Brain Tumor Detection via Machine Learning
Brain Tumor Detection via Machine Learning
Shahab Wahhab Kareem1,2, Bikhtiyar Friyad Abdulrahman1, Roojwan Sc. Hawezi1, Farah Sami
Khoshaba1, Shavan Askar1, Karwan Muhammed Muheden1, Ibrahim Shamal Abdulkhaleq1
1
Department of Information System Engineering, Erbil Technical Engineering College, Erbil Polytechnic University, Erbil, Iraq
2
Department of Information Technology, College of Engineering and Computer Science, Lebanese French University, Erbil, Iraq
Corresponding Author:
Shahab Wahab Kareem
Department of Information System Engineering, Erbil Technical Engineering College, Erbil Polytechnic
University
Kirkuk Road, 44001, Erbil, Kiurdistan, Iraq
Email: [Link]@[Link]
1. INTRODUCTION
In the age of e-healthcare and information technologies, physicians will deliver quality health care
to their patients [1]. This research discusses the problems relating to the segmentation and management of
dysfunctional usual tissues [2], [3], and brain tissues, such as grey matter (GM) processes, detection of white
matter (WM), and controlling of cerebrospinal fluid (CSF) from applicable magnetic resonance (MR)
imaging techniques and photos utilizing a support vector machine (SVM) classifier and applicable feature
extraction technique [4]. The tumor is defined as an unregulated and uncontrolled growth of cancer cells or
expansion grid [5]. Concept of brain tumor is considered an uncontrolled or unmaintained growth of cancer
or malignant cells. In simple forms, a brain tumor can be of two types, benign growth and forms of malignant
growth [6]. For patients, forms of benign brain tumors are structurally standardized including no active
(cancer) cells [6]. In patients, malignant brain tumors are structurally non-uniform (heterogeneous) including
forms of active cancer cells. Gliomas and meningioma are manifestations of forms of low-grade tumors and
growth known as benign tumors [7].
On the other hand, glioblastoma and astrocytoma are considered high-grade growth tumors
classified as malignant tumors [8]. According to World Health Organization (WHO) and, brain tumor
association of American Brain Tumor Speculation (ABTA), the most popular and accepted mode of
classification scheme utilizes grade I and grade IV scales to distinguish different forms of benign growth and
malignant tumor growth forms [9]. Benign cancers fell below stages of grade I (categorized) and grade II
glioma growth on this scale, and different forms of malignant tumors growth fall below grade categorization
of III growth and graded under IV glioma growth.
Grade I and II tumors tend to grow slowly, while grade II tumors tend to grow rapidly [10]. If a low-
grade brain tumor is not handled, it will progress to a high-grade brain tumor, which will then become a
malignant form of brain tumor showing irregular and uncontrolled growth. Patients with different forms of
grade II gliomas can be watched closely and have the magnetic resonance imaging (MRI) or computer
tomography (CT scans) every 6 to 12 months [11]. Every person, at any age, may be affected by a brain
tumor, and the effects on the body vary from person to person. Low-grade categorized as I and II glioma
(uncontrolled growth) benign tumors are considered to be curable following a complete surgical procedure in
this process, while grade III and IV forms of malignant brain tumors may be treated with different forms of
radiotherapy procedure, chemotherapy treatment, or a combination of the two treatment procedures [12].
Both type III and IV glioma, also known as anaplastic astrocytoma, are used in the term malignant
glioma. Anaplastic astrocytoma is a mid-grade tumor with irregular or uncommon growth features and a
higher growth index than most low-grade tumors [13]. Glioblastoma is also the most dangerous form and
type of astrocytoma seen among the patients, as well is categorized as the highest grade glioma in this
category. Glioblastoma is distinguished from other tumor types by the abnormal and uncontrolled forms of
accelerated growth of different types of blood vessels and the presence of uncontrolled types of necrosis
(dead cells) around the tumor segment in the patient [14]. Glioblastoma which is an extremely uncontrolled
form of growth, at the grade IV tumor stage, is a fast-growing and highly contagious, and malignant tumor
type as contrasted to other tumor groups via different types of medical imaging methods, segmentation is
used to detect infected tumor tissues [15]. Segmentation is a way of separating and differentiating a picture
into different blocks in terms of sharing common properties, such as color, shape, growth, structure, contrast,
brightness, development, border, and grey level in the patients [16]. It is a significant step in the processing
of pictures. The method of separating and differentiating different forms of tumor tissues such as oedema and
dead cells formation, from normal brain tissues and healthy tumors is categorized as different developmental
stages for WM, GM, and CSF using MR images or other imaging techniques is known as segmentation of
brain tumors [17].
tumors. MR imaging has two sequences, T1- and T2 weighted. T1-weighted MRI helps identify brain tumors
that have shifted to the cerebral spinal fluid spaces. The contrast used in T2-weighted MR imaging is used to
depict pathology on the other side is heavy. Brain tumors may be found nearby. Thus, the tumors are given
names based on which will classify them according to the types of cells. Tumors are usually found in the
brain and pituitary gland as the name indicates, glioma is a disease that affects the brain and the spinal cord.
Gliomas originate in the glial help cells of the brain. It's a tumor that occupies the brain, but is still able to
shape itself in the membrane of the dura, and arises from the membrane. One of the most often occurring
brain tumors in adults is of this kind is found to include between 15-20% of brain tumors [21]. Finally, a
pituitary tumor grows in the pituitary gland, which establishes hormonal equilibrium, which in turn regulates
the activity of other glands, which includes a portion of the menstrual cycle. T1-weighted MRI with three
differentiating the tumor groups using MRI to diagnose brain tumors leads to wasted time and misdiagnoses
[25]. Deep learning (DL) and image recognition algorithms are already used in recent computerized MR
diagnostic programs to cut both the time and the margin of error a deep learning-based, object recognition
technique utilizes multilayered neural networks and is part of the kind of machine learning called artificial
intelligence. It is possible for DL to learn from the same kind of data as machine learning algorithms do:
images, video, and text as well as when used by conventional techniques [24], but these are significantly
different approaches to solving the problem. In this research, we seek to build a web-based program that is
capable of using an in-depth T1 MRI scan for glioma, meningioma, and pituitary adnexa classifications
through DL so are suspected that health practitioners and scientists can now easily diagnose brain tumors
because of the free web-based tools created Often, this web-program can be used as a diagnostic tool for
brain tumor classifications (i.e., glioma, meningioma, pituitary). The experimental findings show that all
measured indicators can distinguish the various categories of brain tumors on the training dataset, which is
significantly higher than 98%. However, for all indicators the score is greater than or equal to 91%, except
for sensitivities and the major complication or comorbidity (MCC) for meningioma. On the preparation and
evaluation points, the convolutional neural network (CNN-based) model can accurately identify the various
brain tumor forms [26], [27]. An intriguing thesis on CNN is researching brain tumor classifications on
public MRI pictures, which used the technique of DL to a group over 3,400 different T1-weighted images of
the same subjects into 233 and 3,000 exclusive models. When run on two different datasets, the evolved
method produces overall accuracy of 96.13% and 98.7%.
2.3.2. Preprocessing
Preprocessing offers gain by refining some of the image functionality for eventual processing [24].
Until processing the MRI pictures, the following measures are applied: As seen in Figure 3(a), the red, green,
blue (RGB)-formed MRI image is first normalized into greyscale and then subjected to median filtering
Figure 3(b). Since more precise analysis is needed, the noise has been filtered out. Canny edge identification
Comparative evaluation for detection of brain tumor using … (Shahab Wahhab Kareem)
472 ISSN: 2252-8938
and detection method as depicted in Figure 3(c). To segment the picture, the edge detected image is needed.
The picture in Figure 3 is a procedure used to find the tumor's position in the brain's watershed segmentation
Figure 3(d). The segmentation of a picture is a series of segments. Segmentation seeks to reorganize picture
representation [24]. A marked picture in the product of watershed division in graphic, all the objects and
tools will have different values will be on the same scale, all the first object's pixels will have value 1, all the
second object's pixels' first, all other objects' pixels will have a second value [30], and so on This chart shows
in Figure 3 illustrates numerous preprocessing techniques applied to brain MR images.
Figure 3. Stages in preprocessing of MRI images (a) original image, (b) filtered image, (c) edge detected
image, and (d) segmented image
2.3.4. Classification
In certain cases, multi-layer perceptron (MLP) and a naive Bayes (NB) algorithm are used to
perform pattern recognition on photographs of the brain [36] to help them learn and make better decisions
This method involves creating an artificial neural network (ANN) [37] in which multiple layers map inputs to
a single output variable that feeds to a second one or multiple subsequent layers until a suitable response is
reached. Each neuron in the MLP is regulated by its special activation mechanism [29]. A feedback circuit is
known as a feedforward since it has no feedback [36]. It's all in the journal. When the goals for success and
actual results align, learning occurs by changing the association weights [38]. Because of this negative
feedback, [39] the system is known as derisively as 'backward pathogenesis'. As a goal, the total weight
values must be minimized such that each edge has a lower chance of error. Figure 4 show result of all the
mentioned stages, the result of the preprocessed image Figure 4(a), k-means segmented image result shown
in Figure 4(b), fuzzy c-means segmented image shown in Figure 4(c), clear border result in Figure 4(d), and
feature extracted image in Figure 4(e).
Figure 4. Classification for different MRI outputs, (a) original image, (b) k-means segmented image,
(c) fuzzy c-means segmented image, (d) clear border, and (e) feature extracted image
3. METHOD
3.1. Methods and eligibility criteria
A systematic review and comparative study have been conducted based on the acceptability and
relevance of the user data and speculation for the research process. Different methodological perspectives of
the research have been adopted effectively to analyze the findings. For allocating research and maintaining
the research process [40], research philosophy, research design, and ethical processes have been selected
aligning with the requirements of the research.
3.3. Ethics
Different ethical contexts have also been addressed in this research to assess the findings effectively.
Selection of the articles and journals have been conducted based on the reliability and acceptability of the
published articles. To assess the ethical contexts, different criteria for the research processes have been
addressed effectively.
4.2. Discussion
Cancer that has developed in the brain is called a brain tumor [31]. Benign and malignant tumors
may be located in the brain. Clustering is commonly used in the diagnosis of diseased tissues. It is recognized
that low-grade I and high-grade gliomas are considered to be curable [32]. Tumors with grade III and IV
properties are usually are well-tolerated by radiotherapy and chemotherapy [33]. Glioblastoma is the most
dangerous and the most category form of astrocytoma [35]. Grade IV glioma is a very malignant tumor with
Comparative evaluation for detection of brain tumor using … (Shahab Wahhab Kareem)
474 ISSN: 2252-8938
a high incidence of grade V metastasis. the procedure of differentiating the tumor from normal brain tissue,
for example.
Imaging or pictorial analysis is central to the modern body of knowledge. It's very hard to get your
hands around the procedure of making some kind of graphic presentation. Unless otherwise stated,
visualizations of the feature are referred to as medical imaging in this section. Algorithms can resolve
complicated medical imaging issues to some degree. An embedded co-processor uses a converter that
converts an algebra to a hard-wired arithmetic algorithm. Because the geometry of an application's artifacts is
quite good, very effective, it would likely be very inefficient through the use of computer graphic modeling.
Since conformal geometry does have a defined geometry at a coordinate-free stage, it might be able to meet
these problems to a significant degree. Potential is greater than the number. a procedure that is effective and
precise in terms of both detection and measurement of three- and registration of 3D shapes you don't have to
be overly complicated with free curves and free surfaces. The iterative closest point (ICP) approach will
accommodate the most freedom and is built on iterative calculations. There are around a million sums or
contractions in the framework profile. A 4-dimensional (4D) image of elements or 4 sets of 4 elements
conformal geometric algebra is used for the initial detection of the tumor when running on a general-purpose
processor. Neural networks can be used to detect some anatomical features of the tumor this is effective when
applied to colored photographs as well. The processing time required for this algorithm can be very short, as
long as it is there are few photographs. Even, as well as the tumor volume, we detected with the aid of the
form and diameter of the detected tumor using the methodology is more efficient, but it cannot overcome
high computational costs.
5. CONCLUSION
MRI image techniques used to determine different forms of benign and malignant growths have
been an important aspect of the treatment procedures of the patients. In this way, medical professionals can
determine the required level of strategic aspects to understand the processes and aspects needed for the
treatment processes. To analyze the research outcomes, different aspects of the MRI imaging techniques have
been discussed in this report. A brief comparative analysis of the literature has been also conducted to review
the findings. The conceptual models use several levels of abstraction to deal with the data in DL algorithms
in medical imaging, medical processing, research, and bioinformatics, DL has exploded As several other
fields of healthcare have discovered, DL and neural networks have shifted the balance of diagnosis and
inference, these advances have had widespread effects on various forms of pathology, such as liver,
esophageal, brain tumor, and retinal disease, too As major objectives of this article is to examine the popular
applications of DL as it relates to brain tumor research (e.g., segmentation, classification, prediction,
evaluation). This book (i.e., DL in brain tumor analysis) contains several research contributions to the area.
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BIOGRAPHIES OF AUTHORS
Dr. Shahab Wahhab Kareem Shahab Wahhab Kareem his BSc in Control and
Computer Engineering from the University of Technology Baghdad in 2001, an MSc in
Software Engineering from Salahadeen University in 2009, and a Ph.D. in Yasar University
Izmir, Turkey in 2020. My research interests include machine learning and big data. I’m a
lecturer at the Information System Eng. (ISE) Department (2011-till now). He can be contacted
at email: [Link]@[Link] or shahabwk@[Link].
Dr. Roojwan Scddeek Hawezi I got a BSc degree from Baghdad University in
Physical science, then I got a higher Diploma in Computer science. Back in 2003, I got my
MSc degree then finally the Ph.D. in 2007 in Computer science from Baghdad too. I'm a
specialist in digital image processing. I'm the former head of the Information System Eng. (ISE)
Department. She can be contacted at email: [Link]@[Link].
Farah Sami Khoshaba She got the [Link]. degree from University of
Technology/Baghdad in the science of Computer and Control engineering in 1999, and worked
as an engineer at the same department, as she was in charge of control laboratory and process
laboratory. Then in 2006, she got the [Link]. degree at the same Department in the
Specialization of Mechatronics. She's a member of academic staff with a grade of lecturer at the
Information System Engineering (ISE) Department (2011-till now). She can be contacted at
email: [Link]@[Link].
Comparative evaluation for detection of brain tumor using … (Shahab Wahhab Kareem)