Khan Academy Cell-Cell Interactions E.
Which signaling molecule is LEAST
Questions likely to serve as a ligand for an
intracellular receptor?
1. Extracellular fluids are LEAST likely to
move through the space between cells A. Growth hormone
that are joined by which type of B. Ethylene
intercellular junction? C. Nitric oxide
D. Estrogen
A. Desmosome
B. Tight Junction 5. Which statement represents a key
C. Macula adherens difference between a G protein-coupled
D. Gap junction receptor and a receptor tyrosine kinase?
2. In cardiac muscle tissue, what is the A. A G protein-coupled receptor can be
primary purpose of intercalated discs? activated by a diverse array of
ligands.
A. Depolarization and repolarization of B. A receptor tyrosine kinase acts as
cells an enzyme to its intracellular
B. Generating electrical impulses in substrate.
cells C. A single ligand can activate multiple
C. Permitting the passage of ions signal transduction pathways
between cells through a receptor tyrosine kinase.
D. Preventing separation of muscle D. A receptor tyrosine kinase is more
cells during contraction likely to activate gene transcription.
3. What is the correct order of steps in a 6. When acetylcholine binds to its receptor
common G-Protein coupled receptor on a neuron, Na+ rushes into/out of the
(GPCR) signal transduction? The cell. Which type of receptor is this an
answer does not include all steps. example of?
I. Formation of ligand-receptor complex A. Voltage-gated ion channel
II. Release of neurotransmitter into B. Nicotinic receptor
synapse C. Ligand-gated ion channel
III. Alpha subunit regulates target D. Muscarinic receptor
protein
IV. Intracellular phosphorylation 7. In the following epinephrine pathway,
which component is the second
cascade
messenger?
V. G protein acquires GTP
VI. Dissociation of G protein subunits Epinephrine → G protein-coupled
VII. Cross-phosphorylation of G proteins receptor → G protein → adenylyl
VIII. Hormone binds to GPCR cyclase → cAMP → protein kinase
A. I, V, III, IV, VI A. G Protein
B. I, V, III, IV, VI B. cAMP
C. I, V, III, IV, VI C. GTP
D. I, V, III, IV, VI D. Adenylyl cyclase
4. Which type of membrane receptor
protein best describes receptor tyrosine
kinases?.
A. Ligand-gated ion channel
B. Enzyme-linked receptor
C. G-Protein coupled receptor
D. Intracellular receptor
8. A researcher plans to determine the rate
of diffusion of a substance across a
plasma membrane by measuring how
quickly it moves across a single layer of
cells. Which type of cellular junction will
best accommodate her experiment?
A. Intercalated discs
B. Gap junctions
C. Desmosomal adhesion
D. Tight junctions
9. Steroid hormones such as testosterone
and estrogen act on target cells by
passing directly through the cell
membrane. If steroid hormones can
enter any cell, how do they only produce
an effect in target cells?
A. Only target cells contain the
enzymes to appropriately modify
steroid hormones.
B. Only in target cells can testosterone
initiate the proper phosphorylation
cascade.
C. Only target cells retain the
necessary genes for the steroid to
act on.
D. Only target cells possess the proper
intracellular receptor.
Khan Academy Cell-Cell Interactions
Answers
1. B
2. C
3. B
4. B
5. A
6. B
7. C
8. B
9. D
10. D
