Published February 7, 2025 | Version V1.0
Dataset Open

Brain structure and activity predicting cognitive maturation in adolescence

  • 1. Institut des Sciences Cognitives Marc Jeannerod
  • 2. ROR icon Vanderbilt University
  • 3. ROR icon Cedars-Sinai Medical Center
  • 4. CNRS Délégation Rhône-Auvergne
  • 5. Wake Forest School of Medicine
  • 6. ROR icon University of Pittsburgh

Description

    
BIDS_Garin_Zhu_Constantinidis.zip:

Longitudinal MRI dataset of 8 macaques monkeys scanned every 3 months (11 sessions) at Wake Forest Universtity

This dataset includes: anatomical MRI  (T1, T2, T2 Flair), fonctional MRI, and fmap

Structural MRIs were collected from the monkeys of cohort A every 3 months from 2.8 years (34
months) of age to 5.8 years (69 months) of age. In preparation for the MRI scan, anesthesia was
induced using ketamine (5–10mg/kg) and dexmedetomidine (0.015mg/kg), and was maintained
using isoflurane. The animals were intubated and artificially ventilated at about 20 breaths per
minute. Expired CO2 was monitored and maintained between 35 and 45 mmHg. Animals were
scanned under isoflurane anesthesia at 1%–1.5%. Heart rate and oxygen saturation levels were
monitored using a pulse oximeter. Their body temperature was maintained using warm blankets.
The MRI system was a 3 Tesla Siemens MAGNETOM Skyra (Siemens Healthcare, Erlangen,
Germany). Anatomical images were acquired using a T1-weighted MPRAGE sequence: TR = 2700
ms, TE = 3.32 ms, inversion time = 880, FOV = 128 × 128 mm, 192 slices of 0.5 mm thickness,
resolution = 0.5 mm isotropic. Resting state time series data were also acquired using a multiband
EPI sequence: TR = 700 ms, TE = 32.0 ms, flip angle = 52°, repetitions = 700, FOV = 128 × 128 mm,
32 slices, resolution = 2 mm isotropic. 


Data are formated in standard BIDS format

 

    
cog_mat_ado_release.zip:
The code and used to process the results and generate the figures (also available in CodeOcean: https://codeocean.com/capsule/7858389/tree)

Files

BIDS_Garin_Zhu_Constantinidis.zip

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Additional details

Related works

Is published in
Publication: 10.1101/2024.08.23.608315 (DOI)

Funding

National Institutes of Health
R01 MH117996
National Institutes of Health
R01 MH116675

Dates

Created
2025-01-07

Software

Repository URL
https://github.com/garincle/EDNiX
Programming language
Python
Development Status
Wip