Endocrine System Overview and MCQs
Endocrine System Overview and MCQs
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MULTIPLE CHOICE
6. Which of the following is true about
1. Which statement regarding endocrine glands hormones?
is incorrect? a. They are released from exocrine glands.
a. They produce hormones. b. They interact with receptors at target-cell sites.
b. They secrete their products into the blood. c. They are synthesized in the lymph nodes.
c. They are comprised of epithelial tissue. d. They interact with receptors in the blood.
d. They are all controlled by the nervous system. e. They are all similar chemically.
e. They are ductless.
ANS: B
ANS: D
7. Which statement is incorrect?
2. Neurosecretory neurons a. A single endocrine gland may produce multiple
a. release neurotransmitters hormones.
b. release hormones b. A single target cell may be influenced by more
c. are unable to conduct action potentials, unlike than one hormone.
ordinary neurons c. A single hormone can influence only one type
d. perform both a and b of target cell.
e. are found in most endocrine glands d. An endocrine organ may secrete non-endocrine
substances in addition to hormones.
ANS: B e. The same hormone may be secreted by more
than one endocrine gland.
3. The specificity of hormones is due to
a. specialized hormone secretion ANS: C
b. molecular rearrangement at the site of action
c. specific binding of hormones to plasma 8. Select the incorrect statement about peptide
proteins hormones.
d. specialization of target-cell receptors a. They include adrenal cortex hormones.
e. inactivation of hormones by the kidneys b. Insulin is an example.
c. They are stored within secretory granules.
ANS: D d. They are secreted from endocrine glands.
e. They must bind to membrane receptors to
4. Hormones invoke their actions.
a. are all of similar chemical composition
b. combine with specific receptors on the target ANS: A
cell's surface or inside the target cell
c. are secreted at a constant rate 9. Which statement about tropic hormones is
d. all act by activating adenylate cyclase, which incorrect?
transforms ATP into cyclic AMP a. They may stimulate the secretion of other
e. have all of the above characteristics hormones.
b. They target other glands.
ANS: B c. They are all produced in the anterior pituitary
gland.
5. All hormones d. Both a and b
a. are regulated by the hypothalamus e. All of the above
b. initiate synthesis of new proteins
c. are secreted by endocrine glands through ducts ANS: C
into the blood
d. must combine with specific receptors on the
target cells in order to exert their effects
e. are eventually inactivated by enzymes in the
liver, kidneys, blood, or target cells
ANS: E
10. Which of the following is not a function of 15. Which class of hormones are polar and,
the endocrine system? accordingly, hydrophilic?
a. Maintenance of blood sugar levels a. Peptides
b. Regulation of metabolic activity and H2O and b. Catecholamines
electrolyte balance c. Steroids
c. Promotion of growth and development d. Both a and b
d. Transduction of external stimuli e. None of the above
e. Helping the body cope with stressful situations
ANS: D
ANS: D
16. ____________ is/are synthesized by the
11. ____________ is not controlled, at least in endoplasmic reticulum-Golgi complex
part, by hormones. mechanism.
a. Homeostasis a. Peptides
b. Organic metabolism b. Catecholamines
c. Rapid interactions with the external c. Steroids
environment d. Thyroid hormone
d. H2O and electrolyte balance e. Both b and d
e. Adaptation to stress
ANS: A
ANS: C
17. _________ is not a tropic hormone.
12. Tropic hormones a. ACTH
a. are produced by the posterior pituitary b. ADH
b. are secreted only by the hypothalamus c. GIP
c. primarily regulate hormone secretion by certain d. LH
other endocrine glands e. TSH
d. all have non-tropic functions too
e. are the hormones that stimulate athletes to win ANS: B
trophies
ANS: C 18. ___________ is/are not stored in the
secretory cell after being synthesized.
13. Hormones are classified into three types: a. Peptides
a. amines, peptides, and steroids b. Catecholamines
b. amines, steroids, and phospholipids c. Steroids
c. amines, phospholipids, and steroids d. Thyroid hormone
d. amines, free fatty acids, and peptides e. b and c
e. free fatty acids, peptides, and steroids
ANS: C
ANS: A
19. Which class(es) of hormones is/are released
14. Amines are by exocytosis upon appropriate stimulation?
a. chains of specific amino acids of varying length a. peptides
b. derived from the amino acid tyrosine b. catecholamines
c. hormones secreted by the thyroid gland and c. steroids
adrenal medulla d. thyroid hormone
d. all of the above e. Both a and b
e. only a and c
ANS: E
ANS: D
ANS: B
20. The transport of lipid-soluble hormones in
the blood is accomplished by 25. Which class of hormones triggers the
a. loose binding with albumin synthesis of new intracellular proteins within
b. specific binding to plasma proteins the target cell?
c. binding with tropic hormones a. peptides
d. both a and b b. catecholamines
e. none of the above c. steroids
d. thyroid hormone
ANS: D e. c and d
21. Peptide hormones ANS: E
a. are synthesized from modified cholesterol
molecules 26. The most common second messenger used
b. are typically not bound to plasma proteins in by hydrophilic hormones is
the blood a. calcium
c. bind to intracellular receptors at their target b. cyclic AMP
cells c. chromatin
d. typically activate genes to cause the synthesis d. messenger RNA
of new protein molecules e. plasma proteins
e. have characteristics c and d
ANS: B
ANS: B
27. Which of the following is least associated
22. Steroid hormones are with the hydrophilic hormones?
a. lipophilic a. cyclic AMP
b. derived from cholesterol b. protein kinase
c. able to initiate the synthesis of specific new c. adenylate cyclase
proteins within their target cells d. intracellular receptor
d. both a and b e. phosphorylated enzymes
e. all of the above
ANS: D
ANS: E
28. Estrogens, testosterone, cortisol, and
23. Identify all correct statements about aldosterone are all derived from
lipophilic hormones. a. tyrosine
a. They include steroids and thyroid hormone b. cholesterol
b. They bind with receptors located inside their c. phospholipid
target cells d. IGF-2
c. They activate second-messenger systems within e. epinephrine
their target cells
d. Both a and b ANS: B
e. Both a and c
29. __________ do(es) not use a second
ANS: D messenger system.
a. ACTH
b. Steroid hormones and TH
24. Which hormones use second-messenger c. Glucagon
systems? d. Most hydrophilic hormones
a. proteins e. Only a few lipophilic hormones
b. catecholamines
c. steroids ANS: B
d. thyroid hormone
e. Both c and d
ANS: E ANS: C
31. ___________ do(es) not require membrane 36. Which of the following is not shared by both
receptors to invoke cell responses. lipophilic and hydrophilic hormones?
a. Peptides a. Amplification of hormone actions in a cell
b. Catecholamines b. Transport via plasma proteins
c. Steroids c. Regulation of metabolic reactions
d. Thyroid hormone d. Initiation of second messenger systems
e. Corticotropes e. Both b and d
ANS: C ANS: E
32. A hormone’s effective plasma concentration 37. Which of the following situations represents
can be influenced by negative feedback?
a. its rate of excretion a. Hormone A stimulates hormone B; hormone B
b. its extent of binding to plasma proteins inhibits hormone C.
c. its rate of metabolic inactivation b. Hormone A inhibits hormone B; hormone B
d. its rate of secretion inhibits hormone A.
e. all of the above c. Hormone A stimulates hormone B; hormone B
inhibits hormone A.
ANS: E d. Hormone A inhibits hormone B; hormone B
inhibits hormone C.
33. The effective plasma concentration of a e. Hormone A stimulates hormone B; hormone B
hormone is normally regulated by stimulates hormone A.
appropriate adjustments in the hormone's rate
of ANS: C
a. excretion
b. binding to plasma proteins
c. metabolic inactivation
d. secretion
e. binding with target-cell receptors
ANS: D
ANS: B ANS: C
ANS: B ANS: E
49. Which of the following is a neurohormone? 55. The ________ is the target for ACTH.
a. vasopressin a. adrenal gland
b. thyroid hormone b. anterior pituitary
c. growth hormone c. posterior pituitary
d. cortisol d. ovary
e. luteinizing hormone e. pancreas
ANS: A ANS: A
50. The ___________ secretes insulin and 56. Which of the following hormones is released
glucagon. from the hypothalamus?
a. posterior pituitary a. CRH
b. liver b. TSH
c. FSH
80. Growth hormone 85. Growth hormone exerts its effects on growth
a. closes the epiphyseal plate of long bones by
b. promotes hypertrophy and hyperplasia a. stimulating production of insulin-like growth
c. secretion is stimulated by an increased blood factors
glucose level b. directly invoking gene activity
d. is the only factor responsible for governing the c. elevating blood glucose levels
growth of an individual d. increasing fat metabolism
e. increasing thyroid hormone levels 91. The “zona” regions of a particular endocrine
gland do not secrete
ANS: A a. aldosterone
b. epinephrine
86. Dwarfism may be the result of a deficiency c. cortisol
of d. androgen
a. growth-hormone releasing hormone e. any of the above
b. GH
c. somatomedins ANS: B
d. all of the above
e. only b or c 92. __________ is not secreted from an organ
located in the abdominal cavity.
ANS: D a. Ghrelin
b. Thrombopoietin
87. Osteoblasts c. Gastrin
a. secrete the organic matrix components of bone d. Insulin-like growth factor
b. become osteocytes once they become entrapped e. Calcitonin
in the bone that they form
c. are primarily responsible for dissolving bone ANS: E
matrix
d. form cartilage 93. Which association is least appropriate?
e. have characteristics a and b a. lactotrope, prolactin
b. thyrotrope, thyrotropin
ANS: E c. somatotrope, growth hormone
d. gonadotrope, luteinizing hormone
88. ___________ does not increase growth e. corticotrope, cortisol
hormone secretion.
a. Deep sleep ANS: E
b. Exercise
c. A low blood amino acid level 94. _________ has been nicknamed the “love
d. Stress hormone”.
e. A low blood glucose level a. FSH
b. Testosterone
ANS: C c. Estrogen
d. Oxytocin
89. _________ is a masculinizing hormone e. LH
produced from the adrenal gland.
a. Growth hormone ANS: D
b. Androgen
c. Thyroid hormone 95. __________ does not act on its target cell by
d. Cortisol binding with a G-protein coupled receptor.
e. Insulin a. PTH
b. Corticotropin
ANS: B c. Thyroid hormone
d. Somatostatin
90. A(n) ____________ is not a cause of primary e. Glucagon
hyposecretion of a hormone.
a. gene mutation ANS: C
b. idiopathic factor
c. hyposecretion of tropic hormone
MATCHING
d. toxic substance
e. iatrogenic factor
ANS: C
Indicate whether the characteristics below 14. Lipophilic hormone derived from an amino
apply to the endocrine system, the nervous acid
system, or both by writing the appropriate 15. Once synthesized, actively transported into
letter in the blank using the following answer preformed vesicles for storage
code:
a. Endocrine system 12. ANS: C
b. Nervous system 13. ANS: A
c. Endocrine and nervous systems 14. ANS: D
1. Has structural continuity 15. ANS: B
2. Stores hormones for secretion
Indicate the solubility characteristics of each
3. Has an influence on another major control
of the classes of hormones by writing the
system
appropriate letter in the blank using the
4. Secretes chemical messengers that affect
following answer code:
target cells
a. Lipophilic
5. Chemical messengers act at a long distance b. Hydrophilic
from their site of secretion
6. Specificity is dependent on specificity of 16. Steroids
target-cell receptors 17. Thyroid hormone
7. Controls activities that require longer 18. Peptides
duration rather than speed 19. Catecholamines
8. Duration of action is brief (milliseconds)
9. Speed of response is long (minutes to days or 16. ANS: A
longer) 17. ANS: A
10. Cerebral cortex can influence activities 18. ANS: B
11. Has ductless glands that secrete 19. ANS: B
36. ANS: E
37. ANS: A