Lotion
Lotions are aqueous solution and suspension (shake the solution). Lotions
are intended to application to unbroken surface of skin. If it contains
insoluble solid in suspension they are sometime referred to as shake well
before use. On application to skin water evaporate leaving a residue of
medicament on skin surface. Evaporation cools and sooths the skin so
lotions are valuable in treating actually inflamed skin or inflamed areas.
Alcohol enhances the cooling effect and glycerol stick the powder tto the
skin. Most lotion are oil in water emulsion using a substance such as
sterile alcohol to keep the emulsion together but water in oil lotion are also
formulated. The key component of skin is lotion, cream or gel. Emulsion
are the aqueous and oil phasess and an emulsion to prevent the separation of these two phases and
if used the drug substance and substances. A wide variety of othe
otherr ingredients such as fragrance,
fragrance
glycerol, petroleum jellies, dyes, preservative, proteins and stabilizing agent are commonly
common
added to lotion. It can be used for the delivery to the skin of medication ssuch
uch as antibiotics, anti-
anti
septic, antifungal corticosteroid anti
anti-acne agent and soothing, smoothing moisturizing and
protective reagent (such as calamine).
Packaging:
Lotion should be closed with a plastic cap. They should be available for external use only. It is
use as a moisturizer to treat
at or prevent dry, rough and itchy skin. Emollient are substance that
soften or moisturize the skin and decease itching and flaking.
Some product (zinc oxide, white petroleum) are used mostly to protect the skin against irritation
against wetness.
Uses:
Lotion are used as antiseptic, germicidal
ermicidal and used in treatment of skin diseases..
EXPERIMENT NO. 07
Object:
To prepare and dispense with proper labelling 25ml of calamine lotion.
Apparatus and Chemicals:
Mortar and pestle, beaker, measuring cylinder, dispensing bottle, glycerol, calamine, zinc oxide,
bentonite, sodium citrate.
Formula for 1000ml:
Calamine...............................150g
Zinc oxide.............................50g
Bentonite...............................30g
Sodium citrate........................5g
Liquid phenol.........................5ml
Glycerine................................50ml
Water Q.S to produce............1000ml
Formula for 25ml:
Calamine.............................._______
Zinc oxide............................_______
Bentonite.............................._______
Sodium citrate......................._______
Liquid phenol........................_______
Glycerine..............................._______
Water Q.S to produce..........._______
Procedure:
o Weigh sodium citrate and transfer it in mortar and pestle, add small amount of water in it and
then triturate.
o Now weigh calamine, zinc oxide and bentonite.
o Pour the calamine, zinc oxide and bentonite in mortar and pestle and triturate well.
o Now slowly add liquid phenol and glycerine in it and triturate them.
o Now add purified water to make up the volume up to 25ml.
o After dispense it in dispensing bottle and label over it.
Role of Ingredient:
Calamine:
Calamine is used to relieve the itching, pain, and discomfort of minor skin irritations, such
as those caused by poison ivy, poison oak, and poison sumac. This medicine also dries oozing
and weeping caused by poison ivy, poison oak, and poison sumac
Zinc Oxide:
It is used to treat rash and skin irritation.
Bentonite:
Bentonite clay is used to assist in soothing and rebalancing problematic skin, thus restoring it,
making the overall complexion visibly healthier.
Sodium Citrate:
It is used as a buffering agent or alkalinizer (pH adjuster) and a chelating agent.
Liquid Phenol:
Added to modern versions as an additional disinfectant and topical anaesthetic.
Glycerine:
It attracts moisture onto your skin and considered as a humectant. Glycerine is an emollient,
making skin not only moist, but soft and supple to the touch.
Remarks:
