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Model Paper Set-B Medicinal Chemistry-I Bp402T: Section A MM 75 1. Attempt All Questions in Brief. 10 X 1 20

This document contains a model paper for the subject Medicinal Chemistry-I with three sections: Section A contains 20 short answer questions testing knowledge of drug metabolism, receptor types, drug classes and other core concepts. Section B requires explaining the mechanism of action and structure-activity relationships of select drug classes with examples. Section C involves longer explanations of drug metabolism principles, structure-activity relationships of various drug classes, and details on specific drugs including their structure, mechanism of action and uses. The paper tests understanding of fundamental medicinal chemistry concepts and ability to communicate knowledge in writing.

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249 views1 page

Model Paper Set-B Medicinal Chemistry-I Bp402T: Section A MM 75 1. Attempt All Questions in Brief. 10 X 1 20

This document contains a model paper for the subject Medicinal Chemistry-I with three sections: Section A contains 20 short answer questions testing knowledge of drug metabolism, receptor types, drug classes and other core concepts. Section B requires explaining the mechanism of action and structure-activity relationships of select drug classes with examples. Section C involves longer explanations of drug metabolism principles, structure-activity relationships of various drug classes, and details on specific drugs including their structure, mechanism of action and uses. The paper tests understanding of fundamental medicinal chemistry concepts and ability to communicate knowledge in writing.

Uploaded by

SwarnA Tamta
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as PDF, TXT or read online on Scribd

MODEL PAPER SET-B

MEDICINAL CHEMISTRY-I BP402T

SECTION A
MM 75
1. Attempt all questions in brief. 10 x 1 = 20

[Link] 1 reaction of drug metabolism are also called as


[Link] biotransformation means
3. Drugs which have same physical or chemical properties and produce similar biological action are
called
4. Which of the following is precursor of adrenaline biosynthesis
5. MAO stands for
6. COMT stands for.
7. Adrenaline is less potent than phenylephrine.
8. Sympathomimetic drug which produces biological action by interaction with receptor are called
9. Salbutamol is used for symptomatic relief of.
10. Which functional group is present in catechol ring
11. Beta 2 receptor are predominantly found in which system
[Link] of the following is both alpha and beta blockers
[Link] of the following is a cholinergic neurotransmitter
14. Which of the following is a cholinesterase reactivator
15. Neuroleptic drug are also known as
16. Grand mall seizures are also known as
17. Chemical name of phenytoin is
18. Which of the following is a dissociative anaesthesia
19. Define general anaesthesia
20. Draw structure of morphine.

SECTION B

2. Attempt any two parts of the following: 2 x 10 = 20

1. Explain MOA of anticonvulsant and discuss SAR of hydantoin with examples


2. Write synthesis of phenylephrine, salbutamol, tolazoline and propranolol
3. Write synthesis, MOA and uses of diazepam and phenytoin

SECTION C

3. Attempt any five parts of the following: 7 x 5 = 35

1. Explain drug metabolism principles with examples


2. Explain the effect of ionization, solubility and partition coefficient in relation to biological action of
drug
3. Write details note on adrenergic receptor and their derivatives.
4. Explain SAR of BDZ and Barbiturates with examples..
5. Explain SAR of phenothiazines.
6. Give Structure, MOA and uses of atropine sulphate and dicylomine hydrochloride
7. Write a short note on sedative and hypnotic.
8. Explain SAR of morphine analogues..
9. Write structure, MOA and uses of aspirin and acetaminophen.

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