{"id":"https://openalex.org/W1983307067","doi":"https://doi.org/10.4204/eptcs.92.8","title":"Effects of delayed immune-response in tumor immune-system interplay","display_name":"Effects of delayed immune-response in tumor immune-system interplay","publication_year":2012,"publication_date":"2012-08-15","ids":{"openalex":"https://openalex.org/W1983307067","doi":"https://doi.org/10.4204/eptcs.92.8","mag":"1983307067"},"language":"en","primary_location":{"id":"doi:10.4204/eptcs.92.8","is_oa":true,"landing_page_url":"https://doi.org/10.4204/eptcs.92.8","pdf_url":"https://arxiv.org/pdf/1208.3855","source":{"id":"https://openalex.org/S4210216316","display_name":"Electronic Proceedings in Theoretical Computer Science","issn_l":"2075-2180","issn":["2075-2180"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310318029","host_organization_name":"Open Publishing Association","host_organization_lineage":["https://openalex.org/P4310318029"],"host_organization_lineage_names":["Open Publishing Association"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Electronic Proceedings in Theoretical Computer Science","raw_type":"journal-article"},"type":"article","indexed_in":["arxiv","crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://arxiv.org/pdf/1208.3855","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5033643165","display_name":"Giulio Caravagna","orcid":"https://orcid.org/0000-0003-4240-3265"},"institutions":[{"id":"https://openalex.org/I66752286","display_name":"University of Milano-Bicocca","ror":"https://ror.org/01ynf4891","country_code":"IT","type":"education","lineage":["https://openalex.org/I66752286"]}],"countries":["IT"],"is_corresponding":true,"raw_author_name":"Giulio Caravagna","raw_affiliation_strings":["Dipartimento di Informatica Sistemistica e Comunicazione, Universit\u00e0 degli Studi Milano-Bicocca, Viale Sarca 336, I-20126 Milan, Italy"],"affiliations":[{"raw_affiliation_string":"Dipartimento di Informatica Sistemistica e Comunicazione, Universit\u00e0 degli Studi Milano-Bicocca, Viale Sarca 336, I-20126 Milan, Italy","institution_ids":["https://openalex.org/I66752286"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055916343","display_name":"Alex Graudenzi","orcid":"https://orcid.org/0000-0001-5452-1918"},"institutions":[{"id":"https://openalex.org/I66752286","display_name":"University of Milano-Bicocca","ror":"https://ror.org/01ynf4891","country_code":"IT","type":"education","lineage":["https://openalex.org/I66752286"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Alex Graudenzi","raw_affiliation_strings":["Dipartimento di Informatica Sistemistica e Comunicazione, Universit\u00e0 degli Studi Milano-Bicocca, Viale Sarca 336, I-20126 Milan, Italy"],"affiliations":[{"raw_affiliation_string":"Dipartimento di Informatica Sistemistica e Comunicazione, Universit\u00e0 degli Studi Milano-Bicocca, Viale Sarca 336, I-20126 Milan, Italy","institution_ids":["https://openalex.org/I66752286"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037919963","display_name":"Marco Antoniotti","orcid":"https://orcid.org/0000-0002-2823-6838"},"institutions":[{"id":"https://openalex.org/I66752286","display_name":"University of Milano-Bicocca","ror":"https://ror.org/01ynf4891","country_code":"IT","type":"education","lineage":["https://openalex.org/I66752286"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Marco Antoniotti","raw_affiliation_strings":["Dipartimento di Informatica Sistemistica e Comunicazione, Universit\u00e0 degli Studi Milano-Bicocca, Viale Sarca 336, I-20126 Milan, Italy"],"affiliations":[{"raw_affiliation_string":"Dipartimento di Informatica Sistemistica e Comunicazione, Universit\u00e0 degli Studi Milano-Bicocca, Viale Sarca 336, I-20126 Milan, Italy","institution_ids":["https://openalex.org/I66752286"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073163964","display_name":"Giancarlo Mauri","orcid":"https://orcid.org/0000-0003-3520-4022"},"institutions":[{"id":"https://openalex.org/I66752286","display_name":"University of Milano-Bicocca","ror":"https://ror.org/01ynf4891","country_code":"IT","type":"education","lineage":["https://openalex.org/I66752286"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Giancarlo Mauri","raw_affiliation_strings":["Dipartimento di Informatica Sistemistica e Comunicazione, Universit\u00e0 degli Studi Milano-Bicocca, Viale Sarca 336, I-20126 Milan, Italy"],"affiliations":[{"raw_affiliation_string":"Dipartimento di Informatica Sistemistica e Comunicazione, Universit\u00e0 degli Studi Milano-Bicocca, Viale Sarca 336, I-20126 Milan, Italy","institution_ids":["https://openalex.org/I66752286"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5074676799","display_name":"Alberto d\u2019Onofrio","orcid":"https://orcid.org/0000-0002-2190-272X"},"institutions":[{"id":"https://openalex.org/I4210123579","display_name":"Ripamonti","ror":"https://ror.org/03vcgp521","country_code":"IT","type":"company","lineage":["https://openalex.org/I4210123579"]},{"id":"https://openalex.org/I6141010","display_name":"European Institute of Oncology","ror":"https://ror.org/02vr0ne26","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210153126","https://openalex.org/I6141010"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Alberto d'Onofrio","raw_affiliation_strings":["Department of Experimental Oncology, European Institute of Oncology, Via Ripamonti 435, 20141 Milan, Italy"],"affiliations":[{"raw_affiliation_string":"Department of Experimental Oncology, European Institute of Oncology, Via Ripamonti 435, 20141 Milan, Italy","institution_ids":["https://openalex.org/I6141010","https://openalex.org/I4210123579"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5033643165"],"corresponding_institution_ids":["https://openalex.org/I66752286"],"apc_list":null,"apc_paid":null,"fwci":1.3149,"has_fulltext":true,"cited_by_count":6,"citation_normalized_percentile":{"value":0.77455647,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"92","issue":null,"first_page":"106","last_page":"121"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11829","display_name":"Mathematical Biology Tumor Growth","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/2611","display_name":"Modeling and Simulation"},"field":{"id":"https://openalex.org/fields/26","display_name":"Mathematics"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T11829","display_name":"Mathematical Biology Tumor Growth","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/2611","display_name":"Modeling and Simulation"},"field":{"id":"https://openalex.org/fields/26","display_name":"Mathematics"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10621","display_name":"Gene Regulatory Network Analysis","score":0.9987000226974487,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11178","display_name":"Receptor Mechanisms and Signaling","score":0.9449999928474426,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/immune-system","display_name":"Immune system","score":0.6073068380355835},{"id":"https://openalex.org/keywords/effector","display_name":"Effector","score":0.5442978143692017},{"id":"https://openalex.org/keywords/stochastic-process","display_name":"Stochastic process","score":0.43752166628837585},{"id":"https://openalex.org/keywords/markov-process","display_name":"Markov process","score":0.4209229052066803},{"id":"https://openalex.org/keywords/biological-system","display_name":"Biological system","score":0.41080614924430847},{"id":"https://openalex.org/keywords/control-theory","display_name":"Control theory (sociology)","score":0.37368208169937134},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.36817628145217896},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.3536478877067566},{"id":"https://openalex.org/keywords/physics","display_name":"Physics","score":0.34740543365478516},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.268038809299469},{"id":"https://openalex.org/keywords/immunology","display_name":"Immunology","score":0.18559834361076355},{"id":"https://openalex.org/keywords/statistics","display_name":"Statistics","score":0.15347927808761597},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.11808949708938599},{"id":"https://openalex.org/keywords/control","display_name":"Control (management)","score":0.09700018167495728}],"concepts":[{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.6073068380355835},{"id":"https://openalex.org/C51785407","wikidata":"https://www.wikidata.org/wiki/Q2627568","display_name":"Effector","level":2,"score":0.5442978143692017},{"id":"https://openalex.org/C8272713","wikidata":"https://www.wikidata.org/wiki/Q176737","display_name":"Stochastic process","level":2,"score":0.43752166628837585},{"id":"https://openalex.org/C159886148","wikidata":"https://www.wikidata.org/wiki/Q176645","display_name":"Markov process","level":2,"score":0.4209229052066803},{"id":"https://openalex.org/C186060115","wikidata":"https://www.wikidata.org/wiki/Q30336093","display_name":"Biological system","level":1,"score":0.41080614924430847},{"id":"https://openalex.org/C47446073","wikidata":"https://www.wikidata.org/wiki/Q5165890","display_name":"Control theory (sociology)","level":3,"score":0.37368208169937134},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.36817628145217896},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.3536478877067566},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.34740543365478516},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.268038809299469},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.18559834361076355},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.15347927808761597},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.11808949708938599},{"id":"https://openalex.org/C2775924081","wikidata":"https://www.wikidata.org/wiki/Q55608371","display_name":"Control (management)","level":2,"score":0.09700018167495728}],"mesh":[],"locations_count":6,"locations":[{"id":"doi:10.4204/eptcs.92.8","is_oa":true,"landing_page_url":"https://doi.org/10.4204/eptcs.92.8","pdf_url":"https://arxiv.org/pdf/1208.3855","source":{"id":"https://openalex.org/S4210216316","display_name":"Electronic Proceedings in Theoretical Computer Science","issn_l":"2075-2180","issn":["2075-2180"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310318029","host_organization_name":"Open Publishing Association","host_organization_lineage":["https://openalex.org/P4310318029"],"host_organization_lineage_names":["Open Publishing Association"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Electronic Proceedings in Theoretical Computer Science","raw_type":"journal-article"},{"id":"pmh:oai:arXiv.org:1208.3855","is_oa":true,"landing_page_url":"http://arxiv.org/abs/1208.3855","pdf_url":"https://arxiv.org/pdf/1208.3855","source":{"id":"https://openalex.org/S4306400194","display_name":"arXiv (Cornell University)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I205783295","host_organization_name":"Cornell University","host_organization_lineage":["https://openalex.org/I205783295"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"text"},{"id":"pmh:oai:arts.units.it:11368/2956356","is_oa":false,"landing_page_url":"http://hdl.handle.net/11368/2956356","pdf_url":null,"source":{"id":"https://openalex.org/S4306400480","display_name":"ArTS Archivio della ricerca di Trieste (University of Trieste https://www.units.it/)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I142444530","host_organization_name":"University of Trieste","host_organization_lineage":["https://openalex.org/I142444530"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:boa.unimib.it:10281/37542","is_oa":true,"landing_page_url":"http://hdl.handle.net/10281/37542","pdf_url":null,"source":{"id":"https://openalex.org/S4306401259","display_name":"BOA (University of Milano-Bicocca)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I66752286","host_organization_name":"University of Milano-Bicocca","host_organization_lineage":["https://openalex.org/I66752286"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:doaj.org/article:df04f28e6b724bb88acbf4b0dc69742a","is_oa":true,"landing_page_url":"https://doaj.org/article/df04f28e6b724bb88acbf4b0dc69742a","pdf_url":null,"source":{"id":"https://openalex.org/S112646816","display_name":"SHILAP Revista de lepidopterolog\u00eda","issn_l":"0300-5267","issn":["0300-5267","2340-4078"],"is_oa":true,"is_in_doaj":true,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Electronic Proceedings in Theoretical Computer Science, Vol 92, Iss Proc. HSB 2012, Pp 106-121 (2012)","raw_type":"article"},{"id":"pmh:oai:pure.ed.ac.uk:publications/51b42619-e60d-4fda-8b78-a9c8d6cd52ad","is_oa":true,"landing_page_url":"https://www.research.ed.ac.uk/en/publications/51b42619-e60d-4fda-8b78-a9c8d6cd52ad","pdf_url":null,"source":{"id":"https://openalex.org/S4406922455","display_name":"Edinburgh Research Explorer","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":""}],"best_oa_location":{"id":"doi:10.4204/eptcs.92.8","is_oa":true,"landing_page_url":"https://doi.org/10.4204/eptcs.92.8","pdf_url":"https://arxiv.org/pdf/1208.3855","source":{"id":"https://openalex.org/S4210216316","display_name":"Electronic Proceedings in Theoretical Computer Science","issn_l":"2075-2180","issn":["2075-2180"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310318029","host_organization_name":"Open Publishing Association","host_organization_lineage":["https://openalex.org/P4310318029"],"host_organization_lineage_names":["Open Publishing Association"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Electronic Proceedings in Theoretical Computer Science","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Life in Land","id":"https://metadata.un.org/sdg/15","score":0.699999988079071}],"awards":[],"funders":[{"id":"https://openalex.org/F4320326078","display_name":"Regione Lombardia","ror":null}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1983307067.pdf","grobid_xml":"https://content.openalex.org/works/W1983307067.grobid-xml"},"referenced_works_count":58,"referenced_works":["https://openalex.org/W91439453","https://openalex.org/W110544557","https://openalex.org/W1484033701","https://openalex.org/W1579641819","https://openalex.org/W1883106989","https://openalex.org/W1972914572","https://openalex.org/W1973913634","https://openalex.org/W1974932725","https://openalex.org/W1979575182","https://openalex.org/W1982492209","https://openalex.org/W1989128995","https://openalex.org/W1990263529","https://openalex.org/W2001548992","https://openalex.org/W2007991168","https://openalex.org/W2022743324","https://openalex.org/W2027065943","https://openalex.org/W2028079360","https://openalex.org/W2029159090","https://openalex.org/W2033579796","https://openalex.org/W2034669041","https://openalex.org/W2040837794","https://openalex.org/W2042321087","https://openalex.org/W2042937188","https://openalex.org/W2053364576","https://openalex.org/W2054884080","https://openalex.org/W2058751541","https://openalex.org/W2064206581","https://openalex.org/W2067149140","https://openalex.org/W2081613860","https://openalex.org/W2089961542","https://openalex.org/W2094631910","https://openalex.org/W2098958083","https://openalex.org/W2099948781","https://openalex.org/W2100679270","https://openalex.org/W2101511753","https://openalex.org/W2102333202","https://openalex.org/W2103071636","https://openalex.org/W2114062458","https://openalex.org/W2116148182","https://openalex.org/W2118395022","https://openalex.org/W2121626779","https://openalex.org/W2124149894","https://openalex.org/W2141262236","https://openalex.org/W2148638342","https://openalex.org/W2154911496","https://openalex.org/W2155418451","https://openalex.org/W2159064053","https://openalex.org/W2159278787","https://openalex.org/W2169169493","https://openalex.org/W2286035120","https://openalex.org/W2325337867","https://openalex.org/W2471704267","https://openalex.org/W3142252479","https://openalex.org/W4234011924","https://openalex.org/W4241424808","https://openalex.org/W4245470749","https://openalex.org/W4252710111","https://openalex.org/W4298092629"],"related_works":["https://openalex.org/W4320492283","https://openalex.org/W1530034981","https://openalex.org/W4214695225","https://openalex.org/W3197607994","https://openalex.org/W1567439243","https://openalex.org/W1993731165","https://openalex.org/W2095860056","https://openalex.org/W2742871814","https://openalex.org/W2134216493","https://openalex.org/W2802778578"],"abstract_inverted_index":{"Tumors":[0],"constitute":[1],"a":[2,70,112,148,157,163,196,239],"wide":[3],"family":[4],"of":[5,12,24,47,73,79,92,114,116,138,177,238],"diseases":[6],"kinetically":[7],"characterized":[8],"by":[9,105,184,252,256],"the":[10,74,93,106,135,178,186,192,233,236,253,257],"co-presence":[11],"multiple":[13],"spatio-temporal":[14],"scales.":[15],"So,":[16],"tumor":[17,41,80,103,208,246],"cells":[18,28,83],"ecologically":[19],"interplay":[20],"with":[21,162,195,211],"other":[22],"kind":[23],"cells,":[25,81],"e.g.":[26],"endothelial":[27],"or":[29],"immune":[30,100,107,139],"system":[31],"effectors,":[32],"producing":[33],"and":[34,59,84,132,215,228],"exchanging":[35],"various":[36],"chemical":[37,63,130],"signals.":[38,64],"As":[39],"such,":[40],"growth":[42,210],"is":[43,141,182,249],"an":[44],"ideal":[45],"object":[46],"hybrid":[48,71,87,193,258],"modeling":[49],"where":[50],"discrete":[51],"stochastic":[52,118,166,180,241],"processes":[53],"model":[54,62,78,88,122],"agents":[55],"at":[56],"low":[57],"concentrations,":[58],"mean-field":[60,77,158,254],"equations":[61],"In":[65],"previous":[66],"works":[67],"we":[68,154,222,230],"proposed":[69],"version":[72],"well-known":[75],"Panetta-Kirschner":[76],"effector":[82],"Interleukin-2.":[85],"Our":[86],"suggested":[89],"-at":[90],"variance":[91],"inferences":[94],"from":[95],"its":[96],"original":[97],"formulation-":[98],"that":[99,121],"surveillance,":[101],"i.e.":[102],"elimination":[104],"system,":[108],"may":[109],"occur":[110],"through":[111],"sort":[113],"side-effect":[115],"large":[117],"oscillations.":[119],"However,":[120],"did":[123],"not":[124,142],"account":[125,202],"that,":[126],"due":[127],"to":[128,174],"both":[129],"transportation":[131],"cellular":[133],"differentiation/division,":[134],"tumor-induced":[136],"recruitment":[137],"effectors":[140],"instantaneous":[143],"but,":[144],"instead,":[145],"it":[146],"exhibits":[147],"lag":[149],"period.":[150],"To":[151],"capture":[152],"this,":[153],"here":[155],"integrate":[156],"equation":[159],"for":[160,203],"Interleukins-2":[161],"bi-dimensional":[164],"delayed":[165,170],"process":[167,181,190],"describing":[168],"such":[169],"interplay.":[171],"An":[172],"algorithm":[173],"realize":[175],"trajectories":[176],"underlying":[179],"obtained":[183],"coupling":[185],"Piecewise":[187],"Deterministic":[188],"Markov":[189],"(for":[191],"part)":[194],"Generalized":[197],"Semi-Markovian":[198],"clock":[199],"structure":[200],"(to":[201],"delays).":[204],"We":[205],"(i)":[206],"relate":[207],"mass":[209],"delays":[212],"via":[213,216],"simulations":[214],"parametric":[217],"sensitivity":[218],"analysis":[219],"techniques,":[220],"(ii)":[221],"quantitatively":[223],"determine":[224],"probabilistic":[225],"eradication":[226],"times,":[227],"(iii)":[229],"prove,":[231],"in":[232,244],"oscillatory":[234],"regime,":[235],"existence":[237],"heuristic":[240],"bifurcation":[242],"resulting":[243],"delay-induced":[245],"eradication,":[247],"which":[248],"neither":[250],"predicted":[251],"nor":[255],"non-delayed":[259],"models.":[260]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2014,"cited_by_count":4},{"year":2012,"cited_by_count":1}],"updated_date":"2026-03-10T16:38:18.471706","created_date":"2025-10-10T00:00:00"}