THYROID MCQ DR NAGEEB
1) Regarding thyroid hormone , which is true ?
a) Most of T4 converted into T3 in cytoplasm of the cell
b) thyroid hormone has a nuclear receptor
c) thyroid hormone has a cytoplasmic receptor
d) Most of T3 converted into T4 in cytoplasm of the cell
e) A & b are correct
2) Regarding thyroid hormone , which is true ?
a) Alpha receptor responsible for general metabolic function
b) Beta receptor responsible for feedback regulation of hormone
c) all of the above
3) Regarding thyroid hormone , which is true ?
a) Calorigenic hormone increase in basal metabolic rate
b) Increases blood glucose level by stimulating glycogenolysis & gluconeogenesis
c) decrease blood cholesterol level
d) all of the above
4) Regarding thyroid hormone , which is true ?
a) Increase sensitivity of SAN to the catecholamines by increasing the number of B-receptors.
b) -decrease peripheral resistance: due to peripheral VD
c) Lead to decreasing or unaltered diastolic ABP.
d) All of the above
5) Regarding thyroid hormone , which is true ?
a) Cause diuresis & increase excretion of K+ , Ca++ ,Po–in urine
b) necessary for maintenance of milk production
c) Stimulation of growth hormone secreting cells in the anterior pituitary
d) All of the above
6) Regarding thyroid hormone , which is true ?
a) increase in T3 & T4 levels suppresses release of TSH is direct –ve feedback
b) increase in T3 & T4 levels suppresses release of TRH from the hypothalamus is indirect –
ve feedback
c) -Long Acting Thyroid Stimulator has long duration effect compared to TSH
d) All of the above
MAKE IT EASY 1
THYROID MCQ DR NAGEEB
7) A patient with Hypothyroidism , Regarding thyroid hormone , which is true ?
a) Excess iodine stored in gland with no increase in thyroxine level
b) Excess iodine cause the gland returns to normal condition and decreases the hyperplasia
c) Wolff-Chaikoff effect
d) All of the above
8) Hypothyroidism doesn’t cause
a) cretinism
b) myxoedema
c) early genital development
d) hair loss
9) An adult male suffers from deficiency of thyroid hormone, he has:
A. mental Apathy.
B. Anaemia.
C. Constipation.
D. All of the above.
10) Which of the following is inconsistent with the diagnosis of Graves’ disease?
a) Increased heart rate
b) Increased plasma levels of (T3)
c) decrease plasma levels of (TSH)
d) all of the above
11) A patient with hypothyroidism is likely to have :
a) subnormal body temperature
b) decreased heart rate
c) high TSH Level
d) all of the above
12) Thyroid hormones, all are correct , Except:
a) They are essential for normal fertility
b) Iodine is essential for thyroid hormone synthesis.
c) Are synthesized from steroid
d) T3 is more potent than T4.
MAKE IT EASY 2
THYROID MCQ DR NAGEEB
13) Which of the following findings is most likely in a patient who has hypothyrodism?
A) Palpitations
B) Increase cholesterol level
C) Increased respiratory rate
D) Increased cardiac output
14) Hypersecretion of Thyroxin would be caused by an increase in the release of:
A) FSH or LH
B) GH
C) TSH or ACTH
D) TRH or TSH
15) Which of the following would be expected with normal thyroid function?
a. TSH secretion is regulated primarily by the pituitary level of T3.
b. T4 is the physiologically active hormone.
c. Thyroid-stimulating hormone (TSH) is secreted from the posterior pituitary.
d. TSH initiates thyroid hormone secretion via activation of nuclear receptors in thyroid
gland cells.
16) A 46-year-old woman on lithium therapy for her bipolar disorder presents with
complaints of weakness, arthralgia, and constipation. Blood work reveals
hypercholesterolemia, increased levels of TSH, and decreased free T4 levels. Which of
the following is also likely to be associated with her hypothyroid state?
a. Heat intolerance
b. Increased metabolic rate
c. Sleepiness
d. Tachycardia
17) A 29-year-old man complains of weight gain, decreased energy, dry skin, and brittle hair
for the past 6 months. He was diagnosed with hypothyroidism and started on thyroid
hormone treatement . A decrease in which of the following laboratory values would be
expected as result of starting treatment?
a. Free T4
b. T3
c. Plasma cholesterol
d. Vitamin A
MAKE IT EASY 3
THYROID MCQ DR NAGEEB
18) Which of the following statements regarding the thyroid gland are correct?
a) A person with hypothyroidism has a low plasma TSH concentration.
b) Calcitonin is secreted by the follicular cells of the thyroid gland.
c) A person with hypothyroidism has a high plasma TSH concentration.
d) Calcitonin stimulates the activity of osteoclasts.
19) A patient has a goiter associated with high plasma levels of both TRH and TSH. Her
heart rate is elevated. This patient most likely has which condition?
A) An endemic goiter
B) A hypothalamic tumor secreting large amounts of TRH
C) A pituitary tumor secreting large amounts of TSH
D) Graves’ disease
20) Regarding thyroid hormone , which is true ?
a- Patient with primary hyperthyroidism show High T3-T4 and Low TSH
b- Patient with primary hypothyroidism show Low T3-T4 and High TSH
c- Patient with primary hyperthyroidism show High T3-T4 and High TSH
d- Patient with primary hypothyroidism show High T3-T4 and Low TSH
e- A & b are correct
21) A patient has an elevated plasma thyroxine (T4) concentration, a low plasma TSH
concentration, and her thyroid gland is smaller than normal. What is the most likely
explanation for these findings?
A) A lesion in the anterior pituitary that prevents TSH secretion
B) The patient is taking anti thyroid drugs
C) The patient is taking thyroid extract treatment
D) Graves’ disease
MAKE IT EASY 4
Thyroid MCQ Dr Nageeb
1) Regarding thyroid hormone , which is true ?
a) Most of T4 converted into T3 in cytoplasm of the cell
b) thyroid hormone has a nuclear receptor
c) thyroid hormone has a cytoplasmic receptor
d) Most of T3 converted into T4 in cytoplasm of the cell
e) A & b are correct
2) Regarding thyroid hormone , which is true ?
a) Alpha receptor responsible for general metabolic function
b) Beta receptor responsible for feedback regulation of hormone
c) all of the above
3) Regarding thyroid hormone , which is true ?
a) Calorigenic hormone increase in basal metabolic rate
b) Increases blood glucose level by stimulating glycogenolysis & gluconeogenesis
c) decrease blood cholesterol level
d) all of the above
4) Regarding thyroid hormone , which is true ?
a) Increase sensitivity of SAN to the catecholamines by increasing the number of B-receptors.
b) -decrease peripheral resistance: due to peripheral VD
c) Lead to decreasing or unaltered diastolic ABP.
d) All of the above
5) Regarding thyroid hormone , which is true ?
a) Cause diuresis & increase excretion of K+ , Ca++ ,Po–in urine
b) necessary for maintenance of milk production
c) Stimulation of growth hormone secreting cells in the anterior pituitary
d) All of the above
6) Regarding thyroid hormone , which is true ?
a) increase in T3 & T4 levels suppresses release of TSH is direct –ve feedback
b) increase in T3 & T4 levels suppresses release of TRH from the hypothalamus is indirect –
ve feedback
c) -Long Acting Thyroid Stimulator has long duration effect compared to TSH
d) All of the above
Make it Easy 1
Thyroid MCQ Dr Nageeb
7) A patient with Hypothyroidism , Regarding thyroid hormone , which is true ?
a) Excess iodine stored in gland with no increase in thyroxine level
b) Excess iodine cause the gland returns to normal condition and decreases the hyperplasia
c) Wolff-Chaikoff effect
d) All of the above
8) Hypothyroidism doesn’t cause
a) cretinism
b) myxoedema
c) early genital development
d) hair loss
9) An adult male suffers from deficiency of thyroid hormone, he has:
A. mental Apathy.
B. Anaemia.
C. Constipation.
D. All of the above.
10) Which of the following is inconsistent with the diagnosis of Graves’ disease?
a) Increased heart rate
b) Increased plasma levels of (T3)
c) decrease plasma levels of (TSH)
d) all of the above
11) A patient with hypothyroidism is likely to have :
a) subnormal body temperature
b) decreased heart rate
c) high TSH Level
d) all of the above
12) Thyroid hormones, all are correct , Except:
a) They are essential for normal fertility
b) Iodine is essential for thyroid hormone synthesis.
c) Are synthesized from steroid
d) T3 is more potent than T4.
Make it Easy 2
Thyroid MCQ Dr Nageeb
13) Which of the following findings is most likely in a patient who has hypothyrodism?
A) Palpitations
B) Increase cholesterol level
C) Increased respiratory rate
D) Increased cardiac output
14) Hypersecretion of Thyroxin would be caused by an increase in the release of:
A) FSH or LH
B) GH
C) TSH or ACTH
D) TRH or TSH
15)Which of the following would be expected with normal thyroid function?
a. TSH secretion is regulated primarily by the pituitary level of T3.
b. T4 is the physiologically active hormone.
c. Thyroid-stimulating hormone (TSH) is secreted from the posterior pituitary.
d. TSH initiates thyroid hormone secretion via activation of nuclear receptors in thyroid
gland cells.
16)A 46-year-old woman on lithium therapy for her bipolar disorder presents with
complaints of weakness, arthralgia, and constipation. Blood work reveals
hypercholesterolemia, increased levels of TSH, and decreased free T4 levels. Which of
the following is also likely to be associated with her hypothyroid state?
a. Heat intolerance
b. Increased metabolic rate
c. Sleepiness
d. Tachycardia
17) A 29-year-old man complains of weight gain, decreased energy, dry skin, and brittle hair
for the past 6 months. He was diagnosed with hypothyroidism and started on thyroid
hormone treatement . A decrease in which of the following laboratory values would be
expected as result of starting treatment?
a. Free T4
b. T3
c. Plasma cholesterol
d. Vitamin A
Make it Easy 3
Thyroid MCQ Dr Nageeb
18) Which of the following statements regarding the thyroid gland are correct?
a) A person with hypothyroidism has a low plasma TSH concentration.
b) Calcitonin is secreted by the follicular cells of the thyroid gland.
c) A person with hypothyroidism has a high plasma TSH concentration.
d) Calcitonin stimulates the activity of osteoclasts.
19)A patient has a goiter associated with high plasma levels of both TRH and TSH. Her
heart rate is elevated. This patient most likely has which condition?
A) An endemic goiter
B) A hypothalamic tumor secreting large amounts of TRH
C) A pituitary tumor secreting large amounts of TSH
D) Graves’ disease
20) Regarding thyroid hormone , which is true ?
a- Patient with primary hyperthyroidism show High T3-T4 and Low TSH
b- Patient with primary hypothyroidism show Low T3-T4 and High TSH
c- Patient with primary hyperthyroidism show High T3-T4 and High TSH
d- Patient with primary hypothyroidism show High T3-T4 and Low TSH
e- A & b are correct
21) A patient has an elevated plasma thyroxine (T4) concentration, a low plasma TSH
concentration, and her thyroid gland is smaller than normal. What is the most likely
explanation for these findings?
A) A lesion in the anterior pituitary that prevents TSH secretion
B) The patient is taking anti thyroid drugs
C) The patient is taking thyroid extract treatment
D) Graves’ disease
Make it Easy 4
