Major objectives/ Delineated Factors/ Methods, Data
Bibliography Central objective/Main Variables/Main Gathering, Tool, Major Finding
objective problem Subjects/ Participants
Arquion, C., Nuñeza, O., This study is conducted Ficus nota This study was The stem extracts of
& Uy, M. (2015, to investigate the conducted to test for in Ficus nota exhibited
November). Evaluating potential cytotoxic vivo brine shrimp cytotoxic activity against
the Potential Cytotoxic activity of Ficus nota lethality of Ficus nota. the brine shrimp Artemia
Activity of Ficus nota using Brine Shrimp salina.
Using Brine Shrimp Lethality Test (BSLT). Plant extracts were
Lethality Test. Bulletin of obtained through After 24 hours, ethanolic
Environment, extraction of the stem extract showed greater
Pharmacology and Life samples with water and cytotoxic activity
Sciences, 4(12). absolute ethanol. compared to the
Retrieved September 1, decoction extract.
2018 Three concentrations
(100 ppm, 500 ppm, and This further warrant
1000 ppm) of the phytochemical
extracts were tested and screening of the
mortality of Artemia ethanolic extracts of F.
salina was noted after nota for the
24 h exposure. determination of its
active cytotoxic
components.
Major objectives/ Delineated Factors/ Methods, Data
Bibliography Central objective/Main Variables/Main Gathering, Tool, Major Finding
objective problem Subjects/ Participants
Ettebong, E., Nwafor, The aim of this study is Eluesine indica The rats of both sexes The results showed that
P., Ubulom, P., & to evaluate the were randomized into 5 organ weights were not
Udobang, J. (2017, toxicological effects of groups of 6 animals per affected but animal
March 3). The the extract in adult group and orally weights increased
toxicological albino Wistar rats. administered with significantly (P < 0.01-
assessment of ethanolic extract (200, 400 and 0.001).
whole-plant extract of 600 mg/kg) for groups
Eleucine indica in Wistar 2–4, respectively. Group Relative organ weights
albino rats. Journal of 1 received were not affected. The
Herbmed distilled water (10 extract caused, at low
Pharmacology, 6(2). mL/kg) orally and served doses, slight
Retrieved September 1, as negative control while inflammation of the liver,
2018 group 5 was spleen, lungs, kidneys
administered with 100 and brain.
mg/kg of silymarin
orally. Drugs were With high dose of the
administered on extract, the spleen and
alternate days for 28 lungs showed moderate
days at 09.00 am. inflammation. The lungs
also showed moderate
An autopsy was interstitial fibrosis.
performed during which
any macroscopic The plant has a potential
abnormalities were to damage the lungs
noted. The brain, heart, when used on the
liver, spleen, kidney and long term. Its use as
lungs were weighed herbal remedy should
immediately after be for short periods at a
removal. Samples of time.
these organs were fixed
in 10% formalin and kept
in that solution for further
histopathological
examination.
One-Way ANOVA
followed by Tukey
Kramer multiple
comparison post-test
Major objectives/ Delineated Factors/ Methods, Data
Bibliography Central objective/Main Variables/Main Gathering, Tool, Major Finding
objective problem Subjects/ Participants
Bahuguna, A., Khan, I., The main objective of MTT Assay The preparation of the MTT is water-soluble
Bajpai, V., & Kang, S. this study is to materials and that is taken up by the
(2017, April 8). MTT investigate MTT Assay equipment for MTT viable cell. The
assay to evaluate the as a means of Assay. reduction product of
cytotoxic potential of a evaluating the cytotoxic MTT is a water-insoluble
drug. Bangladesh J potential of a drug. Following the protocol of blue formazan, that
Pharmacol. doi: MTT assay as shown in must be dissolved for
10.3329/bjp.v12i2.30892 a schematic calorimetric
representation. measurement. Ethanol,
propanol, acid-
isopropanol, acid-
isopropanol plus 10%
Triton X-100, mineral oil
(unspecified), or DMSO
have all been
suggested. DMSO is
found to be the most
satisfactory.
The study proved that
MTT is more suitable in
assessing the anti-
inflammatory and anti-
cancer activities of any
test samples at
preliminary levels.
Major objectives/ Delineated Factors/ Methods, Data
Bibliography Central objective/Main Variables/Main Gathering, Tool, Major Finding
objective problem Subjects/ Participants
Iberahim, R., Yaacob, The present study is Eleusine indica Whole dried plants were Methanol is a less
W., & Ibrahim, N. (2016, aimed at determining macerated with polar solvent compared
August 20). phytochemical methanol for crude to water thus lesser
Phytochemistry, constituents, cytotoxicity extract preparation and ability for the
Cytotoxicity and Antiviral and antiviral activities for hexane used for phytochemical to be
Activity of Eleusine both crude extract and fractionation. extracted.
indica (Sambau). fraction obtained from
Retrieved September 1, the plant, Eleusine MTT Assay for As for hexane fraction, a
2018 indica. cytotoxicity screening of few secondary
the plant extract against metabolites such as
Vero cells. tannin, alkaloids and
steroid were extracted.
The crude extract
contained more
secondary metabolites
due to high polar
compounds contain in
E. indica.
The crude extract and
hexane fraction
prepared from Eleusine
indica contains antiviral
active compounds and
could be a potential
antiviral agent.
