2.
Recognition & management of
pregnancy-related
complications.19
SCREEN FOR:
Pre-eclampsia
Anemia
Syphilis
HIV status
Diabetes Mellitus
> 8 months
No clear evidence of benefit of routine antibiotic
and steroid use
< 8 months
Give antibiotic: ERYTHROMYCIN
Alternative: Ampicillin
Give corticosteroids if no sign of
infection
Betamethasone 12 mg IM q 24 hrs x 2 doses
OR
Dexamethasone 6 mg IM q 12 x 4 doses
Judicious Antibiotic Use: The
Evidence
PPROM (prolonged rupture of
membrane): Prolong pregnancy and
reduce neonatal morbidity in women
with gestation of 34 weeks
PTL (preterm labor): Little evidence of
benefit at a gestation 34 weeks.
Reduced the incidence of early onset
neonatal sepsis but caused ampicillinresistance and severe neonatal
infections
Antenatal Steroids: The
Evidence
Overall reduction in neonatal death
Reduction in RDS (respiratory disease
syndrome)
Reduction in cerebro-ventricular
hemorrhage
Reduction in necrotisingenterocolitis
Reduction in respiratory support and NICU
admissions
Reduction in sepsis in the first 48 hours of
life
Does not increase risk of death,
chorioamnionitis or puerperal sepsis in
the mother
No significant impact on
incidence of PPH (postpartumhemorrhage)
Important neonatal
outcomes:
Term babies: less anemia in
newborn 24-48 hrs after
birth
Preterms: less infant anemia
and less intraventricular
hemorrhage Uterine
Delayedcord
clamping
Controlled cord
traction with counter
traction on the uterus
Massage uterine
fundus
Reduction in blood loss of 1
Liter or more
Reduction in use of blood transfusion
Reduction in the use of additional
uterotonics Oxytocin alone preferred
over other uterotonic drugs
Ergometrine associated with more
adverse side effects compared to
oxytocin alone
No Maternal deaths reported
intraventricularhemorrhage
Uterine massage: The
Evidence
Less blood loss at 30 minutes
Less blood loss at 60 minutes
Reduction in the use of additional
uterotonics
The number of women losing >500
ml of blood approximately halved.
Two women in the control group and
none in the uterine massage group
needed blood transfusion