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Bioenergetics Syllabus

This bioenergetics syllabus covers fundamental concepts like free energy and how it relates to equilibrium constants in coupled reactions and high-energy compounds. It discusses biological oxidation reactions and how reduction potentials are measured and used to calculate free energy changes, as well as the enzymes involved in oxidation and reduction. It also examines the mitochondrial electron transport chain, including the transport systems, components, electron flow, sites of ATP production, inhibitors, coupling of oxidation and phosphorylation via the chemiosmotic hypothesis, and the mechanism of ATP synthesis.

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Kamlesh Sahu
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228 views1 page

Bioenergetics Syllabus

This bioenergetics syllabus covers fundamental concepts like free energy and how it relates to equilibrium constants in coupled reactions and high-energy compounds. It discusses biological oxidation reactions and how reduction potentials are measured and used to calculate free energy changes, as well as the enzymes involved in oxidation and reduction. It also examines the mitochondrial electron transport chain, including the transport systems, components, electron flow, sites of ATP production, inhibitors, coupling of oxidation and phosphorylation via the chemiosmotic hypothesis, and the mechanism of ATP synthesis.

Uploaded by

Kamlesh Sahu
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as DOCX, PDF, TXT or read online on Scribd

Bioenergetics Syllabus

Bioenergetics: Concept of Free energy; standard Free energy; Relationship between


standard free-energy change and equilibrium constant; Coupled reactions; High-energy
compounds. Biological oxidation: Oxidation & reduction; Oxidation-reduction half reactions;
Nernst equation, measurement of standard reduction potentials; Calculation of G from
standard reduction potentials; Enzymes involved in oxidation and reduction (oxidases,
dehydrogenases, hydroperoxidases and oxygenases). Introduction to Metabolism and
Experimental approaches for studying metabolism.
Mitochondrial Electron Transport Chain and Oxidative Phosphorylation: Mitochondrial
Transport Systems; Nature, order and organization of the components of electron transport
chain; electron flow from NADH and FADH2 to O2; sites of ATP production; inhibitors of
electron transport chain; Coupling between oxidation and phosphorylation; Chemiosmotic
hypothesis of oxidative phosphorylation; Mechanism of ATP synthesis: Structure of proton-
translocating ATP synthase; Binding Change Mechanism for proton-driven ATP synthesis;
Uncoupling of oxidative phosphorylation; Control of oxidative phosphorylation.

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