OUR LADY OF FATIMA UNIVERSITY
College of Pharmacy – Antipolo Campus
Pharmacology 2 with Therapeutics (PHA414)
SEATWORK on DIABETES MELLITUS
Name: Yr./Sec.: Date:
INSTRUCTIONS: Complete the following sentences and answer the follow-up questions. Prepare for a quiz next meeting.
1. The hormone insulin is secreted in the ________ 6. Type 4 diabetes mellitus or gestational diabetes
of the islet of Langerhans in the ________. What is the hyperglycemia associated with _________.
are the other cells in the islets and what are their Define Type 1, 2, and 3 diabetes mellitus.
secretory products?
7. The most common extensive effect of insulin is
2. The normal range for fasting blood sugar (FBS) is _____________. What are the other adverse
______ mg/dL. Aside from FBS, enumerate five drug effects of insulin?
(5) other diagnostic tool for diabetes mellitus.
8. Insulin releasers like sulfonylurea and
3. Glycogenolysis is the breakdown of meglitinides are also known as ______________.
___________ to form ____________. Define What are the mechanisms of action of both group
glycogenesis, glycolysis, and gluconeogenesis. of drugs?
4. Bovine and porcine insulins are immunogenic 9. ____________ agents are anti-diabetic drugs
insulin extracted from ________ and _________, that normalize blood glucose. Give two groups
respectively. What are the other sources of classified as such and their mechanisms of
insulin? action.
5. Regular insulin has a ______ onset of action and 10. Exenatide is classified as _______________ and
_____ duration of action. Tabulate the different Sitagliptin is classified as _______________.
types of insulin according to duration and onset. Draw a diagram showing their mechanisms of
action.