MCQs IN CELL PHYSIOLOGY-BY CUTHBERT CHIUYU
1. Factors of the internal environment that must be homeostatically maintained
include;
a) concentration of glucose molecules
b) temp
c) blood pressure
d) blood pH
e) partial pressure of nitrogen in the blood
2. State if the following is/are true or false concerning peroxisomes;
a)they are similar to the Golgi apparatus
b)they contain hydrolytic enzymes
c)they contain enzymes for lipid metabolism
d)they are oval or spherical in shape
e)they produce hydrochloric acid
3. Concerning the components of the biomembrane,state if the following is/are true
a)lipids form upto 90% of the membrane
b)lipids are responsible for membrane fluidity
c)detergents can dislodge lipids from the membrane
d)membrane carbohydrates form the basic structure of the biomembrane
e)they are more proteins than carbohydrates in the membrane
4. The concentration(Mm) of the following ions intracellular are;
a)sodium=5
b)chloride=110
c)calcium=100
d)potassium=4.5
e)magnesium=0.55
5. Concerning Fick’s law of diffusion;
a)diffusion rate is directly proportional to the thickness of the membrane
b)the diffusion rate is directly proportional to the concentration gradient
c)diffusion rate is directly proportional to the area across which diffusion
occurs
d)diffusion is measured in moles/cm2
e)
6. The following ligands have intracellular receptors
a)insulin
b)androgen
c)retinoic acid
d)thyroid hormone
e)cortisol
7. State if the following statements are true/ false;
a)ligands that activate the same signalling pathways usually produce the
same effect
b)Ach induces contraction of skeletal muscles
c)Ach inhibits contraction of heart muscles
d)epinephrine activate glycogen synthesis in the liver
e)G-protein linked receptors constitute the largest family of receptors on the
cell surface
8. True/ false ;
a)epinephrine binds to B1 adrenergic receptors in the heart,and stimulate
adenylyl cyclase
b)epinephrine binds to A2 adrenergic receptors that inhibit adenylyl cyclase
c)vibrio cholera toxin inactivates Gs
d)Bordetella pertussis toxin inactivates Gs
e)cortisol stabilises lysosomal membrane
9. State if the following are true or false about cancer;
a)cystic fibrosis is an example
b)it can not be cured
c)it manifest as proliferation of cells
d)nicotine obtained from tobacco is toxic to cancerous cells
e)at least two mutations are necessary for a cancer to occur
10. The following are second messengers
a)Na+/K+ ATPase
b)diacyglycerol
c)inositol triphosphate
d)mRNA
e)Ca2+ QA
11. Using the information below state if the statements below are true or false ;A cell
containing 150mM KCl,10mM NaCl,1mM MgCl2,and 0,0001mM CaCl2 is placed in a
solution containing 140mM NaCl,5mMKCl,1,5mMCaCl2,2mM MgCl2.
a)the osmolarity of the cell is 300mOsm
b)the osmolarity of the solution is 310mOsm
c)water flows across the membrane into the solution
d)the cell will shrink
e)assuming that normal omolarity is [Link] cell is hyposmotic
12. Carrier proteins found in some biomembranes ;
a)may be uniports if they carry one substance eg Ca2+ ATPase
b)may be symports when they transfer two substances in the same direction
across the membrane. Eg. Na+/Ca2+ symport
c)maybe antiports when they transport two substances in opposite direction
eg Na+/K+ ATPase.
d) attain maximum rate of transport at saturation
e)may be ion channels that are voltage gated
13. The following can diffuse readily down the concentration gradient across the plasma
membrane
a)nitrogen
b)glucose
c)urea
d)glycerol
e)water
14. Regarding the structural levels of organisation ;
a)the most abundant molecules in the cell are C,H and O
b)cellular level is the basic structural and functional unit of an organism
c)organ level is made up of a group of similar cells that cooperate to perform
a common function
d)the heart is an example of a tissue
e)the highest level of organisation is the organism level
15. True/ false
a)GABA is a major excitatory neurotransmitter in the central nervous system
b)both B-adrenergic and A-adrenergic receptors are G-protein linked
c)aquaporins can close or open depending on the type of ligand bound to it
d)normal saline is 90% NaCl
e)opening K+ channels makes the resting membrane potential more
negative
16. True / false
a)CO2 requires the presence of CO2 channels to cross the biomembrane
b)the Na+/K +ATPase transports 3Na+ out of the cell and 2K+ into the cell
c)macrophages take in bacteria for destruction by a process called
phagocytosis
d)the major problem in cystic fibrosis is submucosal glands fail to secrete
mucus
e)blocking G-protein coupled receptors in the enterocytes with an
antagonist help to cure diarrhea caused by vibrio cholera
17. Response(s) to a ligand binding to a receptor can result in;
a)regulation of a metabolic pathway
b)regulation of gene expression
c)changes in the cytoskeleton
d)increase in the activity of plasma protein
e)apoptosis
