This paper presents a new common grounded (CG) multilevel boost inverter (MI) topology for single-phase grid-tied photovoltaic (PV) applications. The proposed topology has the capability to fully eliminate the leakage currents in PV systems due to the using of the CG connection. Additionally, the proposed topology benefits the high boosting factor capability of the low PV voltage. The proposed topology represents a single stage power conversion system with reduced power components compared to the traditional two-stage PV power conversion systems. In addition, model predictive controller (MPC) is proposed in this paper to control the proposed topology. The proposed controller can control multiple objectives simultaneously without using cascaded controllers. The simulation results with the different case studies are provided. The results confirm the superiority of the proposed CG boost MI topology and the proposed MPC method. Furthermore, fast tracking of the grid active and reactive power demands is achieved using the proposed MPC method.