Generic Name: Brand Name: Classification: Dosage: Mechanism of Action

Ketorolac (brand name Toradol) is a nonsteroidal anti-inflammatory drug used for short term management of pain. It works by inhibiting prostaglandin synthesis to reduce pain, fever, and inflammation. It should be used cautiously in patients with a history of gastrointestinal bleeding, renal impairment, or cardiovascular disease due to potential side effects like gastrointestinal bleeding, renal toxicity, edema, and prolonged bleeding time. Nurses should assess pain levels before and after administration and advise patients to avoid other medications without consulting their healthcare provider due to risk of drug interactions.

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Amsh Rosal

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Topics covered

CNS effects,
injection site pain,
dizziness,
genitourinary effects,
pallor,
gastrointestinal effects,
oral therapy,
euphoria,
analgesics,
NSAID cross-sensitivity

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Generic Name: Brand Name: Classification: Dosage: Mechanism of Action

Uploaded by

Amsh Rosal

We take content rights seriously. If you suspect this is your content, claim it here.

Available Formats

Download as DOCX, PDF, TXT or read online on Scribd

Topics covered

CNS effects,
injection site pain,
dizziness,
genitourinary effects,
pallor,
gastrointestinal effects,
oral therapy,
euphoria,
analgesics,
NSAID cross-sensitivity

GENERIC NAME:

Ketorolac
BRAND NAME:
Toradol
CLASSIFICATION:
Nonsteroidal anti-inflammatory agents, nonopioid analagesics
DOSAGE:
30mg/amp1 amp IM
MECHANISM OF ACTION:
- Inhibits prostaglandin synthesis, producing peripherally mediated analgesia
- Also has antipyretic and anti-inflammatory properties.
- Therapeutic effect:Decreased pain
INDICATION:
Short term management of pain (not to exceed 5 days total for all routes
combined)
CONTRAINDICATIONS:
- Hypersensitivity
- Cross-sensitivity with other NSAIDs may exist¨Pre- or perioperative use
- Known alcohol intoleranceUse cautiously in:
1) History of GI bleeding
2) Renal impair-ment (dosage reduction may be required)
3) Cardiovascular disease
SIDE EFFECTS/ ADVERSE EFFECTS:
- CNS:
1) drowsiness
2) abnormal thinking
3) dizziness
4) euphoria
5) headache-
- RESP:
1) asthma
2) dyspnea
- CV:
1) edema
2) pallor
3) vasodilation
- GI:
1) GI Bleeding
2) abnormal taste
3) diarrhea
4) dry mouth
5) dyspepsia
6) GI pain
7) nausea
- GU:
1) oliguria
2) renal toxicity
3) urinary frequency
- DERM:
1) pruritis
2) purpura
3) sweating
4) urticaria
- HEMAT:
1) prolonged bleeding time
- LOCAL:
1) injection site pain
- NEURO:
1) paresthesia
- MISC:
1) allergic reaction, anaphylaxis
NURSING IMPLICATIONS/RESPONSIBILITIES:
- Patients who have asthma, aspirin-induced allergy, and nasal polyps are at
increased risk for developing hypersensitivity reactions. Assess for rhinitis,
asthma, and urticaria.
- Assess pain (note type, location, and intensity) prior to and 1-2 hr following
administration.
- Ketorolac therapy should always be given initially by the IM or IV route. Oral
therapy should be used only as a continuation of parenteral therapy.
- Caution patient to avoid concurrent use of alcohol, aspirin, NSAIDs,
acetaminophen, or other OTC medications without consulting health care
professional.
- Advise patient to consult if rash, itching, visual disturbances, tinnitus,
weight gain, edema, black stools, persistent headche, or influenza-like
syndromes (chills,fever,muscles aches, pain) occur.
- Effectiveness of therapy can be demonstrated by decrease in severity of
pain. Patients who do not respond to one NSAIDs may respond to another.
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Generic Name: Brand Name: Classification: Dosage: Mechanism of Action

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