We introduce the Multi-Objective Combinatorial Reconfiguration Optimization Problem (MO-CROP), and propose an Answer Set Programming (ASP) based approach for its solution. MO-CROP involves finding the Pareto-optimal sequences (or Pareto front) of adjacent feasible solutions between two given feasible solutions of a combinatorial problem, considering both cost and length. Our algorithm is compactly implemented through multi-shot ASP solving, and its implementing solver optirecon provides an effective tool for solving MO-CROP. As a concrete example of MO-CROP, we present an ASP encoding for solving the multi-objective independent set reconfiguration optimization problem. Experimental results on the benchmark set from the recent CoRe Challenge demonstrate our approach’s ability to capture diverse optimal sequences that reveal trade-offs between cost and length, a capability often lacking in traditional combinatorial reconfiguration methods.