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VUJ Obstruction in Newborns

The document discusses VesicoUreteric Junction (VUJ) Obstruction, which refers to a restriction in urine flow where the ureter meets the bladder. It most commonly involves a narrowed, stiff section of ureter. It affects about 1 in 1500-2000 newborns and can present without other abnormalities. Ultrasound, MCU, and nuclear medicine scans are used for testing. Many cases resolve on their own, while others may require temporary stents, surgery, or diversion of the ureter. Outcomes vary, with half of children improving on their own and about 10-20% requiring surgery. Regular follow-up with ultrasounds and scans monitors the condition.

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Muhammad Farhan
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0% found this document useful (0 votes)
105 views2 pages

VUJ Obstruction in Newborns

The document discusses VesicoUreteric Junction (VUJ) Obstruction, which refers to a restriction in urine flow where the ureter meets the bladder. It most commonly involves a narrowed, stiff section of ureter. It affects about 1 in 1500-2000 newborns and can present without other abnormalities. Ultrasound, MCU, and nuclear medicine scans are used for testing. Many cases resolve on their own, while others may require temporary stents, surgery, or diversion of the ureter. Outcomes vary, with half of children improving on their own and about 10-20% requiring surgery. Regular follow-up with ultrasounds and scans monitors the condition.

Uploaded by

Muhammad Farhan
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as PDF, TXT or read online on Scribd

VesicoUreteric Junction (VUJ)

Obstruction
What  is  it?   What  tests  are  performed?  
Vesicoureteric   junction   obstruction   (VUJO)   refers   Ultrasound  
to   a   restriction   to   urine   flow,   where   the   ureter  
This   is   the   same   type   of   scan   used   during  
(drainage   tube   from   the   kidney)   meets   the  
pregnancy.  It  is  able  to  demonstrate  the  dilatation  
bladder.  
of   the   urinary   system,   identifying   the   ureters  
throughout   their   length,   and   to   measure   the  
What  causes  it?   degree   of   dilatation.   The   ultrasound   is   able   to  
assess  the  state  of  the  kidney  and  bladder  as  well.  
Most   commonly,   there   is   a   narrowed   and   stiff  
section   of   ureter,   just   as   it   enters   the   bladder.   Micturating  cystourethrogram  (MCU)  
Sometimes,   there   are   too   many   circular   (round)   This   test   helps   to   determine   whether   the  
muscle   fibres   in   this   section   that   squeeze   the   dilatation  of  the  ureter  is  due  to  reflux  (backflow)  
bottom   end   of   the   ureter   and   stop   it   draining   of   urine   from   the   bladder,   rather   than   obstruction  
properly.   (see  MCU  sheet  for  more  information)  

Nuclear  medicine  
Who  gets  it?   Renal   scans   help   to   determine   the   relative  
VUJ  obstruction  is  identified  in  about  1  per  1500-­‐ function   of   the   two   kidneys,   and   may   provide  
2000   newborns.     It   usually   occurs   without   other   information  about  drainage.  These  studies  should  
abnormalities.   be  performed  in  a  paediatric  centre  to  obtain  the  
best   results.   A   small   amount   of   radioactive  
material   is   injected   into   the   child’s   bloodstream  
How  does  it  present?   and   a   special   camera   takes   pictures   of   the  
kidneys,   recording   the   material   passing   through  
When   there   is   a   blockage   or   impairment   of   urine  
and  draining  from  the  kidneys.    
flow,  the  urine  builds  up  behind  the  blockage.  This  
means  that  the  upper  part  of  the  ureter  becomes  
distended,  all  the  way  up  to  the  collecting  system   What  are  the  treatment  options?  
of   the   kidney.   This   is   commonly   picked   up   on   an  
ultrasound   scan   performed   during   pregnancy   (See   Many   VUJ   obstructions   are   diagnosed   before  
antenatal  hydronephrosis  information  sheet).   birth,   so   most   of   these   children   are   healthy   and  
have   no   symptoms.   Many   of   them   will  
If   dilatation   has   not   been   identified   before   birth,  
spontaneously   correct   with   time,   so   factors   such  
VUJ  obstruction  may  present  with:  
as   kidney   function   and   degree   of   dilatation  
- urinary  tract  infection   influence  whether  any  treatment  is  required.  
- abdominal  or  flank  pain  
Indications  for  intervention  
- abdominal  mass  or  swelling  
- urinary  tract  infections  
- urolithiasis  (stones  in  the  urinary  tract)  
- incidentally   (found   on   ultrasound   performed   - increasing  dilatation  
for  another  reason)   - reduction  in  function  of  the  associated  kidney  

This  information  sheet  is  for  educational  purposes  only.    


Please  consult  with  your  doctor  or  other  health  professional  to  make  sure  this  information  is  valid  for  your  child  
VesicoUreteric Junction (VUJ)
Obstruction
Intervention  options  
Placement   of   temporary   stent   across   the  
obstruction  can  protect  the  kidney  function  while  
the   baby   is   growing   to   “buy   time”   while   natural  
improvement  has  a  chance  to  occur.  

In   some   cases   surgical   treatment   may   be  


necessary,  excising  the  blocked  part  of  the  ureter  
and  reimplanting  the  good  ureter  into  the  bladder  
(see  ureteric  reimplantation  sheet).  
In   some   severe   cases,   ‘diversion’   is   necessary   in  
the   short   term,   making   a   ‘stoma’   or   direct  
connection   between   the   blocked   ureter   and   skin  
to  allow  complete  decompression  of  the  affected  
system.     a   ureteric   reimplantation   would   then   be  
undertaken   some   time   later,   when   the   child   and  
bladder  are  bigger,  and  the  ureter  less  distended.  

What  are  the  outcomes?  


In   up   to   a   half   of   children   with   VUJ   obstruction,  
the  dilatation  improves  by  itself.  
In   just   over   a   third   of   patients,   the   dilatation   will  
stay  the  same  without  deteriorating.    

In   10-­‐20%   of   children,   surgery   is   performed   for  


deteriorating   kidney   function,   or   persistent  
urinary  tract  infections.  

What  is  the  follow-­‐up?  


The   doctors   will   review   your   child   regularly   with  
repeated  ultrasound  scans.    
Nuclear  medicine  studies  to  monitor  function  may  
be  arranged  by  your  paediatric  urologist.      

This  information  sheet  is  for  educational  purposes  only.    


Please  consult  with  your  doctor  or  other  health  professional  to  make  sure  this  information  is  valid  for  your  child  

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