Communicable Diseases Course Overview
Communicable Diseases Course Overview
CHAIN OF INFECTION
- Leavell & Clark
- There is always interaction between this
components
AGENTS
o Self limiting a. COVID-19
o Long-term b. MERS
Viruses
immunity c. SARS-Cov
(vaccines)
o Needs of a. Pneumonia
Bacteria
medication b. Tuberculosis
oMicroscopic, 4 groups:
one-celled 1. Sarcodina - 1. Infectious agent
organisms that ameba - Eradicate before transmission
can be free-living 2. Mastigophora - - Use disinfectant or appropriate
Protozoa or parasitic in flagellates chemicals
nature 3. Ciliophora -
oMOT : fecal oral ciliates 2. Reservoir
route 4. Sporozoa - - Environment of the agent
Balantidium
Fungi oReproduce by 3 major groups: 3. Portal of exit
means of spores 1. Mold – - Anything that comes outside the body
oOmnipresent Aspergillosis - Bodily fluid, waste, or byproducts
(land, decaying (dead leaves,
matter, soil, stored grain, 4. Mode of transmission
moist areas) composites piles, - Weakest link
SNAB
COMMUNICABLE DISEASES
DISEASE CONTROL
TRANSMISSION BASED PRECAUTION
1. Airborne – transmitted through air
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COMMUNICABLE DISEASES
QUARANTINE
- Limitation of the freedom of movement
- Target: Well person
- Basis: longest incubation period
STEPS:
1 Renin release
2 Angiotensinogen into Angiotensin I
3 Angiotensin I into Angiotensin II
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COMMUNICABLE DISEASES
2. Vital load
1. CONFIRMATORY o High level= increased disease severity and
- ensure prompt diagnosis using molecular transmissibility
(NAAT/RTPCR)
3. Viral shedding
Diagnosis: o expulsion and release of viral materials
1. Reverse transcriptase polymerase chain following successful reproduction in the
reaction (RT-PCR) – host
o Gold standard for diagnosis COVID-19 o Severe covid = longer viral shedding
Nucleic acid implication test (NAAT)
or molecular testing - Detects the 3. RESPOND
antigen - treatment selection is determined by
2. Rapid Antigen test severity of disease and risk factors
o Best for case finding, contact tracing,
outbreak investigation A. Non severe (mild and moderate) without
o Diagnostic and confirmatory tests for risk factor (covid-19):
close contact, and COVID-19 suspect and o Symptom management and supportive
probable cases care
o Monitoring
2. ASSESS
- provide early clinical assessment and B. Non severe with risk factors:
evaluation to determine if the patient has MEDICATION DESCRIPTION ROUTE
risk factors, emergency signs, or symptoms o Indication: Used
that require treatment, clinical referral or to treat mild to
admission to hospital care; Categorize moderate
severity o Prevent the
growth of the
A. Most common symptoms: virus
- Fever Nimatrelvir o WOF: non-stop
- Loss of tase or smell Oral
& Ritonavir nausea and
- Dry cough
vomiting,
- Tiredness
anorexia,
abdominal pain,
B. Less common:
jaundice, dark
- Body aches
urine, clay
- Sore throat
colored stool
- Diarrhea
o Indication: Mild
- Conjunctivitis
to moderate
- Headache
o Not for pregnant,
- Rash on skin or discoloration
breastfeeding
women, and
C. Serious symptoms:
children due to
- DOB Molnupiravir Oral
lack of evidence
- Chest pain or pressure
o Most used in the
- Loss of speech or movement
Philippines
o WOF: Diarrhea
D. Incubation period
- 5-6 days average; 14 days longest and Allergic
reaction
E. Additional confirmatory tests (COVID-19): Remdesivir o Inhibits viral SQ
1. X-ray: ground glass opacities replication by injection
terminating RNA
transcription
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COMMUNICABLE DISEASES
prematurely PREVENTION
o Target: Omicron - Hand hygiene
o WOF: back pain, o Alcohol
chest tightness, o Antimicrobial soap
dark colored - Mask
urine, flushing, - Physical distancing
headache, - Avoid 3Cs
hives/itching, - Avoid touching surfaces in public setting
light colored - Regular cleaning/disinfection
stools, o 0.5% chlorine
hyperemesis o Bleach 1:10
headache,
hives/itching, HEALTH EDUCATION
light A. Covid and disinfection: not recommended
o Outdoor disinfection
o Spraying of individual with
C. Severe or critical: disinfectant (tunnel, cabinet, or
o Symptomatic and supportive care chamber)
o O2 therapy o Disinfecting food packages
o Corticosteroids (oral or IV)
- serve as immunosuppressant and anti- B. Covid and masks
inflammatory o Prolonged use of masks does not
o Venous thromboembolism (VTE) cause CO2 intoxication nor oxygen
prophylaxis deficiency
- prevent deep vein thrombosis o Do not wear masks when
o Immunomodulator performing vigorous PA
- modifies, or modulates, the immune
system to help your body respond to a COVID 19 AND MASKING
disease or illness A. Non-medical fabric masks for general public
- Interleukin-6 receptor blocker o Wash in soap/detergent and hot
(tocilizumab or sarilumab) water at least OD or wash it room
- Janus kinases - JNK inhibitor (Baricitnib) temperature water, followed by
o Hospitalized pediatric age 2 to less boiling (for reusable mask)
than 18 years of age that requires B. Medical masks for high-risk groups
oxygen, mechanical ventilation or C. Respirators for medical front liners
ECMO
COVID-19: PREGNANCY/BREASTFEEDING
NURSING CARE - Pregnant women at higher risk for severe
- Symptomatic and supportive illness/complication
1. Fluid intake - No evidence to suggest increased risk of
2. DBCT abortion;
3. Management of fever - No evidence of impaired fetal
4. Positioning development,
- reposition in different position - No evidence of intrauterine infection from
o redistributes blood and air flow vertical transmission
more evenly and improving gas - Maintain skin to skin contact after delivery
exchange - Continue breastfeeding
o prone to prevent atelectasis in o Hand hygiene and face mask
order to re-expand the lungs o Express breastmilk
o Wet nursing or donor human milk
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COMMUNICABLE DISEASES
C. Rescheduling
o Currently diagnosed or with
symptoms of COVID-19
o History of exposure to confirmed
or suspected COVID-19 case in the
past 14 days
o Received convalescent plasma or
monoclonal antibodies for COVID-
19 in the past 90 days
1. Natural – you have it within you o Women in the first 3 months of
2. Acquired – occurs after a person receives pregnancy
antibodies from another source
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COMMUNICABLE DISEASES
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2. Others:
o Anemia
o Jaundice
o DENV > continuous capillary injury
D. COMPLICATION (plasma leakage) > platelet activation
o Cerebral Hypoxia – 4-6 minutes (consumption) > bleeding
brain sustain oxygen
o Liver failure E. DIAGNOSTIC TEST
o Kidney failure 1. Dengue N1
2. Dengue blot test
E. DIAGNOSIS 3. Platelet count Hct (increases)
a. History o F: 35-47%
b. Peripheral blood smear – similar to o M: 42-52%
CBG 4. Rumpel Leede test (tourniquet test)
F. TREATMENT F. MANIFESTATION
a. Anti-malaria-lumefantrine 1. Fever 3 days or more
b. Chloroquine o Grades:
c. Primaquine Dengue fever
G1
symptoms
G. PREVENTION G2 G1 + bleeding
o Chemically treated mosquito nets G3 G2 + circulatory
o Larvae eating fishes - streaming failure
*Check for
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COMMUNICABLE DISEASES
I. DIARRHEAL DISEASE
1. MOT
- fecal oral route
H. PREVENTION - 5Fs:
o Food
o Fingers
o Feces
o Fomites
o Flies
2. TYPES
1. Acute watery
- Lasts several hours or days, and
includes cholera
a. Search and destroy
b. Seek Early consultation – 3 days fever
2. Acute bloody
c. Secure self-protection measures – mosquito
- Dysentery
repellant, pants, long sleeves
d. Support Fogging/spraying in hotspot areas
3. Persistent diarrhea
e. Aceite – efficacent oil
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COMMUNICABLE DISEASES
A. MANIFESTATION
II. CHOLERA - pus in the stool
- Vibrio cholerae - Men are asymptomatic and passes it on
- Severe diarrhea and dehydration – severe female
abdominal cramps
o Rice watery stool C. MANAGEMENT
o Poor skin turgor - Metronidazole
o Sunken eyes
Manifestation Management
(aside from complications (aside from
A. COMPLICATION: diarrhea) ORS/IVF)
1. Acid base and electrolyte imbalance: Rice watery Severe Tetracycline
Metabolic Alkalosis Cholera
stool dehydration
o K - cardiac (violent)
AB imbalance
o NA – neuro Dysentery Blood in stool Dehydration Ciprofloxacin
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COMMUNICABLE DISEASES
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Diagnosis Complication:
- Fecalysis - Intestinal obstruction
- Circumova precipitin test (COPT) o Cluster worms
Management Management
- Anti-parasitic - PURGA
o Praziquantel o Albendazole
o Mebendazole
Prevention o Pyrantel Pamoate
- Snail control 3 days prior – provide patient to take
o Molluscides anti-histamine (target: worms)
o Irrigation
o Snail eating fish Enterobiasis
- Environmental sanitation - Pinworm
o Proper excreta disposal
o Foot bridges MOT
- Direct/indirect contact
- Fecal – oral route
LEPTOSPIROSIS SCHISTOSOMIASIS
Bacteria Parasite (Blood Manifestation
Etiology - Anal pruritus
(Leptospira) flukes)
o Itchy buttocks
Skin Skin penetration
MOT
penetration
Diagnostic test
- Tape test
o Done in the morning (inactive
worm)
Management
- Anti-helminthic
o Family members should be
INTESTINAL PARASITISM
included
PARASITISM
Prevention
- Daily hygiene
MANIFESTATION
- Changing underwear and bed items and
- Voracious appetite
towels
- Weakness
o Bleach and hot water
- Pot belly
o Dry under sunlight
- Anemia
- Avoid nail biting
- Stunted growth
- Hand washing
- Gloves or mittens
Diagnosis
- Fecalysis
Ancylostomiasis
o Purga – high risk for <5 years of age
- Hookworm
(6 months advisable)
o Blood suckers
I. Ascariasis
MOT
- Giant roundworm
- Skin penetration
o Common in soils
MOT
- Fecal – oral route
Manifestation
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COMMUNICABLE DISEASES
- Anemia chronic
- Anorexia
- Fatigue Diagnostic
- Liver enzymes
Diagnostic - Serum Ag- Ab test
- CBC o HbsAg – virus (NR)
- Stool exam o Anti-Hbs – antibodies (NR)
Treatment Management
- Anti-helminthics - Essentiale, Silymarin
- Iron supplements - Chronic HBV: interferon
o Black stool are normal
o Z tract with SQ Nursing Care
- Balance rest and activities
Taeniasis o Rest for liver
- Tapeworm - Nutrition
o Beef o High carbs (simple sugars) and
o Pork protein
o Fish o low fats
- Lifestyle modification
MOT o Remove alcohol consumption
- Ingestion of contaminated meat
SEXUALLY TRANSMITTED INFECTIONS
Management
- Praziquantel GONORRHEA
- Niclosamide - Neisseria gonorrhea
- Related to Chlamydia
HEPATITIS
- Etiology MOT
o A – infectious hepatitis - Various forms of sexual contact
o B – serum hepatitis (DNA – sexually
transmitted) Manifestation
o C – Post transfusion hepatitis - Pyuria
o D – Delta/Dormant HepB o Pus in the urine
o E – Enteric hepatitis - Dysuria
MOT Diagnostic
- A and E = fecal oral route - Gram staining
- B, C, D = blood and body fluids
Complications
stages - Sterility
Pre icteric - Fever, RUQ pain - Pelvic inflammatory disease (PID)
- Weight loss, fatigue - Ectopic pregnancy
- Anorexia, nausea o Women are asymptomatic
and vomiting
Icteric - Jaundice
- Pruritus
- Dark colored urine Management
- Alcoholic or clay - Antibiotic
colored stool o Ceftriaxone
Post icteric - Recovery IM ‘
- Chances are it is o Treatment for chlamydia (doxycycline)
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COMMUNICABLE DISEASES
MOT
- Sexual contact
- Blood transfusion
- Needle pricks
- Vertical transmission (mother to baby)
STAGES
- Painless ulcer
- Heals
spontaneously - CD4 lymphocytes
Primary: Chancre o N: 500-1500 mm/3
with or
without o AIDS: <200 mm/3
treatment
- Flu like sx Manifestation
- Dermatitis* - immunosuppression
Secondary: o Opportunistic infection
- Patchy alopecia
Condylomata The more vulnerable =
- Generalized
lymphadenopathy easy to compromise
- Infiltrating lesions Pneumonia cystis carinii
- CV changes Cytomegalovirus retinitis
Tertiary: Gumma - CNS degeneration Candidiasis (T: Nystatin –
- No longer spit or swallow*)
communicable o Persistent fever
o Chronic diarrhea
Diagnosis o Weight loss
- Blood exam or culture o Lymphadenopathy
- Venereal Disease Research Laboratory
(VDRL) Diagnosis
- Rapid plasma reagin (RPR) - Window period: 2 weeks to 6 months: avg is
3 months (looking for the antibodies)
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COMMUNICABLE DISEASES
Prevention STAGES
- Standard precaution - cough
- Safe sex practices (ABCD) - Cold
- Prophylaxis - Conjunctivitis
o Pre-exposure - Photosensitivity
PRE-ERUPTIVE
2 hours before act- 1 after - Enanthem (kolpik
-1 day after daily spots – bluish
o Post-exposure white spots at
After exposure to high buccal cavity)
risk/confirmed contacts - Exanthem
1 month - Maculopapular
ERUPTIVE
- Reddish
Opportunistic infections - Cephalocaudal
POST- ERUPTIVE - Brownish staining
Kaposi’s Sarcoma
- Vascular endothelium Management
- Purplish lesions (non painful or pruritic) that - Isolation
are flat or indurated o Strict isolation
- AIDS defining disease - Oral care
o Kolpiks spot
Treatment o Gurgle with salt water
- Radiation - Skin care
- Chemotherapy o Calamine lotion
o Anti-histamine
Integumentary Infections o Oatmeal
- Vitamin A administration SQ
Eruptive fevers o 6-11 months (100,000 IU – blue)
- Exanthem o 12 months or above (200,000 IU -
o Outside red)
- Enanthem o Protects the RESPI and GI mucosa
o Inside
- Macule Duration of immunity
o Flat lesion - Lifetime
- Papule
o Raised lesion Prevention
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COMMUNICABLE DISEASES
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Etiology
- Mycobacterium leprae EBOLA VIRUS DISEASE
MOT MOT
- Prolonged, intimate skin to skin - Contact with body fluids of fruit bats,
- contact chimpanzees, gorillas, monkeys
- Human to human transmission
Diagnosis
- Skin slit smear Complication
- Skin lesion biopsy - Hemorrhage
- Peripheral nerve enlargement o High fatality rate
- Loss of sensation
Management
Manifestation - No medication nor vaccine BUT was
- Skin lesion that does not heal controlled due to known source
- Skin lesions spread throughout the body
- Conjunctivitis MONKEYPOX
- Nosebleed - Viral zoonotic disease
- Disfigured face o Squirrels
o Nostril deformed o Rats
o Loss of eyebrows o Primates
o Earl lobe thick and lumpy
- Incomplete eyelid closure (lagophthalmos) MOT
- Deformities in the hands and feet - Close contact
- Paralysis o Lesions
o contractures o Respiratory droplets
- Fingers are amputated due to necrosis o Beddings
- Vertical transmission
Leprosy mgt - Related to smallpox, less contagious and
severe s/sx
OTHER EMERGING INFECTIONS
Manifestation
ZIKA VIRUS - Fever
- Mosquito borne disease; similar vector with - Lymphadenopathy
dengue - Rashes
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COMMUNICABLE DISEASES
Diagnosis
- PCR (skin lesion)
- Self-limiting disease (2-4 weeks)
- Complications (severe
immunocompromised)
o Pneumonia
o Sepsis
o Encephalitis
o Corneal infection may lead to
blindness
Medication
- Tecovirimat
Vaccination
- Attenuated vaccina virus (Ankara strain)
SNAB