5/18/2015
An open source multi-modality radiation treatment
planning system
Mark Bangert, Hans-Peter Wieser, Eduardo Cisternas, Thomas Klinge,
Oliver Jäkel, Andrea Mairani, Hubert Gabrys, Peter Ziegenhein
Author
Division
5/18/2015 | Page2 provides modular functionality for…
• 3D dose calculations
• Photon IMRT
• Intensity-modulated Proton Therapy
• Intensity-modulated Carbon Ion Therapy
• Inverse planning
• Conventional: physical dose (including MLC sequencing)
• Biological: LQM effect, RBE-weighted dose
• GUI for visualization and analysis
• Base data
• Example patient data (CORT data set) & DICOM Import
• Physical & biological base data for a photon LINAC, a proton machine,
and a carbon ion machine
5/18/2015 |
[Link]
Author
Division
5/18/2015 | Page3 ‘s modular design provides high flexibility…
Load patient data
Set plan parameters
Determine irradiation geometry
Script GUI
Dose calculation
Inverse fluence optimization
Plan analysis
5/18/2015 |
[Link]
Author
Division
5/18/2015 | Page4 script…
5/18/2015 |
[Link]
Author
Division
5/18/2015 | Page5 GUI…
5/18/2015 |
[Link]
Author
Division
5/18/2015 | Page6 uses
• Proprietary scientific computing environment
• Very user friendly
• Ubiquitous in radiation therapy community
• Rapid prototyping capabilities
• Powerful debugging functionalities
• Versatile built-in visualizations
• High efficiency of linear algebra operations
• Interface to CERR possible
5/18/2015 |
[Link]
Author
Division
5/18/2015 | Page7 matRad yields competitive computation
times for realistic patient cases…
# non-zero memory
modality # beams # bixels Tdose calc [s] Tfluence opt [s]
Dij [GB]
photons 5 1164 14.4 106 52.1 11.4 0.2
photons 7 1556 18.7 106 71.7 20.5 0.3
photons 9 1841 21.6 106 81.4 21.8 0.3
protons 1 6334 11.4 106 29.8 26.2 0.2
protons 2 12770 41.9 106 55.1 53.8 0.6
protons 3 19187 72.2 106 81.4 125.9 1.1
carbon ions 1 9806 33.4 106 38.0 23.6 0.5
carbon ions 2 19438 91.0 106 73.1 99.7 1.4
carbon ions 3 29122 148.6 106 112.7 272.4 2.2
Table 1: Computational efficiency of selected treatment planning scenarios for the TG119 phantom.
5/18/2015 |
[Link]
Author
Division
5/18/2015 | Page8 is open source…
• Source code available at [Link]
• Download and start inverse treatment planning right now…
5/18/2015 |
[Link]