MGM INSTITUTEOF HEALTH SCIENCEs,NAVI MUMBAI

2md M.B.B.S.
UNIVIERSITYEXAMINATION,JANUARY 2025

SubjectPATHOLGY -1 Maximum Marks:

100
Duration 3 1lours A
(Scction 30 Minutes,Scction B&C -2 % Hours)

INSTRUCTIONS:
Attemptallquuestios
Masum masks a1e ndicatcdinthe nght
stiatethe answeIswith suntabledagia herevernecessary
Plesesamrender son SVWITCHED
OFF
(4 cellphoIes al cntry pont mto the xamnafson Flall

E
Moble olher
phones. pagers, bluc toothor any such communication devices are nof allowed in the Examinationpremibe
and in the adjacent arca

SECTION-
[Link] 5 out of 6 (SAQ) (5x6 Marks = 30 Marks)

A. Writcmode of healingofa wound by secondary intention.

B. Clinical
fcaturcsand peripheralsmcar findings in multiple myeloma.
C. Classify accumulations. Writebricfly
intracellular about endogenous pigments.
D. Writeabout morphologicaltypesof inllammationand add a note on fateof acute
inflammation.
E. Definepatientautonomy and paternalism. Writedifferences between autononmy and
paternalism.
F. Writeindetailabout the sereeningtestsperformedforselection of blood donor

= 10 Marks)
Q.2Answer any 1 outof2(LAQ) (1x10Marks

A. A 30 yearoldfemalewas brought to the casualty withthe complaintsoffeverand decrease

examinationpulse were weak & rapidwith
urine output forlast3 [Link] clinícal
[Link] was cammy and [Link] culture revealedgrowth of

gram negative bacteria.(1+6+3)

I. What isyourprobable diagnosis?2
Writethe pathogenesis and stages ofthiscondition.
III. you wouldliketo do0?
What other investigations

B. Defineand enumerate of
morphologicalfeatures
the [Link]
malignant neoplasm. (2+2+6)

SECTIONC
Q.1Answer any 5 outof 6 (SAQ (5x6 Marks=30 Marks)

A. Complicatíonsand lab diagnosisofsicklecellanemia.

B. What are the differences
between transudateand exudate? Writepathogenesis ofrenal
edema.
C. Phagocytosis
D. Trisomy21
E. Clinicalfeaturesand etiopathogenesisof systemiclupus erythematosus.
F. Grading and stagingofcancer.

P.T.O
9.2Answerany 1 out of 2 (1LAQ) (Ix10
Marks 10 Marks)

A. A 20 ycaroldancmc lemalepatienthas the MCV-70tl..MCr

indices:
red cell
follwing
22 pg. MCTIC-54n and RDw was within smear reveaico
norallimits. blood
Peripheral

.
microcytosis. hypexhromasa with many target clls.(15*4)

e
Givc your probablc
diagnosis
Writethe ctopathogcnesisand its
types.
Whal othCr you would liketodo to confirmyourdiagnosis:
investigations

B. Fnumerate diflerentbloodgroup systems, Write dinicalfeaturesof mismatched blood

transfusionand investigations
carricdout ina cases ofblood transfusionrecaction.
(2+5+)
 MGM INSTITUTE OF UEALTIISCTENCES, NAVI MUMBAI
[Link] 202.3
2 M.B.B.S. Marks:100
Subjeet Maximum
PAHOL0GV
Duration A 30 Minutes,SectionB & C 2%Hours)
INS IRU iNS
Tlours(Section
eae
PeTsite1Ot
amener vens SMe
tofh
ell
phonrs af entrv

other san hcommunIc

pontntethe F samnatromIla
atom devres ate not allewed inthe
xaminationpretnty
the

E
anv

SECTION -B 30 Marks)
Q.1Answer any 5 out of6 (SAQ) (5x6Marks

A. Morphology of cntericfeverin differentorgans.

B. Plcomorphicadenoma.
C. CSF findingsin diflerenttypesof meningitis.
D. Causes and morphological types ofpericarditis.
E. Defineand write how willyou maintain patíentautonomy?
F. [Link] lab diagnosis of thyrotoxicosis.

= 10 Marks)
Q.2Answer any Ioutof2 (LAQ) (1x10Marks

A. Define risk
acute coronary syndrome? Write in details [Link],microscopicchanges
and complicationsofmyocardialinfarction. (1+6+3)
B. A 30 yearold female presented with single lump in rightupperinner quadrant [Link]

I
is a slow growing, painless mobilelump. Nippleand
and freely areola are [Link]
lump isnot fixedto the overlying skin.(1+3+6)
What isyourprobable diagnosis?
I. What investigationsyou would like
to performtoconfim your diagnosis.
features
What arethe gross and microscopic seen in this
condition.

SECTIONC
Q.1Answer any 5 outof 6 (SAQ) (5x6 Marks
=30 Marks)
A. Clinicalfeaturesand morphology ofhydatidiform
mole
B. What are melanocyticnevi? Write about typesof melanocyticnevi.
C. Write clinical
presentation,gross and microscopyofcarcinomaof prostate.
D. Etiology.
gross and microscopic featuresof Nutmeg liver.
E. Classification
of Hodgkin'slymphoma. Write differentiatingfeaturesof Hodgkin'sand non-
Hodgkin'slymphoma.
F. Definition
and causes of hematuria. Writeurinary inacute post streptococcal
findings
glomerulonephritis.

Q.2Answer any 1 out of2 (LAQ) (Ix10Marks = 10 Marks)

A. Classifypneumonias. Write in detailthe etiopathogenesis,stages,morphology and

complications of lobar pneumonia. (2+6+2)
B. 18 yearsmale with lytic lesionin lowerend offemur and X-rayrevealedsun-burst
with formation of Codman's
appearance, periosteallifting triangle.(1+4+5)
I. Give yourprobable diagnosis.
Writethe etíopathogenesisof the lesion.
Gross and microscopicfeaturesofthis lesion.
 MGM INSTITUTEOF HEALTH SCIENCES,NAVI MUMBAI
2nd M.B.B.S. UNIVERSITY EXAMINATION, JANUARY 2023

Subject MICROBIOLOGY -I Maximum Marks: 100

Duration-3Hours
INSTRUCTIONS: (SectionB&C =2% hrs.)
1. Attempt all

3.
ODiC
questions.
2. Plcascsurrenderyour SWITCHED OFF cellphones at entrypointintotheExamination a
are not allowed
phones. [Link] toothor any other such communication devices
n tne

Examination premises and in the adjacent area

--. ---==--*~---*-
SECTION-B
Shortanswer question 30 Marks
Q.1. 5 outof 6 (5x6)

A. Explain growth curvewithneat labeled

Bacterial diagram.
B. Bacterialspore
C. Workinginhealth care team.
D. Inclusion
bodies
between T and B lymphocytes
E. Give6 Differences
F. Structureand properties
of IgA

10Marks
[Link] Answer Questions1outof2 (1xi0)
a bee with
A. A 45 yearoldfarmerwas brought tothe emergency departmentfollowing sting
H/O
in hishead and [Link]
shortness of breath a poundíng sensation
Intramuscular adrenaline and IV
beingstung by beeson two earlier
occasiions.
[Link] could be the probable clinicai
diagnosisofthis
antihistamines were
reaction.
mechanism and mediatorsof type I hypersensitivity
Describein detail
condition?

about
Write in detail
and disinfection.
B. Definesterilizatíon by dryheat.
Describesterilisation
in Hot airoven.
precautionsand controlused
functioning,

SECTION-C
30 Marks
5 outof 6 (5x6)
[Link]
A. Vaccinationagainst enteric
fever

B. Give6 differences
between Amoebic and Bacillary
dysentery

in India
and discuss laboratory
haemorrhagic feversprevalent
common viral
C. Enlist
fever[DHF]
diagnosis ofDengue haemorrhagic
malaria during the acute phase ofillness
D. Laboratory methods to confirm

E. Infections
caused by Staphylococcus aureus

[Link] StrategiesforHIV testing

P.T.O
[Link] Answer Questions1 out of2 (lx10) 10 Marks
A. A 12 yr Old boy presentcd to pediatric withCO
emergency department during
monsoons

profuse and frequentwatcr diarrheasince the previousday alongwith 2-3 episodesof

1Therewas no H/O fever,
vomiting. abdominal pain,orpassage ofblood instoó[Link]

mentioncdthatsome residentsof the shum were also suffering

from a similar
condition.
Gross examinationofstoolhad a characteristic
"rice
water appearance' and
Hangingdrop
examination ofstoolsample showed bacteriawith dartingmotility.
What couldbe the

probable clinical
diagnosisofthis
condition?
Describepathogenesis and write in detail

about laboratorydiagnosisofabove condition.

B. Classify víruses.
hepatitis Describelaboratorydiagnosis ofhepatitisB virus
infection
 MGM INSTITUTEOF HEALTH SCIENCES, NAVI MUMBAI
2 [Link], JANUARY 2023

ubjeet MICROBIOLOGY -
II Maximum Marks: 100
Duration-3Hours
&C -2.)
.
INSTRUCTIONS:
Attempt allquestions.
OFF cell
(SectionB

phones at entrypointintothe Examination

Hall
Plcascsurrenderyour SWITCHED not allowed in the
such communication devicesare
Mobile phones. [Link] toothor any other
Examination premises and in the adjacent area

---------~-----*
SECTION-B
30 Marks
Write Shortnoteson any 5 outof6 (5x6 Marks)
Q.1.
A. Laboratorydiagnosis ofmeningococcalmeningitis
B. Cryptococosis
C. Write short note on informedconsent
.
D. Tuberculin
test
E. Antigenicshift
& antigenícdrift
F. Enumerate Poliovaccinesand elaborateon pulse poliocampaign.

Mark:10
(Solveany 10ut of2):(1x10marks)
[Link] Answer Questions
cough forpast
two
low grade feverand productíve
A. A 50 yroldman presentedwith H/O chest revealed nodular
of His X-ray
months. He also gave a H/O lossof wt and loss appetite.
for fast bacilli.
inrtupperlobe.
infiltrate The sputum smear was positive Acid
condition?
i]What is probable clinicaldiagnosis of this
in diagnosisof thiscondition
iiWrite detailabout laboratory

pathogenesis and lab diagnosisofPlague in

B. Enumerate agents ofzoonotic infections.
Explain
detail.

SECTION-C

Mark: 300
[Link] on any 5 out of (5x6marks)
6

A. of leptospirosis
Laboratory diagnosis
B. Aspergillosis
C. Microbiologicalexaminationof water
D. Morphology& pathogenicity of Candida albicans

E. Universalsafetyprecautions
care associatedinfections
[Link],causativeagents and preventionof health

1 Out of2) :-1x10marks) Mark:10

(Solveany
[Link] Answer Questions
[Link] had a H/O
A. A 20 yrold man presented with purulent urethraldischarge and
[Link] examination ofgram stained smear of the discharge
unprotected sexsevendays found.
intracellular
gram negative diplococcicalong with abundant polymorphswere
diagnosisof this condition?
i]What is probable clinical this condition
ii]Writein detailabout laboratorydiagnosis of

agents ofurinary tractinfections(UTI).

Givepredisposing
factors for
B. Enumerateetiological

[Link] diagnosisofUTIindetail.
 MGM INSTITUTEOF HEALTH SCIENCES,NAVI MUMBAI
2 UNIVERSTTY EXAMINATION,JANUARY 2023
M.B.B.S.

Subject-PHARMAOLOGY - I Maximum Marks:100

Duration
INSTRUCiONS
3llours A
(Scction 30Minutcs,ScctionB&C- 2% Hours)
rtempt allqurnet
AIIas muans mdnc nted m tlhe rigeht
ame
umnamm
atictthe nunswers wath satfable w he fevet ne essary
Nlnstn
[Link]
en temden pheTEPage
som SWTe ED
beat tooth or
OFF
ams
ell
phenes at cntes pount nto the I xaminafson 1fall
F
le
othersanchcormmamscafuen devEes are notalowedn the xammaniom premuses amd m theadjacent area

SECTION-B
[Link] Short notes on any 5 outof6 (5x6 Marks) 30 Marks

R blockers.
A. Classify Discuss thcirindicatíons
& adverse effects
B. Enumerate AngiotensinC'onverting Enzyme (ACE) inhibitors. indications
Discusstheir &
adverseeffects.
C. Discussvarioustypesofdrugantagonism with examples.
D. Classify
[Link] advantages ofLow MolecularWeight Heparins
(LMWH) over unfractionatedHeparinmolecule.
E. Classifyanticholinesterases.
Discussthe treatment of MyastheniaGravis
F. Enumerate the parenteralpreparatíonsofIronand discusstheir indications.

(Solveany 1 Out of2):(1x10marks)

[Link] Answer Questions 10 Marks

A. A 45 yearoldmale farmercame tothe emergency unitwiththe complaintsof

salivation
breathlessness,[Link] and ofvision.
blurring On examinatíon
following findingswere noted: Hypotension,Bradycardia, ofpupil.
constriction His
relatives
givehístoryofaccidental inhalationof chemicalwhileworking inthe farm.
What isyourdiagnosis
Enumerate drugs tobe used in management ofthispatient
(includingdose & route)
iii. Explain
the supportativecare

iv Explainthe roleofantidote.
B. Classify Discussthe treatment of myocardialinfarction.
antianginaldrugs.

SECTIONC
WriteShortnoteson
Q.1. (5x6 Marks) any 5 outof 6 30 Marks
A. Givethe treatment of hypertensive
emergencíes
B. Discussthe cardínal signsofBioethics
C. Discussthe mechanism ofaction & uses of nondepolarizing neuromuscular blockers.-

D. Enumerate chelating [Link] two ironchelators in

details.
E. Discussany 5 examples of drugs having ocularside effects.
F. Discussthe importance of plasma proteinbindingof drugs.

(Solveany 1Out of2)(1x10marks)

[Link] Answer Questions 10 Marks

A. A 40 yearoldfemale presented seversepigastric pain the discomfort. She was

on
treatment
with pain killers
for her knee jointpain for the past 2 weeks. She also a of
give history
medications for her high blood pressure and high blood sugar levels sincethe past 3
taking
[Link] was unable totake any food due to severe nausea.
i. What isthe diagnosisof thiscondition?
Identifyand explainthe precipitating factor for pain?
severe epigastric
Classify drugs used in the management of this condition?
iv. Explain the mechanism of actionand other uses of preferred drug for thispatient?
B. Discussthe types and theirpharmacotherapy.
ofglaucoma
 MGM INSTITUTEOF HEALTH SCIENCES,NAVI MUMBAI
UNIVERSITY [Link] 2023
2nd M.B.B.S.

SubjectPHARMACOLOGY - Maximum Marks: 100

Duration- 3 Ilours(SectionA SectionB&C
30 Minutcs, 2 % Hours)

INSTRUCTIONS:
tcmptallquestreons
(2 Masmum marks are mdicated n the right
ate the annerswth
llest sutabledragrams wherever netessary
(4 PMease surender sour SWITIED OFF cellphones at entry posnt
mtothe Fxamnation FFall
not aillowed in the F-xamnafron
phones. pagers, hlue tooth or any other such devices premises
Mebvle communicatsom are

and in thc adjacent arca

SECTION-B
WriteShortnoteson
Q.1. any 5 outof 6 (5x6 Marks) 30 Marks

A. Classify
[Link] & contrastPropylthiouracil& Carbimazole.
merits& demeritsof adding a peripheral
B. Discussthe rationale,. decarboxylaseinhibitor
to

Levodopa for Parkinsonism.

C. Discussthe mechanism ofaction & adverse effectsofEstrogen& Progesterone containing
hormonal contraceptives.
D. Discuss
the mechanism ofactíon,
uses & adverse effects of Ketoconazole.s
Discuss
E. ClassifyFluoroquinolones. the indications
& adverse effects
of Ciprofloxacin.
F. Discuss the roleofInformconsentand refusalof informconsent

[Link] Answer Questions(Solveany 1 Out of2)(1x10marks) 10 Markss

antituberculardrugs. Statethe rationaleformultidrug

A. Classify therapyoftuberculosis
and
describethe mechanism of actíon and adverse effects
of first
lineantituberculardrugs.

B. A Diabetíc patient
receiving [Link]ínunderwentunaccustomed exercise and suddenly
tremors,b lurred weakness
vision, and confusion.
developedsweating palpatatíon,
What does the clinícalpicturesuggests
How to manage thiscase
111 What are the indicatíonsand adverseeffectsofinsulin
iv What are the advantages ofnewer insulin?

SECTIONC
WriteShortnoteson any 5 outof6 (5x6 Marks)
Q.1. 30 Marks

ofMorphine.
A. Writea note on indicatíons Describeits
use inacute left failure
ventricular in
details.
B. Compare & & Benzodiazepines.
contrast Barbiturates
ofMetronidazole.
C. Give the mechanism ofactíon & indicatíons
D. Describethe mechanism ofaction and therapeuticusesof benzodiazepines.
E. Classify Describethe therapeutic
HI antihistaminícs. uses of antihistaminics.
F. Classifydrugs used intreatmentofbronchialasthma. Describeany one antiasthma drug

statingitsmechanism and adversedrug reactions:

ofaction

P.T.O
 (Solveany 1 Out
[Link] Answer Questions of2) -(1x10marks) 10 Marks

A. Describevariousmechanisms ofantimicrobial suí[Link]

resistancegiving
ofdrug resistancc.
the methods for prevention

B. A 35yearoldmale came withcomplaintsof feverwith rigors since last3 days, body ache
and malaise since last2 days. Therc is no historyof burningmicturition and he isdiagnosed
withchloroquine resistantP. Falciparummalaria.
i. Enumeratevariousantimalarialdrugs for this
condition.
1. Which ofthem is the drugofchoicefor thispatient? Describethe dosage regimen
ofthe same drug.
[Link] the rationaleforuse
ofthisdrug in treatmentofchloroquine resistantmalaria.
iv. Discussthe mechanism and adverse effectsofany two antimalarial
drugs.
 MGM MEDICAL
COLLFGE,NAVI
Prelimnary Examination,IInd MUMBAI
MBBS (Phase-11(
Subjecet P4TVOLOGY-I BME Bateh:2022)
Duration A
Hours(Section
INSTRUCTIONS: 30Mins.) Maximum Marks:100
Date: 16.12.2022
(
Attemptall
questions.
Ncbiic phones. [Link] toothor
any othersuch
premises and inthe adjacentarca communication devices
arenot allowed inthe
********ww. bxaminatim

SECTION-A
Q.1.
Multiple
Choice Questions
20 x=20Marks
1. Which
ofthe followingare vitaminK
a) IX.X. XI. dependent clotting
factors?
XII
c) [Link].X b)I1
V 1X, X
d) VIII,
IX,H, V

Which ofthe
followingisNOT an
a) example ofcellular
adaptation?
Hypertrophy
b) Hyperpasia
Dysplasia d) Metaplasia

3. There is
protectí[Link]
in cases of:
a) Irondeficiencyanemia
c) Anemia of chroníc
disorder
b
Sicklecellanemia
d) Megaloblastic anemia
4. Which ofthe
followingbestdescribes
Karyorrhexis?
aShrinkageof nucleuswhich appearsshrunkenand deeply
b) Progressive basophilic toinkdrop)
(similar
fadingof basophilic ofthe nucleiand leadsto a
c) Nucieus breaks staining nuclei
up into ghost
many smallerfragments-
d) Increased
eosinuphiliain cytoplasn

5. Which ofthe following

type of necrosis
occursinkidneyinfarct?
a)Liquefactíve b) Coagulatíve
c)Caseous
d) Fibrinoid

6. Which ofthe followingorgan isnot

affected
by Tuberculosis?
a) Hands
b)Ascending colon
Eye d) Thyroid

fa personis O negativethenRBC
clumps willbe seen in
a) A, B and D
b) A and DD
c)D only
d) No clumps seen.

Which ofthe following

has antí-thrombotic
activity?
a Von Willebrandfactor b) Tissuefactor
Thrombomodulin c)Platelet factor
activating

9 Hemophilia isan example off

a) XLinked recessíve disorder b) X Linkeddominant disorder
e Autosomal dominant disorder
d)Autosomal recessivedisorder
 of
10. What is the value hacmoglobin eligite
[Link] donation?
a) l Igm dl 11.5gm/di
c)12 gm di d)12.5 and above

She nas
11.A 15-ycar-old glhas
episodesof [Link] eyes and running nose for 2weeks.
ier

similarattacks each spring

and Summer when the amount of
pollen in the air is high.
to be mediatedby thereleaseof which of the followingmediators?
svmptoms aremost likely
factor
a) Complement C3b b Platelet
activating
d) Histamine
e)Tumor necrosisfactor

of Hacmolytic anaemia,except:
[Link] thefollowingarefeatures
a)
Splenomegaly
b)Schistocytes
count
d) IncreasedRetículocyte
Macro-ovalocytes

see:in
13. Translocation CML is:
b) t 8:14

c)i:18 d)t11:14

intention?
[Link] of the followingis an example ofwound healingby Primary
wound margins by
Suturesareused
forappositionof margins
a) Irregular
c) Resultsin Irregularcontractedscar d) Infectíon and suppurationis common

15. Which of the followingisNOT a reactive

oxygen species:
a) Superoxide b)Hydrogen peroxidee
d Glutathione
c)Hydroxyradicai

16. Lifespen ofplateletstorageis

a) 10 days b) 15 days
c)2days d) 5 days

and gíantcellsare derívedfrom:

[Link] granuloma,epithelioid
a

a) B lymphocytes b) Mast cells

cMonocyte-Macrophages d) T lymphocytes

involvementof aortaisobservedmostly in:

18. Syphilitic

a) Ascending aorta b) Archofaorta

c)Descending aorta of aorta
d) Bifurcation

19. Smoking is the causativefactorin the followingmalignanciesexcept:

a) Intestinalcarcínoma b) Lung carcinoma

c)Bladder
carcinoma d) Laryngealcarcinoma

disorderdue tomutatíonof glucocerebrosidase

[Link] recessive (GBA)gene is:
a) Gaucher'sdisease b) Neiman-Pick's
disease

c)Hunters disease d)G-6-PDdeficiency

 MGM MEDICAL COLLEGE, NAVI MUMBAJ
Year MBBS CBME Batch 2022--PATHOLOGY
Paper
PreliminaryExamination2022
te:16.1.
2022
Time: Marks:190
ST. UCT:CNS: 10:00am 1:00pm Total
Alcnpt alluestions
inthe right
Maximum marks are indicatcd
the answersS With
llustrate suilable
diagrains wherevernecessary
4. Pleasesurrenderyour SWiTCHHED OFF cell
phones at entry pointintothe ExaminatíonHaill
5. Mobile phones. pagers. biue tooth
or any other such communicationdevicesare notallowedinthe Examinatio
premisesand in theadjacentarea

SECTION-B
02. ShortAnswer Question(AttemptFIVE out of SIX) (5X 6=30 Marks)

a)Differencebetween hyperplasia& hypertrophy

withexamples
b) Pathology of aging
c)Paraneopiastic
syndromes
d) Hypoxiccellinjary
e) Endogenous pigments
) Writeimportanceofcommunication
skillinclinical
practice

Q3. Long Answer Question(AtfemptONE outof TWo) (IX10=10Marks)

a) Define [Link]& Writeetíopathogenesis ofthrombosis .Writeitscomplications.(2+3+3+2)

b) A 20 year oldmale complains of fever,cough with expectoratíom of
& lossof weight with evening rise
temperature since 3 months. X ray showed cavityinupper lobe of [Link] gave similarcomplains in the family.
(2+2+4+2)
[Link] isyour diagnosis?
[Link]
of your diagncsis.
& of the lesion.
[Link] grossfindings
4. Write
complícations.

SECTION-C
Q4. Short Answer Question (AttemptFIVEout ofSIX) (5X6=30 Marks)

Write a shortnote on Klinfelters

syndrome
a)
b) Wound healingby primaryintention
c)Type IHypersensitivityreactíon
d) Pathogenesisofseptícshock
e) Writeetiologyand morphologicalfeaturesofCVC Lung
9Pathogenesis ofHIV

[Link] Answer Question(AttemptONE out of TWO) (IX10=10Marks)

a)[Link] differences
between benign & malignanttumcurs?Describeindetailabout
are the
pathogenesisof neoplasm.(2+3+5)

offatigue.
b) A 22 year old pregnant femalecame with history ofskin& sclerawith
generalisedweakness. pallor
changes in shape of nails(spoon shaped). Lab findings-Hb-8gm/dl,
TLC-8O00/cumm, platelet count-2 lac/cmm,
peripheralsmear shows microcytes+t & hypochromic RBC'S. Prussianblue reactioncn bone marrow showed
deficíentretículoendothelialironstores. (2+3+5)
1. What isyour diagnosís?
2. On what basisyou concluded your diagnosis?
3. What further testsyou willdo to confirm your diagnosis?
--- ----------
 MGM MEDICAL
COLLEGE, NaVI MUMBAI
PreliminaryExamination,
Ind MBBS
(Phase-IICBME Batch: 2022)
Subject -PATHOLOGY -I1
Duration-3Hours
(SeetionA =30Mins.) Maximum Marks:100
INSTRUCTIONS: Date: 17.12.2022
(1)Attempt2ll
questions.
9Mobilephones. [Link] toothor any other such communication devicesare not allowed in the
premises and inthe
adjacent area Fxaiauo

SECTION-A
Q.1.
MultipleChoice Questions
20 x 1=20 Marks
[Link]
plaquc do not contain?

a) Platelets
D Neutrophils
Smooth muscle fibers Monocyles
[Link] skin lesionin
vesselsisseen in?

-a) Malignant hypertension b)Benignhypertensionpattern

c)Peripheral vascular
disease d) None of the above

3. Periphcral of nucleiand peritumoralcleftingisseen in

palisading

a) Squamous cellcarcinoma b)Melanoma

b) Basal celladenoma ) Basal cellcarcínoma

4. Sequentialarrangement typequestion
Sequence of morphological changes inmyocardial infarctíon
frombeginníng:

1)Waviness of fiber
2) Dense cellagenousscar
3) Mitochondríalswelling
4) Earlygranulationtissue

Optionsare
a) 1.2.3,4. b)2,3,1,4
3.14.2. d)2,3,4,1
[Link]
are obstructive
lungdiseaseexcept?

a)Emphysema 5)Interstitial
fibrosis
c)Asthma d) Bronchitis

6. AoroiI
bodíes are seen in?

a) Sarcoidosis b) Syphilis
d) Asthma
Chromoblastomycosis

ofprimarycomplex incongenitaltuberculosisis-
7. Most common site

a)Lungs b)Stomach
Liver
c)Lymph node d)

of
8. Broadcast inurineischaracteristíc

a)CRF b)Acute glomerulonephritis

c)ARF d) Renal Tuberculosis
 [Link] common cause
ofnephrotic
syndrome inchildren:
a} Membranous
c) Post Gilomerulonephritis
GN
streptococcal
K Minimal change disease
d) Rapidlyprogressive
glomerulonephritis
[Link]
isa meosure of
a)Conjugated bilirubin
b) Deltabilirubin
Unconjugated bilirubin d) Conjugated + Unconjugated bilirubin
[Link] followingare CSF
findingsinasepticmeningitis
except?
a) Increased
proteins b) Sugar normal
Ncutrophilia d) Decreasedchloride

[Link] renaldiscase,albumin isfirst

toappear in urinebecause?

a)Of itshigh concentratíoninplasma

bj has molecular
weight slightlygreaterthan the moleculesnormallygetting
filtered
c)High alibumin: globulinratío
d) Tubular epithelial
cellsare sensitiveto albumin
[Link] istrueabout barret's
esophagus?

a) Squamous metaplasia b)Affectsmiddle 2/3d ofesophagus

cYCoiumnar metaplasia d) Malignant

[Link]
ofthefollowing
are trueabout ulcerative
colitis except-

a,Rectum involved b)Pseudo polyps

c)Pancolitis
J Non-caseatinggranuloma
[Link]'sdisease ischaracterized
by
serumceruloplasmin
a)Increase b)Decrease copper excretíoninuríne
AIncreasecopper in liver d) Autosomal dominant

16. Nutmeg liver

isgrossappearance ofliver
inone of the following:

a)Cirrhosísof liver b)Hepatoma

c)Metastasisin liver
d Cironicpassivecongestionin liver
lesion
[Link] the pathognomoníc of which ofthe following
condition?

Multiple myeloma b)Cystinosis

c)Gout d) Osteoarthritis

[Link] most common tumorarising

at themetaphysisoflong bones is:

a) Giantcelltumor b)Ewing'ssarcoma
Osteosarcoma d) Chondrosarcoma

19. Schiller-
duval bodies are seen in

a) Teratoma. b)Seminoma
Yolk sac tumor d) Choríocarcinoma

[Link] largest
ovariantumoris seen with-

a) Mucinous cystadenoma b)Serous cystadenoma

c) Papillary
cystadenoma d)Dysgerminoma
 MGM MGDICAL COLLEGE, NAVI MUMBAI
I Year MBBS CBME Batch 2022
PATHOL0GY Paper I
PreliminaryExamination2022
Date: 17.12.
2022
Tim[Link]m 1:00pm
INSTRUCTIONS: Total
Marks:100
Auempt allquestions
Maximum marks are indicated
inthe right
Tllustrate
the answerswith suitablediagrams wherever
necessary
Pleasesurenderyour SWITCHED OFF cellphones at
entry pointintothe ExaminationHall
5. Mobile phones. pagers, blue tooth or any other such
communicationdevicesare not allowedinthe Examination
premisesand intheadjacentarea

SECTION-B
Q2. Short Answer Question(Attempt FIVE out of SIX) (5X 6-30Marks)
a) Pathophy siologyofCor pulmonale
b) Malabsorptíon
syndromes
c) Hodgkin'sLymphoma
Lab in Hepatitis
investígations
e)Giant celltumour ofbone
of patientsand doctorsinshareddecisionmaking.
fResponsibilities

[Link] Answer Question(AttemptONE out of TW0) (IX10

=10 Marks)

a)DefineBronchiectasis.
Writein detailabout itsetiopathogenesis,
morphology. complicationsand itsprogressiorn
(2+6+2)
b) A 50 year male presentedwithdysphagia sincesixmonths Endoscopyrevealedan elevatedmass in the antrum
with heaped up borders& centralulceration. ieft
Clinically lymphadenopathy. (1
supraclavicular +4+5)
1. Write your diagnosis.
[Link] the Pathogenesis.
[Link]&& microscopy of ihelesion.

SECTIONC
Q4. ShortAnswer Qaestion(AttemptFIVE out of SIX) (5X 6=30 Marks)

a) Carcinoid Syndrome
b)Kidneyin SLE
c) Alcoholiccirhosis: Causes & morphology

d) Endometriosis

e)MorphologyofMeningíoma
Causesofsplenomegaly

Q5. Long Answer Question(AttemptONE out of TWO) (1X10=10Marks)

a)Classifyovarianneoplasm. Describe [Link] & microscopyof mucinous & seroustumours

ofovaryin detail.(4+3+3)
with illdefinedbreastlump fixedio underlying
b)A 60 year female presented muscle. The axillarylymph nodes

were [Link] thefollowing: (2+2+3+3)

1)Wlat isyour diagnosis?

2) Discuss pathogenesis.
5) Describe histological
types.
in thiscondition.
4)Add a note on prognosticfactors
***
 MGM INSTITUTEOF IIEALTHSCIENCES,NAVI MUMBAL.
2 MBBS CBME BATCIH

PreliminaryExamination,DECEMBER 2022

Subject:MierobiologyI Marks:McQ20+B+C80=100
Month Year:December 2022 14.12.22
Duration:1/2hr
SECTION-A

Putadarkcircle OMR sheet on thecorreetanswer Ix20-20

MCQ on

of freeDNA
1) Mechanísm ofdírecettransfer
a) Transformation c)Conjugation
b) Transductíon d) Transposition

2)Following are the exotoxinsEXCEPT

a) Botulinum Toxin c)DiphtheriaToxin
b) Anthrax Toxin d)LipidA portionofLypopolysaccharide

3) Ina patientwithtyphoiddiagnosisafter8 days ofonset offeverisbestdone by

a)Blood culture c) Stoo!culture

b)Urineculture Widal test

4)Leishmaniadonovanican be cultivatedin
a) BloodAgar c)Diamond'sMedium
b NNN Medium d) RPMI Mcdium

rice
5) Food poisoning associatedwith contaminated with Chinese fried
a)Staphylococcusaureus c) Clostridiumperfringens
cereus Vibriocholerae
Bacillus d)

6) Which partofthebacteria
ismost antigenie?

a) Protcin e)Carbohydrate
b) Lipid d) NucleicAcid -

7)Antibodythatmediates mucosal immunity

lgA c)igG
b)lgE d) lgM

infectiousitems should be segregatedin which color-codedbag?

8) Plastic
a) Yellow c)Black
b) Red d) Blue

causes
9) Which stageofmalarial
parasite relapse
a) Sporozoites c)Trophozoites
d) Merozoites
Hypnozoites
0 allare trueEXCEPT.
Staphyiococeus aurens enterotosin,
a) Prefemedtoxin c)Toxinstimulates center
the vagus nerveand vomiting ofbrain
shovt(1-6hr)
D Incubaticnperivd'is Tt ismainlyby carlyinstitution
ofantibiotics

l)Tetranucleate formof
cystsare infeetive
a} Entamocba histolytica c)Leishman donovani
5) Hook wcrm d) Malariaparasitc

12)Highestrisk ofHIV
oftransmission
) Sexual c)Needlc Syringe
Prouluct d)Mother tofetus
bIBlood

skin testisindicatedby
tubereulin an of
area ofindurations
13)A postive
a)<5 mn c)6-9 mm
b)>10 mm d) No indurations

is
hostforEchinococcosis
14)Definitive
a)Man Dog
b) Sheep d) Pig

tritura
15) The common name of Trituris
a) Pinwornm c)Roundworm
b) Hookworm- dWlipworm

route
virusthat spreadsby Fecal-Oral
i6)Hepatitis C
A c)Hepatitis
Hepatitis
B d) D
Hepatitis
b) Hepatitis

is
method of diagnosisof Helicobacterpylori
testsis/are
17) Which of the following
c)Urease breatihtest
a)Warhin-Starry silverstainingg
d) Allof the above
b)Biopsy urease test

18) Maltafeverisalsocalledas
fever c)Relapsingfever
a) Undulant
d) Hemorrhagicfever
b) Rat bitefever

Taenia saginata is
19) The larvalformof bovis
a)Cysticercus cellulose Systicercus
a) Hydatidcyst
b) None of the above

test
best diagnostic is
Periodof patientw ithAIDS, the
20)Duringthe Window c)Westerm Blot
a)ELISA d) Rapid test
b)RT- PCR
 MGM INSTTUTE OF IEALTHSCIENCES, NAVI MUMBAI.
2 MBBS CBME BATC
2022
PreliminaryExamination,DECEMBER
Softtissue & Musculoskeletal,
General,immunology, CVS & Blood,GI,Hepato-biliary,
Module 2.4
1 Marks:McQ20+(B+C)80=100
Subjeet:Mierobiology
Month /Year:
December 2022 14.12.22
hours
Duration:3

SECTION B
5x6-30marks
WRITE SHORT NOTES (Attempt any 5/6)

between Mutationaland TransferableDrug Resistance

1. Enumerate 6 differences team?
as a leaderin a health care
What isthe roleof a medical graduate
2. Why team work isimportantinmedical profession?
Reaction
3. Writea note on Type I Hypersensitivity
of Malaria.
4. Laboratorydiagncsis
5. Writea note on Typhoid Vaccine of Gas Gangrene.
Gas [Link]
6. Enumerate themicro-organismscausing

IXIO=10marks
LAQAnv 12 has rice
since2 days. Stoolcollected watery
diarhea(12-15times)and vomiting
I.A7 Year old boy developedseverewatery of same family
of the same locality
and few children
members
itwas found that two other
On takingHistory,
type of appearance. lastwek.
also suffcred from similarpresentation
What isyour probabieclínical díagnosis?(1M)
(3M)
What isthe etioiogieal agent and Pathogenesis?
in detail.(4M)
Describe the Laboratory Diagnosis
agent? (2M)
aecording to the etiological
What are the treatmerntmodalities
infection
Lab diagnosisof HIVAIDS (4)
and
oftransmission Pathogenesis(4),
[Link] Morphology (2)Mode

SECTIONC
5x6-30marks
any 5/6)
WRITE SHORT NOTES (Attempt

Writeanoteon Autoclave
between Taenia solium and Taeniasaginata.
[Link] 6 differences Filariasis.
3. Laboratory diagnosisofLymphatic caused by Candida.,
of Candida. Name diseases
4. Enlists pathogenic species
dificrent aureus
MRSA (Methicillin ResistantStaphylococcus
[Link] noteon
6. DescribeGraftvs Hust reaction.
ix10-10

LAQ Anv 1/2 His parents revealedttat two children

over the lipsand buccalmucosa.
i Childaged 7 yearsdeveloped
multiple

of hisschoolhad similarpresentation
painful vesicles
few days back. Scrapingstaken
from the lesiondemonstrated presence of multinucleated

giantcells(Tanck Cells).
with reason(2M)
What isthe most probable diagnosis Manifestations of thisdisease(4)
& Clinical
indetails the pathogenesis
Deseribe of thisconditions(4)
diagnosis
Deseribe ihe detailsLaboratory
Fever(4)
agents of
PUO (4)and Lab díagnosisofEnteric
PUO (2). Describethe etiological
2) Defir.
 NAVI MUMBAl.
MGM INSTITUTEOF HEALTH SCIENCES,
2P IBBS CBME BATCIH
2022
Examination,
DECEMBER
Preliminary

Marks: MCQ20+B+C80-100
Microbiology
Subject: 1 December 2022 15.12.22
Month Year:
Duration: 1/2hr
SECTIONA

I20-20
answer
sheet on thecorrect
Put a darkcircleon OMR
MCO media?
culture
on which of the following
[Link]
colony morphology
1) Mercury drop appearance
c)Chocolateagar
a) Bloodagar
d) Nutrient
agar
-Lowe agar
Regan

caused by
sorter"s disease is aureus
2)Wool c)Staphylococcus
anthracic A
aBacillus d) Streptococcus
b) Yersinia
pestis

iscaused by aureus
3)Scarletfever c)Staphy lococcus
A
Group d) Enterococcus
a)Streptococcus
diphtheria
b)Corynebacterium
except
infection
allofthe viral
seen after
isa complication
4)Reye'ssyndrome e Varicellazoster
B
Influenza
a)
A
Influenza dMeasies
b)
by [Link]
affected
siteismost commonly
5)Which of
the following
c) Conjunctiva
a)SSkin
\dýFaucial
b) Kidney

is due to?
infectedbirth canal
acquired through
meningitis strep:
6)Neonatal c)Viridans
pyogenes
a) Streptococcus d} [Link]
b) S pneumonia
isseen
stickappearance
with drum c) Cibotulinum
7)Spores
aCLetani d) C1-perfringes
b) CLdiflicile

iseaused by
mouth disease
foot-and- virus
8) Hand- c)Coxsackia
aiSV d) Chickenpox

b) Measles

by
isidentified
9)Rabies )Negribodies
budies
a)Guarneri bodies d) Cowdry
bodies
b) Paschen
 eseretedin the faees of
Docystof Tovoplasm gondiiare
c)Sheep
bHuman dy C'atle

for procewing ofurinesample

)Whicheulturemedium ispreferrcd
a) TCRS CLE) agar
agar

b)hoculateagar d XiD agar

12)Which isfalse about Bacterial

vaginosis
cCluccellsare diagnostic dia trachomatis
a) Dischargehas otfensivesmell Causatine isChlaiy
d) agent
b)pH45

is correetabout prions?
13)Which of the following
autoclaving c)Longincubationperiod
a)Destroyed by
d) Immunogenic
b) Nucleicacidpresent

of is
14) The causativeorganism Donovanosis
c) Klebsiella
granulomatis
a)Chlamydia trachonmatis Haemophilusducreyi
d)
bMreponema pallidum

common eause ofvulvo vaginitis

!5) The most cTrichomonas vaginalis
coli
a) Entamoeba
d) Entamoeba histoityca
Giardiaintestinalis
b

caused by
iscommonly
16)Viral
keratoconjuctivis

a)
A
Hepatitis )
HepatitisC
d) Herpes virus
b)HepatitisB

iscommonly caused by
keratitis
17)Mycotic Mucor species
species
a)Aspergillus d) Candida
b) Rhizopus

feveriscaused by moniliformis
18)Rat bite c)Streprobacillus
recurrentis
a) Borrelia Yersinia pestis
-d
b) Leptospira

of
feature
isa characteristic
staining
19) Bipolar c)Proteus
Yersiniapestis d)Klebsicla.
b) Shigeila
of
bodies area diagnostiefeature
inclusion virus
20) Owl'seye appearance éCytomegalo
Virus d) HBV Virus
a)Rabies
A virus
b) Hepatis
 MGM INSTITUTE OF IIEAITH
SCIENCES,NAVI MUMBAL
2 MBBS CBME BATCH

PreliminaryExamination,DECEMBER 2022

CNS, Respiratory GenitoUrinaryTract&

TraetInfection& STI,
Zoonotic&Miscellaneous,Actcom2.5
Sebject:Mierobiology Il Marks:McQ20+(B+CJ80=100
Duration:3 hours Month Year:December 2022 15.12.22

SECTION-B

WRITE SIORT NOTES (Attempt any 5/6) 5x6-30 marks

[Link] [Link] differenttypesof HAI,Writea note on Preventionand ControlofHAI

What you mean by Autonomy. Writea note on ContrastAutonomy?
do

3. LaboratorydíagnosisofUTL.
4. Writea note on Post Exposureprophylaxisagainst Rabies.
5. Writea note on Standard Testsfor syphilis.

[Link] the bacteriacausingZoonotic [Link] Leptospirosis.

IX10-10marks
LAQ AnY 1/2

A 28-Year-oldmale was admittedto the hospitalwith complaintsof [Link] more

than 2 [Link] [Link] beaded acid-fastbacilli

What isyour probable

clinical (1M)
diagnosis?
Deseribe Pathogenesisof thiscondition.(3M)
Describe the LaboratoryDiagnosis in detail.(4M)
Writea note on recentadvances in diagnos isof thiscondition.(21)

2. DescribeMorphology (2).Mode Pathogenesis (4)and Lab diagnosis

of transmission, ofpyogenicmeningitis
(4).

SECTION-C

516=30marks
WRITE SHORT NOTES (Attempt any 5/6)

.Write on Non-Gonococcal Urethritis

a note
2. Writea note on Oncog ruses.
[Link] diagnosisofToxoplasmosis.
4. Write6 differencesbetween Streptococcuspneumonia and Streptococcusviridans.
5. Writea note on AtypicalMycobacteria.
6. Writea note on Aspergillosis.

I10=10
LAQAnv 1/2
)A23 year heterosexual male hlo dysuriaand noted some pus likedischarge lrom [Link] stainingfrom yellow pus
revealedpus cellswith intraceilularGram negativediplococcic..
What isthe etiologieal diagnosiswith reason(2M)
agent? Deseribe elinical
in detailsthe & ClinicalManifestationsof thisdisease (4)
Describe pathogenesis
Deseribe the detailsLaboratorydiagnosisof thisconditions(4)

ofSARS COVID-19 infection

pathogenesis (4)and Lab diagnosis
Mode of transmission. (4)
2) Describe Morphology (2).
 Departmentof Pharmacology
MGM MedicalCollege,Navi Mumbai
Id MBBS Preliminary Examination
Pharmacology
Subject:
TotalMarks: 100
Paper Duration:3 Hours
Date:12.12.22
SectionB

Q1)Answer any fiveoutofsixshortanswerquestion (5x630Marks)

1. Describevarioustypesof adversedrug reactionswithsuitable examples
[Link] a short note on "Plasma halflife ofa drug and itsclinical
significance
5. Describethe therapeuticuses of alpha blockers. between and aj selective
Differentiate and

non-selective
alpha blockers.
in [Link] the adverse
[Link] basisof use ofdigitalis congestive
effects
ofdigitalis
5. Describethemechanism of actíonand adverse effects [Link] are the advantages
ofLew MolecularWeight (LMW) heparinoverconventional heparin?
groups of drugs along withtheir
6. Enumerate the different rationaleused to treatacute

congestive glaucoma.

Q2) Answer any one out of two long answerquestions: (1x 1t=10Marks)
1. ClassifyB-adrenergic [Link]
uses,adverseeffects
and
contraindications.
A 42-yearanzemic woman with
2.
haemoglobin5 gm % was administeredInjIronDextran
IM. Subsequently the patientimmediatelycomplained dyspnoea,
of dizziness, palpitation
hypotension.
ldentifythe adverse drug reaction(ADR).
Write the drug therapy forthe management of
ADR
Writethe indicationsforparenteralirontherapy

SectionC

Q1)Answer any fiveoutofsixshortanswerquestions: (5x6 30

Marks)
1. Writethe merit and demerits of subcutaneous route of administration.
Add a note on
drug
new drug deliverysystems
2. Describethe varíousphases of reactionsgivingsuitable
biotransformation examples
3. Discuss the uses and adverse effects
of thiazide diuretics.
Write the rationalefor
combininghydrochlorochíazidewith Spironolactone
4 Describe the fourfundamental principles of Bioethics.
5. Write the mechanism of action of
aspirinas antiplatelet
agent. Writeuses ofantiplatelet
drugs.
6. Describe the therapeaticuses of
anticholinergic
agents.

.
Q2) Answcr any cne cutof two long2nswerquestions:
Classiíydrugs useG in peFtic
(1x10= Mzrks)
10
[Link] the mechanism ofactionof
[Link] a stnrtnote on Anti H. Pyloriagents and proton pump
regimens.
2 A 28-y ear 23rdnciwas
5rought to hospi:aiwith compiains of
vomitung, diarrhaea.
alriaiii, CC. and [Link]
sspnea. petrenu mas grosslyronfused. pulse razW
i i re engsiri:1ed tn examina:1 slie errehistory of
spraviagnsect es
 Departmentof Pharmacology
MGM Medical College,
NaviMumbai

2 MBBS
PreliminaryTheoryexamination
Subject:Pharmacology
Paper-2

SectionB
40 marks
1)ShortAnswerQuestions(SAQs)
Attempt5 outof6 5x 6 markseach = 30 marks
1. Enumerate the
therapeuticuses and adverse effects
of Opioids
2. Writeshort note on Non-sedative
anti-histaminies
3. Rationaleand benefits forcombining
sulphamethoxazole and trimethoprim
4. Enumerate the
therapeuticuses and adverse effects
of Benzodiazepines
5. Write short note on
"Informedconsent and consent refusal"
6. Enumerate the mechanism
ofactionand therapeuticusesofSalbutamol

2)Long AnswerQuestions(LAQS)Attempt1 outof2

ix10 marks = 10 marks
[Link]
systemicGlucocorticoids. Describe the mechanism
adverse effects
of ofaction, uses and
therapeutic
systemicGlucocorticoids.
2. An 18- yearold female
patientcame with the coplaints of feverand
days ago associated with headache. fatigue beginning 15
weakness, [Link] and
week [Link] patientwas pain diarrheaa
apathy. confused and discordantwas
Department of Infectious transferredtothe
Diseases. There was also
hypocalcemía, hypopotassemia.
pancytopenia, intestinal
hemorrhage, and hepatíc involvement. S. typhíwas
blood [Link] was grown in the
preseribed Flouroquínolonesfortyphoidcondition.
Describethe mechanism of actíon,
uses and adverse effects
therapeutiíc of Flouroquinolones.

SectionC

I
1)ShortAnswer Questions
(SAQs) Attempt5 outof6
Compare and contrastbetween typicai
2. Writethe mechanism of actíon and
3. Enumerate the
and atypical
adverse effects
antipyschotics
ofOralcombined
40 marks
5x 6 marks each =30

contraceptives
marks

mechanism of action,
therapeuticuses and adverseeffects
ofLignocaine
4 Enumerate the mechanism of
actíonand therapeuticuses
5. Writethe ofMctronidazole
6. Enumerate
management of statusepilepticus
mechanisn of action,
therapeuticuses and adverse effects
of
A
cabamazepiné
2) Long Answer Questions
(LAQs)Attempt1 out of2 x 10 marks = 10 marks
1. Classify
Oral Hypoglycemic
[Link] the mechanism ofaction,
adverse effects therapeuticuses and
ofMetformin
2. A 33-year-oldwoman
presented with a 1-month historyof
and weight loss. drycough,fever,
reducedappetite
She had taken
antitubercular
therapyabout a year with
prior partial
improvementin [Link] CT scan
image was suggestiveofa right
lesion. testwere upperlobemass
Microbiological forTuberculossis
positive and
ofmultidrug-resistanttuberculosis.
Genexpertreportssuggested
ClassifyAnti-tubercular
Describethe mechanism of action, drugs.
therapeuticuses and adverseeffects
ofIsoníazid.
note on Write
multidrug-resistant
tuberculosis.