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trn:oi[Link]4520 5 Pages
Submission Date 392 Words
Mar 18, 2025, 12:30 AM GMT+5:30
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Mar 18, 2025, 12:31 AM GMT+5:30
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Application of Course [Link]
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Page 2 of 8 - Integrity Overview Submission ID trn:oi[Link]4520
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Page 3 of 8 - Integrity Overview Submission ID trn:oi[Link]4520
Page 4 of 8 - Integrity Submission Submission ID trn:oi[Link]4520
Application of Course Knowledge
Your Name
Name of your Institution
Name of the Course
Name of the Professor
March 16, 2025
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Application of Course Knowledge
Overview of the Study
Purpose:
In the US, between 50% and 80% of youngsters do not take their medications as
prescribed (Ralph et al., 2023). The study will establish if digital adherence monitoring and
motivational interviewing are superior to educational-based intervention in promoting
medication adherence among pediatric transplant recipients over six months.
Study Design:
The study utilizes a quantitative RCT design to allow the intervention and control groups
to be assessed equivalently based on objectified data.
Ethics Review:
The study was approved by an institutional review board (IRB) to ascertain compliance
with ethical requirements, that is, informed consent, confidentiality of the patients, and the safety
of the children participants.
Description of the Study
Research Question or Hypothesis:
The study postulates that e-adherence monitoring combined with motivational
interviewing will result in significantly higher levels of medication adherence than that produced
using traditional education-based strategies.
Study Aims:
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The study aims to quantify the improvement in adherence, determine adherence barriers,
and assess patient and caregiver participation in adherence programs.
Sampling Technique, Sample Size, and Characteristics:
A randomized sampling method was applied to allocate pediatric transplant patients to
intervention and control groups. The sample was 200 patients aged 5-18 on post-transplant
medication regimens.
Major Variables Studied
Independent Variable:
The intervention included digital adherence monitoring and motivational interviewing.
Dependent Variables:
Rates of medication adherence were assessed by electronic monitoring and self-report
adherence questionnaires.
Data Analysis and Statistics:
Statistical analysis was performed via t-tests and ANOVA in order to compare the groups'
adherence rates to each other. Statistical significance used p < 0.05.
Untoward Events:
There were no serious adverse events. There were minor technical difficulties with the
tracking system.
Application to Practice
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The research implies that electronic adherence monitoring with motivational interviewing
is effective in medication adherence. In practice, the strategy enhances patient outcomes, avoids
transplant rejection, and achieves long-term health. It may be within limited resources or patient
factors if relevant outcomes are not achieved.
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Reference
Ralph, J. E., Sezgin, E., Stanek, C. J., Landier, W., Pai, H., Gerhardt, C. A., & Skeens, M. A.
(2023). Improving medication adherence monitoring and clinical outcomes through
mHealth: A randomized controlled trial protocol in pediatric stem cell transplant. PloS
One, 18(8), e0289987–e0289987. [Link]
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