Male Genital Tract Pathology-3
[Link], M.D.
Epididymitis
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Granulomatous epididymitis
Penis
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Congenital anomalies
• Hypospadias
• Epispadias
• Phimosis
• Paraphymosis
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Hypospadias
Epispadias
• Malformations of urethral groove and urethral canal
may create an abnormal opening.
--ventral surface (hypospadias)
--dorsal surface (epispadias)
It may be associated with abnormalities in
--descent of testes
--malformation of urinary tract
Complications: infections of urinary tract
infertility
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The catheter seen here is in a groove on the undersurface below the tip of the penis and
enters the urethra. This abnormal opening is known as a hypospadias. Such an anomaly
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is not common but can lead to problems with urination and ejaculation.
The groove on the dorsal aspect of the penis extending from the urethral meatus is an abnormality
termed epispadias. This is an uncommon anomaly of varying degrees of severity. When severe, it
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can lead to problems with urination and ejaculation.
Infalmmations
Balanoposthitis
Specific infections: syphilis, gonorrhea, chancroid,
Granuloma inguinale, Herpes.
Non-specific infections: Candida albicnas, Gardnerella,
pyogenic bacteria
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The glans penis surrounding the penile urethral meatus demonstrates erythema and
exudate, typical for a balanitis. The retracted foreskin is also acutely inflamed, a
condition called posthitis. Together, this inflammatory condition is known as
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balanoposthitis.
Syphilitic chancreCSBRP-July-2012
occurring on the glans penis
Condyloma accuminatum
•HPV 6 & 11
•Sexually transmitted
•Most lesions occur in the coronal sulcus
•Single / multiple sessile or pedunculated red papillary
excrescences
•Histologically acanthosis, hyperkeratosis, koilocytosis
•They tend to recurr
•No malignant potential
•Giant condylomas are known as Buschke-Lowenstein
tumor CSBRP-July-2012
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Large confluent 1 cm to 8 cm hyperpigmented warty
nodules. CSBRP-July-2012
Large confluent 1 cm to 8 cm hyperpigmented warty
nodules
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Bowen’s disease
•>35yrs
•Shaft of the penis and scrotum
•Solitary, thickened, gray white, opaque plaque with shallow
ulceration and crusting
•On the glans it produces velvety lesion
•Histologically: acanthosis, mitoses, dysplasia and other nuclear
features of malignancy
•Dermo-epidermal margin is well demarcated.
•Develops in to carcinoma
•Bowenoid papulosis: younger age, HPV-16, resembles condyloma,
No malignant potential
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Bowenoid papulosis - Scrotum
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Squamous cell carcinoma – Penis
•Correlation exists between circumcision and occurance of
Ca
•HPV 16 & 18
•Bowen’s disease
•Others: smoking
•Age: 40-70yrs
•Morphology: glans and inner surface of prepuce near
coronal sulcus, Papillary / flat
•Verrucous carcinoma: WD scc, low malignant potential,
locally invasive, rarely metastsizing
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Here is a squamous cell carcinoma of the head of an uncircumcised
penis. The neoplasm is reddish-tan with an ulcerated surface
This is a squamous cell carcinoma of the penis (penectomy specimen)
that is a larger, reddish brown fungating mass
Papillomatous growth
pattern
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Papillomatous growth
pattern
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Penile squamous cell carcinoma involving the glans in a vegetant fashion
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Verrucous carcinoma
Bulbous expansions of verrucous carcinoma
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Why these people are more prone
for carcinoma of penis ?
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E N D
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Contact:
[Link], M.D.,
Associate Professor of Pathology,
Sri Devaraj Urs Medical College,
Kolar-563101,
Karnataka,
INDIA.
CSBRPRASAD@[Link]
