Material Safety Data Sheet
AvicelÒ RC 591 Stabilizer
MSDS #: 129-B
Revision Date: 2013-08-28
Version 1
FMC BioPolymer
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This MSDS has been prepared to meet U.S. OSHA Hazard Communication Standard 29 CFR 1910.1200
And Canadian Workplace Hazardous Materials Information System (WHMIS) requirements.
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1. PRODUCT AND COMPANY IDENTIFICATION
Product name AvicelÒ RC 591 Stabilizer
Synonyms Microcrystalline cellulose (INCI Name): MCC, cellulose gel; Sodium Carboxymethylcellulose:
NaCMC, CMC, SCMC, Carboxymethyl ether, Sodium CMC, Sodium salt, Cellulose gum,
Carboxymethyl ether, Sodium CMC, Sodium salt, Cellulose gum
Chemical Family Carbohydrate, Cellulose Derivative
Recommended use: Foodstuff application.
Manufacturer Emergency telephone number
FMC BioPolymer 1 302 / 451-0100 (FMC Plant - Newark, Delaware)
1735 Market Street 1 303 / 595 9048 (Medical - U.S. - Call Collect)
Philadelphia, PA 19103
(800) 526-3649 For leak, fire, spill or accident emergencies, call:
msdsinfo@[Link] 1 800 / 424 9300 (CHEMTREC - U.S.A.)
1 703 / 527 3887 (CHEMTREC - Collect - All Other Countries)
2. HAZARDS IDENTIFICATION
Emergency Overview
Dry or powdered ingredients are combustible. Dispersal of finely divided dust from products into air may form mixtures that
are ignitable and explosive. Minimize airborne dust generation and eliminate sources of ignition. May cause skin irritation
and/or dermatitis.
Appearance free flowing powder
Physical state solid
Odor odorless
Eyes May cause slight irritation.
Skin May cause irritation.
Inhalation Inhalation of dust in high concentration may cause irritation of respiratory system.
Ingestion Ingestion may cause gastrointestinal discomfort including nausea, vomiting and diarrhea if large
amounts are ingested. Potential for aspiration if swallowed. No known effect based on information
supplied.
Aggravated Medical Conditions Respiratory disorders.
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AvicelÒ RC 591 Stabilizer MSDS #: 129-B
Revision Date: 2013-08-28
Version 1
3. COMPOSITION/INFORMATION ON INGREDIENTS
Non-Hazardous
Chemical Name CAS-No
Microcrystalline cellulose 9004-34-6
Sodium carboxymethylcellulose 9004-32-4
4. FIRST AID MEASURES
Eye contact Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. Get medical
attention immediately if symptoms occur.
Skin contact Wash with water and soap as a precaution.
Inhalation Move to fresh air. If breathing is irregular or stopped, administer artificial respiration. Consult a
physician.
Ingestion Never give anything by mouth to an unconscious person. Drink plenty of water. Get medical
attention immediately if symptoms occur.
Indication of immediate medical Treat symptomatically.
attention and special treatment needed,
if necessary
Protection of first-aiders Use personal protective equipment.
5. FIRE-FIGHTING MEASURES
Flash Point Not applicable
Suitable extinguishing media Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Specific hazards arising from the Avoid dust formation. Dusts or fumes may form explosive mixtures in air.
chemical
Protective equipment and precautions As in any fire, wear self-contained breathing apparatus pressure-demand, MSHA/NIOSH (approved
for firefighters or equivalent) and full protective gear.
NFPA
Health Hazard 0
Flammability 1
Stability 0
Special Hazards -
6. ACCIDENTAL RELEASE MEASURES
Personal precautions Wear personal protective equipment. Avoid contact with the skin and the eyes. Avoid dust
formation. For personal protection see section 8.
Methods for containment Maintain good housekeeping practices to avoid accumulation of settled dust, especially on overhead
surfaces.
Methods for cleaning up Sweep or vacuum up spillage and return to container. Washdown water is not recommended.
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AvicelÒ RC 591 Stabilizer MSDS #: 129-B
Revision Date: 2013-08-28
Version 1
7. HANDLING AND STORAGE
Handling Avoid dust formation. Avoid contact with skin, eyes and clothing. Wear personal protective
equipment. Refer to Section 8.
Storage Keep containers tightly closed in a dry, cool and well-ventilated place. Keep away from heat.
8. Exposure controls/personal protection
Exposure guidelines
Chemical Name ACGIH TLV OSHA PEL NIOSH Mexico
Microcrystalline cellulose TWA: 10 mg/m3 TWA: 15 mg/m3 TWA: 5 TWA: 10 mg/m3 TWA: 5
9004-34-6 mg/m3 mg/m3
Chemical Name British Columbia Quebec Ontario TWAEV Alberta
Microcrystalline cellulose TWA: 10 mg/m3 TWA: 10 mg/m3 TWA: 10 mg/m3 TWA: 10 mg/m3
9004-34-6 TWA: 3 mg/m3
Occupational exposure controls
Engineering measures Apply technical measures to comply with the occupational exposure limits.
Personal Protective Equipment
General Information If the product is used in mixtures, it is recommended that you contact the appropriate protective
equipment suppliers. These recommendations apply to the product as supplied.
Respiratory protection In case of insufficient ventilation wear suitable respiratory equipment.
Eye/face protection Safety glasses.
Skin and body protection No special precautions required.
Hand protection No special precautions required. Please observe the instructions regarding permeability and
breakthrough time which are provided by the supplier of the gloves. Also take into consideration the
specific local conditions under which the product is used, such as the danger of cuts, abrasion If used
in solution, or mixed with other substances, and under conditions which differ from EN 374, contact
the supplier of the EC approved gloves
Hygiene measures When using, do not eat, drink or smoke. Wear suitable gloves and eye/face protection. Wash hands
before breaks and at the end of workday.
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AvicelÒ RC 591 Stabilizer MSDS #: 129-B
Revision Date: 2013-08-28
Version 1
9. PHYSICAL AND CHEMICAL PROPERTIES
Appearance free flowing powder
Color off-white
Physical state solid
Odor odorless
Odor Threshold No information available.
pH (in solution) 6.0 - 8.0 (2% solids dispersion)
Melting Point/Range not determined
Freezing point No information available.
Boiling Point/Range No information available.
Flash Point Not applicable
Evaporation rate No information available.
Autoignition Temperature Not applicable
Vapor pressure Not applicable
Vapor density No information available.
Density No information available
Specific Gravity No information available.
Bulk density 0.6 g/cc
Water solubility Dispersible in water
Percent volatile 4 % water, by weight
Partition coefficient: No information available.
Viscosity No information available.
Oxidizing properties Not applicable
10. STABILITY AND REACTIVITY
Stability Stable.
Conditions to avoid Excessive heat. Dust formation.
Hazardous decomposition products None under normal use.
Hazardous polymerization Hazardous polymerization does not occur.
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AvicelÒ RC 591 Stabilizer MSDS #: 129-B
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11. TOXICOLOGICAL INFORMATION
Acute Toxicity This product is expected to have low oral, dermal and inhalation toxicity.
Skin contact Non-irritating (rabbit). (Primary Irritation Index (PII)= 0.8).
Eye contact Non-irritating (rabbit).
Inhalation May cause irritation of respiratory tract.
Ingestion May cause gastrointestinal discomfort if consumed in large amounts. Potential for aspiration if
swallowed.
Component Information
Chemical Name LD50 Oral LD50 Dermal LC50 Inhalation
Microcrystalline cellulose 5 g/kg ( Rat ) 2 g/kg ( Rabbit ) >5800 mg/m3 ( Rat ) 4 h
Sodium carboxymethylcellulose 27000 mg/kg ( Rat ) >2 g/kg ( Rabbit ) >5800 mg/m3 ( Rat ) 4 h
Chronic Toxicity
Chronic Toxicity No known effect based on information supplied.
Carcinogenicity Contains no ingredient listed as a carcinogen.
Sensitization Not expected to be sensitizing based on the components.
Developmental Toxicity No information available.
Teratogenicity No information available.
Target Organ Effects Respiratory system.
12. ECOLOGICAL INFORMATION
Ecotoxicity
The environmental impact of this product has not been fully investigated.
Microcrystalline cellulose (9004-34-6)
Active Ingredient(s) Duration Species Value Units:
Microcrystalline cellulose 48 h LC50 Daphnia > 100% saturated solution
Microcrystalline cellulose 96 h LC50 Rainbow trout > 100% saturated solution
Microcrystalline cellulose 96 h EC50 Algae > 100% saturated solution
Persistence and degradability No product level data available. Microcrystalline cellulose is inherently biodegradable in soil.
Microcrystalline cellulose biodegrades in soil at a rate comparable to corn starch.
Bioaccumulation Bioaccumulation is unlikely.
Mobility No information available.
Other adverse effects None known
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AvicelÒ RC 591 Stabilizer MSDS #: 129-B
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13. DISPOSAL CONSIDERATIONS
Waste disposal methods This material, as supplied, is not a hazardous waste according to Federal regulations (40 CFR 261).
This material could become a hazardous waste if it is mixed with or otherwise comes in contact with
a hazardous waste, if chemical additions are made to this material, or if the material is processed or
otherwise altered. Consult 40 CFR 261 to determine whether the altered material is a hazardous
waste. Consult the appropriate state, regional, or local regulations for additional requirements.
Contaminated packaging Dispose of in accordance with local regulations.
14. Transport information
DOT not regulated
TDG not regulated
ICAO/IATA not regulated
IMDG/IMO not regulated
15. REGULATORY INFORMATION
International Inventories
Chemical Name TSCA DSL EINECS/E ENCS IECSC KECL PICCS AICS NZIoC
Inventory (Canada) LINCS (Japan) (China) (Korea) (Philippines (Australia) (New
(United (Europe) ) Zealand)
States of
America)
Microcrystalline - X - X X X X - X
cellulose
9004-34-6
Sodium - X - X X X X - X
carboxymethylcellulose
9004-32-4
Legend: X - Listed
U.S. Federal Regulations
SARA 313
Section 313 of Title III of the Superfund Amendments and Reauthorization Act of 1986 (SARA). This product does not contain any chemicals
which are subject to the reporting requirements of the Act and Title 40 of the Code of Federal Regulations, Part 372.
SARA 311/312 Hazard Categories
Acute Health Hazard no
Chronic Health Hazard no
Fire Hazard no
Sudden Release of Pressure Hazard no
Reactive Hazard no
CERCLA
This material, as supplied, does not contain any substances regulated as hazardous substances under the Comprehensive Environmental
Response Compensation and Liability Act (CERCLA) (40 CFR 302) or the Superfund Amendments and Reauthorization Act (SARA) (40 CFR
355). There may be specific reporting requirements at the local, regional, or state level pertaining to releases of this material.
International Regulations
Mexico - Grade Minimum risk, Grade 0
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AvicelÒ RC 591 Stabilizer MSDS #: 129-B
Revision Date: 2013-08-28
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Canada
This product has been classified in accordance with the hazard criteria of the Controlled Products Regulations (CPR) and the MSDS
contains all the information required by the CPR.
WHMIS Hazard Class
Non-controlled
16. OTHER INFORMATION
HMIS Health Hazard 0 Flammability 1 Stability 0 Special precautions -
NFPA/HMIS Ratings Legend Severe = 4; Serious = 3; Moderate = 2; Slight = 1; Minimal = 0
Revision Date: 2013-08-28
Reason for revision: No information available.
Disclaimer
FMC Corporation believes that the information and recommendations contained herein (including data and statements) are accurate as of the date
hereof. NO WARRANTY OF FITNESS FOR ANY PARTICULAR PURPOSE, WARRANTY OF MERCHANTABILITY OR ANY OTHER
WARRANTY, EXPRESSED OR IMPLIED, IS MADE CONCERNING THE INFORMATION PROVIDED HEREIN. The information provided
herein relates only to the specified product designated and may not be applicable where such product is used in combination with any other materials or
in any process. Further, since the conditions and methods of use are beyond the control of FMC Corporation, FMC corporation expressly disclaims any
and all liability as to any results obtained or arising from any use of the products or reliance on such information.
Prepared By
Avicel and FMC BioPolymer Logo - Trademarks of FMC Corporation
© 2013 FMC Corporation. All Rights Reserved.
End of Material Safety Data Sheet
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