential 8, Digital Cognitive Markers, and Alzheimer's Disease Risk	1R01AG086303-01A1
2025	Trans-omic Analysis of Alcohol Consumption and its Relation to Cardiovascular Disease	5R01AA028263-05
2024	Mitochondrial DNA, Nuclear DNA Methylation, and Cardiometabolic Disease Traits	5R01HL155569-04
2024	Trans-omic Analysis of Alcohol Consumption and its Relation to Cardiovascular Disease	5R01AA028263-04
2023	Mitochondrial DNA, Nuclear DNA Methylation, and Cardiometabolic Disease Traits	5R01HL155569-03
2023	Trans-omic Analysis of Alcohol Consumption and its Relation to Cardiovascular Disease	5R01AA028263-03
2022	Mitochondrial DNA, Nuclear DNA Methylation, and Cardiometabolic Disease Traits	5R01HL155569-02
2022	Trans-omic Analysis of Alcohol Consumption and its Relation to Cardiovascular Disease	5R01AA028263-02
2021	Mitochondrial DNA, Nuclear DNA Methylation, and Cardiometabolic Disease Traits	1R01HL155569-01A1

Showing 10 of 17 results. Show All Results

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis Copy PMIDs To Clipboard

Sun X, Liu X, Bulekova K, Pitsillides AN, Guo X, Yong Q, Raffield LM, Rotter JI, Rich SS, Abecasis G, Carson AP, Vasan RS, Bis JC, Psaty BM, Boerwinkle E, Fitzpatrick AL, Satizabal CL, Arking DE, Ding J, Levy D, Liu C. ASSOCIATION ANALYSIS OF MITOCHONDRIAL HETEROPLASMIC VARIANTS AND CARDIOMETABOLIC TRAITS. medRxiv. 2026 Jan 25.View Related Profiles.

Liu, Chunyu
Satizabal, Claudia
Levy, Daniel
Bulekova, Katia

PMID: 41659078; PMCID: PMC12879650; DOI: 10.64898/2026.01.23.26344724;

Zhang Y, Joehanes R, Huan T, Weber LM, Yang Q, Lunetta KL, Levy D, Liu C. Integration of latent factor analysis into multivariable Mendelian randomization. Eur J Epidemiol. 2026 Jan 12.View Related Profiles.

Liu, Chunyu
Levy, Daniel
Lunetta, Kathryn
Weber, Lukas
Yang, Qiong

PMID: 41524881; DOI: 10.1007/s10654-025-01324-8;

Ni Y, Balakumar P, Islam T, Haque SE, Shahriar MH, Sarwar G, Ahmed A, Liu C, Pierce BL, Sargis RM, Jackson B, Jasmine F, Kibriya MG, Ahsan H, Argos M. Cross-sectional association of arsenic exposure with thyroid function in Bangladeshi children aged 5 to 7 years. Environ Health. 2026 Jan 07; 25(1):9.View Related Profiles.

Liu, Chunyu
Argos, Maria

PMID: 41501906; PMCID: PMC12870816; DOI: 10.1186/s12940-025-01261-9;

Paul TJ, Sadaniantz K, Soni A, Asaker JC, Pathiravasan CH, Mehawej J, Filippaios A, Zhang Y, Wang Z, Liu C, Lin H, Murabito JM, McManus DD, Kovell LC. Patterns of adherence to home blood pressure monitoring among men and women in the Electronic Framingham Heart Study. PLoS One. 2025; 20(12):e0337284.View Related Profiles.

Liu, Chunyu
Lin, Honghuang

PMID: 41406142; PMCID: PMC12711059; DOI: 10.1371/journal.pone.0337284;

Lai M, Kim K, Zheng Y, Castellani CA, Ratliff SM, Wang M, Liu X, Haessler J, Huan T, Bonsu K, Newcomb C, McKessy K, Bielak LF, Zhao W, Joehanes R, Ma J, Guo X, Manson JE, Grove ML, Bressler J, Taylor KD, Lappalainen T, Kasela S, Blackwell TW, Lake NJ, Faul JD, Ferrier KR, Ekker SC, Hou L, Kooperberg C, Reiner AP, Zhang K, Peyser PA, Fornage M, Boerwinkle E, Raffield LM, Carson AP, Rich SS, Liu Y, Levy D, Rotter JI, Smith JA, Arking DE, Liu C. Epigenome-wide association study of nuclear DNA methylation in relation to mitochondrial heteroplasmy. Nat Commun. 2025 Dec 02; 16(1):10962. PMID: 41330919; PMCID: PMC12689632; DOI: 10.1038/s41467-025-65845-2;

Lee S, Joehanes R, Huan T, Liu C, Levy D, Ma J. Proteomics networks linking diet to cardiometabolic risk factors: the Framingham Heart Study. Am J Clin Nutr. 2026 Feb; 123(2):101131. PMID: 41338326; PMCID: PMC12743626; DOI: 10.1016/j.ajcnut.2025.101131;

Liu C, Joehanes R, Ma J, Xie J, Yang J, Wang M, Huan T, Hwang SJ, Wen J, Sun Q, Demirkale CY, Heard-Costa NL, Orchard P, Carson AP, Haessler JW, Raffield LM, Reiner AP, Franceschini N, Auer PL, Kooperberg C, Li Y, O'Connor G, Murabito JM, Munson P, Levy D. Integrating whole genome and transcriptome sequencing to characterize the genetic architecture of isoform variation. Nat Commun. 2025 Nov 22; 16(1):10615. PMID: 41274869; PMCID: PMC12660940; DOI: 10.1038/s41467-025-64336-8;

Wang M, Zheng Y, Lai M, Saake E, Liu X, Guo X, Taylor KD, Huan T, Joehanes R, Nannini DR, Zhang K, Lake NJ, Castellani CA, Rich SS, Rotter JI, Liu Y, Raffield LM, Carson AP, Fornage M, Ma J, Arking DE, Hou L, Levy D, Liu C. Association of Epigenetic Age Acceleration and Mitochondrial DNA-Based Aging Metrics Provides Insights Into Mechanisms of Aging-Related Diseases. Aging Cell. 2025 Dec; 24(12):e70279. PMID: 41132105; PMCID: PMC12686565; DOI: 10.1111/acel.70279;

Zhang Y, Rong J, Wang X, Schramm E, Pathiravasan CH, Borrelli B, Faro JM, Benjamin EJ, Trinquart L, Liu C, Murabito JM. Smartphone App-Based Survey Deployment Patterns and Longitudinal Response Rate: Randomized Controlled Trial. J Med Internet Res. 2025 Oct 10; 27:e73972.View Related Profiles.

Liu, Chunyu
Benjamin, Emelia
Murabito, Joanne

PMID: 41071587; PMCID: PMC12552817; DOI: 10.2196/73972;

Rotti L, Murabito JM, Chen J, Cao Y, Ragab AAY, Liu C, Wang M, Doyle MF, Lunetta KL. Immune cells and inflammatory proteins are differentially associated with subsequent DNA methylation biological aging measures in the Framingham Heart Study Offspring Cohort. Geroscience. 2025 Oct 02.View Related Profiles.

Liu, Chunyu
Murabito, Joanne
Lunetta, Kathryn

PMID: 41039184; DOI: 10.1007/s11357-025-01883-4;

Showing 10 of 186 results. Show More

Li Z, Ding H, Wang M, Li Y, Ang TFA, Ashita G, Gifford KA, Karjadi C, Levy D, Au R, Liu C. Association of DNA methylation age acceleration with digital clock drawing test performance: the Framingham Heart Study. Aging (Albany NY). 2025 Jul 21; 17(7):1721-1745.View Related Profiles.

Gurnani, Ashita
Liu, Chunyu
Ding, Huitong
Gifford, Katherine
Au, Rhoda
Ang, Ting Fang Alvin

PMID: 40699219; PMCID: PMC12339028; DOI: 10.18632/aging.206285;

Carbonneau M, Li Y, Qu Y, Zheng Y, Wood AC, Wang M, Liu C, Huan T, Joehanes R, Guo X, Yao J, Taylor KD, Tracy RP, Durda P, Liu Y, Johnson WC, Post WS, Blackwell T, Rotter JI, Rich SS, Redline S, Fornage M, Wang J, Ning H, Hou L, Lloyd-Jones D, Ferrier K, Min YI, Carson AP, Raffield LM, Teumer A, Grabe HJ, Völzke H, Nauck M, Dörr M, Domingo-Relloso A, Fretts A, Tellez-Plaza M, Cole SA, Navas-Acien A, Wang M, Murabito JM, Heard-Costa NL, Prescott B, Xanthakis V, Mozaffarian D, Levy D, Ma J. DNA Methylation Signatures of Cardiovascular Health Provide Insights Into Diseases. Circulation. 2025 Aug 19; 152(7):436-449.View Related Profiles.

Liu, Chunyu
Lloyd-Jones, Donald
Murabito, Joanne
Heard-Costa, Nancy
Xanthakis, Vanessa

PMID: 40654086; PMCID: PMC12262172; DOI: 10.1161/CIRCULATIONAHA.124.073181;

Wang X, Zhang Y, Pathiravasan CH, Spartano NL, Benjamin EJ, McManus DD, Lewis GD, Larson MG, Vasan RS, Murabito JM, Liu C, Nayor M. Blood Pressure Responses During Exercise Were Associated With Average Home Blood Pressure and Home Blood Pressure Variability: The Electronic Framingham Heart Study. J Am Heart Assoc. 2025 Jun 03; 14(11):e039457.View Related Profiles.

Pathiravasan, Chathurangi
Liu, Chunyu
Benjamin, Emelia
Murabito, Joanne
Nayor, Matthew
Spartano, Nicole

PMID: 40459124; PMCID: PMC12229214; DOI: 10.1161/JAHA.124.039457;

Lundin JI, Peters U, Hu Y, Ammous F, Benjamin EJ, Bis JC, Brody JA, Cushman M, Fuller H, Gignoux C, Guo X, Haessler J, Haiman C, Joehanes R, Kasela S, Kenny E, Lappalainen T, Levy D, Liu C, Liu Y, Loos RJF, Matise T, North KE, Park SL, Ratliff SM, Reiner A, Rich SS, Rotter JI, Smith JA, Sotoodehnia N, Tracy R, Van den Berg D, Ye T, Zhao W, Raffield LM, Kooperberg C. Epigenetic mechanisms underlying variation of IL-6, a well-established inflammation biomarker and risk factor for cardiovascular disease. Atherosclerosis. 2025 Aug; 407:120219.View Related Profiles.

Liu, Chunyu
Benjamin, Emelia

PMID: 40480020; PMCID: PMC12276907; DOI: 10.1016/j.atherosclerosis.2025.120219;

Wang X, Larson MG, Liu C. Two-stage multiple imputation with a longitudinal composite variable. BMC Med Res Methodol. 2025 May 06; 25(1):124. PMID: 40329169; PMCID: PMC12054270; DOI: 10.1186/s12874-025-02555-9;

Ambrosone CB, Yao S, Long MD, Liu C, Chen J, Davis W, Zirpoli G, Payne-Ondracek R, Khoury T, Gong Z, Hu Q, Szewczyk S, Omilian AR, Bandera EV, Liu S, Kushi L, Higgins MJ, Palmer JR. Associations of DNA methylation in breast tumour subtypes with parity and breastfeeding in a cohort of 1459 Black women: implications for public health. BMJ Oncol. 2025; 4(1):e000675.View Related Profiles.

Liu, Chunyu
Zirpoli, Gary
Palmer, Julie

PMID: 40519219; PMCID: PMC12164313; DOI: 10.1136/bmjonc-2024-000675;

Yang J, Ding H, Li Y, Ang TFA, Devine S, Liu Y, Qiu W, Au R, Ma J, Liu C. Association of mid-age Life's Essential 8 score with digital cognitive performance and incident Alzheimer's disease: The Framingham Heart Study. J Alzheimers Dis. 2025 Mar; 104(2):498-508.View Related Profiles.

Liu, Chunyu
Ding, Huitong
Au, Rhoda
Devine, Sherral
Ang, Ting Fang Alvin
Qiu, Wendy

PMID: 40025717; DOI: 10.1177/13872877251317734;

Zhao D, Yao J, Li Y, Jacobs DR, Zheng Y, Liu C, Fu Y, Deangelis MM, Lloyd-Jones D, Hou L, Zhang K. Associations of long-term exposure to temperature with coronary artery calcification risk among middle-aged adults: The Coronary Artery Risk Development in Young Adults (CARDIA) study. Sci Total Environ. 2025 Feb 25; 966:178675.View Related Profiles.

Liu, Chunyu
Lloyd-Jones, Donald

PMID: 39904207; PMCID: PMC12356213; DOI: 10.1016/j.scitotenv.2025.178675;

Li J, Liu C, Ang TFA, Au R. Associations of Mid- and Late-Life Fasting Blood Glucose Levels With Dementia Risk Among Patients With Diabetes: Framingham Heart Study. Eur J Neurol. 2025 Feb; 32(2):e70062.View Related Profiles.

Liu, Chunyu
Au, Rhoda
Ang, Ting Fang Alvin

PMID: 39910859; PMCID: PMC11799049; DOI: 10.1111/ene.70062;

Sheehy S, Friedman D, Liu C, Lunetta KL, Zirpoli G, Palmer JR. Association between Apolipoprotein L1 genetic variants and risk of preeclampsia and preterm birth among U.S. Black women. Eur J Obstet Gynecol Reprod Biol X. 2025 Mar; 25:100365.View Related Profiles.

Liu, Chunyu
Zirpoli, Gary
Palmer, Julie
Lunetta, Kathryn

PMID: 39895997; PMCID: PMC11783058; DOI: 10.1016/j.eurox.2025.100365;

Leng Y, Ding H, Ang TFA, Au R, Doraiswamy PM, Liu C. Identifying proteomic prognostic markers for Alzheimer's disease with survival machine learning: The Framingham Heart Study. J Prev Alzheimers Dis. 2025 Feb; 12(2):100021.View Related Profiles.

Liu, Chunyu
Ding, Huitong
Au, Rhoda
Ang, Ting Fang Alvin

PMID: 39863332; PMCID: PMC12184055; DOI: 10.1016/j.tjpad.2024.100021;

Rong J, Pathiravasan CH, Zhang Y, Faro JM, Wang X, Schramm E, Borrelli B, Benjamin EJ, Liu C, Murabito JM. Baseline Smartphone App Survey Return in the Electronic Framingham Heart Study Offspring and Omni 1 Study: eCohort Study. JMIR Aging. 2024 Dec 31; 7:e64636.View Related Profiles.

Borrelli, Belinda
Pathiravasan, Chathurangi
Liu, Chunyu
Benjamin, Emelia
Rong, Jian
Murabito, Joanne

PMID: 39740111; PMCID: PMC11706443; DOI: 10.2196/64636;

O'Shea S, Liu Y, Liu C, Frank SA, Shih LC, Au R. Obesity and the development of Parkinson's disease within the Framingham Heart study cohort. Clin Park Relat Disord. 2025; 12:100291.View Related Profiles.

Liu, Chunyu
Au, Rhoda
O'Shea, Sarah

PMID: 39758706; PMCID: PMC11700282; DOI: 10.1016/j.prdoa.2024.100291;

Carbonneau M, Li Y, Qu Y, Zheng Y, Wood AC, Wang M, Liu C, Huan T, Joehanes R, Guo X, Yao J, Taylor KD, Tracy RP, Peter D, Liu Y, Johnson WC, Post WS, Blackwell T, Rotter JI, Rich SS, Redline S, Fornage M, Wang J, Ning H, Hou L, Lloyd-Jones D, Ferrier K, Min YI, Carson AP, Raffield LM, Teumer A, Grabe HJ, Völzke H, Nauck M, Dörr M, Domingo-Relloso A, Fretts A, Tellez-Plaza M, Cole S, Navas-Acien A, Wang M, Murabito JM, Heard-Costa NL, Prescott B, Xanthakis V, Mozaffarian D, Levy D, Ma J. DNA Methylation Signatures of Cardiovascular Health Provide Insights into Diseases. medRxiv. 2024 Nov 20.View Related Profiles.

Liu, Chunyu
Lloyd-Jones, Donald
Murabito, Joanne
Heard-Costa, Nancy
Xanthakis, Vanessa

PMID: 39606375; PMCID: PMC11601778; DOI: 10.1101/2024.11.19.24317587;

Bui H, Keshawarz A, Wang M, Lee M, Ratliff SM, Lin L, Birditt KS, Faul JD, Peters A, Gieger C, Delerue T, Kardia SLR, Zhao W, Guo X, Yao J, Rotter JI, Li Y, Liu X, Liu D, Tavares JF, Pehlivan G, Breteler MMB, Karabegovic I, Ochoa-Rosales C, Voortman T, Ghanbari M, van Meurs JBJ, Nasr MK, Dörr M, Grabe HJ, London SJ, Teumer A, Waldenberger M, Weir DR, Smith JA, Levy D, Ma J, Liu C. Association analysis between an epigenetic alcohol risk score and blood pressure. Clin Epigenetics. 2024 Oct 28; 16(1):149. PMID: 39468603; PMCID: PMC11520477; DOI: 10.1186/s13148-024-01753-4;

Yuan J, Tao Q, Ang TFA, Liu C, Devine S, Auerbach SH, Mez J, Farrer LA, Qiu WQ, Au R. The Relationship between Framingham Stroke Risk Profile on Incident Dementia and Alzheimer's Disease: A 40-Year Follow-Up Study Highlighting Female Vulnerability. Ann Neurol. 2024 Dec; 96(6):1124-1134.View Related Profiles.

Liu, Chunyu
Mez, Jesse
Farrer, Lindsay
Tao, Qiushan
Au, Rhoda
Auerbach, Sanford
Devine, Sherral
Ang, Ting Fang Alvin
Qiu, Wendy

PMID: 39404028

Leng Y, Ding H, Alvin Ang TF, Au R, Doraiswamy PM, Liu C. Identifying Proteomic Prognostic Markers for Alzheimer's Disease with Survival Machine Learning: the Framingham Heart Study. medRxiv. 2024 Sep 23.View Related Profiles.

Liu, Chunyu
Ding, Huitong
Au, Rhoda

PMID: 39399041; PMCID: PMC11469405; DOI: 10.1101/2024.09.21.24314123;

Sun X, Bulekova K, Yang J, Lai M, Pitsillides AN, Liu X, Zhang Y, Guo X, Yong Q, Raffield LM, Rotter JI, Rich SS, Abecasis G, Carson AP, Vasan RS, Bis JC, Psaty BM, Boerwinkle E, Fitzpatrick AL, Satizabal CL, Arking DE, Ding J, Levy D, Liu C. Association analysis of mitochondrial DNA heteroplasmic variants: Methods and application. Mitochondrion. 2024 Nov; 79:101954.View Related Profiles.

Liu, Chunyu
Satizabal, Claudia
Levy, Daniel
Bulekova, Katia

PMID: 39245194; PMCID: PMC11568909; DOI: 10.1016/j.mito.2024.101954;

Xu W, Hong YS, Hu B, Comhair SAA, Janocha AJ, Zein JG, Chen R, Meyers DA, Mauger DT, Ortega VE, Bleecker ER, Castro M, Denlinger LC, Fahy JV, Israel E, Levy BD, Jarjour NN, Moore WC, Wenzel SE, Gaston B, Liu C, Arking DE, Erzurum SC. Mitochondrial DNA copy number variation in asthma risk, severity, and exacerbations. J Allergy Clin Immunol. 2025 Apr; 155(4):1224-1235. PMID: 39237012; PMCID: PMC11875079; DOI: 10.1016/j.jaci.2024.08.022;

Spartano NL, Zhang Y, Liu C, Chernofsky A, Lin H, Trinquart L, Borrelli B, Pathiravasan CH, Kheterpal V, Nowak C, Vasan RS, Benjamin EJ, McManus DD, Murabito JM. Agreement Between Apple Watch and Actical Step Counts in a Community Setting: Cross-Sectional Investigation From the Framingham Heart Study. JMIR Biomed Eng. 2024 Jul 24; 9:e54631.View Related Profiles.

Borrelli, Belinda
Pathiravasan, Chathurangi
Liu, Chunyu
Benjamin, Emelia
Lin, Honghuang
Murabito, Joanne
Trinquart, Ludovic
Spartano, Nicole

PMID: 39047284; PMCID: PMC11306942; DOI: 10.2196/54631;

Zhang Y, Wang X, Pathiravasan CH, Spartano NL, Lin H, Borrelli B, Benjamin EJ, McManus DD, Larson MG, Vasan RS, Shah RV, Lewis GD, Liu C, Murabito JM, Nayor M. Association of Smartwatch-Based Heart Rate and Physical Activity With Cardiorespiratory Fitness Measures in the Community: Cohort Study. J Med Internet Res. 2024 Jun 13; 26:e56676.View Related Profiles.

Borrelli, Belinda
Pathiravasan, Chathurangi
Liu, Chunyu
Benjamin, Emelia
Lin, Honghuang
Murabito, Joanne
Larson, Martin
Nayor, Matthew
Spartano, Nicole

PMID: 38870519; PMCID: PMC11216017; DOI: 10.2196/56676;

Carbonneau M, Li Y, Prescott B, Liu C, Huan T, Joehanes R, Murabito JM, Heard-Costa NL, Xanthakis V, Levy D, Ma J. Epigenetic Age Mediates the Association of Life's Essential 8 With Cardiovascular Disease and Mortality. J Am Heart Assoc. 2024 Jun 04; 13(11):e032743.View Related Profiles.

Liu, Chunyu
Murabito, Joanne
Heard-Costa, Nancy
Xanthakis, Vanessa

PMID: 38808571; PMCID: PMC11255626; DOI: 10.1161/JAHA.123.032743;

Lyu C, Joehanes R, Huan T, Levy D, Li Y, Wang M, Liu X, Liu C, Ma J. Enhancing selection of alcohol consumption-associated genes by random forest. Br J Nutr. 2024 Jun 28; 131(12):2058-2067.View Related Profiles.

Liu, Chunyu
Levy, Daniel

PMID: 38606596; PMCID: PMC11216877; DOI: 10.1017/S0007114524000795;

Wang X, Zhang Y, Pathiravasan CH, Ukonu NC, Rong J, Benjamin EJ, McManus DD, Larson MG, Vasan RS, Hamburg NM, Murabito JM, Liu C, Mitchell GF. Association of Arterial Stiffness With Mid- to Long-Term Home Blood Pressure Variability in the Electronic Framingham Heart Study: Cohort Study. JMIR Cardio. 2024 Apr 08; 8:e54801.View Related Profiles.

Pathiravasan, Chathurangi
Liu, Chunyu
Benjamin, Emelia
Rong, Jian
Murabito, Joanne
Larson, Martin
Hamburg, Naomi

PMID: 38587880; PMCID: PMC11036191; DOI: 10.2196/54801;

Lundin JI, Peters U, Hu Y, Ammous F, Avery CL, Benjamin EJ, Bis JC, Brody JA, Carlson C, Cushman M, Gignoux C, Guo X, Haessler J, Haiman C, Joehanes R, Kasela S, Kenny E, Lapalainien T, Levy D, Liu C, Liu Y, Loos RJF, Lu A, Matise T, North KE, Park SL, Ratliff SM, Reiner A, Rich SS, Rotter JI, Smith JA, Sotoodehnia N, Tracy R, Van den Berg D, Xu H, Ye T, Zhao W, Raffield LM, Kooperberg C. Methylation patterns associated with C-reactive protein in racially and ethnically diverse populations. Epigenetics. 2024 Dec; 19(1):2333668.View Related Profiles.

Liu, Chunyu
Benjamin, Emelia

PMID: 38571307; PMCID: PMC10996836; DOI: 10.1080/15592294.2024.2333668;

Ding H, Liu C, Li Y, Ang TFA, Devine S, Liu Y, Au R, Doraiswamy PM. Sex-specific blood biomarkers linked to memory changes in middle-aged adults: The Framingham Heart Study. Alzheimers Dement (Amst). 2024; 16(1):e12569.View Related Profiles.

Liu, Chunyu
Ding, Huitong
Au, Rhoda
Devine, Sherral
Ang, Ting Fang Alvin

PMID: 38545543; PMCID: PMC10966919; DOI: 10.1002/dad2.12569;

Lee J, Wang X, Liu C, Pathiravasan CH, Benjamin EJ, McManus DD, Murabito JM. Depressive symptoms are not associated with clinically important levels of digital home blood pressure in the electronic Framingham Heart Study. Cardiovasc Digit Health J. 2024 Apr; 5(2):50-58.View Related Profiles.

Pathiravasan, Chathurangi
Liu, Chunyu
Benjamin, Emelia
Murabito, Joanne

PMID: 38765623; PMCID: PMC11096660; DOI: 10.1016/j.cvdhj.2024.01.001;

Sun X, Bulekova K, Yang J, Lai M, Pitsillides AN, Liu X, Zhang Y, Guo X, Yong Q, Raffield LM, Rotter JI, Rich SS, Abecasis G, Carson AP, Vasan RS, Bis JC, Psaty BM, Boerwinkle E, Fitzpatrick AL, Satizabal CL, Arking DE, Ding J, Levy D, Liu C. Association analysis of mitochondrial DNA heteroplasmic variants: methods and application. medRxiv. 2024 Jan 13.View Related Profiles.

Liu, Chunyu
Satizabal, Claudia
Bulekova, Katia

PMID: 38260412; PMCID: PMC10802757; DOI: 10.1101/2024.01.12.24301233;

Kim SJ, Miller B, Hartel NG, Ramirez R, Braniff RG, Leelaprachakul N, Huang A, Wang Y, Arpawong TE, Crimmins EM, Wang P, Sun X, Liu C, Levy D, Yen K, Petzinger GM, Graham NA, Jakowec MW, Cohen P. A naturally occurring variant of SHLP2 is a protective factor in Parkinson's disease. Mol Psychiatry. 2024 Feb; 29(2):505-517. PMID: 38167865; PMCID: PMC11116102; DOI: 10.1038/s41380-023-02344-0;

Xu W, Hong YS, Hu B, Comhair SAA, Janocha AJ, Zein JG, Chen R, Meyers DA, Mauger DT, Ortega VE, Bleecker ER, Castro M, Denlinger LC, Fahy JV, Israel E, Levy BD, Jarjour NN, Moore WC, Wenzel SE, Gaston B, Liu C, Arking DE, Erzurum SC. Mitochondrial DNA Copy Number Variation in Asthma Risk, Severity, and Exacerbations. medRxiv. 2023 Dec 05. PMID: 38106101; PMCID: PMC10723502; DOI: 10.1101/2023.12.05.23299392;

Li Y, Wang M, Liu X, Rong J, Miller PE, Joehanes R, Huan T, Guo X, Rotter JI, Smith JA, Yu B, Nayor M, Levy D, Liu C, Ma J. Circulating metabolites may illustrate relationship of alcohol consumption with cardiovascular disease. BMC Med. 2023 Nov 16; 21(1):443.View Related Profiles.

Liu, Chunyu
Nayor, Matthew

PMID: 37968697; PMCID: PMC10652547; DOI: 10.1186/s12916-023-03149-2;

Sarnowski C, Huan T, Ma Y, Joehanes R, Beiser A, DeCarli CS, Heard-Costa NL, Levy D, Lin H, Liu CT, Liu C, Meigs JB, Satizabal CL, Florez JC, Hivert MF, Dupuis J, De Jager PL, Bennett DA, Seshadri S, Morrison AC. Multi-tissue epigenetic analysis identifies distinct associations underlying insulin resistance and Alzheimer's disease at CPT1A locus. Clin Epigenetics. 2023 Oct 27; 15(1):173.View Related Profiles.

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PMID: 37891690; PMCID: PMC10612362; DOI: 10.1186/s13148-023-01589-4;

Ferretti MT, Ding H, Au R, Liu C, Devine S, Auerbach S, Mez J, Gurnani A, Liu Y, Santuccione A, Ang TFA. Maximizing utility of neuropsychological measures in sex-specific predictive models of incident Alzheimer's disease in the Framingham Heart Study. Alzheimers Dement. 2024 Feb; 20(2):1112-1122.View Related Profiles.

Gurnani, Ashita
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Ding, Huitong
Mez, Jesse
Au, Rhoda
Auerbach, Sanford
Devine, Sherral
Ang, Ting Fang Alvin

PMID: 37882354; PMCID: PMC10917035; DOI: 10.1002/alz.13500;

Wang M, Li Y, Lai M, Nannini DR, Hou L, Joehanes R, Huan T, Levy D, Ma J, Liu C. Alcohol consumption and epigenetic age acceleration across human adulthood. Aging (Albany NY). 2023 Oct 26; 15(20):10938-10971.View Related Profiles.

Liu, Chunyu
Levy, Daniel

PMID: 37889500; PMCID: PMC10637803; DOI: 10.18632/aging.205153;

Liu X, Sun X, Zhang Y, Jiang W, Lai M, Wiggins KL, Raffield LM, Bielak LF, Zhao W, Pitsillides A, Haessler J, Zheng Y, Blackwell TW, Yao J, Guo X, Qian Y, Thyagarajan B, Pankratz N, Rich SS, Taylor KD, Peyser PA, Heckbert SR, Seshadri S, Boerwinkle E, Grove ML, Larson NB, Smith JA, Vasan RS, Fitzpatrick AL, Fornage M, Ding J, Carson AP, Abecasis G, Dupuis J, Reiner A, Kooperberg C, Hou L, Psaty BM, Wilson JG, Levy D, Rotter JI, Bis JC, Satizabal CL, Arking DE, Liu C. Association Between Whole Blood-Derived Mitochondrial DNA Copy Number, Low-Density Lipoprotein Cholesterol, and Cardiovascular Disease Risk. J Am Heart Assoc. 2023 Oct 17; 12(20):e029090.View Related Profiles.

Liu, Chunyu
Satizabal, Claudia
Dupuis, Josee
Seshadri, Sudha

PMID: 37804200; PMCID: PMC10757530; DOI: 10.1161/JAHA.122.029090;

Wang Y, Selvaraj MS, Li X, Li Z, Holdcraft JA, Arnett DK, Bis JC, Blangero J, Boerwinkle E, Bowden DW, Cade BE, Carlson JC, Carson AP, Chen YI, Curran JE, de Vries PS, Dutcher SK, Ellinor PT, Floyd JS, Fornage M, Freedman BI, Gabriel S, Germer S, Gibbs RA, Guo X, He J, Heard-Costa N, Hildalgo B, Hou L, Irvin MR, Joehanes R, Kaplan RC, Kardia SL, Kelly TN, Kim R, Kooperberg C, Kral BG, Levy D, Li C, Liu C, Lloyd-Jone D, Loos RJ, Mahaney MC, Martin LW, Mathias RA, Minster RL, Mitchell BD, Montasser ME, Morrison AC, Murabito JM, Naseri T, O'Connell JR, Palmer ND, Preuss MH, Psaty BM, Raffield LM, Rao DC, Redline S, Reiner AP, Rich SS, Ruepena MS, Sheu WH, Smith JA, Smith A, Tiwari HK, Tsai MY, Viaud-Martinez KA, Wang Z, Yanek LR, Zhao W, Rotter JI, Lin X, Natarajan P, Peloso GM. Rare variants in long non-coding RNAs are associated with blood lipid levels in the TOPMed whole-genome sequencing study. Am J Hum Genet. 2023 Oct 05; 110(10):1704-1717.View Related Profiles.

Liu, Chunyu
Levy, Daniel
Peloso, Gina
Murabito, Joanne
Heard-Costa, Nancy
Zhao, Wei

PMID: 37802043; PMCID: PMC10577076; DOI: 10.1016/j.ajhg.2023.09.003;

Wang X, Pathiravasan CH, Zhang Y, Trinquart L, Borrelli B, Spartano NL, Lin H, Nowak C, Kheterpal V, Benjamin EJ, McManus DD, Murabito JM, Liu C. Association of Depressive Symptom Trajectory With Physical Activity Collected by mHealth Devices in the Electronic Framingham Heart Study: Cohort Study. JMIR Ment Health. 2023 Jul 14; 10:e44529.View Related Profiles.

Borrelli, Belinda
Pathiravasan, Chathurangi
Liu, Chunyu
Benjamin, Emelia
Lin, Honghuang
Murabito, Joanne
Trinquart, Ludovic
Spartano, Nicole

PMID: 37450333; PMCID: PMC10382951; DOI: 10.2196/44529;

Wang Y, Selvaraj MS, Li X, Li Z, Holdcraft JA, Arnett DK, Bis JC, Blangero J, Boerwinkle E, Bowden DW, Cade BE, Carlson JC, Carson AP, Chen YI, Curran JE, de Vries PS, Dutcher SK, Ellinor PT, Floyd JS, Fornage M, Freedman BI, Gabriel S, Germer S, Gibbs RA, Guo X, He J, Heard-Costa N, Hildalgo B, Hou L, Irvin MR, Joehanes R, Kaplan RC, Kardia SL, Kelly TN, Kim R, Kooperberg C, Kral BG, Levy D, Li C, Liu C, Lloyd-Jone D, Loos RJ, Mahaney MC, Martin LW, Mathias RA, Minster RL, Mitchell BD, Montasser ME, Morrison AC, Murabito JM, Naseri T, O'Connell JR, Palmer ND, Preuss MH, Psaty BM, Raffield LM, Rao DC, Redline S, Reiner AP, Rich SS, Ruepena MS, Sheu WH, Smith JA, Smith A, Tiwari HK, Tsai MY, Viaud-Martinez KA, Wang Z, Yanek LR, Zhao W, Rotter JI, Lin X, Natarajan P, Peloso GM. Rare variants in long non-coding RNAs are associated with blood lipid levels in the TOPMed Whole Genome Sequencing Study. medRxiv. 2023 Jun 29.View Related Profiles.

Liu, Chunyu
Levy, Daniel
Peloso, Gina
Murabito, Joanne
Heard-Costa, Nancy
Zhao, Wei

PMID: 37425772; PMCID: PMC10327287; DOI: 10.1101/2023.06.28.23291966;

Shapira-Daniels A, Kornej J, Spartano NL, Wang X, Zhang Y, Pathiravasan CH, Liu C, Trinquart L, Borrelli B, McManus DD, Murabito JM, Benjamin EJ, Lin H. Step Count, Self-reported Physical Activity, and Predicted 5-Year Risk of Atrial Fibrillation: Cross-sectional Analysis. J Med Internet Res. 2023 Mar 06; 25:e43123.View Related Profiles.

Shapira-Daniels, Ayelet
Borrelli, Belinda
Pathiravasan, Chathurangi
Liu, Chunyu
Benjamin, Emelia
Lin, Honghuang
Murabito, Joanne
Trinquart, Ludovic
Spartano, Nicole

PMID: 36877540; PMCID: PMC10028513; DOI: 10.2196/43123;

Yuan J, Liu X, Liu C, Ang AF, Massaro J, Devine SA, Auerbach SH, Blusztajn JK, Au R, Jacques PF. Is dietary choline intake related to dementia and Alzheimer's disease risks? Results from the Framingham Heart Study. Am J Clin Nutr. 2022 Nov; 116(5):1201-1207.View Related Profiles.

Liu, Chunyu
Blusztajn, Jan
Yuan, Jin
Au, Rhoda
Auerbach, Sanford
Devine, Sherral

PMID: 37208066; PMCID: PMC9630864; DOI: 10.1093/ajcn/nqac193;

Ma J, Huang A, Yan K, Li Y, Sun X, Joehanes R, Huan T, Levy D, Liu C. Blood transcriptomic biomarkers of alcohol consumption and cardiovascular disease risk factors: the Framingham Heart Study. Hum Mol Genet. 2023 Jan 27; 32(4):649-658. PMID: 36130209; PMCID: PMC9896471; DOI: 10.1093/hmg/ddac237;

Trinquart L, Liu C, McManus DD, Nowak C, Lin H, Spartano NL, Borrelli B, Benjamin EJ, Murabito JM. Increasing Engagement in the Electronic Framingham Heart Study: Factorial Randomized Controlled Trial. J Med Internet Res. 2023 Jan 20; 25:e40784.View Related Profiles.

Borrelli, Belinda
Liu, Chunyu
Benjamin, Emelia
Lin, Honghuang
Murabito, Joanne
Trinquart, Ludovic
Spartano, Nicole

PMID: 36662544; PMCID: PMC9898831; DOI: 10.2196/40784;

Hwang PH, Ang TFA, De Anda-Duran I, Liu X, Liu Y, Gurnani A, Mez J, Auerbach S, Joshi P, Yuan J, Devine S, Au R, Liu C. Examination of potentially modifiable dementia risk factors across the adult life course: The Framingham Heart Study. Alzheimers Dement. 2023 Jul; 19(7):2975-2983.View Related Profiles.

Gurnani, Ashita
Liu, Chunyu
Mez, Jesse
Yuan, Jin
Hwang, Phillip
Au, Rhoda
Auerbach, Sanford
Devine, Sherral
Ang, Ting Fang Alvin

PMID: 36656649; PMCID: PMC10354206; DOI: 10.1002/alz.12940;

Nannini DR, Joyce BT, Zheng Y, Gao T, Wang J, Liu L, Jacobs DR, Schreiner PJ, Liu C, Dai Q, Horvath S, Lu AT, Yaffe K, Greenland P, Lloyd-Jones DM, Hou L. Alcohol consumption and epigenetic age acceleration in young adults. Aging (Albany NY). 2023 Jan 05; 15(2):371-395.View Related Profiles.

Liu, Chunyu
Lloyd-Jones, Donald

PMID: 36622282; PMCID: PMC9925681; DOI: 10.18632/aging.204467;

Ding H, Li Y, Ang TFA, Liu Y, Devine S, Au R, Doraiswamy PM, Liu C. Reproductive Markers in Alzheimer's Disease Progression: The Framingham Heart Study. J Prev Alzheimers Dis. 2023; 10(3):530-535.View Related Profiles.

Liu, Chunyu
Ding, Huitong
Au, Rhoda
Devine, Sherral
Ang, Ting Fang Alvin

PMID: 37357294

Pathiravasan CH, Zhang Y, Wang X, Trinquart L, Benjamin EJ, Borrelli B, McManus DD, Kheterpal V, Lin H, Spartano NL, Schramm E, Liu C, Murabito JM. Factors associated with long-term use of digital devices in the electronic Framingham Heart Study. NPJ Digit Med. 2022 Dec 27; 5(1):195.View Related Profiles.

Borrelli, Belinda
Pathiravasan, Chathurangi
Liu, Chunyu
Benjamin, Emelia
Lin, Honghuang
Murabito, Joanne
Trinquart, Ludovic
Spartano, Nicole

PMID: 36572707; PMCID: PMC9792462; DOI: 10.1038/s41746-022-00735-1;

Li J, Liu C, Ang TFA, Au R. BMI decline patterns and relation to dementia risk across four decades of follow-up in the Framingham Study. Alzheimers Dement. 2023 Jun; 19(6):2520-2527.View Related Profiles.

Liu, Chunyu
Au, Rhoda
Ang, Ting Fang Alvin

PMID: 36519667; DOI: 10.1002/alz.12839;

Saunders GRB, Wang X, Chen F, Jang SK, Liu M, Wang C, Gao S, Jiang Y, Khunsriraksakul C, Otto JM, Addison C, Akiyama M, Albert CM, Aliev F, Alonso A, Arnett DK, Ashley-Koch AE, Ashrani AA, Barnes KC, Barr RG, Bartz TM, Becker DM, Bielak LF, Benjamin EJ, Bis JC, Bjornsdottir G, Blangero J, Bleecker ER, Boardman JD, Boerwinkle E, Boomsma DI, Boorgula MP, Bowden DW, Brody JA, Cade BE, Chasman DI, Chavan S, Chen YI, Chen Z, Cheng I, Cho MH, Choquet H, Cole JW, Cornelis MC, Cucca F, Curran JE, de Andrade M, Dick DM, Docherty AR, Duggirala R, Eaton CB, Ehringer MA, Esko T, Faul JD, Silva LF, Fiorillo E, Fornage M, Freedman BI, Gabrielsen ME, Garrett ME, Gharib SA, Gieger C, Gillespie N, Glahn DC, Gordon SD, Gu CC, Gu D, Gudbjartsson DF, Guo X, Haessler J, Hall ME, Haller T, Harris KM, He J, Herd P, Hewitt JK, Hickie I, Hidalgo B, Hokanson JE, Hopfer C, Hottenga J, Hou L, Huang H, Hung YJ, Hunter DJ, Hveem K, Hwang SJ, Hwu CM, Iacono W, Irvin MR, Jee YH, Johnson EO, Joo YY, Jorgenson E, Justice AE, Kamatani Y, Kaplan RC, Kaprio J, Kardia SLR, Keller MC, Kelly TN, Kooperberg C, Korhonen T, Kraft P, Krauter K, Kuusisto J, Laakso M, Lasky-Su J, Lee WJ, Lee JJ, Levy D, Li L, Li K, Li Y, Lin K, Lind PA, Liu C, Lloyd-Jones DM, Lutz SM, Ma J, Mägi R, Manichaikul A, Martin NG, Mathur R, Matoba N, McArdle PF, McGue M, McQueen MB, Medland SE, Metspalu A, Meyers DA, Millwood IY, Mitchell BD, Mohlke KL, Moll M, Montasser ME, Morrison AC, Mulas A, Nielsen JB, North KE, Oelsner EC, Okada Y, Orrù V, Palmer ND, Palviainen T, Pandit A, Park SL, Peters U, Peters A, Peyser PA, Polderman TJC, Rafaels N, Redline S, Reed RM, Reiner AP, Rice JP, Rich SS, Richmond NE, Roan C, Rotter JI, Rueschman MN, Runarsdottir V, Saccone NL, Schwartz DA, Shadyab AH, Shi J, Shringarpure SS, Sicinski K, Skogholt AH, Smith JA, Smith NL, Sotoodehnia N, Stallings MC, Stefansson H, Stefansson K, Stitzel JA, Sun X, Syed M, Tal-Singer R, Taylor AE, Taylor KD, Telen MJ, Thai KK, Tiwari H, Turman C, Tyrfingsson T, Wall TL, Walters RG, Weir DR, Weiss ST, White WB, Whitfield JB, Wiggins KL, Willemsen G, Willer CJ, Winsvold BS, Xu H, Yanek LR, Yin J, Young KL, Young KA, Yu B, Zhao W, Zhou W, Zöllner S, Zuccolo L, Batini C, Bergen AW, Bierut LJ, David SP, Gagliano Taliun SA, Hancock DB, Jiang B, Munafò MR, Thorgeirsson TE, Liu DJ, Vrieze S. Genetic diversity fuels gene discovery for tobacco and alcohol use. Nature. 2022 Dec; 612(7941):720-724.View Related Profiles.

Liu, Chunyu
Lloyd-Jones, Donald
Benjamin, Emelia
Hwang, Shih-Jen

PMID: 36477530; PMCID: PMC9771818; DOI: 10.1038/s41586-022-05477-4;

Liu C, Joehanes R, Ma J, Wang Y, Sun X, Keshawarz A, Sooda M, Huan T, Hwang SJ, Bui H, Tejada B, Munson PJ, Demirkale CY, Heard-Costa NL, Pitsillides AN, Peloso GM, Feolo M, Sharopova N, Vasan RS, Levy D. Whole genome DNA and RNA sequencing of whole blood elucidates the genetic architecture of gene expression underlying a wide range of diseases. Sci Rep. 2022 Nov 23; 12(1):20167.View Related Profiles.

Liu, Chunyu
Levy, Daniel
Peloso, Gina
Heard-Costa, Nancy
Hwang, Shih-Jen

PMID: 36424512; PMCID: PMC9686236; DOI: 10.1038/s41598-022-24611-w;

Ma J, Joehanes R, Liu C, Keshawarz A, Hwang SJ, Bui H, Tejada B, Sooda M, Munson PJ, Demirkale CY, Courchesne P, Heard-Costa NL, Pitsillides AN, Feolo M, Sharopova N, Vasan RS, Huan T, Levy D. Elucidating the genetic architecture of DNA methylation to identify promising molecular mechanisms of disease. Sci Rep. 2022 Nov 15; 12(1):19564.View Related Profiles.

Liu, Chunyu
Heard-Costa, Nancy
Hwang, Shih-Jen

PMID: 36380121; PMCID: PMC9664436; DOI: 10.1038/s41598-022-24100-0;

Liu C, Li Y, Nwosu A, Ang TFA, Liu Y, Devine S, Au R, Doraiswamy PM. Sex-specific biomarkers in Alzheimer's disease progression: Framingham Heart Study. Alzheimers Dement (Amst). 2022; 14(1):e12369.View Related Profiles.

Liu, Chunyu
Au, Rhoda
Devine, Sherral
Ang, Ting Fang Alvin

PMID: 36348973; PMCID: PMC9633867; DOI: 10.1002/dad2.12369;

Nannini DR, Zheng Y, Joyce BT, Gao T, Liu L, Jacobs DR, Schreiner P, Liu C, Horvath S, Lu AT, Yaffe K, Sidney S, Greenland P, Lloyd-Jones DM, Hou L. Marijuana use and DNA methylation-based biological age in young adults. Clin Epigenetics. 2022 10 26; 14(1):134.View Related Profiles.

Liu, Chunyu
Lloyd-Jones, Donald

PMID: 36289503; PMCID: PMC9609285; DOI: 10.1186/s13148-022-01359-8;

Uddin MDM, Nguyen NQH, Yu B, Brody JA, Pampana A, Nakao T, Fornage M, Bressler J, Sotoodehnia N, Weinstock JS, Honigberg MC, Nachun D, Bhattacharya R, Griffin GK, Chander V, Gibbs RA, Rotter JI, Liu C, Baccarelli AA, Chasman DI, Whitsel EA, Kiel DP, Murabito JM, Boerwinkle E, Ebert BL, Jaiswal S, Floyd JS, Bick AG, Ballantyne CM, Psaty BM, Natarajan P, Conneely KN. Clonal hematopoiesis of indeterminate potential, DNA methylation, and risk for coronary artery disease. Nat Commun. 2022 09 12; 13(1):5350.View Related Profiles.

Liu, Chunyu
Murabito, Joanne

PMID: 36097025; PMCID: PMC9468335; DOI: 10.1038/s41467-022-33093-3;

Zheng Y, Lunetta KL, Liu C, Katrinli S, Smith AK, Miller MW, Logue MW. An evaluation of the genome-wide false positive rates of common methods for identifying differentially methylated regions using illumina methylation arrays. Epigenetics. 2022 Dec; 17(13):2241-2258.View Related Profiles.

Liu, Chunyu
Lunetta, Kathryn
Logue, Mark
Miller, Mark

PMID: 36047742; PMCID: PMC9665129; DOI: 10.1080/15592294.2022.2115600;

Yuan J, Liu X, Liu C, Ang AFA, Massaro J, Devine SA, Auerbach SH, Blusztajn JK, Au R, Jacques PF. Is dietary choline intake related to dementia and Alzheimer's disease risk: results from the Framingham Heart Study. Am J Clin Nutr. 2022 Aug 02.View Related Profiles.

Liu, Chunyu
Au, Rhoda
Auerbach, Sanford
Devine, Sherral

PMID: 35918258; PMCID: PMC9630864; DOI: 10.1093/ajcn/nqac193;

de Oliveira CM, Pavani JL, Liu C, Balcells M, Capasso R, Alvim RO, Mourão-Júnior CA, Krieger JE, Pereira AC. Comparing different metabolic indexes to predict type 2 diabetes mellitus in a five years follow-up cohort: The Baependi Heart Study. PLoS One. 2022; 17(6):e0267723. PMID: 35657786; PMCID: PMC9165883; DOI: 10.1371/journal.pone.0267723;

Kelly TN, Sun X, He KY, Brown MR, Taliun SAG, Hellwege JN, Irvin MR, Mi X, Brody JA, Franceschini N, Guo X, Hwang SJ, de Vries PS, Gao Y, Moscati A, Nadkarni GN, Yanek LR, Elfassy T, Smith JA, Chung RH, Beitelshees AL, Patki A, Aslibekyan S, Blobner BM, Peralta JM, Assimes TL, Palmas WR, Liu C, Bress AP, Huang Z, Becker LC, Hwa CM, O'Connell JR, Carlson JC, Warren HR, Das S, Giri A, Martin LW, Craig Johnson W, Fox ER, Bottinger EP, Razavi AC, Vaidya D, Chuang LM, Chang YC, Naseri T, Jain D, Kang HM, Hung AM, Srinivasasainagendra V, Snively BM, Gu D, Montasser ME, Reupena MS, Heavner BD, LeFaive J, Hixson JE, Rice KM, Wang FF, Nielsen JB, Huang J, Khan AT, Zhou W, Nierenberg JL, Laurie CC, Armstrong ND, Shi M, Pan Y, Stilp AM, Emery L, Wong Q, Hawley NL, Minster RL, Curran JE, Munroe PB, Weeks DE, North KE, Tracy RP, Kenny EE, Shimbo D, Chakravarti A, Rich SS, Reiner AP, Blangero J, Redline S, Mitchell BD, Rao DC, Ida Chen YD, Kardia SLR, Kaplan RC, Mathias RA, He J, Psaty BM, Fornage M, Loos RJF, Correa A, Boerwinkle E, Rotter JI, Kooperberg C, Edwards TL, Abecasis GR, Zhu X, Levy D, Arnett DK, Morrison AC. Insights From a Large-Scale Whole-Genome Sequencing Study of Systolic Blood Pressure, Diastolic Blood Pressure, and Hypertension. Hypertension. 2022 Aug; 79(8):1656-1667.View Related Profiles.

Liu, Chunyu
Hwang, Shih-Jen

PMID: 35652341; PMCID: PMC9593435; DOI: 10.1161/HYPERTENSIONAHA.122.19324;

Battle SL, Puiu D, Verlouw J, Broer L, Boerwinkle E, Taylor KD, Rotter JI, Rich SS, Grove ML, Pankratz N, Fetterman JL, Liu C, Arking DE. A bioinformatics pipeline for estimating mitochondrial DNA copy number and heteroplasmy levels from whole genome sequencing data. NAR Genom Bioinform. 2022 Jun; 4(2):lqac034.View Related Profiles.

Liu, Chunyu
Fetterman, Jessica

PMID: 35591888; PMCID: PMC9112767; DOI: 10.1093/nargab/lqac034;

Huan T, Nguyen S, Colicino E, Ochoa-Rosales C, Hill WD, Brody JA, Soerensen M, Zhang Y, Baldassari A, Elhadad MA, Toshiko T, Zheng Y, Domingo-Relloso A, Lee DH, Ma J, Yao C, Liu C, Hwang SJ, Joehanes R, Fornage M, Bressler J, van Meurs JBJ, Debrabant B, Mengel-From J, Hjelmborg J, Christensen K, Vokonas P, Schwartz J, Gahrib SA, Sotoodehnia N, Sitlani CM, Kunze S, Gieger C, Peters A, Waldenberger M, Deary IJ, Ferrucci L, Qu Y, Greenland P, Lloyd-Jones DM, Hou L, Bandinelli S, Voortman T, Hermann B, Baccarelli A, Whitsel E, Pankow JS, Levy D. Integrative analysis of clinical and epigenetic biomarkers of mortality. Aging Cell. 2022 Jun; 21(6):e13608.View Related Profiles.

Liu, Chunyu
Lloyd-Jones, Donald
Vokonas, Pantel
Hwang, Shih-Jen

PMID: 35546478; PMCID: PMC9197414; DOI: 10.1111/acel.13608;

Maciel de Oliveira C, França da Rosa F, de Oliveira Alvim R, Mourão Junior CA, Bacells M, Liu C, Pavani J, Capasso R, Lavezzo Dias FA, Eduardo Krieger J, Costa Pereira A. Body mass index is superior to other body adiposity indexes in predicting incident hypertension in a highly admixed sample after 10-year follow-up: The Baependi Heart Study. J Clin Hypertens (Greenwich). 2022 06; 24(6):731-737. PMID: 35543312; PMCID: PMC9180336; DOI: 10.1111/jch.14480;

Hammond MM, Zhang Y, Pathiravasan CH, Lin H, Sardana M, Trinquart L, Benjamin EJ, Borrelli B, Manders ES, Fusco K, Kornej J, Spartano NL, Kheterpal V, Nowak C, McManus DD, Liu C, Murabito JM. Relations Between BMI Trajectories and Habitual Physical Activity Measured by a Smartwatch in the Electronic Cohort of the Framingham Heart Study: Cohort Study. JMIR Cardio. 2022 Apr 27; 6(1):e32348.View Related Profiles.

Borrelli, Belinda
Pathiravasan, Chathurangi
Liu, Chunyu
Benjamin, Emelia
Lin, Honghuang
Murabito, Joanne
Trinquart, Ludovic
Spartano, Nicole

PMID: 35476038; PMCID: PMC9096636; DOI: 10.2196/32348;

Ma J, Liu X, Zhang Y, Cheng H, Gao W, Lai CQ, Gabriel S, Gupta N, Vasan RS, Levy D, Liu C. Diet Quality Scores Are Positively Associated with Whole Blood-Derived Mitochondrial DNA Copy Number in the Framingham Heart Study. J Nutr. 2022 03 03; 152(3):690-697. PMID: 34875096; PMCID: PMC8891175; DOI: 10.1093/jn/nxab418;

He KY, Kelly TN, Wang H, Liang J, Zhu L, Cade BE, Assimes TL, Becker LC, Beitelshees AL, Bielak LF, Bress AP, Brody JA, Chang YC, Chang YC, de Vries PS, Duggirala R, Fox ER, Franceschini N, Furniss AL, Gao Y, Guo X, Haessler J, Hung YJ, Hwang SJ, Irvin MR, Kalyani RR, Liu CT, Liu C, Martin LW, Montasser ME, Muntner PM, Mwasongwe S, Naseri T, Palmas W, Reupena MS, Rice KM, Sheu WH, Shimbo D, Smith JA, Snively BM, Yanek LR, Zhao W, Blangero J, Boerwinkle E, Chen YI, Correa A, Cupples LA, Curran JE, Fornage M, He J, Hou L, Kaplan RC, Kardia SLR, Kenny EE, Kooperberg C, Lloyd-Jones D, Loos RJF, Mathias RA, McGarvey ST, Mitchell BD, North KE, Peyser PA, Psaty BM, Raffield LM, Rao DC, Redline S, Reiner AP, Rich SS, Rotter JI, Taylor KD, Tracy R, Vasan RS, Morrison AC, Levy D, Chakravarti A, Arnett DK, Zhu X. Rare coding variants in RCN3 are associated with blood pressure. BMC Genomics. 2022 Feb 19; 23(1):148.View Related Profiles.

Liu, Ching-Ti
Liu, Chunyu
Lloyd-Jones, Donald
Cupples, L
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PMID: 35183128; PMCID: PMC8858539; DOI: 10.1186/s12864-022-08356-4;

Liu C, Fetterman JL, Sun X, Yan K, Liu P, Luo Y, Ding J, Zhu J, Levy D. Comparison of mitochondrial DNA sequences from whole blood and lymphoblastoid cell lines. Sci Rep. 2022 02 02; 12(1):1801.View Related Profiles.

Liu, Chunyu
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PMID: 35110616; PMCID: PMC8810874; DOI: 10.1038/s41598-022-05814-7;

Chen R, Aldred MA, Xu W, Zein J, Bazeley P, Comhair SAA, Meyers DA, Bleecker ER, Liu C, Erzurum SC, Hu B. Corrigendum to "Comparison of whole genome sequencing and targeted sequencing for mitochondrial DNA" [Mitochondrion 58 (2021) 303-310]. Mitochondrion. 2022 Mar; 63:89. PMID: 35067461; DOI: 10.1016/j.mito.2022.01.004;

Taub MA, Conomos MP, Keener R, Iyer KR, Weinstock JS, Yanek LR, Lane J, Miller-Fleming TW, Brody JA, Raffield LM, McHugh CP, Jain D, Gogarten SM, Laurie CA, Keramati A, Arvanitis M, Smith AV, Heavner B, Barwick L, Becker LC, Bis JC, Blangero J, Bleecker ER, Burchard EG, Celedón JC, Chang YPC, Custer B, Darbar D, de Las Fuentes L, DeMeo DL, Freedman BI, Garrett ME, Gladwin MT, Heckbert SR, Hidalgo BA, Irvin MR, Islam T, Johnson WC, Kaab S, Launer L, Lee J, Liu S, Moscati A, North KE, Peyser PA, Rafaels N, Seidman C, Weeks DE, Wen F, Wheeler MM, Williams LK, Yang IV, Zhao W, Aslibekyan S, Auer PL, Bowden DW, Cade BE, Chen Z, Cho MH, Cupples LA, Curran JE, Daya M, Deka R, Eng C, Fingerlin TE, Guo X, Hou L, Hwang SJ, Johnsen JM, Kenny EE, Levin AM, Liu C, Minster RL, Naseri T, Nouraie M, Reupena MS, Sabino EC, Smith JA, Smith NL, Su JL, Taylor JG, Telen MJ, Tiwari HK, Tracy RP, White MJ, Zhang Y, Wiggins KL, Weiss ST, Vasan RS, Taylor KD, Sinner MF, Silverman EK, Shoemaker MB, Sheu WH, Sciurba F, Schwartz DA, Rotter JI, Roden D, Redline S, Raby BA, Psaty BM, Peralta JM, Palmer ND, Nekhai S, Montgomery CG, Mitchell BD, Meyers DA, McGarvey ST, Mak AC, Loos RJ, Kumar R, Kooperberg C, Konkle BA, Kelly S, Kardia SL, Kaplan R, He J, Gui H, Gilliland FD, Gelb BD, Fornage M, Ellinor PT, de Andrade M, Correa A, Chen YI, Boerwinkle E, Barnes KC, Ashley-Koch AE, Arnett DK, Laurie CC, Abecasis G, Nickerson DA, Wilson JG, Rich SS, Levy D, Ruczinski I, Aviv A, Blackwell TW, Thornton T, O'Connell J, Cox NJ, Perry JA, Armanios M, Battle A, Pankratz N, Reiner AP, Mathias RA. Genetic determinants of telomere length from 109,122 ancestrally diverse whole-genome sequences in TOPMed. Cell Genom. 2022 Jan 12; 2(1).View Related Profiles.

Liu, Chunyu
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PMID: 35530816; PMCID: PMC9075703; DOI: 10.1016/j.xgen.2021.100084;

Zhang Y, Pathiravasan CH, Hammond MM, Liu H, Lin H, Sardana M, Trinquart L, Borrelli B, Manders ES, Kornej J, Spartano NL, Nowak C, Kheterpal V, Benjamin EJ, McManus DD, Murabito JM, Liu C. Comparison of Daily Routines Between Middle-aged and Older Participants With and Those Without Diabetes in the Electronic Framingham Heart Study: Cohort Study. JMIR Diabetes. 2022 Jan 07; 7(1):e29107.View Related Profiles.

Borrelli, Belinda
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Liu, Chunyu
Benjamin, Emelia
Lin, Honghuang
Murabito, Joanne
Trinquart, Ludovic
Spartano, Nicole

PMID: 34994694; PMCID: PMC8783285; DOI: 10.2196/29107;

Wang P, Castellani CA, Yao J, Huan T, Bielak LF, Zhao W, Haessler J, Joehanes R, Sun X, Guo X, Longchamps RJ, Manson JE, Grove ML, Bressler J, Taylor KD, Lappalainen T, Kasela S, Van Den Berg DJ, Hou L, Reiner A, Liu Y, Boerwinkle E, Smith JA, Peyser PA, Fornage M, Rich SS, Rotter JI, Kooperberg C, Arking DE, Levy D, Liu C. Epigenome-wide association study of mitochondrial genome copy number. Hum Mol Genet. 2021 12 27; 31(2):309-319. PMID: 34415308; PMCID: PMC8742999; DOI: 10.1093/hmg/ddab240;

Li J, Joshi P, Ang TFA, Liu C, Auerbach S, Devine S, Au R. Mid- to Late-Life Body Mass Index and Dementia Risk: 38 Years of Follow-up of the Framingham Study. Am J Epidemiol. 2021 12 01; 190(12):2503-2510.View Related Profiles.

Liu, Chunyu
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Auerbach, Sanford
Devine, Sherral
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PMID: 33831181; PMCID: PMC8796797; DOI: 10.1093/aje/kwab096;

Au R, Li J, Liu C. Au et al. Respond to "Body Mass Index and Risk of Dementia". Am J Epidemiol. 2021 12 01; 190(12):2515-2516.View Related Profiles.

Liu, Chunyu
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PMID: 33831143; PMCID: PMC8796810; DOI: 10.1093/aje/kwab097;

Kornej J, Murabito JM, Zhang Y, Liu C, Trinquart L, Sardana M, Manders ES, Hammond MM, Spartano NL, Pathiravasan CH, Wang X, Borrelli B, McManus DD, Benjamin EJ, Lin H. No evidence of association between habitual physical activity and ECG traits: Insights from the electronic Framingham Heart Study. Cardiovasc Digit Health J. 2022 Feb; 3(1):56-58.View Related Profiles.

Borrelli, Belinda
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Liu, Chunyu
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Spartano, Nicole

PMID: 35265935; PMCID: PMC8890067; DOI: 10.1016/j.cvdhj.2021.11.004;

Shields AE, Zhang Y, Argentieri MA, Warner ET, Cozier YC, Liu C, Dye CK, Kent BV, Baccarelli AA, Palmer JR. Stress and spirituality in relation to HPA axis gene methylation among US Black women: results from the Black Women's Health Study and the Study on Stress, Spirituality and Health. Epigenomics. 2021 11; 13(21):1711-1734.View Related Profiles.

Liu, Chunyu
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Cozier, Yvette

PMID: 34726080; PMCID: PMC8579940; DOI: 10.2217/epi-2021-0275;

Liu X, Longchamps RJ, Wiggins KL, Raffield LM, Bielak LF, Zhao W, Pitsillides A, Blackwell TW, Yao J, Guo X, Kurniansyah N, Thyagarajan B, Pankratz N, Rich SS, Taylor KD, Peyser PA, Heckbert SR, Seshadri S, Cupples LA, Boerwinkle E, Grove ML, Larson NB, Smith JA, Vasan RS, Sofer T, Fitzpatrick AL, Fornage M, Ding J, Correa A, Abecasis G, Psaty BM, Wilson JG, Levy D, Rotter JI, Bis JC, Satizabal CL, Arking DE, Liu C. Association of mitochondrial DNA copy number with cardiometabolic diseases. Cell Genom. 2021 Oct 13; 1(1).View Related Profiles.

Liu, Chunyu
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Cupples, L
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PMID: 35036986; PMCID: PMC8758111; DOI: 10.1016/j.xgen.2021.100006;

Sun X, Ho JE, Gao H, Evangelou E, Yao C, Huan T, Hwang SJ, Courchesne P, Larson MG, Levy D, Ma J, Liu C. Associations of Alcohol Consumption with Cardiovascular Disease-Related Proteomic Biomarkers: The Framingham Heart Study. J Nutr. 2021 09 04; 151(9):2574-2582.View Related Profiles.

Liu, Chunyu
Larson, Martin
Hwang, Shih-Jen

PMID: 34159370; PMCID: PMC8417922; DOI: 10.1093/jn/nxab186;

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Liu, Chunyu
Fetterman, Jessica

PMID: 34303007; PMCID: PMC8464516; DOI: 10.1016/j.mito.2021.07.004;

Sardana M, Lin H, Zhang Y, Liu C, Trinquart L, Benjamin EJ, Manders ES, Fusco K, Kornej J, Hammond MM, Spartano N, Pathiravasan CH, Kheterpal V, Nowak C, Borrelli B, Murabito JM, McManus DD. Association of Habitual Physical Activity With Home Blood Pressure in the Electronic Framingham Heart Study (eFHS): Cross-sectional Study. J Med Internet Res. 2021 06 24; 23(6):e25591.View Related Profiles.

Borrelli, Belinda
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Liu, Chunyu
Benjamin, Emelia
Lin, Honghuang
Murabito, Joanne
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Spartano, Nicole

PMID: 34185019; PMCID: PMC8277303; DOI: 10.2196/25591;

Surendran P, Feofanova EV, Lahrouchi N, Ntalla I, Karthikeyan S, Cook J, Chen L, Mifsud B, Yao C, Kraja AT, Cartwright JH, Hellwege JN, Giri A, Tragante V, Thorleifsson G, Liu DJ, Prins BP, Stewart ID, Cabrera CP, Eales JM, Akbarov A, Auer PL, Bielak LF, Bis JC, Braithwaite VS, Brody JA, Daw EW, Warren HR, Drenos F, Nielsen SF, Faul JD, Fauman EB, Fava C, Ferreira T, Foley CN, Franceschini N, Gao H, Giannakopoulou O, Giulianini F, Gudbjartsson DF, Guo X, Harris SE, Havulinna AS, Helgadottir A, Huffman JE, Hwang SJ, Kanoni S, Kontto J, Larson MG, Li-Gao R, Lindström J, Lotta LA, Lu Y, Luan J, Mahajan A, Malerba G, Masca NGD, Mei H, Menni C, Mook-Kanamori DO, Mosen-Ansorena D, Müller-Nurasyid M, Paré G, Paul DS, Perola M, Poveda A, Rauramaa R, Richard M, Richardson TG, Sepúlveda N, Sim X, Smith AV, Smith JA, Staley JR, Stanáková A, Sulem P, Thériault S, Thorsteinsdottir U, Trompet S, Varga TV, Velez Edwards DR, Veronesi G, Weiss S, Willems SM, Yao J, Young R, Yu B, Zhang W, Zhao JH, Zhao W, Zhao W, Evangelou E, Aeschbacher S, Asllanaj E, Blankenberg S, Bonnycastle LL, Bork-Jensen J, Brandslund I, Braund PS, Burgess S, Cho K, Christensen C, Connell J, Mutsert R, Dominiczak AF, Dörr M, Eiriksdottir G, Farmaki AE, Gaziano JM, Grarup N, Grove ML, Hallmans G, Hansen T, Have CT, Heiss G, Jørgensen ME, Jousilahti P, Kajantie E, Kamat M, Käräjämäki A, Karpe F, Koistinen HA, Kovesdy CP, Kuulasmaa K, Laatikainen T, Lannfelt L, Lee IT, Lee WJ, Linneberg A, Martin LW, Moitry M, Nadkarni G, Neville MJ, Palmer CNA, Papanicolaou GJ, Pedersen O, Peters J, Poulter N, Rasheed A, Rasmussen KL, Rayner NW, Mägi R, Renström F, Rettig R, Rossouw J, Schreiner PJ, Sever PS, Sigurdsson EL, Skaaby T, Sun YV, Sundstrom J, Thorgeirsson G, Esko T, Trabetti E, Tsao PS, Tuomi T, Turner ST, Tzoulaki I, Vaartjes I, Vergnaud AC, Willer CJ, Wilson PWF, Witte DR, Yonova-Doing E, Zhang H, Aliya N, Almgren P, Amouyel P, Asselbergs FW, Barnes MR, Blakemore AI, Boehnke M, Bots ML, Bottinger EP, Buring JE, Chambers JC, Chen YI, Chowdhury R, Conen D, Correa A, Davey Smith G, Boer RA, Deary IJ, Dedoussis G, Deloukas P, Di Angelantonio E, Elliott P, Felix SB, Ferrières J, Ford I, Fornage M, Franks PW, Franks S, Frossard P, Gambaro G, Gaunt TR, Groop L, Gudnason V, Harris TB, Hayward C, Hennig BJ, Herzig KH, Ingelsson E, Tuomilehto J, Järvelin MR, Jukema JW, Kardia SLR, Kee F, Kooner JS, Kooperberg C, Launer LJ, Lind L, Loos RJF, Majumder AAS, Laakso M, McCarthy MI, Melander O, Mohlke KL, Murray AD, Nordestgaard BG, Orho-Melander M, Packard CJ, Padmanabhan S, Palmas W, Polasek O, Porteous DJ, Prentice AM, Province MA, Relton CL, Rice K, Ridker PM, Rolandsson O, Rosendaal FR, Rotter JI, Rudan I, Salomaa V, Samani NJ, Sattar N, Sheu WH, Smith BH, Soranzo N, Spector TD, Starr JM, Sebert S, Taylor KD, Lakka TA, Timpson NJ, Tobin MD, van der Harst P, van der Meer P, Ramachandran VS, Verweij N, Virtamo J, Völker U, Weir DR, Zeggini E, Charchar FJ, Wareham NJ, Langenberg C, Tomaszewski M, Butterworth AS, Caulfield MJ, Danesh J, Edwards TL, Holm H, Hung AM, Lindgren CM, Liu C, Manning AK, Morris AP, Morrison AC, O'Donnell CJ, Psaty BM, Saleheen D, Stefansson K, Boerwinkle E, Chasman DI, Levy D, Newton-Cheh C, Munroe PB, Howson JMM. Publisher Correction: Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals. Nat Genet. 2021 May; 53(5):762.View Related Profiles.

O'Donnell, Christopher
Liu, Chunyu
Gaziano, J. Michael
Buring, Julie
Larson, Martin
Hwang, Shih-Jen
Ramachandran, Vasan

PMID: 33727701

Ding EY, Pathiravasan CH, Schramm E, Borrelli B, Liu C, Trinquart L, Kornej J, Benjamin EJ, Murabito JM, McManus DD. Design, deployment, and usability of a mobile system for cardiovascular health monitoring within the electronic Framingham Heart Study. Cardiovasc Digit Health J. 2021 Jun; 2(3):171-178.View Related Profiles.

Borrelli, Belinda
Pathiravasan, Chathurangi
Liu, Chunyu
Benjamin, Emelia
Murabito, Joanne
Trinquart, Ludovic

PMID: 35265906; PMCID: PMC8890046; DOI: 10.1016/j.cvdhj.2021.04.001;

Taliun D, Harris DN, Kessler MD, Carlson J, Szpiech ZA, Torres R, Taliun SAG, Corvelo A, Gogarten SM, Kang HM, Pitsillides AN, LeFaive J, Lee SB, Tian X, Browning BL, Das S, Emde AK, Clarke WE, Loesch DP, Shetty AC, Blackwell TW, Smith AV, Wong Q, Liu X, Conomos MP, Bobo DM, Aguet F, Albert C, Alonso A, Ardlie KG, Arking DE, Aslibekyan S, Auer PL, Barnard J, Barr RG, Barwick L, Becker LC, Beer RL, Benjamin EJ, Bielak LF, Blangero J, Boehnke M, Bowden DW, Brody JA, Burchard EG, Cade BE, Casella JF, Chalazan B, Chasman DI, Chen YI, Cho MH, Choi SH, Chung MK, Clish CB, Correa A, Curran JE, Custer B, Darbar D, Daya M, de Andrade M, DeMeo DL, Dutcher SK, Ellinor PT, Emery LS, Eng C, Fatkin D, Fingerlin T, Forer L, Fornage M, Franceschini N, Fuchsberger C, Fullerton SM, Germer S, Gladwin MT, Gottlieb DJ, Guo X, Hall ME, He J, Heard-Costa NL, Heckbert SR, Irvin MR, Johnsen JM, Johnson AD, Kaplan R, Kardia SLR, Kelly T, Kelly S, Kenny EE, Kiel DP, Klemmer R, Konkle BA, Kooperberg C, Köttgen A, Lange LA, Lasky-Su J, Levy D, Lin X, Lin KH, Liu C, Loos RJF, Garman L, Gerszten R, Lubitz SA, Lunetta KL, Mak ACY, Manichaikul A, Manning AK, Mathias RA, McManus DD, McGarvey ST, Meigs JB, Meyers DA, Mikulla JL, Minear MA, Mitchell BD, Mohanty S, Montasser ME, Montgomery C, Morrison AC, Murabito JM, Natale A, Natarajan P, Nelson SC, North KE, O'Connell JR, Palmer ND, Pankratz N, Peloso GM, Peyser PA, Pleiness J, Post WS, Psaty BM, Rao DC, Redline S, Reiner AP, Roden D, Rotter JI, Ruczinski I, Sarnowski C, Schoenherr S, Schwartz DA, Seo JS, Seshadri S, Sheehan VA, Sheu WH, Shoemaker MB, Smith NL, Smith JA, Sotoodehnia N, Stilp AM, Tang W, Taylor KD, Telen M, Thornton TA, Tracy RP, Van Den Berg DJ, Vasan RS, Viaud-Martinez KA, Vrieze S, Weeks DE, Weir BS, Weiss ST, Weng LC, Willer CJ, Zhang Y, Zhao X, Arnett DK, Ashley-Koch AE, Barnes KC, Boerwinkle E, Gabriel S, Gibbs R, Rice KM, Rich SS, Silverman EK, Qasba P, Gan W, Papanicolaou GJ, Nickerson DA, Browning SR, Zody MC, Zöllner S, Wilson JG, Cupples LA, Laurie CC, Jaquish CE, Hernandez RD, O'Connor TD, Abecasis GR. Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program. Nature. 2021 02; 590(7845):290-299.View Related Profiles.

Liu, Chunyu
Benjamin, Emelia
Peloso, Gina
Murabito, Joanne
Lunetta, Kathryn
Cupples, L
Heard-Costa, Nancy
Choi, Seung Hoan
Seshadri, Sudha

PMID: 33568819; PMCID: PMC7875770; DOI: 10.1038/s41586-021-03205-y;

Chen R, Aldred MA, Xu W, Zein J, Bazeley P, Comhair SAA, Meyers DA, Bleecker ER, Liu C, Erzurum SC, Hu B. Comparison of whole genome sequencing and targeted sequencing for mitochondrial DNA. Mitochondrion. 2021 05; 58:303-310. PMID: 33513442; PMCID: PMC8354572; DOI: 10.1016/j.mito.2021.01.006;

Pathiravasan CH, Zhang Y, Trinquart L, Benjamin EJ, Borrelli B, McManus DD, Kheterpal V, Lin H, Sardana M, Hammond MM, Spartano NL, Dunn AL, Schramm E, Nowak C, Manders ES, Liu H, Kornej J, Liu C, Murabito JM. Adherence of Mobile App-Based Surveys and Comparison With Traditional Surveys: eCohort Study. J Med Internet Res. 2021 01 20; 23(1):e24773.View Related Profiles.

Borrelli, Belinda
Pathiravasan, Chathurangi
Liu, Chunyu
Benjamin, Emelia
Lin, Honghuang
Murabito, Joanne
Trinquart, Ludovic
Spartano, Nicole

PMID: 33470944; PMCID: PMC7857942; DOI: 10.2196/24773;

Corlin L, Liu C, Lin H, Leone D, Yang Q, Ngo D, Levy D, Cupples LA, Gerszten RE, Larson MG, Vasan RS. Proteomic Signatures of Lifestyle Risk Factors for Cardiovascular Disease: A Cross-Sectional Analysis of the Plasma Proteome in the Framingham Heart Study. J Am Heart Assoc. 2021 01 05; 10(1):e018020.View Related Profiles.

Liu, Chunyu
Leone, Dominick
Lin, Honghuang
Cupples, L
Corlin, Laura
Larson, Martin
Yang, Qiong

PMID: 33372532; PMCID: PMC7955453; DOI: 10.1161/JAHA.120.018020;

Surendran P, Feofanova EV, Lahrouchi N, Ntalla I, Karthikeyan S, Cook J, Chen L, Mifsud B, Yao C, Kraja AT, Cartwright JH, Hellwege JN, Giri A, Tragante V, Thorleifsson G, Liu DJ, Prins BP, Stewart ID, Cabrera CP, Eales JM, Akbarov A, Auer PL, Bielak LF, Bis JC, Braithwaite VS, Brody JA, Daw EW, Warren HR, Drenos F, Nielsen SF, Faul JD, Fauman EB, Fava C, Ferreira T, Foley CN, Franceschini N, Gao H, Giannakopoulou O, Giulianini F, Gudbjartsson DF, Guo X, Harris SE, Havulinna AS, Helgadottir A, Huffman JE, Hwang SJ, Kanoni S, Kontto J, Larson MG, Li-Gao R, Lindström J, Lotta LA, Lu Y, Luan J, Mahajan A, Malerba G, Masca NGD, Mei H, Menni C, Mook-Kanamori DO, Mosen-Ansorena D, Müller-Nurasyid M, Paré G, Paul DS, Perola M, Poveda A, Rauramaa R, Richard M, Richardson TG, Sepúlveda N, Sim X, Smith AV, Smith JA, Staley JR, Stanáková A, Sulem P, Thériault S, Thorsteinsdottir U, Trompet S, Varga TV, Velez Edwards DR, Veronesi G, Weiss S, Willems SM, Yao J, Young R, Yu B, Zhang W, Zhao JH, Zhao W, Zhao W, Evangelou E, Aeschbacher S, Asllanaj E, Blankenberg S, Bonnycastle LL, Bork-Jensen J, Brandslund I, Braund PS, Burgess S, Cho K, Christensen C, Connell J, Mutsert R, Dominiczak AF, Dörr M, Eiriksdottir G, Farmaki AE, Gaziano JM, Grarup N, Grove ML, Hallmans G, Hansen T, Have CT, Heiss G, Jørgensen ME, Jousilahti P, Kajantie E, Kamat M, Käräjämäki A, Karpe F, Koistinen HA, Kovesdy CP, Kuulasmaa K, Laatikainen T, Lannfelt L, Lee IT, Lee WJ, Linneberg A, Martin LW, Moitry M, Nadkarni G, Neville MJ, Palmer CNA, Papanicolaou GJ, Pedersen O, Peters J, Poulter N, Rasheed A, Rasmussen KL, Rayner NW, Mägi R, Renström F, Rettig R, Rossouw J, Schreiner PJ, Sever PS, Sigurdsson EL, Skaaby T, Sun YV, Sundstrom J, Thorgeirsson G, Esko T, Trabetti E, Tsao PS, Tuomi T, Turner ST, Tzoulaki I, Vaartjes I, Vergnaud AC, Willer CJ, Wilson PWF, Witte DR, Yonova-Doing E, Zhang H, Aliya N, Almgren P, Amouyel P, Asselbergs FW, Barnes MR, Blakemore AI, Boehnke M, Bots ML, Bottinger EP, Buring JE, Chambers JC, Chen YI, Chowdhury R, Conen D, Correa A, Davey Smith G, Boer RA, Deary IJ, Dedoussis G, Deloukas P, Di Angelantonio E, Elliott P, Felix SB, Ferrières J, Ford I, Fornage M, Franks PW, Franks S, Frossard P, Gambaro G, Gaunt TR, Groop L, Gudnason V, Harris TB, Hayward C, Hennig BJ, Herzig KH, Ingelsson E, Tuomilehto J, Järvelin MR, Jukema JW, Kardia SLR, Kee F, Kooner JS, Kooperberg C, Launer LJ, Lind L, Loos RJF, Majumder AAS, Laakso M, McCarthy MI, Melander O, Mohlke KL, Murray AD, Nordestgaard BG, Orho-Melander M, Packard CJ, Padmanabhan S, Palmas W, Polasek O, Porteous DJ, Prentice AM, Province MA, Relton CL, Rice K, Ridker PM, Rolandsson O, Rosendaal FR, Rotter JI, Rudan I, Salomaa V, Samani NJ, Sattar N, Sheu WH, Smith BH, Soranzo N, Spector TD, Starr JM, Sebert S, Taylor KD, Lakka TA, Timpson NJ, Tobin MD, van der Harst P, van der Meer P, Ramachandran VS, Verweij N, Virtamo J, Völker U, Weir DR, Zeggini E, Charchar FJ, Wareham NJ, Langenberg C, Tomaszewski M, Butterworth AS, Caulfield MJ, Danesh J, Edwards TL, Holm H, Hung AM, Lindgren CM, Liu C, Manning AK, Morris AP, Morrison AC, O'Donnell CJ, Psaty BM, Saleheen D, Stefansson K, Boerwinkle E, Chasman DI, Levy D, Newton-Cheh C, Munroe PB, Howson JMM. Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals. Nat Genet. 2020 12; 52(12):1314-1332.View Related Profiles.

O'Donnell, Christopher
Liu, Chunyu
Gaziano, J. Michael
Buring, Julie
Larson, Martin
Hwang, Shih-Jen
Ramachandran, Vasan

PMID: 33230300; PMCID: PMC7610439; DOI: 10.1038/s41588-020-00713-x;

Sarnowski C, Huan T, Jain D, Liu C, Yao C, Joehanes R, Levy D, Dupuis J. JEM: A joint test to estimate the effect of multiple genetic variants on DNA methylation. Genet Epidemiol. 2021 04; 45(3):280-292.View Related Profiles.

Liu, Chunyu
Levy, Daniel
Dupuis, Josee

PMID: 33038041; PMCID: PMC8005415; DOI: 10.1002/gepi.22369;

Castellani CA, Longchamps RJ, Sumpter JA, Newcomb CE, Lane JA, Grove ML, Bressler J, Brody JA, Floyd JS, Bartz TM, Taylor KD, Wang P, Tin A, Coresh J, Pankow JS, Fornage M, Guallar E, O'Rourke B, Pankratz N, Liu C, Levy D, Sotoodehnia N, Boerwinkle E, Arking DE. Mitochondrial DNA copy number can influence mortality and cardiovascular disease via methylation of nuclear DNA CpGs. Genome Med. 2020 09 28; 12(1):84. PMID: 32988399; PMCID: PMC7523322; DOI: 10.1186/s13073-020-00778-7;

Andersson C, Liu C, Cheng S, Wang TJ, Gerszten RE, Larson MG, Vasan RS. Metabolomic signatures of cardiac remodelling and heart failure risk in the community. ESC Heart Fail. 2020 Dec; 7(6):3707-3715.View Related Profiles.

Liu, Chunyu
Larson, Martin

PMID: 32909388; PMCID: PMC7754777; DOI: 10.1002/ehf2.12923;

Lin H, Sardana M, Zhang Y, Liu C, Trinquart L, Benjamin EJ, Manders ES, Fusco K, Kornej J, Hammond MM, Spartano NL, Pathiravasan CH, Kheterpal V, Nowak C, Borrelli B, Murabito JM, McManus DD. Association of Habitual Physical Activity With Cardiovascular Disease Risk. Circ Res. 2020 10 23; 127(10):1253-1260.View Related Profiles.

Borrelli, Belinda
Pathiravasan, Chathurangi
Liu, Chunyu
Benjamin, Emelia
Lin, Honghuang
Murabito, Joanne
Trinquart, Ludovic
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PMID: 32842915; PMCID: PMC7581630; DOI: 10.1161/CIRCRESAHA.120.317578;

de Oliveira CM, Pavani J, Liu C, de Oliveira Alvim R, Balcells M, Mourão-Junior CA, Krieger JE, da Costa Pereira A. Triglyceride glucose index as a tool to motivate early lifestyle modification in young adults at diabetes risk: The Baependi Heart Study. Prev Med Rep. 2020 Dec; 20:101172. PMID: 32874826; PMCID: PMC7452098; DOI: 10.1016/j.pmedr.2020.101172;

de Oliveira CM, Viater Tureck L, Alvares D, Liu C, Horimoto ARVR, Balcells M, de Oliveira Alvim R, Krieger JE, Pereira AC. Relationship between marital status and incidence of type 2 diabetes mellitus in a Brazilian rural population: The Baependi Heart Study. PLoS One. 2020; 15(8):e0236869. PMID: 32745127; PMCID: PMC7398527; DOI: 10.1371/journal.pone.0236869;

Colicino E, Marioni R, Ward-Caviness C, Gondalia R, Guan W, Chen B, Tsai PC, Huan T, Xu G, Golareh A, Schwartz J, Vokonas P, Just A, Starr JM, McRae AF, Wray NR, Visscher PM, Bressler J, Zhang W, Tanaka T, Moore AZ, Pilling LC, Zhang G, Stewart JD, Li Y, Hou L, Castillo-Fernandez J, Spector T, Kiel DP, Murabito JM, Liu C, Mendelson M, Assimes T, Absher D, Tsaho PS, Lu AT, Ferrucci L, Wilson R, Waldenberger M, Prokisch H, Bandinelli S, Bell JT, Levy D, Deary IJ, Horvath S, Pankow J, Peters A, Whitsel EA, Baccarelli A. Blood DNA methylation sites predict death risk in a longitudinal study of 12, 300 individuals. Aging (Albany NY). 2020 07 22; 12(14):14092-14124.View Related Profiles.

Liu, Chunyu
Murabito, Joanne
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PMID: 32697766; PMCID: PMC7425458; DOI: 10.18632/aging.103408;

Ma J, Rebholz CM, Braun KVE, Reynolds LM, Aslibekyan S, Xia R, Biligowda NG, Huan T, Liu C, Mendelson MM, Joehanes R, Hu EA, Vitolins MZ, Wood AC, Lohman K, Ochoa-Rosales C, van Meurs J, Uitterlinden A, Liu Y, Elhadad MA, Heier M, Waldenberger M, Peters A, Colicino E, Whitsel EA, Baldassari A, Gharib SA, Sotoodehnia N, Brody JA, Sitlani CM, Tanaka T, Hill WD, Corley J, Deary IJ, Zhang Y, Schöttker B, Brenner H, Walker ME, Ye S, Nguyen S, Pankow J, Demerath EW, Zheng Y, Hou L, Liang L, Lichtenstein AH, Hu FB, Fornage M, Voortman T, Levy D. Whole Blood DNA Methylation Signatures of Diet Are Associated With Cardiovascular Disease Risk Factors and All-Cause Mortality. Circ Genom Precis Med. 2020 08; 13(4):e002766.View Related Profiles.

Liu, Chunyu
Walker, Maura

PMID: 32525743; PMCID: PMC7442697; DOI: 10.1161/CIRCGEN.119.002766;

De Oliveira CM, Tureck LV, Alvares D, Liu C, Horimoto ARVR, de Oliveira Alvim R, Krieger JE, Pereira AC. Cardiometabolic risk factors correlated with the incidence of dysglycaemia in a Brazilian normoglycaemic sample: the Baependi Heart Study cohort. Diabetol Metab Syndr. 2020; 12:6. PMID: 31956344; PMCID: PMC6958593; DOI: 10.1186/s13098-019-0512-0;

Yousefi PD, Richmond R, Langdon R, Ness A, Liu C, Levy D, Relton C, Suderman M, Zuccolo L. Validation and characterisation of a DNA methylation alcohol biomarker across the life course. Clin Epigenetics. 2019 11 27; 11(1):163. PMID: 31775873; PMCID: PMC6880546; DOI: 10.1186/s13148-019-0753-7;

Andersson C, Lin H, Liu C, Levy D, Mitchell GF, Larson MG, Vasan RS. Integrated Multiomics Approach to Identify Genetic Underpinnings of Heart Failure and Its Echocardiographic Precursors: Framingham Heart Study. Circ Genom Precis Med. 2019 12; 12(12):e002489.View Related Profiles.

Liu, Chunyu
Lin, Honghuang
Larson, Martin

PMID: 31703168; DOI: 10.1161/CIRCGEN.118.002489;

Huan T, Joehanes R, Song C, Peng F, Guo Y, Mendelson M, Yao C, Liu C, Ma J, Richard M, Agha G, Guan W, Almli LM, Conneely KN, Keefe J, Hwang SJ, Johnson AD, Fornage M, Liang L, Levy D. Genome-wide identification of DNA methylation QTLs in whole blood highlights pathways for cardiovascular disease. Nat Commun. 2019 09 19; 10(1):4267.View Related Profiles.

Liu, Chunyu
Levy, Daniel
Hwang, Shih-Jen

PMID: 31537805; PMCID: PMC6753136; DOI: 10.1038/s41467-019-12228-z;

Cardona A, Day FR, Perry JRB, Loh M, Chu AY, Lehne B, Paul DS, Lotta LA, Stewart ID, Kerrison ND, Scott RA, Khaw KT, Forouhi NG, Langenberg C, Liu C, Mendelson MM, Levy D, Beck S, Leslie RD, Dupuis J, Meigs JB, Kooner JS, Pihlajamäki J, Vaag A, Perfilyev A, Ling C, Hivert MF, Chambers JC, Wareham NJ, Ong KK. Epigenome-Wide Association Study of Incident Type 2 Diabetes in a British Population: EPIC-Norfolk Study. Diabetes. 2019 12; 68(12):2315-2326.View Related Profiles.

Liu, Chunyu
Dupuis, Josee

PMID: 31506343; PMCID: PMC6868468; DOI: 10.2337/db18-0290;

Agha G, Mendelson MM, Ward-Caviness CK, Joehanes R, Huan T, Gondalia R, Salfati E, Brody JA, Fiorito G, Bressler J, Chen BH, Ligthart S, Guarrera S, Colicino E, Just AC, Wahl S, Gieger C, Vandiver AR, Tanaka T, Hernandez DG, Pilling LC, Singleton AB, Sacerdote C, Krogh V, Panico S, Tumino R, Li Y, Zhang G, Stewart JD, Floyd JS, Wiggins KL, Rotter JI, Multhaup M, Bakulski K, Horvath S, Tsao PS, Absher DM, Vokonas P, Hirschhorn J, Fallin MD, Liu C, Bandinelli S, Boerwinkle E, Dehghan A, Schwartz JD, Psaty BM, Feinberg AP, Hou L, Ferrucci L, Sotoodehnia N, Matullo G, Peters A, Fornage M, Assimes TL, Whitsel EA, Levy D, Baccarelli AA. Blood Leukocyte DNA Methylation Predicts Risk of Future Myocardial Infarction and Coronary Heart Disease. Circulation. 2019 08 20; 140(8):645-657.View Related Profiles.

Liu, Chunyu
Vokonas, Pantel

PMID: 31424985; PMCID: PMC6812683; DOI: 10.1161/CIRCULATIONAHA.118.039357;

Salinas J, Lin H, Aparico HJ, Huan T, Liu C, Rong J, Beiser A, Himali JJ, Freedman JE, Larson MG, Rosand J, Soreq H, Levy D, Seshadri S. Whole blood microRNA expression associated with stroke: Results from the Framingham Heart Study. PLoS One. 2019; 14(8):e0219261.View Related Profiles.

Beiser, Alexa
Liu, Chunyu
Lin, Honghuang
Himali, Jayandra
Larson, Martin
Seshadri, Sudha

PMID: 31393881; PMCID: PMC6687152; DOI: 10.1371/journal.pone.0219261;

Evangelou E, Gao H, Chu C, Ntritsos G, Blakeley P, Butts AR, Pazoki R, Suzuki H, Koskeridis F, Yiorkas AM, Karaman I, Elliott J, Luo Q, Aeschbacher S, Bartz TM, Baumeister SE, Braund PS, Brown MR, Brody JA, Clarke TK, Dimou N, Faul JD, Homuth G, Jackson AU, Kentistou KA, Joshi PK, Lemaitre RN, Lind PA, Lyytikäinen LP, Mangino M, Milaneschi Y, Nelson CP, Nolte IM, Perälä MM, Polasek O, Porteous D, Ratliff SM, Smith JA, Stancáková A, Teumer A, Tuominen S, Thériault S, Vangipurapu J, Whitfield JB, Wood A, Yao J, Yu B, Zhao W, Arking DE, Auvinen J, Liu C, Männikkö M, Risch L, Rotter JI, Snieder H, Veijola J, Blakemore AI, Boehnke M, Campbell H, Conen D, Eriksson JG, Grabe HJ, Guo X, van der Harst P, Hartman CA, Hayward C, Heath AC, Jarvelin MR, Kähönen M, Kardia SLR, Kühne M, Kuusisto J, Laakso M, Lahti J, Lehtimäki T, McIntosh AM, Mohlke KL, Morrison AC, Martin NG, Oldehinkel AJ, Penninx BWJH, Psaty BM, Raitakari OT, Rudan I, Samani NJ, Scott LJ, Spector TD, Verweij N, Weir DR, Wilson JF, Levy D, Tzoulaki I, Bell JD, Matthews PM, Rothenfluh A, Desrivières S, Schumann G, Elliott P. New alcohol-related genes suggest shared genetic mechanisms with neuropsychiatric disorders. Nat Hum Behav. 2019 09; 3(9):950-961. PMID: 31358974; PMCID: PMC7711277; DOI: 10.1038/s41562-019-0653-z;

Huan T, Mendelson M, Joehanes R, Yao C, Liu C, Song C, Bhattacharya A, Rong J, Tanriverdi K, Keefe J, Murabito JM, Courchesne P, Larson MG, Freedman JE, Levy D. Epigenome-wide association study of DNA methylation and microRNA expression highlights novel pathways for human complex traits. Epigenetics. 2020 Jan - Feb; 15(1-2):183-198.View Related Profiles.

Liu, Chunyu
Murabito, Joanne
Larson, Martin

PMID: 31282290; PMCID: PMC6961684; DOI: 10.1080/15592294.2019.1640547;

Müller CP, Chu C, Qin L, Liu C, Xu B, Gao H, Ruggeri B, Hieber S, Schneider J, Jia T, Tay N, Akira S, Satoh T, Banaschewski T, Bokde ALW, Bromberg U, Büchel C, Quinlan EB, Flor H, Frouin V, Garavan H, Gowland P, Heinz A, Ittermann B, Martinot JL, Martinot MP, Artiges E, Lemaitre H, Nees F, Papadopoulos Orfanos D, Paus T, Poustka L, Millenet S, Fröhner JH, Smolka MN, Walter H, Whelan R, Bakalkin G, Liu Y, Desrivières S, Elliott P, Eulenburg V, Levy D, Crews F, Schumann G. The Cortical Neuroimmune Regulator TANK Affects Emotional Processing and Enhances Alcohol Drinking: A Translational Study. Cereb Cortex. 2019 04 01; 29(4):1736-1751. PMID: 30721969; PMCID: PMC6430980; DOI: 10.1093/cercor/bhy341;

Ma J, Nano J, Ding J, Zheng Y, Hennein R, Liu C, Speliotes EK, Huan T, Song C, Mendelson MM, Joehanes R, Long MT, Liang L, Smith JA, Reynolds LM, Ghanbari M, Muka T, van Meurs JBJ, Alferink LJM, Franco OH, Dehghan A, Ratliff S, Zhao W, Bielak L, Kardia SLR, Peyser PA, Ning H, VanWagner LB, Lloyd-Jones DM, Carr JJ, Greenland P, Lichtenstein AH, Hu FB, Liu Y, Hou L, Darwish Murad S, Levy D. A Peripheral Blood DNA Methylation Signature of Hepatic Fat Reveals a Potential Causal Pathway for Nonalcoholic Fatty Liver Disease. Diabetes. 2019 05; 68(5):1073-1083.View Related Profiles.

Liu, Chunyu
Lloyd-Jones, Donald
Long, Michelle

PMID: 30936141; PMCID: PMC6477898; DOI: 10.2337/DB18-1193;

Hennein R, Liu C, McKeown NM, Hoffmann U, Long MT, Levy D, Ma J. Increased Diet Quality is Associated with Long-Term Reduction of Abdominal and Pericardial Fat. Obesity (Silver Spring). 2019 04; 27(4):670-677.View Related Profiles.

Liu, Chunyu
Long, Michelle

PMID: 30825267; PMCID: PMC6430652; DOI: 10.1002/oby.22427;

Ma J, Nano J, Ding J, Zheng Y, Hennein R, Liu C, Speliotes EK, Huan T, Song C, Mendelson MM, Joehanes R, Long MT, Liang L, Smith JA, Reynolds L, Ghanbari M, Muka T, van Meurs J, Alferink LJM, Franco OH, Dehghan A, Ratliff S, Zhao W, Bielak L, Kardia SL, Peyser PA, Ning H, VanWagner LB, Lloyd-Jones DM, Carr JJ, Greenland P, Lichtenstein AH, Hu FB, Liu Y, Hou L, Murad SD, Levy D. A Peripheral Blood DNA Methylation Signature of Hepatic Fat Reveals a Potential Causal Pathway for Non-Alcoholic Fatty Liver Disease. Diabetes. 2019 Feb 22.View Related Profiles.

Liu, Chunyu
Long, Michelle

PMID: 30796027

He KY, Li X, Kelly TN, Liang J, Cade BE, Assimes TL, Becker LC, Beitelshees AL, Bress AP, Chang YC, Chen YI, de Vries PS, Fox ER, Franceschini N, Furniss A, Gao Y, Guo X, Haessler J, Hwang SJ, Irvin MR, Kalyani RR, Liu CT, Liu C, Martin LW, Montasser ME, Muntner PM, Mwasongwe S, Palmas W, Reiner AP, Shimbo D, Smith JA, Snively BM, Yanek LR, Boerwinkle E, Correa A, Cupples LA, He J, Kardia SLR, Kooperberg C, Mathias RA, Mitchell BD, Psaty BM, Vasan RS, Rao DC, Rich SS, Rotter JI, Wilson JG, Chakravarti A, Morrison AC, Levy D, Arnett DK, Redline S, Zhu X. Leveraging linkage evidence to identify low-frequency and rare variants on 16p13 associated with blood pressure using TOPMed whole genome sequencing data. Hum Genet. 2019 Feb; 138(2):199-210.View Related Profiles.

Liu, Ching-Ti
Liu, Chunyu
Cupples, L
Hwang, Shih-Jen

PMID: 30671673; PMCID: PMC6404531; DOI: 10.1007/s00439-019-01975-0;

Kraja AT, Liu C, Fetterman JL, Graff M, Have CT, Gu C, Yanek LR, Feitosa MF, Arking DE, Chasman DI, Young K, Ligthart S, Hill WD, Weiss S, Luan J, Giulianini F, Li-Gao R, Hartwig FP, Lin SJ, Wang L, Richardson TG, Yao J, Fernandez EP, Ghanbari M, Wojczynski MK, Lee WJ, Argos M, Armasu SM, Barve RA, Ryan KA, An P, Baranski TJ, Bielinski SJ, Bowden DW, Broeckel U, Christensen K, Chu AY, Corley J, Cox SR, Uitterlinden AG, Rivadeneira F, Cropp CD, Daw EW, van Heemst D, de Las Fuentes L, Gao H, Tzoulaki I, Ahluwalia TS, de Mutsert R, Emery LS, Erzurumluoglu AM, Perry JA, Fu M, Forouhi NG, Gu Z, Hai Y, Harris SE, Hemani G, Hunt SC, Irvin MR, Jonsson AE, Justice AE, Kerrison ND, Larson NB, Lin KH, Love-Gregory LD, Mathias RA, Lee JH, Nauck M, Noordam R, Ong KK, Pankow J, Patki A, Pattie A, Petersmann A, Qi Q, Ribel-Madsen R, Rohde R, Sandow K, Schnurr TM, Sofer T, Starr JM, Taylor AM, Teumer A, Timpson NJ, de Haan HG, Wang Y, Weeke PE, Williams C, Wu H, Yang W, Zeng D, Witte DR, Weir BS, Wareham NJ, Vestergaard H, Turner ST, Torp-Pedersen C, Stergiakouli E, Sheu WH, Rosendaal FR, Ikram MA, Franco OH, Ridker PM, Perls TT, Pedersen O, Nohr EA, Newman AB, Linneberg A, Langenberg C, Kilpeläinen TO, Kardia SLR, Jørgensen ME, Jørgensen T, Sørensen TIA, Homuth G, Hansen T, Goodarzi MO, Deary IJ, Christensen C, Chen YI, Chakravarti A, Brandslund I, Bonnelykke K, Taylor KD, Wilson JG, Rodriguez S, Davies G, Horta BL, Thyagarajan B, Rao DC, Grarup N, Davila-Roman VG, Hudson G, Guo X, Arnett DK, Hayward C, Vaidya D, Mook-Kanamori DO, Tiwari HK, Levy D, Loos RJF, Dehghan A, Elliott P, Malik AN, Scott RA, Becker DM, de Andrade M, Province MA, Meigs JB, Rotter JI, North KE. Associations of Mitochondrial and Nuclear Mitochondrial Variants and Genes with Seven Metabolic Traits. Am J Hum Genet. 2019 01 03; 104(1):112-138.View Related Profiles.

Liu, Chunyu
Fetterman, Jessica
Argos, Maria
Perls, Thomas

PMID: 30595373; PMCID: PMC6323610; DOI: 10.1016/j.ajhg.2018.12.001;

Giri A, Hellwege JN, Keaton JM, Park J, Qiu C, Warren HR, Torstenson ES, Kovesdy CP, Sun YV, Wilson OD, Robinson-Cohen C, Roumie CL, Chung CP, Birdwell KA, Damrauer SM, DuVall SL, Klarin D, Cho K, Wang Y, Evangelou E, Cabrera CP, Wain LV, Shrestha R, Mautz BS, Akwo EA, Sargurupremraj M, Debette S, Boehnke M, Scott LJ, Luan J, Zhao JH, Willems SM, Thériault S, Shah N, Oldmeadow C, Almgren P, Li-Gao R, Verweij N, Boutin TS, Mangino M, Ntalla I, Feofanova E, Surendran P, Cook JP, Karthikeyan S, Lahrouchi N, Liu C, Sepúlveda N, Richardson TG, Kraja A, Amouyel P, Farrall M, Poulter NR, Laakso M, Zeggini E, Sever P, Scott RA, Langenberg C, Wareham NJ, Conen D, Palmer CNA, Attia J, Chasman DI, Ridker PM, Melander O, Mook-Kanamori DO, Harst PV, Cucca F, Schlessinger D, Hayward C, Spector TD, Jarvelin MR, Hennig BJ, Timpson NJ, Wei WQ, Smith JC, Xu Y, Matheny ME, Siew EE, Lindgren C, Herzig KH, Dedoussis G, Denny JC, Psaty BM, Howson JMM, Munroe PB, Newton-Cheh C, Caulfield MJ, Elliott P, Gaziano JM, Concato J, Wilson PWF, Tsao PS, Velez Edwards DR, Susztak K, O'Donnell CJ, Hung AM, Edwards TL. Trans-ethnic association study of blood pressure determinants in over 750,000 individuals. Nat Genet. 2019 01; 51(1):51-62.View Related Profiles.

O'Donnell, Christopher
Liu, Chunyu
Gaziano, J. Michael

PMID: 30578418; PMCID: PMC6365102; DOI: 10.1038/s41588-018-0303-9;

Yao C, Chen G, Song C, Keefe J, Mendelson M, Huan T, Sun BB, Laser A, Maranville JC, Wu H, Ho JE, Courchesne P, Lyass A, Larson MG, Gieger C, Graumann J, Johnson AD, Danesh J, Runz H, Hwang SJ, Liu C, Butterworth AS, Suhre K, Levy D. Author Correction: Genome-wide mapping of plasma protein QTLs identifies putatively causal genes and pathways for cardiovascular disease. Nat Commun. 2018 09 18; 9(1):3853.View Related Profiles.

Liu, Chunyu
Levy, Daniel
Larson, Martin
Hwang, Shih-Jen

PMID: 30228274; PMCID: PMC6143533; DOI: 10.1038/s41467-018-06231-z;

Story Jovanova O, Nedeljkovic I, Spieler D, Walker RM, Liu C, Luciano M, Bressler J, Brody J, Drake AJ, Evans KL, Gondalia R, Kunze S, Kuhnel B, Lahti J, Lemaitre RN, Marioni RE, Swenson B, Himali JJ, Wu H, Li Y, McRae AF, Russ TC, Stewart J, Wang Z, Zhang G, Ladwig KH, Uitterlinden AG, Guo X, Peters A, Räikkönen K, Starr JM, Waldenberger M, Wray NR, Whitsel EA, Sotoodehnia N, Seshadri S, Porteous DJ, van Meurs J, Mosley TH, McIntosh AM, Mendelson MM, Levy D, Hou L, Eriksson JG, Fornage M, Deary IJ, Baccarelli A, Tiemeier H, Amin N. DNA Methylation Signatures of Depressive Symptoms in Middle-aged and Elderly Persons: Meta-analysis of Multiethnic Epigenome-wide Studies. JAMA Psychiatry. 2018 09 01; 75(9):949-959.View Related Profiles.

Liu, Chunyu
Himali, Jayandra
Seshadri, Sudha

PMID: 29998287; PMCID: PMC6142917; DOI: 10.1001/jamapsychiatry.2018.1725;

Yao C, Chen G, Song C, Keefe J, Mendelson M, Huan T, Sun BB, Laser A, Maranville JC, Wu H, Ho JE, Courchesne P, Lyass A, Larson MG, Gieger C, Graumann J, Johnson AD, Danesh J, Runz H, Hwang SJ, Liu C, Butterworth AS, Suhre K, Levy D. Genome-wide mapping of plasma protein QTLs identifies putatively causal genes and pathways for cardiovascular disease. Nat Commun. 2018 08 15; 9(1):3268.View Related Profiles.

Liu, Chunyu
Levy, Daniel
Larson, Martin
Hwang, Shih-Jen

PMID: 30111768; PMCID: PMC6093935; DOI: 10.1038/s41467-018-05512-x;

Ward-Caviness CK, Huffman JE, Everett K, Germain M, van Dongen J, Hill WD, Jhun MA, Brody JA, Ghanbari M, Du L, Roetker NS, de Vries PS, Waldenberger M, Gieger C, Wolf P, Prokisch H, Koenig W, O'Donnell CJ, Levy D, Liu C, Truong V, Wells PS, Trégouët DA, Tang W, Morrison AC, Boerwinkle E, Wiggins KL, McKnight B, Guo X, Psaty BM, Sotoodenia N, Boomsma DI, Willemsen G, Ligthart L, Deary IJ, Zhao W, Ware EB, Kardia SLR, Van Meurs JBJ, Uitterlinden AG, Franco OH, Eriksson P, Franco-Cereceda A, Pankow JS, Johnson AD, Gagnon F, Morange PE, de Geus EJC, Starr JM, Smith JA, Dehghan A, Björck HM, Smith NL, Peters A. DNA methylation age is associated with an altered hemostatic profile in a multiethnic meta-analysis. Blood. 2018 10 25; 132(17):1842-1850.View Related Profiles.

O'Donnell, Christopher
Liu, Chunyu

PMID: 30042098; PMCID: PMC6202911; DOI: 10.1182/blood-2018-02-831347;

Ho JE, Lyass A, Courchesne P, Chen G, Liu C, Yin X, Hwang SJ, Massaro JM, Larson MG, Levy D. Protein Biomarkers of Cardiovascular Disease and Mortality in the Community. J Am Heart Assoc. 2018 07 13; 7(14).View Related Profiles.

Liu, Chunyu
Massaro, Joseph
Larson, Martin
Hwang, Shih-Jen

PMID: 30006491; PMCID: PMC6064847; DOI: 10.1161/JAHA.117.008108;

Aslibekyan S, Agha G, Colicino E, Do AN, Lahti J, Ligthart S, Marioni RE, Marzi C, Mendelson MM, Tanaka T, Wielscher M, Absher DM, Ferrucci L, Franco OH, Gieger C, Grallert H, Hernandez D, Huan T, Iurato S, Joehanes R, Just AC, Kunze S, Lin H, Liu C, Meigs JB, van Meurs JBJ, Moore AZ, Peters A, Prokisch H, Räikkönen K, Rathmann W, Roden M, Schramm K, Schwartz JD, Starr JM, Uitterlinden AG, Vokonas P, Waldenberger M, Yao C, Zhi D, Baccarelli AA, Bandinelli S, Deary IJ, Dehghan A, Eriksson J, Herder C, Jarvelin MR, Levy D, Arnett DK. Association of Methylation Signals With Incident Coronary Heart Disease in an Epigenome-Wide Assessment of Circulating Tumor Necrosis Factor a. JAMA Cardiol. 2018 06 01; 3(6):463-472.View Related Profiles.

Liu, Chunyu
Lin, Honghuang
Vokonas, Pantel

PMID: 29617535; PMCID: PMC6100733; DOI: 10.1001/jamacardio.2018.0510;

Mendelson MM, Johannes R, Liu C, Huan T, Yao C, Miao X, Murabito JM, Dupuis J, Levy D, Benjamin EJ, Lin H. Epigenome-Wide Association Study of Soluble Tumor Necrosis Factor Receptor 2 Levels in the Framingham Heart Study. Front Pharmacol. 2018; 9:207.View Related Profiles.

Liu, Chunyu
Benjamin, Emelia
Lin, Honghuang
Murabito, Joanne
Dupuis, Josee

PMID: 29740313; PMCID: PMC5928448; DOI: 10.3389/fphar.2018.00207;

Ma J, Hennein R, Liu C, Long MT, Hoffmann U, Jacques PF, Lichtenstein AH, Hu FB, Levy D. Improved Diet Quality Associates With Reduction in Liver Fat, Particularly in Individuals With High Genetic Risk Scores for Nonalcoholic Fatty Liver Disease. Gastroenterology. 2018 07; 155(1):107-117.View Related Profiles.

Liu, Chunyu
Long, Michelle

PMID: 29604292; PMCID: PMC6035111; DOI: 10.1053/j.gastro.2018.03.038;

Liu C, Fetterman JL, Liu P, Luo Y, Larson MG, Vasan RS, Zhu J, Levy D. Deep sequencing of the mitochondrial genome reveals common heteroplasmic sites in NADH dehydrogenase genes. Hum Genet. 2018 Mar; 137(3):203-213.View Related Profiles.

Liu, Chunyu
Fetterman, Jessica
Larson, Martin

PMID: 29423652; PMCID: PMC6335583; DOI: 10.1007/s00439-018-1873-4;

Marioni RE, McRae AF, Bressler J, Colicino E, Hannon E, Li S, Prada D, Smith JA, Trevisi L, Tsai PC, Vojinovic D, Simino J, Levy D, Liu C, Mendelson M, Satizabal CL, Yang Q, Jhun MA, Kardia SLR, Zhao W, Bandinelli S, Ferrucci L, Hernandez DG, Singleton AB, Harris SE, Starr JM, Kiel DP, McLean RR, Just AC, Schwartz J, Spiro A, Vokonas P, Amin N, Ikram MA, Uitterlinden AG, van Meurs JBJ, Spector TD, Steves C, Baccarelli AA, Bell JT, van Duijn CM, Fornage M, Hsu YH, Mill J, Mosley TH, Seshadri S, Deary IJ. Meta-analysis of epigenome-wide association studies of cognitive abilities. Mol Psychiatry. 2018 11; 23(11):2133-2144.View Related Profiles.

Spiro, Avron
Liu, Chunyu
Satizabal, Claudia
Vokonas, Pantel
Yang, Qiong
Seshadri, Sudha

PMID: 29311653; PMCID: PMC6035894; DOI: 10.1038/s41380-017-0008-y;

Montalvo-Ortiz JL, Zhang H, Chen C, Liu C, Coccaro EF. Genome-Wide DNA Methylation Changes Associated with Intermittent Explosive Disorder: A Gene-Based Functional Enrichment Analysis. Int J Neuropsychopharmacol. 2018 01 01; 21(1):12-20.View Related Profiles.

Liu, Chunyu
Zhang, Huiping

PMID: 29106553; PMCID: PMC5789263; DOI: 10.1093/ijnp/pyx087;

Richard MA, Huan T, Ligthart S, Gondalia R, Jhun MA, Brody JA, Irvin MR, Marioni R, Shen J, Tsai PC, Montasser ME, Jia Y, Syme C, Salfati EL, Boerwinkle E, Guan W, Mosley TH, Bressler J, Morrison AC, Liu C, Mendelson MM, Uitterlinden AG, van Meurs JB, Franco OH, Zhang G, Li Y, Stewart JD, Bis JC, Psaty BM, Chen YI, Kardia SLR, Zhao W, Turner ST, Absher D, Aslibekyan S, Starr JM, McRae AF, Hou L, Just AC, Schwartz JD, Vokonas PS, Menni C, Spector TD, Shuldiner A, Damcott CM, Rotter JI, Palmas W, Liu Y, Paus T, Horvath S, O'Connell JR, Guo X, Pausova Z, Assimes TL, Sotoodehnia N, Smith JA, Arnett DK, Deary IJ, Baccarelli AA, Bell JT, Whitsel E, Dehghan A, Levy D, Fornage M. DNA Methylation Analysis Identifies Loci for Blood Pressure Regulation. Am J Hum Genet. 2017 Dec 07; 101(6):888-902.View Related Profiles.

Liu, Chunyu
Vokonas, Pantel

PMID: 29198723; PMCID: PMC5812919; DOI: 10.1016/j.ajhg.2017.09.028;

Sharp GC, Arathimos R, Reese SE, Page CM, Felix J, Küpers LK, Rifas-Shiman SL, Liu C, Burrows K, Zhao S, Magnus MC, Duijts L, Corpeleijn E, DeMeo DL, Litonjua A, Baccarelli A, Hivert MF, Oken E, Snieder H, Jaddoe V, Nystad W, London SJ, Relton CL, Zuccolo L. Maternal alcohol consumption and offspring DNA methylation: findings from six general population-based birth cohorts. Epigenomics. 2018 01; 10(1):27-42. PMID: 29172695; PMCID: PMC5753623; DOI: 10.2217/epi-2017-0095;

Chu AY, Tin A, Schlosser P, Ko YA, Qiu C, Yao C, Joehanes R, Grams ME, Liang L, Gluck CA, Liu C, Coresh J, Hwang SJ, Levy D, Boerwinkle E, Pankow JS, Yang Q, Fornage M, Fox CS, Susztak K, Köttgen A. Epigenome-wide association studies identify DNA methylation associated with kidney function. Nat Commun. 2017 11 03; 8(1):1286.View Related Profiles.

Liu, Chunyu
Yang, Qiong
Hwang, Shih-Jen

PMID: 29097680; PMCID: PMC5668367; DOI: 10.1038/s41467-017-01297-7;

Mandaviya PR, Joehanes R, Aïssi D, Kühnel B, Marioni RE, Truong V, Stolk L, Beekman M, Bonder MJ, Franke L, Gieger C, Huan T, Ikram MA, Kunze S, Liang L, Lindemans J, Liu C, McRae AF, Mendelson MM, Müller-Nurasyid M, Peters A, Slagboom PE, Starr JM, Trégouët DA, Uitterlinden AG, van Greevenbroek MMJ, van Heemst D, van Iterson M, Wells PS, Yao C, Deary IJ, Gagnon F, Heijmans BT, Levy D, Morange PE, Waldenberger M, Heil SG, van Meurs JBJ. Genetically defined elevated homocysteine levels do not result in widespread changes of DNA methylation in leukocytes. PLoS One. 2017; 12(10):e0182472. PMID: 29084233; PMCID: PMC5662081; DOI: 10.1371/journal.pone.0182472;

van der Spek A, Luik AI, Kocevska D, Liu C, Brouwer RWW, van Rooij JGJ, van den Hout MCGN, Kraaij R, Hofman A, Uitterlinden AG, van IJcken WFJ, Gottlieb DJ, Tiemeier H, van Duijn CM, Amin N. Exome-Wide Meta-Analysis Identifies Rare 3'-UTR Variant in ERCC1/CD3EAP Associated with Symptoms of Sleep Apnea. Front Genet. 2017; 8:151. PMID: 29093733; PMCID: PMC5651235; DOI: 10.3389/fgene.2017.00151;

Huan T, Chen G, Liu C, Bhattacharya A, Rong J, Chen BH, Seshadri S, Tanriverdi K, Freedman JE, Larson MG, Murabito JM, Levy D. Age-associated microRNA expression in human peripheral blood is associated with all-cause mortality and age-related traits. Aging Cell. 2018 02; 17(1).View Related Profiles.

Liu, Chunyu
Murabito, Joanne
Larson, Martin
Seshadri, Sudha

PMID: 29044988; PMCID: PMC5770777; DOI: 10.1111/acel.12687;

Fetterman JL, Liu C, Mitchell GF, Vasan RS, Benjamin EJ, Vita JA, Hamburg NM, Levy D. Relations of mitochondrial genetic variants to measures of vascular function. Mitochondrion. 2018 05; 40:51-57.View Related Profiles.

Liu, Chunyu
Levy, Daniel
Benjamin, Emelia
Fetterman, Jessica
Hamburg, Naomi
Ramachandran, Vasan

PMID: 28993255; PMCID: PMC5858959; DOI: 10.1016/j.mito.2017.10.001;

Kraja AT, Cook JP, Warren HR, Surendran P, Liu C, Evangelou E, Manning AK, Grarup N, Drenos F, Sim X, Smith AV, Amin N, Blakemore AIF, Bork-Jensen J, Brandslund I, Farmaki AE, Fava C, Ferreira T, Herzig KH, Giri A, Giulianini F, Grove ML, Guo X, Harris SE, Have CT, Havulinna AS, Zhang H, Jørgensen ME, Käräjämäki A, Kooperberg C, Linneberg A, Little L, Liu Y, Bonnycastle LL, Lu Y, Mägi R, Mahajan A, Malerba G, Marioni RE, Mei H, Menni C, Morrison AC, Padmanabhan S, Palmas W, Poveda A, Rauramaa R, Rayner NW, Riaz M, Rice K, Richard MA, Smith JA, Southam L, Stancáková A, Stirrups KE, Tragante V, Tuomi T, Tzoulaki I, Varga TV, Weiss S, Yiorkas AM, Young R, Zhang W, Barnes MR, Cabrera CP, Gao H, Boehnke M, Boerwinkle E, Chambers JC, Connell JM, Christensen CK, de Boer RA, Deary IJ, Dedoussis G, Deloukas P, Dominiczak AF, Dörr M, Joehanes R, Edwards TL, Esko T, Fornage M, Franceschini N, Franks PW, Gambaro G, Groop L, Hallmans G, Hansen T, Hayward C, Heikki O, Ingelsson E, Tuomilehto J, Jarvelin MR, Kardia SLR, Karpe F, Kooner JS, Lakka TA, Langenberg C, Lind L, Loos RJF, Laakso M, McCarthy MI, Melander O, Mohlke KL, Morris AP, Palmer CNA, Pedersen O, Polasek O, Poulter NR, Province MA, Psaty BM, Ridker PM, Rotter JI, Rudan I, Salomaa V, Samani NJ, Sever PJ, Skaaby T, Stafford JM, Starr JM, van der Harst P, van der Meer P, van Duijn CM, Vergnaud AC, Gudnason V, Wareham NJ, Wilson JG, Willer CJ, Witte DR, Zeggini E, Saleheen D, Butterworth AS, Danesh J, Asselbergs FW, Wain LV, Ehret GB, Chasman DI, Caulfield MJ, Elliott P, Lindgren CM, Levy D, Newton-Cheh C, Munroe PB, Howson JMM. New Blood Pressure-Associated Loci Identified in Meta-Analyses of 475?000 Individuals. Circ Cardiovasc Genet. 2017 Oct; 10(5). PMID: 29030403; PMCID: PMC5776077; DOI: 10.1161/CIRCGENETICS.117.001778;

Warren HR, Evangelou E, Cabrera CP, Gao H, Ren M, Mifsud B, Ntalla I, Surendran P, Liu C, Cook JP, Kraja AT, Drenos F, Loh M, Verweij N, Marten J, Karaman I, Segura Lepe MP, O'Reilly PF, Knight J, Snieder H, Kato N, He J, Tai ES, Said MA, Porteous D, Alver M, Poulter N, Farrall M, Gansevoort RT, Padmanabhan S, Mägi R, Stanton A, Connell J, Bakker SJL, Metspalu A, Shields DC, Thom S, Brown M, Sever P, Esko T, Hayward C, van der Harst P, Saleheen D, Chowdhury R, Chambers JC, Chasman DI, Chakravarti A, Newton-Cheh C, Lindgren CM, Levy D, Kooner JS, Keavney B, Tomaszewski M, Samani NJ, Howson JMM, Tobin MD, Munroe PB, Ehret GB, Wain LV, Barnes MR, Tzoulaki I, Caulfield MJ, Elliott P. Corrigendum: Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk. Nat Genet. 2017 09 27; 49(10):1558. PMID: 28951623; DOI: 10.1038/ng1017-1558a;

Yao C, Joehanes R, Johnson AD, Huan T, Liu C, Freedman JE, Munson PJ, Hill DE, Vidal M, Levy D. Dynamic Role of trans Regulation of Gene Expression in Relation to Complex Traits. Am J Hum Genet. 2017 Apr 06; 100(4):571-580. PMID: 28285768; PMCID: PMC5384035; DOI: 10.1016/j.ajhg.2017.02.003;

Warren HR, Evangelou E, Cabrera CP, Gao H, Ren M, Mifsud B, Ntalla I, Surendran P, Liu C, Cook JP, Kraja AT, Drenos F, Loh M, Verweij N, Marten J, Karaman I, Lepe MP, O'Reilly PF, Knight J, Snieder H, Kato N, He J, Tai ES, Said MA, Porteous D, Alver M, Poulter N, Farrall M, Gansevoort RT, Padmanabhan S, Mägi R, Stanton A, Connell J, Bakker SJ, Metspalu A, Shields DC, Thom S, Brown M, Sever P, Esko T, Hayward C, van der Harst P, Saleheen D, Chowdhury R, Chambers JC, Chasman DI, Chakravarti A, Newton-Cheh C, Lindgren CM, Levy D, Kooner JS, Keavney B, Tomaszewski M, Samani NJ, Howson JM, Tobin MD, Munroe PB, Ehret GB, Wain LV. Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk. Nat Genet. 2017 Mar; 49(3):403-415. PMID: 28135244; PMCID: PMC5972004; DOI: 10.1038/ng.3768;

Mendelson MM, Marioni RE, Joehanes R, Liu C, Hedman ÅK, Aslibekyan S, Demerath EW, Guan W, Zhi D, Yao C, Huan T, Willinger C, Chen B, Courchesne P, Multhaup M, Irvin MR, Cohain A, Schadt EE, Grove ML, Bressler J, North K, Sundström J, Gustafsson S, Shah S, McRae AF, Harris SE, Gibson J, Redmond P, Corley J, Murphy L, Starr JM, Kleinbrink E, Lipovich L, Visscher PM, Wray NR, Krauss RM, Fallin D, Feinberg A, Absher DM, Fornage M, Pankow JS, Lind L, Fox C, Ingelsson E, Arnett DK, Boerwinkle E, Liang L, Levy D, Deary IJ. Association of Body Mass Index with DNA Methylation and Gene Expression in Blood Cells and Relations to Cardiometabolic Disease: A Mendelian Randomization Approach. PLoS Med. 2017 Jan; 14(1):e1002215. PMID: 28095459; PMCID: PMC5240936; DOI: 10.1371/journal.pmed.1002215;

Lin H, Yin X, Xie Z, Lunetta KL, Lubitz SA, Larson MG, Ko D, Magnani JW, Mendelson MM, Liu C, McManus DD, Levy D, Ellinor PT, Benjamin EJ. Methylome-wide Association Study of Atrial Fibrillation in Framingham Heart Study. Sci Rep. 2017 01 09; 7:40377.View Related Profiles.

Liu, Chunyu
Ko, Darae
Benjamin, Emelia
Lin, Honghuang
Lunetta, Kathryn
Larson, Martin

PMID: 28067321; PMCID: PMC5220313; DOI: 10.1038/srep40377;

Hedman ÅK, Mendelson MM, Marioni RE, Gustafsson S, Joehanes R, Irvin MR, Zhi D, Sandling JK, Yao C, Liu C, Liang L, Huan T, McRae AF, Demissie S, Shah S, Starr JM, Cupples LA, Deloukas P, Spector TD, Sundström J, Krauss RM, Arnett DK, Deary IJ, Lind L, Levy D, Ingelsson E. Epigenetic Patterns in Blood Associated With Lipid Traits Predict Incident Coronary Heart Disease Events and Are Enriched for Results From Genome-Wide Association Studies. Circ Cardiovasc Genet. 2017 Jan; 10(1).View Related Profiles.

Liu, Chunyu
Cupples, L
Demissie, Serkalem

PMID: 28213390; PMCID: PMC5331877; DOI: 10.1161/CIRCGENETICS.116.001487;

Ligthart S, Marzi C, Aslibekyan S, Mendelson MM, Conneely KN, Tanaka T, Colicino E, Waite LL, Joehanes R, Guan W, Brody JA, Elks C, Marioni R, Jhun MA, Agha G, Bressler J, Ward-Caviness CK, Chen BH, Huan T, Bakulski K, Salfati EL, Fiorito G, Wahl S, Schramm K, Sha J, Hernandez DG, Just AC, Smith JA, Sotoodehnia N, Pilling LC, Pankow JS, Tsao PS, Liu C, Zhao W, Guarrera S, Michopoulos VJ, Smith AK, Peters MJ, Melzer D, Vokonas P, Fornage M, Prokisch H, Bis JC, Chu AY, Herder C, Grallert H, Yao C, Shah S, McRae AF, Lin H, Horvath S, Fallin D, Hofman A, Wareham NJ, Wiggins KL, Feinberg AP, Starr JM, Visscher PM, Murabito JM, Kardia SL, Absher DM, Binder EB, Singleton AB, Bandinelli S, Peters A, Waldenberger M, Matullo G, Schwartz JD, Demerath EW, Uitterlinden AG, van Meurs JB, Franco OH, Chen YI, Levy D, Turner ST, Deary IJ, Ressler KJ, Dupuis J, Ferrucci L, Ong KK, Assimes TL, Boerwinkle E, Koenig W, Arnett DK, Baccarelli AA, Benjamin EJ, Dehghan A. DNA methylation signatures of chronic low-grade inflammation are associated with complex diseases. Genome Biol. 2016 Dec 12; 17(1):255.View Related Profiles.

Liu, Chunyu
Benjamin, Emelia
Lin, Honghuang
Murabito, Joanne
Dupuis, Josee
Vokonas, Pantel

PMID: 27955697; PMCID: PMC5151130; DOI: 10.1186/s13059-016-1119-5;

Li M, Li Y, Weeks O, Mijatovic V, Teumer A, Huffman JE, Tromp G, Fuchsberger C, Gorski M, Lyytikäinen LP, Nutile T, Sedaghat S, Sorice R, Tin A, Yang Q, Ahluwalia TS, Arking DE, Bihlmeyer NA, Böger CA, Carroll RJ, Chasman DI, Cornelis MC, Dehghan A, Faul JD, Feitosa MF, Gambaro G, Gasparini P, Giulianini F, Heid I, Huang J, Imboden M, Jackson AU, Jeff J, Jhun MA, Katz R, Kifley A, Kilpeläinen TO, Kumar A, Laakso M, Li-Gao R, Lohman K, Lu Y, Mägi R, Malerba G, Mihailov E, Mohlke KL, Mook-Kanamori DO, Robino A, Ruderfer D, Salvi E, Schick UM, Schulz CA, Smith AV, Smith JA, Traglia M, Yerges-Armstrong LM, Zhao W, Goodarzi MO, Kraja AT, Liu C, Wessel J, Boerwinkle E, Borecki IB, Bork-Jensen J, Bottinger EP, Braga D, Brandslund I, Brody JA, Campbell A, Carey DJ, Christensen C, Coresh J, Crook E, Curhan GC, Cusi D, de Boer IH, de Vries AP, Denny JC, Devuyst O, Dreisbach AW, Endlich K, Esko T, Franco OH, Fulop T, Gerhard GS, Glümer C, Gottesman O, Grarup N, Gudnason V, Hansen T, Harris TB, Hayward C, Hocking L, Hofman A, Hu FB, Husemoen LL, Jackson RD, Jørgensen T, Jørgensen ME, Kähönen M, Kardia SL, König W, Kooperberg C, Kriebel J, Launer LJ, Lauritzen T, Lehtimäki T, Levy D, Linksted P, Linneberg A, Liu Y, Loos RJ, Lupo A, Meisinger C, Melander O, Metspalu A, Mitchell P, Nauck M, Nürnberg P, Orho-Melander M, Parsa A, Pedersen O, Peters A, Peters U, Polasek O, Porteous D, Probst-Hensch NM, Psaty BM, Qi L, Raitakari OT, Reiner AP, Rettig R, Ridker PM, Rivadeneira F, Rossouw JE, Schmidt F, Siscovick D, Soranzo N, Strauch K, Toniolo D, Turner ST, Uitterlinden AG, Ulivi S, Velayutham D, Völker U, Völzke H, Waldenberger M, Wang JJ, Weir DR, Witte D, Kuivaniemi H, Fox CS, Franceschini N, Goessling W, Köttgen A, Chu AY. SOS2 and ACP1 Loci Identified through Large-Scale Exome Chip Analysis Regulate Kidney Development and Function. J Am Soc Nephrol. 2017 Mar; 28(3):981-994.View Related Profiles.

Liu, Chunyu
Cupples, L
Yang, Qiong
Ramachandran, Vasan

PMID: 27920155; PMCID: PMC5328154; DOI: 10.1681/ASN.2016020131;

Schumann G, Liu C, O'Reilly P, Gao H, Song P, Xu B, Ruggeri B, Amin N, Jia T, Preis S, Segura Lepe M, Akira S, Barbieri C, Baumeister S, Cauchi S, Clarke TK, Enroth S, Fischer K, Hällfors J, Harris SE, Hieber S, Hofer E, Hottenga JJ, Johansson Å, Joshi PK, Kaartinen N, Laitinen J, Lemaitre R, Loukola A, Luan J, Lyytikäinen LP, Mangino M, Manichaikul A, Mbarek H, Milaneschi Y, Moayyeri A, Mukamal K, Nelson C, Nettleton J, Partinen E, Rawal R, Robino A, Rose L, Sala C, Satoh T, Schmidt R, Schraut K, Scott R, Smith AV, Starr JM, Teumer A, Trompet S, Uitterlinden AG, Venturini C, Vergnaud AC, Verweij N, Vitart V, Vuckovic D, Wedenoja J, Yengo L, Yu B, Zhang W, Zhao JH, Boomsma DI, Chambers J, Chasman DI, Daniela T, de Geus E, Deary I, Eriksson JG, Esko T, Eulenburg V, Franco OH, Froguel P, Gieger C, Grabe HJ, Gudnason V, Gyllensten U, Harris TB, Hartikainen AL, Heath AC, Hocking L, Hofman A, Huth C, Jarvelin MR, Jukema JW, Kaprio J, Kooner JS, Kutalik Z, Lahti J, Langenberg C, Lehtimäki T, Liu Y, Madden PA, Martin N, Morrison A, Penninx B, Pirastu N, Psaty B, Raitakari O, Ridker P, Rose R, Rotter JI, Samani NJ, Schmidt H, Spector TD, Stott D, Strachan D, Tzoulaki I, van der Harst P, van Duijn CM, Marques-Vidal P, Vollenweider P, Wareham NJ, Whitfield JB, Wilson J, Wolffenbuttel B, Bakalkin G, Evangelou E, Liu Y, Rice KM, Desrivières S, Kliewer SA, Mangelsdorf DJ, Müller CP, Levy D, Elliott P. KLB is associated with alcohol drinking, and its gene product ß-Klotho is necessary for FGF21 regulation of alcohol preference. Proc Natl Acad Sci U S A. 2016 12 13; 113(50):14372-14377.View Related Profiles.

Liu, Chunyu
Preis, Sarah

PMID: 27911795; PMCID: PMC5167198; DOI: 10.1073/pnas.1611243113;

Liu C, Marioni RE, Hedman ÅK, Pfeiffer L, Tsai PC, Reynolds LM, Just AC, Duan Q, Boer CG, Tanaka T, Elks CE, Aslibekyan S, Brody JA, Kühnel B, Herder C, Almli LM, Zhi D, Wang Y, Huan T, Yao C, Mendelson MM, Joehanes R, Liang L, Love SA, Guan W, Shah S, McRae AF, Kretschmer A, Prokisch H, Strauch K, Peters A, Visscher PM, Wray NR, Guo X, Wiggins KL, Smith AK, Binder EB, Ressler KJ, Irvin MR, Absher DM, Hernandez D, Ferrucci L, Bandinelli S, Lohman K, Ding J, Trevisi L, Gustafsson S, Sandling JH, Stolk L, Uitterlinden AG, Yet I, Castillo-Fernandez JE, Spector TD, Schwartz JD, Vokonas P, Lind L, Li Y, Fornage M, Arnett DK, Wareham NJ, Sotoodehnia N, Ong KK, van Meurs JBJ, Conneely KN, Baccarelli AA, Deary IJ, Bell JT, North KE, Liu Y, Waldenberger M, London SJ, Ingelsson E, Levy D. A DNA methylation biomarker of alcohol consumption. Mol Psychiatry. 2018 02; 23(2):422-433.View Related Profiles.

Liu, Chunyu
Vokonas, Pantel

PMID: 27843151; PMCID: PMC5575985; DOI: 10.1038/mp.2016.192;

Joehanes R, Just AC, Marioni RE, Pilling LC, Reynolds LM, Mandaviya PR, Guan W, Xu T, Elks CE, Aslibekyan S, Moreno-Macias H, Smith JA, Brody JA, Dhingra R, Yousefi P, Pankow JS, Kunze S, Shah SH, McRae AF, Lohman K, Sha J, Absher DM, Ferrucci L, Zhao W, Demerath EW, Bressler J, Grove ML, Huan T, Liu C, Mendelson MM, Yao C, Kiel DP, Peters A, Wang-Sattler R, Visscher PM, Wray NR, Starr JM, Ding J, Rodriguez CJ, Wareham NJ, Irvin MR, Zhi D, Barrdahl M, Vineis P, Ambatipudi S, Uitterlinden AG, Hofman A, Schwartz J, Colicino E, Hou L, Vokonas PS, Hernandez DG, Singleton AB, Bandinelli S, Turner ST, Ware EB, Smith AK, Klengel T, Binder EB, Psaty BM, Taylor KD, Gharib SA, Swenson BR, Liang L, DeMeo DL, O'Connor GT, Herceg Z, Ressler KJ, Conneely KN, Sotoodehnia N, Kardia SL, Melzer D, Baccarelli AA, van Meurs JB, Romieu I, Arnett DK, Ong KK, Liu Y, Waldenberger M, Deary IJ, Fornage M, Levy D, London SJ. Epigenetic Signatures of Cigarette Smoking. Circ Cardiovasc Genet. 2016 Oct; 9(5):436-447.View Related Profiles.

Liu, Chunyu
O'Connor, George
Vokonas, Pantel

PMID: 27651444; PMCID: PMC5267325; DOI: 10.1161/CIRCGENETICS.116.001506;

Surendran P, Drenos F, Young R, Warren H, Cook JP, Manning AK, Grarup N, Sim X, Barnes DR, Witkowska K, Staley JR, Tragante V, Tukiainen T, Yaghootkar H, Masca N, Freitag DF, Ferreira T, Giannakopoulou O, Tinker A, Harakalova M, Mihailov E, Liu C, Kraja AT, Nielsen SF, Rasheed A, Samuel M, Zhao W, Bonnycastle LL, Jackson AU, Narisu N, Swift AJ, Southam L, Marten J, Huyghe JR, Stancáková A, Fava C, Ohlsson T, Matchan A, Stirrups KE, Bork-Jensen J, Gjesing AP, Kontto J, Perola M, Shaw-Hawkins S, Havulinna AS, Zhang H, Donnelly LA, Groves CJ, Rayner NW, Neville MJ, Robertson NR, Yiorkas AM, Herzig KH, Kajantie E, Zhang W, Willems SM, Lannfelt L, Malerba G, Soranzo N, Trabetti E, Verweij N, Evangelou E, Moayyeri A, Vergnaud AC, Nelson CP, Poveda A, Varga TV, Caslake M, de Craen AJ, Trompet S, Luan J, Scott RA, Harris SE, Liewald DC, Marioni R, Menni C, Farmaki AE, Hallmans G, Renström F, Huffman JE, Hassinen M, Burgess S, Vasan RS, Felix JF, Uria-Nickelsen M, Malarstig A, Reilly DF, Hoek M, Vogt TF, Lin H, Lieb W, Traylor M, Markus HS, Highland HM, Justice AE, Marouli E, Lindström J, Uusitupa M, Komulainen P, Lakka TA, Rauramaa R, Polasek O, Rudan I, Rolandsson O, Franks PW, Dedoussis G, Spector TD, Jousilahti P, Männistö S, Deary IJ, Starr JM, Langenberg C, Wareham NJ, Brown MJ, Dominiczak AF, Connell JM, Jukema JW, Sattar N, Ford I, Packard CJ, Esko T, Mägi R, Metspalu A, de Boer RA, van der Meer P, van der Harst P, Gambaro G, Ingelsson E, Lind L, de Bakker PI, Numans ME, Brandslund I, Christensen C, Petersen ER, Korpi-Hyövälti E, Oksa H, Chambers JC, Kooner JS, Blakemore AI, Franks S, Jarvelin MR, Husemoen LL, Linneberg A, Skaaby T, Thuesen B, Karpe F, Tuomilehto J, Doney AS, Morris AD, Palmer CN, Holmen OL, Hveem K, Willer CJ, Tuomi T, Groop L, Käräjämäki A, Palotie A, Ripatti S, Salomaa V, Alam DS, Majumder AA, Di Angelantonio E, Chowdhury R, McCarthy MI, Poulter N, Stanton AV, Sever P, Amouyel P, Arveiler D, Blankenberg S, Ferrières J, Kee F, Kuulasmaa K, Müller-Nurasyid M, Veronesi G, Virtamo J, Deloukas P, Elliott P, Zeggini E, Kathiresan S, Melander O, Kuusisto J, Laakso M, Padmanabhan S, Porteous DJ, Hayward C, Scotland G, Collins FS, Mohlke KL, Hansen T, Pedersen O, Boehnke M, Stringham HM, Frossard P, Newton-Cheh C, Tobin MD, Nordestgaard BG, Caulfield MJ, Mahajan A, Morris AP, Tomaszewski M, Samani NJ, Saleheen D, Asselbergs FW, Lindgren CM, Danesh J, Wain LV, Butterworth AS, Howson JM, Munroe PB. Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension. Nat Genet. 2016 Oct; 48(10):1151-61.View Related Profiles.

Liu, Chunyu
Lin, Honghuang
Ramachandran, Vasan

PMID: 27618447; PMCID: PMC5056636; DOI: 10.1038/ng.3654;

Liu C, Kraja AT, Smith JA, Brody JA, Franceschini N, Bis JC, Rice K, Morrison AC, Lu Y, Weiss S, Guo X, Palmas W, Martin LW, Chen YD, Surendran P, Drenos F, Cook JP, Auer PL, Chu AY, Giri A, Zhao W, Jakobsdottir J, Lin LA, Stafford JM, Amin N, Mei H, Yao J, Voorman A, Larson MG, Grove ML, Smith AV, Hwang SJ, Chen H, Huan T, Kosova G, Stitziel NO, Kathiresan S, Samani N, Schunkert H, Deloukas P, Li M, Fuchsberger C, Pattaro C, Gorski M, Kooperberg C, Papanicolaou GJ, Rossouw JE, Faul JD, Kardia SL, Bouchard C, Raffel LJ, Uitterlinden AG, Franco OH, Vasan RS, O'Donnell CJ, Taylor KD, Liu K, Bottinger EP, Gottesman O, Daw EW, Giulianini F, Ganesh S, Salfati E, Harris TB, Launer LJ, Dörr M, Felix SB, Rettig R, Völzke H, Kim E, Lee WJ, Lee IT, Sheu WH, Tsosie KS, Edwards DR, Liu Y, Correa A, Weir DR, Völker U, Ridker PM, Boerwinkle E, Gudnason V, Reiner AP, van Duijn CM, Borecki IB, Edwards TL, Chakravarti A, Rotter JI, Psaty BM, Loos RJ, Fornage M, Ehret GB, Newton-Cheh C, Levy D, Chasman DI. Meta-analysis identifies common and rare variants influencing blood pressure and overlapping with metabolic trait loci. Nat Genet. 2016 Oct; 48(10):1162-70.View Related Profiles.

O'Donnell, Christopher
Liu, Chunyu
Larson, Martin
Hwang, Shih-Jen
Ramachandran, Vasan

PMID: 27618448; PMCID: PMC5320952; DOI: 10.1038/ng.3660;

Scott RA, Freitag DF, Li L, Chu AY, Surendran P, Young R, Grarup N, Stancáková A, Chen Y, Varga TV, Yaghootkar H, Luan J, Zhao JH, Willems SM, Wessel J, Wang S, Maruthur N, Michailidou K, Pirie A, van der Lee SJ, Gillson C, Al Olama AA, Amouyel P, Arriola L, Arveiler D, Aviles-Olmos I, Balkau B, Barricarte A, Barroso I, Garcia SB, Bis JC, Blankenberg S, Boehnke M, Boeing H, Boerwinkle E, Borecki IB, Bork-Jensen J, Bowden S, Caldas C, Caslake M, Cupples LA, Cruchaga C, Czajkowski J, den Hoed M, Dunn JA, Earl HM, Ehret GB, Ferrannini E, Ferrieres J, Foltynie T, Ford I, Forouhi NG, Gianfagna F, Gonzalez C, Grioni S, Hiller L, Jansson JH, Jørgensen ME, Jukema JW, Kaaks R, Kee F, Kerrison ND, Key TJ, Kontto J, Kote-Jarai Z, Kraja AT, Kuulasmaa K, Kuusisto J, Linneberg A, Liu C, Marenne G, Mohlke KL, Morris AP, Muir K, Müller-Nurasyid M, Munroe PB, Navarro C, Nielsen SF, Nilsson PM, Nordestgaard BG, Packard CJ, Palli D, Panico S, Peloso GM, Perola M, Peters A, Poole CJ, Quirós JR, Rolandsson O, Sacerdote C, Salomaa V, Sánchez MJ, Sattar N, Sharp SJ, Sims R, Slimani N, Smith JA, Thompson DJ, Trompet S, Tumino R, van der A DL, van der Schouw YT, Virtamo J, Walker M, Walter K, Abraham JE, Amundadottir LT, Aponte JL, Butterworth AS, Dupuis J, Easton DF, Eeles RA, Erdmann J, Franks PW, Frayling TM, Hansen T, Howson JM, Jørgensen T, Kooner J, Laakso M, Langenberg C, McCarthy MI, Pankow JS, Pedersen O, Riboli E, Rotter JI, Saleheen D, Samani NJ, Schunkert H, Vollenweider P, O'Rahilly S, Deloukas P, Danesh J, Goodarzi MO, Kathiresan S, Meigs JB, Ehm MG, Wareham NJ, Waterworth DM. A genomic approach to therapeutic target validation identifies a glucose-lowering GLP1R variant protective for coronary heart disease. Sci Transl Med. 2016 Jun 01; 8(341):341ra76.View Related Profiles.

Liu, Chunyu
Peloso, Gina
Dupuis, Josee
Cupples, L

PMID: 27252175; PMCID: PMC5219001; DOI: 10.1126/scitranslmed.aad3744;

Smith JG, Felix JF, Morrison AC, Kalogeropoulos A, Trompet S, Wilk JB, Gidlöf O, Wang X, Morley M, Mendelson M, Joehanes R, Ligthart S, Shan X, Bis JC, Wang YA, Sjögren M, Ngwa J, Brandimarto J, Stott DJ, Aguilar D, Rice KM, Sesso HD, Demissie S, Buckley BM, Taylor KD, Ford I, Yao C, Liu C, Sotoodehnia N, van der Harst P, Stricker BH, Kritchevsky SB, Liu Y, Gaziano JM, Hofman A, Moravec CS, Uitterlinden AG, Kellis M, van Meurs JB, Margulies KB, Dehghan A, Levy D, Olde B, Psaty BM, Cupples LA, Jukema JW, Djousse L, Franco OH, Boerwinkle E, Boyer LA, Newton-Cheh C, Butler J, Vasan RS, Cappola TP, Smith NL. Discovery of Genetic Variation on Chromosome 5q22 Associated with Mortality in Heart Failure. PLoS Genet. 2016 May; 12(5):e1006034.View Related Profiles.

Liu, Chunyu
Gaziano, J. Michael
Cupples, L
Demissie, Serkalem
Ramachandran, Vasan

PMID: 27149122; PMCID: PMC4858216; DOI: 10.1371/journal.pgen.1006034;

Coding Variation in ANGPTL4, LPL, and SVEP1 and the Risk of Coronary Disease. N Engl J Med. 2016 Mar 24; 374(12):1134-44.View Related Profiles.

Liu, Chunyu
Peloso, Gina

PMID: 26934567; PMCID: PMC4850838; DOI: 10.1056/NEJMoa1507652;

Aslibekyan S, Demerath EW, Mendelson M, Zhi D, Guan W, Liang L, Sha J, Pankow JS, Liu C, Irvin MR, Fornage M, Hidalgo B, Lin LA, Thibeault KS, Bressler J, Tsai MY, Grove ML, Hopkins PN, Boerwinkle E, Borecki IB, Ordovas JM, Levy D, Tiwari HK, Absher DM, Arnett DK. Epigenome-wide study identifies novel methylation loci associated with body mass index and waist circumference. Obesity (Silver Spring). 2015 Jul; 23(7):1493-501. PMID: 26110892; PMCID: PMC4482015; DOI: 10.1002/oby.21111;

Shah S, Bonder MJ, Marioni RE, Zhu Z, McRae AF, Zhernakova A, Harris SE, Liewald D, Henders AK, Mendelson MM, Liu C, Joehanes R, Liang L, Levy D, Martin NG, Starr JM, Wijmenga C, Wray NR, Yang J, Montgomery GW, Franke L, Deary IJ, Visscher PM. Improving Phenotypic Prediction by Combining Genetic and Epigenetic Associations. Am J Hum Genet. 2015 Jul 02; 97(1):75-85. PMID: 26119815; PMCID: PMC4572498; DOI: 10.1016/j.ajhg.2015.05.014;

Demerath EW, Guan W, Grove ML, Aslibekyan S, Mendelson M, Zhou YH, Hedman ÅK, Sandling JK, Li LA, Irvin MR, Zhi D, Deloukas P, Liang L, Liu C, Bressler J, Spector TD, North K, Li Y, Absher DM, Levy D, Arnett DK, Fornage M, Pankow JS, Boerwinkle E. Epigenome-wide association study (EWAS) of BMI, BMI change and waist circumference in African American adults identifies multiple replicated loci. Hum Mol Genet. 2015 Aug 01; 24(15):4464-79. PMID: 25935004; PMCID: PMC4492394; DOI: 10.1093/hmg/ddv161;

Huan T, Rong J, Liu C, Zhang X, Tanriverdi K, Joehanes R, Chen BH, Murabito JM, Yao C, Courchesne P, Munson PJ, O'Donnell CJ, Cox N, Johnson AD, Larson MG, Levy D, Freedman JE. Genome-wide identification of microRNA expression quantitative trait loci. Nat Commun. 2015; 6:6601.View Related Profiles.

O'Donnell, Christopher
Liu, Chunyu
Murabito, Joanne
Larson, Martin
Zhang, Xiaoling

PMID: 25791433; PMCID: PMC4369777; DOI: 10.1038/ncomms7601;

Huan T, Esko T, Peters MJ, Pilling LC, Schramm K, Schurmann C, Chen BH, Liu C, Joehanes R, Johnson AD, Yao C, Ying SX, Courchesne P, Milani L, Raghavachari N, Wang R, Liu P, Reinmaa E, Dehghan A, Hofman A, Uitterlinden AG, Hernandez DG, Bandinelli S, Singleton A, Melzer D, Metspalu A, Carstensen M, Grallert H, Herder C, Meitinger T, Peters A, Roden M, Waldenberger M, Dörr M, Felix SB, Zeller T, Vasan R, O'Donnell CJ, Munson PJ, Yang X, Prokisch H, Völker U, van Meurs JB, Ferrucci L, Levy D. A meta-analysis of gene expression signatures of blood pressure and hypertension. PLoS Genet. 2015 Mar; 11(3):e1005035.View Related Profiles.

O'Donnell, Christopher
Liu, Chunyu
Ramachandran, Vasan

PMID: 25785607; PMCID: PMC4365001; DOI: 10.1371/journal.pgen.1005035;

Wessel J, Chu AY, Willems SM, Wang S, Yaghootkar H, Brody JA, Dauriz M, Hivert MF, Raghavan S, Lipovich L, Hidalgo B, Fox K, Huffman JE, An P, Lu Y, Rasmussen-Torvik LJ, Grarup N, Ehm MG, Li L, Baldridge AS, Stancáková A, Abrol R, Besse C, Boland A, Bork-Jensen J, Fornage M, Freitag DF, Garcia ME, Guo X, Hara K, Isaacs A, Jakobsdottir J, Lange LA, Layton JC, Li M, Hua Zhao J, Meidtner K, Morrison AC, Nalls MA, Peters MJ, Sabater-Lleal M, Schurmann C, Silveira A, Smith AV, Southam L, Stoiber MH, Strawbridge RJ, Taylor KD, Varga TV, Allin KH, Amin N, Aponte JL, Aung T, Barbieri C, Bihlmeyer NA, Boehnke M, Bombieri C, Bowden DW, Burns SM, Chen Y, Chen YD, Cheng CY, Correa A, Czajkowski J, Dehghan A, Ehret GB, Eiriksdottir G, Escher SA, Farmaki AE, Frånberg M, Gambaro G, Giulianini F, Goddard WA, Goel A, Gottesman O, Grove ML, Gustafsson S, Hai Y, Hallmans G, Heo J, Hoffmann P, Ikram MK, Jensen RA, Jørgensen ME, Jørgensen T, Karaleftheri M, Khor CC, Kirkpatrick A, Kraja AT, Kuusisto J, Lange EM, Lee IT, Lee WJ, Leong A, Liao J, Liu C, Liu Y, Lindgren CM, Linneberg A, Malerba G, Mamakou V, Marouli E, Maruthur NM, Matchan A, McKean-Cowdin R, McLeod O, Metcalf GA, Mohlke KL, Muzny DM, Ntalla I, Palmer ND, Pasko D, Peter A, Rayner NW, Renström F, Rice K, Sala CF, Sennblad B, Serafetinidis I, Smith JA, Soranzo N, Speliotes EK, Stahl EA, Stirrups K, Tentolouris N, Thanopoulou A, Torres M, Traglia M, Tsafantakis E, Javad S, Yanek LR, Zengini E, Becker DM, Bis JC, Brown JB, Cupples LA, Hansen T, Ingelsson E, Karter AJ, Lorenzo C, Mathias RA, Norris JM, Peloso GM, Sheu WH, Toniolo D, Vaidya D, Varma R, Wagenknecht LE, Boeing H, Bottinger EP, Dedoussis G, Deloukas P, Ferrannini E, Franco OH, Franks PW, Gibbs RA, Gudnason V, Hamsten A, Harris TB, Hattersley AT, Hayward C, Hofman A, Jansson JH, Langenberg C, Launer LJ, Levy D, Oostra BA, O'Donnell CJ, O'Rahilly S, Padmanabhan S, Pankow JS, Polasek O, Province MA, Rich SS, Ridker PM, Rudan I, Schulze MB, Smith BH, Uitterlinden AG, Walker M, Watkins H, Wong TY, Zeggini E, Laakso M, Borecki IB, Chasman DI, Pedersen O, Psaty BM, Tai ES, van Duijn CM, Wareham NJ, Waterworth DM, Boerwinkle E, Kao WH, Florez JC, Loos RJ, Wilson JG, Frayling TM, Siscovick DS, Dupuis J, Rotter JI, Meigs JB, Scott RA, Goodarzi MO. Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility. Nat Commun. 2015; 6:5897.View Related Profiles.

O'Donnell, Christopher
Liu, Chunyu
Peloso, Gina
Dupuis, Josee
Cupples, L

PMID: 25631608; PMCID: PMC4311266; DOI: 10.1038/ncomms6897;

Huan T, Liu C, Joehanes R, Zhang X, Chen BH, Johnson AD, Yao C, Courchesne P, O'Donnell CJ, Munson PJ, Levy D. A systematic heritability analysis of the human whole blood transcriptome. Hum Genet. 2015 Mar; 134(3):343-58.View Related Profiles.

O'Donnell, Christopher
Liu, Chunyu
Zhang, Xiaoling

PMID: 25585846; PMCID: PMC4339826; DOI: 10.1007/s00439-014-1524-3;

Yao C, Chen BH, Joehanes R, Otlu B, Zhang X, Liu C, Huan T, Tastan O, Cupples LA, Meigs JB, Fox CS, Freedman JE, Courchesne P, O'Donnell CJ, Munson PJ, Keles S, Levy D. Integromic analysis of genetic variation and gene expression identifies networks for cardiovascular disease phenotypes. Circulation. 2015 Feb 10; 131(6):536-49.View Related Profiles.

O'Donnell, Christopher
Liu, Chunyu
Levy, Daniel
Cupples, L
Zhang, Xiaoling

PMID: 25533967; PMCID: PMC4369387; DOI: 10.1161/CIRCULATIONAHA.114.010696;

Liu C, Dupuis J, Larson MG, Cupples LA, Ordovas JM, Vasan RS, Meigs JB, Jacques PF, Levy D. Revisiting heritability accounting for shared environmental effects and maternal inheritance. Hum Genet. 2015 Feb; 134(2):169-79.View Related Profiles.

Liu, Chunyu
Dupuis, Josee
Cupples, L
Larson, Martin
Ramachandran, Vasan

PMID: 25381465; PMCID: PMC4303043; DOI: 10.1007/s00439-014-1505-6;

Subramanian S, Liu C, Aviv A, Ho JE, Courchesne P, Muntendam P, Larson MG, Cheng S, Wang TJ, Mehta NN, Levy D. Stromal cell-derived factor 1 as a biomarker of heart failure and mortality risk. Arterioscler Thromb Vasc Biol. 2014 Sep; 34(9):2100-5.View Related Profiles.

Liu, Chunyu
Levy, Daniel
Ho, Jennifer
Larson, Martin

PMID: 25060794; PMCID: PMC4142677; DOI: 10.1161/ATVBAHA.114.303579;

Porcu E, Medici M, Pistis G, Volpato CB, Wilson SG, Cappola AR, Bos SD, Deelen J, den Heijer M, Freathy RM, Lahti J, Liu C, Lopez LM, Nolte IM, O'Connell JR, Tanaka T, Trompet S, Arnold A, Bandinelli S, Beekman M, Böhringer S, Brown SJ, Buckley BM, Camaschella C, de Craen AJ, Davies G, de Visser MC, Ford I, Forsen T, Frayling TM, Fugazzola L, Gögele M, Hattersley AT, Hermus AR, Hofman A, Houwing-Duistermaat JJ, Jensen RA, Kajantie E, Kloppenburg M, Lim EM, Masciullo C, Mariotti S, Minelli C, Mitchell BD, Nagaraja R, Netea-Maier RT, Palotie A, Persani L, Piras MG, Psaty BM, Räikkönen K, Richards JB, Rivadeneira F, Sala C, Sabra MM, Sattar N, Shields BM, Soranzo N, Starr JM, Stott DJ, Sweep FC, Usala G, van der Klauw MM, van Heemst D, van Mullem A, Vermeulen SH, Visser WE, Walsh JP, Westendorp RG, Widen E, Zhai G, Cucca F, Deary IJ, Eriksson JG, Ferrucci L, Fox CS, Jukema JW, Kiemeney LA, Pramstaller PP, Schlessinger D, Shuldiner AR, Slagboom EP, Uitterlinden AG, Vaidya B, Visser TJ, Wolffenbuttel BH, Meulenbelt I, Rotter JI, Spector TD, Hicks AA, Toniolo D, Sanna S, Peeters RP, Naitza S. A meta-analysis of thyroid-related traits reveals novel loci and gender-specific differences in the regulation of thyroid function. PLoS Genet. 2013; 9(2):e1003266. PMID: 23408906; PMCID: PMC3567175; DOI: 10.1371/journal.pgen.1003266;

Liu C, Dupuis J, Larson MG, Levy D. Association testing of the mitochondrial genome using pedigree data. Genet Epidemiol. 2013 Apr; 37(3):239-47.View Related Profiles.

Liu, Chunyu
Dupuis, Josee
Larson, Martin

PMID: 23319385; PMCID: PMC4171957; DOI: 10.1002/gepi.21706;

Liu C, Yang Q, Hwang SJ, Sun F, Johnson AD, Shirihai OS, Vasan RS, Levy D, Schwartz F. Association of genetic variation in the mitochondrial genome with blood pressure and metabolic traits. Hypertension. 2012 Oct; 60(4):949-56.View Related Profiles.

Liu, Chunyu
Shirihai, Orian
Yang, Qiong
Hwang, Shih-Jen
Ramachandran, Vasan

PMID: 22949535; PMCID: PMC3753106; DOI: 10.1161/HYPERTENSIONAHA.112.196519;

Ho JE, Liu C, Lyass A, Courchesne P, Pencina MJ, Vasan RS, Larson MG, Levy D. Galectin-3, a marker of cardiac fibrosis, predicts incident heart failure in the community. J Am Coll Cardiol. 2012 Oct 2; 60(14):1249-56.View Related Profiles.

Liu, Chunyu
Ho, Jennifer
Larson, Martin
Pencina, Michael
Ramachandran, Vasan

PMID: 22939561; PMCID: PMC3512095; DOI: 10.1016/j.jacc.2012.04.053;

Choi SH, Liu C, Dupuis J, Logue MW, Jun G. Using linkage analysis of large pedigrees to guide association analyses. BMC Proc. 2011; 5 Suppl 9:S79.View Related Profiles.

Liu, Chunyu
Jun, Gyungah
Dupuis, Josee
Logue, Mark
Choi, Seung Hoan

PMID: 22373287; PMCID: PMC3287919; DOI: 10.1186/1753-6561-5-S9-S79;

Liu C, Ackerman HH, Carulli JP. A genome-wide screen of gene-gene interactions for rheumatoid arthritis susceptibility. Hum Genet. 2011 May; 129(5):473-85. PMID: 21210282; DOI: 10.1007/s00439-010-0943-z;

Liu C, Yang Q, Adrienne Cupples L, Meigs JB, Dupuis J. Selection of the most informative individuals from families with multiple siblings for association studies. Genet Epidemiol. 2009 May; 33(4):299-307.View Related Profiles.

Liu, Chunyu
Dupuis, Josee

PMID: 19025786; PMCID: PMC3747668; DOI: 10.1002/gepi.20380;

Liu C, Batliwalla F, Li W, Lee A, Roubenoff R, Beckman E, Khalili H, Damle A, Kern M, Furie R, Dupuis J, Plenge RM, Coenen MJ, Behrens TW, Carulli JP, Gregersen PK. Genome-wide association scan identifies candidate polymorphisms associated with differential response to anti-TNF treatment in rheumatoid arthritis. Mol Med. 2008 Sep-Oct; 14(9-10):575-81.View Related Profiles.

Liu, Chunyu
Dupuis, Josee

PMID: 18615156; PMCID: PMC2443997; DOI: 10.2119/2008-00056.Liu;

Meigs JB, Manning AK, Dupuis J, Liu C, Florez JC, Cupples LA. Ordered stratification to reduce heterogeneity in linkage to diabetes-related quantitative traits. Obesity (Silver Spring). 2008 Oct; 16(10):2314-22.View Related Profiles.

Liu, Chunyu
Dupuis, Josee
Cupples, L

PMID: 18719643; PMCID: PMC3747653; DOI: 10.1038/oby.2008.354;

Meigs JB, Manning AK, Fox CS, Florez JC, Liu C, Cupples LA, Dupuis J. Genome-wide association with diabetes-related traits in the Framingham Heart Study. BMC Med Genet. 2007; 8 Suppl 1:S16.View Related Profiles.

Liu, Chunyu
Dupuis, Josee
Cupples, L

PMID: 17903298; PMCID: PMC1995610; DOI: 10.1186/1471-2350-8-S1-S16;

O'Donnell CJ, Cupples LA, D'Agostino RB, Fox CS, Hoffmann U, Hwang SJ, Ingellson E, Liu C, Murabito JM, Polak JF, Wolf PA, Demissie S. Genome-wide association study for subclinical atherosclerosis in major arterial territories in the NHLBI's Framingham Heart Study. BMC Med Genet. 2007; 8 Suppl 1:S4.View Related Profiles.

O'Donnell, Christopher
Liu, Chunyu
Murabito, Joanne
Polak, Joseph
Cupples, L
Wolf, Philip
D'Agostino, Ralph
Demissie, Serkalem
Hwang, Shih-Jen

PMID: 17903303; PMCID: PMC1995605; DOI: 10.1186/1471-2350-8-S1-S4;

Plenge RM, Seielstad M, Padyukov L, Lee AT, Remmers EF, Ding B, Liew A, Khalili H, Chandrasekaran A, Davies LR, Li W, Tan AK, Bonnard C, Ong RT, Thalamuthu A, Pettersson S, Liu C, Tian C, Chen WV, Carulli JP, Beckman EM, Altshuler D, Alfredsson L, Criswell LA, Amos CI, Seldin MF, Kastner DL, Klareskog L, Gregersen PK. TRAF1-C5 as a risk locus for rheumatoid arthritis--a genomewide study. N Engl J Med. 2007 Sep 20; 357(12):1199-209. PMID: 17804836; PMCID: PMC2636867; DOI: 10.1056/NEJMoa073491;

Fox CS, Massaro JM, Hoffmann U, Pou KM, Maurovich-Horvat P, Liu CY, Vasan RS, Murabito JM, Meigs JB, Cupples LA, D'Agostino RB, O'Donnell CJ. Abdominal visceral and subcutaneous adipose tissue compartments: association with metabolic risk factors in the Framingham Heart Study. Circulation. 2007 Jul 3; 116(1):39-48.View Related Profiles.

O'Donnell, Christopher
Liu, Chunyu
Murabito, Joanne
Massaro, Joseph
Cupples, L
D'Agostino, Ralph
Ramachandran, Vasan

PMID: 17576866

Maia AL, Dupuis J, Manning A, Liu C, Meigs JB, Cupples LA, Larsen PR, Fox CS. The type 2 deiodinase (DIO2) A/G polymorphism is not associated with glycemic traits: the Framingham Heart Study. Thyroid. 2007 Mar; 17(3):199-202.View Related Profiles.

Liu, Chunyu
Dupuis, Josee
Cupples, L

PMID: 17381351

Cupples LA, Arruda HT, Benjamin EJ, D'Agostino RB, Demissie S, DeStefano AL, Dupuis J, Falls KM, Fox CS, Gottlieb DJ, Govindaraju DR, Guo CY, Heard-Costa NL, Hwang SJ, Kathiresan S, Kiel DP, Laramie JM, Larson MG, Levy D, Liu CY, Lunetta KL, Mailman MD, Manning AK, Meigs JB, Murabito JM, Newton-Cheh C, O'Connor GT, O'Donnell CJ, Pandey M, Seshadri S, Vasan RS, Wang ZY, Wilk JB, Wolf PA, Yang Q, Atwood LD. The Framingham Heart Study 100K SNP genome-wide association study resource: overview of 17 phenotype working group reports. BMC Med Genet. 2007; 8 Suppl 1:S1.View Related Profiles.

DeStefano, Anita
O'Donnell, Christopher
Liu, Chunyu
Benjamin, Emelia
O'Connor, George
Murabito, Joanne
Dupuis, Josee
Lunetta, Kathryn
Cupples, L
Larson, Martin
Heard-Costa, Nancy
Wolf, Philip
Yang, Qiong
D'Agostino, Ralph
Demissie, Serkalem
Hwang, Shih-Jen
Seshadri, Sudha
Ramachandran, Vasan

PMID: 17903291; PMCID: PMC1995613; DOI: 10.1186/1471-2350-8-S1-S1;

Herbert A, Liu C, Karamohamed S, Liu J, Manning A, Fox CS, Meigs JB, Cupples LA. BMI modifies associations of IL-6 genotypes with insulin resistance: the Framingham Study. Obesity (Silver Spring). 2006 Aug; 14(8):1454-61.View Related Profiles.

Herbert, Alan
Liu, Chunyu
Cupples, L

PMID: 16988089

Meigs JB, Dupuis J, Liu C, O'Donnell CJ, Fox CS, Kathiresan S, Gabriel SB, Larson MG, Yang Q, Herbert AG, Wilson PW, Feng D, Tofler GH, Cupples LA. PAI-1 Gene 4G/5G polymorphism and risk of type 2 diabetes in a population-based sample. Obesity (Silver Spring). 2006 May; 14(5):753-8.View Related Profiles.

Herbert, Alan
O'Donnell, Christopher
Liu, Chunyu
Dupuis, Josee
Cupples, L
Larson, Martin

PMID: 16855181

Lakshman DK, Liu C, Mishra PK, Tavantzis S. Characterization of the arom gene in Rhizoctonia solani, and transcription patterns under stable and induced hypovirulence conditions. Curr Genet. 2006 Mar; 49(3):166-77. PMID: 16479402; DOI: 10.1007/s00294-005-0005-6;

Liu C, Cupples LA, Dupuis J. Comparisons of case-selection approaches based on allele sharing and/or disease severity index: application to the GAW14 simulated data. BMC Genet. 2005; 6 Suppl 1:S103.View Related Profiles.

Liu, Chunyu
Dupuis, Josee
Cupples, L

PMID: 16451559; PMCID: PMC1866836; DOI: 10.1186/1471-2156-6-S1-S103;

Herbert A, Liu C, Karamohamed S, Schiller J, Liu J, Yang Q, Wilson PW, Cupples LA, Meigs JB. The -174 IL-6 GG genotype is associated with a reduced risk of type 2 diabetes mellitus in a family sample from the National Heart, Lung and Blood Institute's Framingham Heart Study. Diabetologia. 2005 Aug; 48(8):1492-5.View Related Profiles.

Herbert, Alan
Liu, Chunyu
Cupples, L
Yang, Qiong

PMID: 15965659

Meigs JB, Dupuis J, Herbert AG, Liu C, Wilson PW, Cupples LA. The insulin gene variable number tandem repeat and risk of type 2 diabetes in a population-based sample of families and unrelated men and women. J Clin Endocrinol Metab. 2005 Feb; 90(2):1137-43.View Related Profiles.

Herbert, Alan
Liu, Chunyu
Dupuis, Josee
Cupples, L

PMID: 15562019

Karamohamed S, Demissie S, Volcjak J, Liu C, Heard-Costa N, Liu J, Shoemaker CM, Panhuysen CI, Meigs JB, Wilson P, Atwood LD, Cupples LA, Herbert A. Polymorphisms in the insulin-degrading enzyme gene are associated with type 2 diabetes in men from the NHLBI Framingham Heart Study. Diabetes. 2003 Jun; 52(6):1562-7.View Related Profiles.

Herbert, Alan
Liu, Chunyu
Cupples, L
Heard-Costa, Nancy
Demissie, Serkalem

PMID: 12765971

Liu C, Lakshman DK, Tavantzis SM. Quinic acid induces hypovirulence and expression of a hypovirulence-associated double-stranded RNA in Rhizoctonia solani. Curr Genet. 2003 May; 43(2):103-11. PMID: 12695850; DOI: 10.1007/s00294-003-0375-6;

Liu C, Lakshman DK, Tavantzis SM. Expression of a hypovirulence-causing double-stranded RNA is associated with up-regulation of quinic acid pathway and down-regulation of shikimic acid pathway in Rhizoctonia solani. Curr Genet. 2003 Feb; 42(5):284-91. PMID: 12589468; DOI: 10.1007/s00294-002-0348-1;

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 186 publications over 23 distinct years, with a maximum of 22 publications in 2022

Bar chart showing 186 publications over 23 distinct years, with a maximum of 22 publications in 2022

Year	Publications
2003	3
2004	1
2005	2
2006	3
2007	6
2008	2
2009	1
2011	2
2012	2
2013	2
2014	3
2015	7
2016	10
2017	14
2018	13
2019	13
2020	11
2021	14
2022	22
2023	16
2024	18
2025	18
2026	3

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In addition to these self-described keywords below, a list of MeSH based concepts is available here.

Genomewide associaiton study, mitochondrial DNA, DNA methylation and cardiovascular disease

Dr. Liu's commitment to academia encompasses both teaching and mentoring. She has taught several graduate-level courses including two core courses for the MS and PhD programs in Biostatistics. Dr. Liu's dedication extends to mentoring junior faculty members, postdoctoral fellows, and students enrolled in various programs—ranging from PhD and MS to MPH. At present, Dr. Liu is the primary mentor for four PhD students. Furthermore, she holds crucial administrative positions, co-directing the MS in Applied Biostatistics and serving as co-chair of the Department PhD Career Development Committee and the Student Paper Competition Committee.

Available to Mentor as: (Review Mentor Role Definitions):