{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T02:45:53Z","timestamp":1775011553571,"version":"3.50.1"},"reference-count":52,"publisher":"MIT Press - Journals","issue":"11","content-domain":{"domain":["direct.mit.edu"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2010,11,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Human electrophysiological research is generally restricted to scalp EEG, magneto-encephalography, and intracranial electrophysiology. Here we examine a unique patient cohort that has undergone decompressive hemicraniectomy, a surgical procedure wherein a portion of the calvaria is removed for several months during which time the scalp overlies the brain without intervening bone. We quantify the differences in signals between electrodes over areas with no underlying skull and scalp EEG electrodes over the intact skull in the same subjects. Signals over the hemicraniectomy have enhanced amplitude and greater task-related power at higher frequencies (60\u2013115 Hz) compared with signals over skull. We also provide evidence of a metric for trial-by-trial EMG\/EEG coupling that is effective over the hemicraniectomy but not intact skull at frequencies &amp;gt;60 Hz. Taken together, these results provide evidence that the hemicraniectomy model provides a means for studying neural dynamics in humans with enhanced spatial and temporal resolution.<\/jats:p>","DOI":"10.1162\/jocn.2009.21384","type":"journal-article","created":{"date-parts":[[2009,11,20]],"date-time":"2009-11-20T04:59:10Z","timestamp":1258693150000},"page":"2491-2502","update-policy":"https:\/\/2.zoppoz.workers.dev:443\/https\/doi.org\/10.1162\/mitpressjournals.corrections.policy","source":"Crossref","is-referenced-by-count":51,"title":["Hemicraniectomy: A New Model for Human Electrophysiology with High Spatio-temporal Resolution"],"prefix":"10.1162","volume":"22","author":[{"given":"Bradley","family":"Voytek","sequence":"first","affiliation":[{"name":"1University of California, Berkeley, CA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lavi","family":"Secundo","sequence":"additional","affiliation":[{"name":"1University of California, Berkeley, CA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aurelie","family":"Bidet-Caulet","sequence":"additional","affiliation":[{"name":"1University of California, Berkeley, CA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Donatella","family":"Scabini","sequence":"additional","affiliation":[{"name":"1University of California, Berkeley, CA"},{"name":"2University of California, San Francisco, CA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shirley I.","family":"Stiver","sequence":"additional","affiliation":[{"name":"2University of California, San Francisco, CA"},{"name":"3San Francisco General Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alisa D.","family":"Gean","sequence":"additional","affiliation":[{"name":"2University of California, San Francisco, CA"},{"name":"3San Francisco General Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Geoffrey T.","family":"Manley","sequence":"additional","affiliation":[{"name":"2University of California, San Francisco, CA"},{"name":"3San Francisco General Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert T.","family":"Knight","sequence":"additional","affiliation":[{"name":"1University of California, Berkeley, CA"},{"name":"2University of California, San Francisco, CA"},{"name":"3San Francisco General Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"281","published-online":{"date-parts":[[2010,11,1]]},"reference":[{"key":"2021072900461622500_R1","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1016\/0013-4694(58)90006-3","article-title":"Patterns of cortical discharges and their relation to routine scalp electroencephalography.","volume":"10","author":"Abraham","year":"1958","journal-title":"Electroencephalography and Clinical 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