Scribd
Upload
254 views7 pages

FM-200 Material Safety Data Sheet

This document provides a material safety data sheet for FM-200, which is a registered trademark of DuPont. The MSDS summarizes key information about the product including its composition, hazards, safe handling procedures, and emergency response measures. FM-200 is not flammable but may decompose to form toxic gases when exposed to high heat or flames. Personal protective equipment including respirators and protective clothing are recommended when handling the product. Animal studies found no toxic effects at certain exposure levels but cardiac sensitization was observed in dogs at high concentrations.

Uploaded by

Mohd A Ishak
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as PDF, TXT or read online on Scribd
254 views7 pages

FM-200 Material Safety Data Sheet

This document provides a material safety data sheet for FM-200, which is a registered trademark of DuPont. The MSDS summarizes key information about the product including its composition, hazards, safe handling procedures, and emergency response measures. FM-200 is not flammable but may decompose to form toxic gases when exposed to high heat or flames. Personal protective equipment including respirators and protective clothing are recommended when handling the product. Animal studies found no toxic effects at certain exposure levels but cardiac sensitization was observed in dogs at high concentrations.

Uploaded by

Mohd A Ishak
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as PDF, TXT or read online on Scribd

The MSDS format adheres to the standards and regulatory requirements

of the United States and may not meet regulatory requirements


in other countries.

DuPont Page 1
Material Safety Data Sheet

----------------------------------------------------------------------
FM-200
6402FR Revised 28-FEB-2008
----------------------------------------------------------------------
----------------------------------------------------------------------
CHEMICAL PRODUCT/COMPANY IDENTIFICATION
----------------------------------------------------------------------
Material Identification

FM-200 is a registered trademark of DuPont.

CAS Number : 431-89-0


Formula : CF3 CHF CF3
Molecular Weight : 170.03
CAS Name : Propane, 1,1,1,2,3,3,3-Heptafluoro-

Tradenames and Synonyms

FM200
FE-227
2-Hydroperfluoropropane
Propane, 1,1,1,2,3,3,3-Heptafluoro-
HFC-227eaHP
2-Hydroheptafluoropropane
Heptafluoropropane
2-H-heptafluoropropane
1,1,1,2,3,3,3-Heptafluoropropane
R-227
R227
HFC-227ea

Company Identification

MANUFACTURER/DISTRIBUTOR
DuPont Fluoroproducts
1007 Market Street
Wilmington, DE 19898

PHONE NUMBERS
Product Information : 1-800-441-7515 (outside the U.S.
302-774-1000)
Transport Emergency : CHEMTREC 1-800-424-9300(outside U.S.
703-527-3887)
Medical Emergency : 1-800-441-3637 (outside the U.S.
302-774-1000)

----------------------------------------------------------------------
COMPOSITION/INFORMATION ON INGREDIENTS
----------------------------------------------------------------------
Components

Material CAS Number %


1,1,1,2,3,3,3-Heptafluoropropane 431-89-0 99.95
6402FR DuPont Page 2
Material Safety Data Sheet

----------------------------------------------------------------------
HAZARDS IDENTIFICATION
----------------------------------------------------------------------
Potential Health Effects

Based on animal data, overexposure to FM-200 by inhalation


may cause suffocation, if air is displaced by vapors, and
irregular heart beat with a strange sensation in the chest,
"heart thumping," apprehension, lightheadedness, feeling of
fainting, dizziness, weakness, sometimes progressing to loss
of consciousness and death.

FM-200 may cause frostbite if liquid or escaping vapor


contacts the skin.

FM-200 may cause "frostbite-like" effects if the liquid


or escaping vapors contact the eyes.

In one study, human volunteers were selected to inhale


FM-200 at a concentration of 6000 ppm but the study was
terminated due to a rise in pulse rate that was believed to
be unrelated to the chemical. In a subsequent study with
human volunteers inhaling concentrations up to 8000 ppm no
clinically significant effects were observed for any of the
measured laboratory parameters.

Individuals with preexisting diseases of the cardiovascular


system or nervous system may have increased susceptibility
from excessive exposures.

Carcinogenicity Information

None of the components present in this material at concentrations


equal to or greater than 0.1% are listed by IARC, NTP, OSHA or ACGIH
as a carcinogen.

----------------------------------------------------------------------
FIRST AID MEASURES
----------------------------------------------------------------------
First Aid

INHALATION

If inhaled, immediately remove to fresh air. If not breathing,


give artificial respiration. If breathing is difficult, give
oxygen. Call a physician.

SKIN CONTACT

Treat for frostbite if necessary by gently warming affected area.

EYE CONTACT

In case of contact, immediately flush eyes with plenty of water


for at least 15 minutes. Call a physician.
6402FR DuPont Page 3
Material Safety Data Sheet

(FIRST AID MEASURES - Continued)

INGESTION

Ingestion is not considered a potential route of exposure.

----------------------------------------------------------------------
FIRE FIGHTING MEASURES
----------------------------------------------------------------------
Flammable Properties

1,1,1,2,3,3,3-Heptafluoropropane is not flammable, however


in the presence of a flame or ignition source it may
decompose to form toxic hydrogen fluoride or carbonyl
fluoride.

Non-flammable.

Extinguishing Media

Use media appropriate for surrounding material.

Fire Fighting Instructions

Self-contained breathing apparatus (SCBA) may be required if


cylinders rupture or release under fire conditions.

Keep cylinders cool with water spray applied from a safe


distance.

----------------------------------------------------------------------
ACCIDENTAL RELEASE MEASURES
----------------------------------------------------------------------
Safeguards (Personnel)

NOTE: Review FIRE FIGHTING MEASURES and HANDLING (PERSONNEL)


sections before proceeding with clean-up. Use appropriate
PERSONAL PROTECTIVE EQUIPMENT during clean-up.

Evacuate personnel, thoroughly ventilate area, use self-contained


breathing apparatus. Keep upwind of leak - evacuate until gas has
dispersed.

Initial Containment

Use forced ventilation to disperse vapors.


6402FR DuPont Page 4
Material Safety Data Sheet

----------------------------------------------------------------------
HANDLING AND STORAGE
----------------------------------------------------------------------
Handling (Personnel)

Do not breathe gas. Avoid contact with eyes, skin, or clothing.


Wash thoroughly after handling. Wash clothing after use.

Storage

Store in a clean, dry place. Store below 52 C (126 F).

----------------------------------------------------------------------
EXPOSURE CONTROLS/PERSONAL PROTECTION
----------------------------------------------------------------------
Engineering Controls

Use only with adequate ventilation. Keep container tightly closed.

Personal Protective Equipment

EYE/FACE PROTECTION

Wear safety glasses or coverall chemical splash goggles.

RESPIRATORS

Wear NIOSH approved respiratory protection, as appropriate.

PROTECTIVE CLOTHING

Where there is potential for skin contact have available and wear
as appropriate impervious gloves, apron, pants, and jacket.

Exposure Guidelines

Exposure Limits
FM-200
AEL * (DuPont) : 1000 ppm, 8 & 12 Hr. TWA

* AEL is DuPont’s Acceptable Exposure Limit. Where governmentally


imposed occupational exposure limits which are lower than the AEL
are in effect, such limits shall take precedence.

----------------------------------------------------------------------
PHYSICAL AND CHEMICAL PROPERTIES
----------------------------------------------------------------------
Physical Data

Boiling Point : -16.4 C (2.5 F)


Melting Point : -131 C (-204 F)
Vapor Pressure : 65.7 psia @ 25 C (77 F) (453.3 kPa)
Liquid Density : 1.386 g/cm3 @ 25 C (77 F) (86.53 lb/ft3)
Critical temperature : 101.6 C (214.9 F)
Critical pressure : 424.7 psia (2930 kPa)
Odor : None.
6402FR DuPont Page 5
Material Safety Data Sheet

(PHYSICAL AND CHEMICAL PROPERTIES - Continued)

Form : Liquified Gas

----------------------------------------------------------------------
STABILITY AND REACTIVITY
----------------------------------------------------------------------
Chemical Stability

Stable at normal temperatures and storage conditions.

Avoid sources of heat or open flame.

Incompatibility with Other Materials

Incompatible with strong reducing agents such as alkali


metals (e.g., sodium, potassium), alkali-earth metals (e.g.,
magnesium, calcium), and powdered aluminum or zinc.

Decomposition

Decomposes by reaction with high temperature (open flames,


glowing metal surfaces, etc.) forming hydrofluoric acid,
carbonyl fluorides, carbon monoxide and carbon dioxide.

Polymerization

Polymerization will not occur.

----------------------------------------------------------------------
TOXICOLOGICAL INFORMATION
----------------------------------------------------------------------
Animal Data

FM-200:

Inhalation 4 hour LC50: > 788,698 ppm in rats

Repeated exposure of rats by inhalation for 4 weeks at


concentrations up to 50,000 ppm revealed no toxicologically
significants effects. The NOEL for this study was 50,000
ppm. A 90-day inhalation study in rats did not find any
exposure related effects at 105,000 ppm. The NOEL for this
study was 105,000 ppm.

Cardiac sensitization, a potentially fatal disturbance of


heart rhythm associated with a heightened sensitivity to the
action of epinephrine, occurred in dogs at 105,000 ppm. The
NOAEL for cardiac sensitization was 90,000 ppm. In a
different study to evaluate cardiac sensitization in dogs,
concentrations of 90,000, 105,000, and 140,000 ppm caused a
dose-related increase in incidence and severity; at 90,000
ppm efffects were minimal or mild in nature.

Inhalation studies in rabbits and rats do not


suggest developmental toxicity at concentrations up to
6402FR DuPont Page 6
Material Safety Data Sheet

(TOXICOLOGICAL INFORMATION - Continued)

105,000 ppm. Tests have shown that FM-200 does not cause
genetic damage in bacterial or mammalian cell cultures.
Tests in animals for carcinogenicity or reproductive
toxicity have not been conducted.

----------------------------------------------------------------------
DISPOSAL CONSIDERATIONS
----------------------------------------------------------------------
Waste Disposal

Treatment, storage, transportation, and disposal must be in


accordance with applicable Federal, State/Provincial, and Local
regulations. Incinerate material in accordance with Federal,
State/Provincial and Local requirements.

----------------------------------------------------------------------
TRANSPORTATION INFORMATION
----------------------------------------------------------------------
Shipping Information

DOT
Proper Shipping Name : Heptafluoropropane
Hazard Class : 2.2
I.D. No. (UN/NA) : UN 3296
DOT Label(s) : Nonflammable Gas

----------------------------------------------------------------------
REGULATORY INFORMATION
----------------------------------------------------------------------
U.S. Federal Regulations

TSCA Inventory Status : Listed.

TITLE III HAZARD CLASSIFICATIONS SECTIONS 311, 312

Acute : Yes
Chronic : No
Fire : No
Reactivity : No
Pressure : No

----------------------------------------------------------------------
OTHER INFORMATION
----------------------------------------------------------------------
NFPA, NPCA-HMIS

NFPA Rating
Health : 1
Flammability : 0
Reactivity : 1

NPCA-HMIS Rating
Health : 1
Flammability : 0
6402FR DuPont Page 7
Material Safety Data Sheet

(Continued)

Reactivity : 0

Personal Protection rating to be supplied by user depending on use


conditions.

----------------------------------------------------------------------

The data in this Material Safety Data Sheet relates only to the
specific material designated herein and does not relate to use in
combination with any other material or in any process.

Responsibility for MSDS : MSDS Coordinator


> : DuPont Fluoroproducts
Address : Wilmington, DE 19898
Telephone : (800) 441-7515

This information is based upon technical information believed to be


reliable. It is subject to revision as additional knowledge and
experience is gained.

End of MSDS

Common questions

Powered by AI

FM-200’s classification as a nonflammable gas influences its handling and transportation under the DOT classification. It is labeled with a hazard class of 2.2 and identified as a nonflammable gas (UN 3296), indicating it poses minimal flammability risk but requires precautionary measures against pressure and release .

Overexposure to FM-200 by inhalation might cause suffocation due to displacement of air by vapors, as well as an irregular heartbeat characterized by a sensation of 'heart thumping,' apprehension, lightheadedness, and dizziness, which can progress to a loss of consciousness and death. These effects occur if the air is displaced by vapors in confined spaces .

Safe handling procedures, such as avoiding inhalation and skin contact, are linked to FM-200’s capacity to cause suffocation, frostbite, and cardiac sensitization if mishandled. Furthermore, the requirement to store FM-200 below 52°C ensures stability and prevents its decomposing under heat to form hazardous compounds like hydrofluoric acid .

DuPont's Acceptable Exposure Limit (AEL) for FM-200 is set at 1000 ppm for both 8-hour and 12-hour time-weighted averages. This might differ from other governmental limits because the AEL reflects DuPont’s internal safety standards, which may take into consideration proprietary data or specific workplace conditions unknown to governmental agencies. However, governmental limits will take precedence if they are lower, indicating they may incorporate broader health safety data or different population safety margins .

Individuals with preexisting cardiovascular conditions may experience heightened susceptibility to FM-200 exposure due to its potential to disrupt heart rhythms at high concentrations and cause cardiac sensitization. This increased risk underscores the necessity for stringent exposure controls and monitoring for vulnerable populations within work environments .

FM-200 is stable at normal temperatures and storage conditions, particularly when kept away from sources of heat or open flame . This highlights the importance of the recommended storage conditions to prevent decomposition into toxic compounds such as hydrofluoric acid, carbonyl fluorides, carbon monoxide, and carbon dioxide .

Animal studies have not been conducted specifically for the carcinogenicity of FM-200. However, tests have shown that FM-200 does not cause genetic damage in bacterial or mammalian cell cultures, suggesting a low likelihood of FM-200 being genotoxic .

Being listed on the TSCA inventory ensures that FM-200 has been reviewed for compliance with EPA regulations, facilitating better regulatory oversight. This status implies that manufacturers must comply with reporting and recordkeeping requirements, reflecting a systematic evaluation of FM-200's environmental and health impacts, thereby enhancing product safety .

Essential engineering controls when working with FM-200 include adequate ventilation to prevent the buildup of vapors and maintaining containers tightly closed. These measures are critical to avoid inhalation hazards and ensuring air quality is kept within safe exposure limits .

During FM-200 spill cleanup, personnel should use appropriate personal protective equipment, evacuate the area, and ensure thorough ventilation. Additionally, individuals should use self-contained breathing apparatus and remain upwind of any leak to avoid inhalation of harmful vapors .

You might also like