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Amlodipine and Atorvastatin Drug Study

This document summarizes a drug study for a 77-year-old patient taking amlodipine for hypertension. Amlodipine is a calcium channel blocker typically taken once daily to manage hypertension and coronary artery disease by dilating blood vessels. Common side effects include peripheral edema, headache, flushing, and dizziness. Nursing responsibilities include monitoring the patient's blood pressure, checking for side effects like peripheral edema, and teaching the patient about compliance, avoiding abrupt discontinuation, and not consuming grapefruit products while taking amlodipine.

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0% found this document useful (0 votes)
809 views4 pages

Amlodipine and Atorvastatin Drug Study

This document summarizes a drug study for a 77-year-old patient taking amlodipine for hypertension. Amlodipine is a calcium channel blocker typically taken once daily to manage hypertension and coronary artery disease by dilating blood vessels. Common side effects include peripheral edema, headache, flushing, and dizziness. Nursing responsibilities include monitoring the patient's blood pressure, checking for side effects like peripheral edema, and teaching the patient about compliance, avoiding abrupt discontinuation, and not consuming grapefruit products while taking amlodipine.

Uploaded by

Maurice
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as DOCX, PDF, TXT or read online on Scribd
  • Clinical Record - Entry 1
  • Clinical Record - Entry 2

UNIVERSITY OF CEBU-BANILAD

COLLEGE OF NURSING

DRUG STUDY

Patient: B.R Age: 77 years old Hospital No. 293998 Room No. 711

Impression/Diagnosis: Acute parenchymal bleed, left middle cerebellar area sepsis to secondary to diabetic foot Attending Physician(s): Dr. Romero, Chela Marie
Tanato

Allergy to: None

Generic/ Brand Name & Dosage Timing & Duration Indication/Pharmacodynamics of Drug Side Effects/ Adverse Nursing Responsibilities Patient Teaching
Classification Reaction/ Contraindication
(5%) (20%) (Nursing Process Approach) (20 %)
(5%) (10%)
(40%)

Generic Name: Drug form & Dosage Indications: Side Effects: Assessment  Do not abruptly
Ordered: discontinue medication.
Amlodipine Management of hypertension, coronary artery Frequent (greater than 5%):  Assess baseline
 Compliance with therapy
10 mg/tab disease (chronic stable angina, vasospastic Peripheral edema, headache, renal/hepatic function tests,
regimen is essential to
[Prinzmetal’s or variant] flushing. B/P, apical pulse.
control hypertension.
(Kizior & Hodgson, 2021) Occasional (5%–1%): Interventions  Avoid tasks that require
Dizziness, palpitations, nausea, alertness, motor skills until
Brand Name: unusual fatigue or weakness  Assess B/P (if systolic B/P response to drug is
Timing: Pharmacodynamics (asthenia). is less than 90 mm Hg, established.
withhold medication,  Do not ingest grapefruit
O.D. Inhibits calcium movement across cardiac and Rare (less than 1%): Chest contact physician).
vascular smooth muscle cell membranes pain, bradycardia, orthostatic products
 Assess for peripheral
during depolarization. hypotension. (Kizior & Hodgson, 2021)
edema behind medial
Classification Name: Therapeutic Effect: Dilates coronary arteries,
Adverse Effects: malleolus (sacral area in
peripheral arteries/arterioles. Decreases total
PHARMACOTHERAPEUTIC: peripheral vascular resistance and B/P by bedridden pts).
Overdose may produce  Assess skin for flushing.
Calcium channel blocker Duration: vasodilation.
excessive peripheral Question for headache,
(dihydropyridine). (Kizior & Hodgson, 2021)
vasodilation, marked asthenia.
CLINICAL: Antihypertensive, hypotension with reflex
antianginal. tachycardia, syncope. (Kizior & Hodgson, 2021)
Pharmacokinetics Contraindication
Route Onset Peak Duration Hypersensitivity to amlodipine
P.O. Unknown 6–12 hr 24 hr or its components

Slowly absorbed from GI tract. Protein (Kizior & Hodgson, 2021)


Other drug forms:
binding: 95%–98%. Metabolized in liver.
Excreted primarily in urine. Not removed by
Tablets: 2.5 mg, 5 mg, 10 mg hemodialysis. Half-life: 30–50 hrs (increased
in elderly, pts with hepatic cirrhosis)

___Sheila K. Maceda, RN, MAN__ _______CLAIRE MAURICE G. JUANERO_____


Printed Name and Signature Printed Name and Signature
Clinical Instructor Student

UNIVERSITY OF CEBU-BANILAD
COLLEGE OF NURSING

DRUG STUDY

Patient: B.R Age: 77 years old Hospital No. 293998 Room No. 711

Impression/Diagnosis: Acute parenchymal bleed, left middle cerebellar area sepsis to secondary to diabetic foot Attending Physician(s): Dr. Romero, Chela Marie
Tanato

Allergy to: None

Generic/ Brand Name & Dosage Timing & Duration Indication/Pharmacodynamics of Drug Side Effects/ Adverse Nursing Responsibilities Patient Teaching
Classification Reaction/ Contraindication
(5%) (20%) (Nursing Process Approach) (20 %)
(5%) (10%)
(40%)

Generic Name: Drug form & Dosage Indications: Side Effects: Assessment  Emphasize that
Ordered: atorvastatin is an adjunct to
Atorvastatin Primary prevention of cardiovascular disease Common: Atorvastatin is  Obtain baseline —not a substitute for—a
40 mg/tab in high-risk pts. Reduces risk of stroke and generally well tolerated. Side cholesterol, triglycerides, low-cholesterol diet.
heart attack A Canadian trade name Non- effects are usually mild and LFT.
 Tell patient to take drug at
Crushable Drug High Alert drug atorvastatin transient.  Obtain dietary history. the same time each day to
Brand Name: 95 in pts with type 2 diabetes with or without
Frequent (16%): Headache. maintain its effects.
evidence of heart disease. Reduces risk of Interventions
stroke in pts with or without evidence of heart  Instruct patient to take a
Occasional (5%–2%): Myalgia,  Monitor for headache.
Timing: disease with multiple risk factors other than missed dose as soon as
rash, pruritus, allergy.  Assess for rash, pruritus,
diabetes. possible. If it’s almost time
O.D. malaise.
Rare (less than 2%–1%): for his next dose, he should
(Kizior & Hodgson, 2021) Flatulence, dyspepsia,  Monitor cholesterol,
Classification Name: skip the missed dose. Tell
triglyceride lab values for
depression. him not to double the dose.
PHARMACOTHERAPEUTIC: therapeutic response.
 Instruct patient to consult
Hydroxymethylglutaryl CoA Adverse Effects:  Monitor LFTs, CPK.
Pharmacodynamics prescriber before taking
(HMG-CoA) reductase Duration: Potential for cataracts, OTC niacin because of
inhibitor. Inhibits HMG-CoA reductase, the enzyme (Kizior & Hodgson, 2021)
photosensitivity, myalgia, increased risk of
that catalyzes the early step in cholesterol
CLINICAL: rhabdomyolysis. rhabdomyolysis.
synthesis. Results in an increase of expression
Antihyperlipidemic.  Advise patient to notify
in LDL receptors on hepatocyte membranes Contraindication
and a stimulation of LDL catabolism. prescriber immediately if
Active hepatic disease, he develops unexplained
Therapeutic Effect: Decreases LDL and
breastfeeding, hypersensitivity muscle pain, tenderness, or
VLDL, plasma triglyceride levels; increases
to atorvastatin or its weakness, especially if
HDL concentration.
components, pregnancy, accompanied by fatigue or
(Kizior & Hodgson, 2021) unexplained persistent rise in fever.
Other drug forms: serum transaminase level.  Reinforce the benefits of
Tablets: 10 mg, 20 mg, 40 mg, therapy, and urge patient to
(Kizior & Hodgson, 2021)
80 mg comply if possible.
 Advise patient with
Pharmacokinetics diabetes to monitor blood
glucose levels closely.
Poorly absorbed from GI tract.
Protein binding: greater than 98%.
Metabolized in liver. Primarily excreted in
feces (biliary).
Half-life: 14 hrs

___Sheila K. Maceda, RN, MAN__ _______CLAIRE MAURICE G. JUANERO_____


Printed Name and Signature Printed Name and Signature
Clinical Instructor Student

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