Difference between Prokaryotic and Eukaryotic Cells

Last Updated : 19 Dec, 2025

Prokaryotic and eukaryotic cells are the two primary types of cells. Prokaryotic cells lack a defined nucleus and membrane-bound organelles, while eukaryotic cells have a true nucleus and membrane-bound organelles. Prokaryotes are smaller and simpler, found in bacteria and archaea, while eukaryotes are larger and more complex, found in animals, plants, fungi, and protists.

prokaryotic_cell

The difference between prokaryotes and eukaryotes is as follows:

Prokaryotes Cell

Eukaryotes Cell

Lack membrane-bound organelles, though they may have simpler structures like ribosomes.

Contain membrane-bound organelles such as mitochondria, endoplasmic reticulum, Golgi apparatus, lysosomes, and more.

Lacks a true nucleus. Genetic material is present in the nucleoid, not enclosed by a membrane.

Have a true nucleus enclosed by a nuclear membrane, containing genetic material (DNA).

The size of the cell is smaller (0.1–5 μm).

In comparison, the cell size is bigger (10-100 μm).

Single, circular chromosome (DNA). It may also contain plasmids.

Multiple linear chromosomes (DNA) are found in the nucleus.

This cell has a unicellular structure

Multicellular eukaryotic cells predominate. Nevertheless, some are monocellular.

Lysosomes and Peroxisomes are absent

Lysosomes and Peroxisomes present

Microtubules are absent

Microtubules are present

The endoplasmic reticulum is absent

The endoplasmic reticulum is present

Mitochondria are absent

Mitochondria are present

The cytoskeleton is absent

Cytoskeleton is present

Ribosomes are smaller

Ribosomes are larger

Vesicles are present

Vesicles are present

The cell wall is present

Cell wall not present

PK cell divides by binary fission 

Ek cell divides by a process known as mitosis.

Reproduce primarily through binary fission, a form of asexual reproduction.

Reproduce through mitosis (asexual) and meiosis (sexual) processes.

Present but smaller in size.

Large flagella.

Generally simpler in structure and function.

More complex structurally and functionally due to organelles and cellular compartmentalisation.

Archaea, Bacteria

Plant, Fungi, Animal Cell

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