Brain structure and activity predicting cognitive maturation in adolescence
Authors/Creators
Description
BIDS_Garin_Zhu_Constantinidis.zip:
Longitudinal MRI dataset of 8 macaques monkeys scanned every 3 months (11 sessions) at Wake Forest Universtity
This dataset includes: anatomical MRI (T1, T2, T2 Flair), fonctional MRI, and fmap
Structural MRIs were collected from the monkeys of cohort A every 3 months from 2.8 years (34
months) of age to 5.8 years (69 months) of age. In preparation for the MRI scan, anesthesia was
induced using ketamine (5–10mg/kg) and dexmedetomidine (0.015mg/kg), and was maintained
using isoflurane. The animals were intubated and artificially ventilated at about 20 breaths per
minute. Expired CO2 was monitored and maintained between 35 and 45 mmHg. Animals were
scanned under isoflurane anesthesia at 1%–1.5%. Heart rate and oxygen saturation levels were
monitored using a pulse oximeter. Their body temperature was maintained using warm blankets.
The MRI system was a 3 Tesla Siemens MAGNETOM Skyra (Siemens Healthcare, Erlangen,
Germany). Anatomical images were acquired using a T1-weighted MPRAGE sequence: TR = 2700
ms, TE = 3.32 ms, inversion time = 880, FOV = 128 × 128 mm, 192 slices of 0.5 mm thickness,
resolution = 0.5 mm isotropic. Resting state time series data were also acquired using a multiband
EPI sequence: TR = 700 ms, TE = 32.0 ms, flip angle = 52°, repetitions = 700, FOV = 128 × 128 mm,
32 slices, resolution = 2 mm isotropic.
Data are formated in standard BIDS format
cog_mat_ado_release.zip:
The code and used to process the results and generate the figures (also available in CodeOcean: https://codeocean.com/capsule/7858389/tree)
Files
BIDS_Garin_Zhu_Constantinidis.zip
Files
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Additional details
Related works
- Is published in
- Publication: 10.1101/2024.08.23.608315 (DOI)
Funding
- National Institutes of Health
- R01 MH117996
- National Institutes of Health
- R01 MH116675
Dates
- Created
-
2025-01-07
Software
- Repository URL
- https://github.com/garincle/EDNiX
- Programming language
- Python
- Development Status
- Wip