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PERFORMANCE TASK 4
Grade Level/Learning Area Grade 10/ Science
Quarter/Week Third/Week 4
MELCs Explain how protein is made using information from
DNA
DNA RECIPE
(PROTEIN SYNTHESIS SIMULATION)
OVERVIEW:
Central Dogma of Molecular Biology: The process by which the information in genes flows into proteins:
DNA → RNA → protein
Protein synthesis is the process in which cells make proteins. Protein synthesis represents the major
route of disposal of amino acids. Amino acids are activated by binding to specific molecules of transfer
RNA and assembled by ribosomes into a sequence that has been specified by messenger RNA, which in turn
has been transcribed from the DNA template.
DIRECTION
DIRECTIONS:
1. Provide two colored pencils or pens of your choice.
2. Guided by the table below, fill in the data table labeled Gene A considering the following:
a. Take note of the sequence of nucleotides in DNA. On the lines provided in the data table, write the
appropriate sequence of nucleotides of mRNA that are complementary to the given DNA triplet
codes, and the sequence of tRNA nucleotides that are complementary to your given mRNA.
b. Fill in the blank after the amino acid sequence use a hyphen (-) to separate each amino acid number.
Record this information on the same data table.
c. Find out the answer for Trait, use figure 2. Find the trait that matches the amino acid sequence.
Record this information on the blank provided in the same data table for Gene A.
3. Repeat steps 2 a,b,c in filling all data tables in Figure 1 to 2 (Genes B,C,D,E, F).
4. Using all the inherited traits you gathered, make a sketch of how the fictitious organism FABDEC will
appear.
5. Use Figures 1 and 2 for reference.
Address: Rosario, Carmona, Cavite
Telephone Number: (046) 430-0108
2
Figure 1
mRNA triplet Amino Acid Number mRNA triplet Amino Acid Number
UAG 20 GGU 7
GAU 16 CGA 8
UGG 2 GCG 9
CCU 4 CCA 12
AUA 3 UCC 13
UGC 5 CCC 1
AAA 6 UUU 10
UCG 11 GCU 14
GGG 21
Figure 2
Amino Acid Sequence Trait Amino Acid Sequence Trait
2-7-4 Hairless 6-10 No Freckles
2-7-3 Hairy 6-9 Freckles
20-21-21 Plump 4-9-8 Blue Skin
13-14-15 Skinny 4-9-9 Orange Skin
11-14 Four- legged 20-20-16 Male
12-13-10-21 Long nose 20-20-14 Female
5-7-8-1 Short nose
6. Use this example as guide:
GENE X
DNA: ATC ATC CTA
mRNA: UAG UAG GAU
t RNA: AUC AUC CUA
Amino Acid Sequence: 20 - 20 - 16
Trait: Male
GENE A GENE D
DNA: ACC CCA TAT DNA: GGA CGC GCT
mRNA: ___________ mRNA: ____________
tRNA: ___________ tRNA: ____________
Amino Acid Sequence: _________ Amino Acid Sequence: ________
Trait: ____________ Trait:
Address: Rosario, Carmona, Cavite
Telephone Number: (046) 430-0108
2
GENE E GENE B
DNA: GGT AGG AAA CCC DNA: AGC CGA
mRNA: _________________ mRNA: __________
tRNA: __________________ tRNA: __________
Amino Acid Sequence: ___________ Amino Acid Sequence: _______
Trait: ____________ Trait: ________
GENE C GENE F
DNA: TTT CGC DNA: ATC ATC CGA
mRNA: _________________ mRNA: ____________
tRNA: __________________ tRNA: ____________
Amino Acid Sequence: ___________ Amino Acid Sequence: ________
Trait: ____________ Trait: ___________
NOTE: 1 POINT for each gene.
Make a sketch of your fictitious organism, FABDEC. Use all inherited traits recorded in your data
tables.
Guide Questions:
1. From this activity, what can you say about how proteins:
a. affect your genetic make-up?
b. create individual differences?
c. Become a very important constituent of your body?
Address: Rosario, Carmona, Cavite
Telephone Number: (046) 430-0108
2
RUBRICS FOR GUIDE QUESTIONS:
2 points - if the concept is accurate and the chosen idea is explained clearly and
precisely
1 point – if the concept is somewhat accurate and the chosen idea is explained clearly.
RUBRICS FOR FABDEC Fictitious Organism
4 points - if all inherited traits recorded in the data table presented are complete and
clear
3 points – most of the inherited traits recorded in the data table presented are
complete and clear
2 points - some of the inherited traits recorded in the data table presented are complete
and clear
1 point- only few of the inherited traits recorded in the data table presented are
complete and clear
Address: Rosario, Carmona, Cavite
Telephone Number: (046) 430-0108
