• VO2 – Ability to Deliver & Use Oxygen
• Oxygen uptake increases linearly until VO2max is
reached
• No further increase in VO2 with increasing work
rate
VO2max • Physiological factors influencing VO2max
• Ability of cardiorespiratory system to deliver
oxygen to muscles
• Ability of muscles to use oxygen and produce ATP
aerobically
Changes in Oxygen
Uptake With
Incremental Exercise
Unit –
Absolute – L/min
Relative – ml/kg/min
Calculation of VO2max
• Product of maximal cardiac output (Q) and arteriovenous
difference (a-vO2)
VO2max = HRmax x SVmax x (a-vO2)max
• Improvements in VO2max
• 50% due to SV
• 50% due to a-vO2
• Differences in VO2max in normal subjects
• Due to differences in SVmax
Stroke Volume and
Increased VO2max
• Increased SVmax
• Preload (EDV)
• Plasma volume
• Venous return
• Ventricular volume
• Afterload (TPR)
• Arterial constriction
• Maximal muscle blood flow with no
change in mean arterial pressure
• Contractility
Factors Increasing Stroke Volume
a-vO2 Difference and Increased VO2max
• Improved ability of the muscle to extract oxygen from the blood
• Muscle blood flow
• Capillary density
• Mitochondrial number
• Increased a-vO2 difference accounts for 50% of increased VO2max
Factors
Causing
Increased
VO2max
Training and VO2max
Training to increase VO2max Expected increases in VO2max Genetic predisposition
Large muscle groups, dynamic activity 15% (average) - 40% (strenuous or Accounts for 40%-66% VO2max
20-60 min, 3-5 times/week, 50-85% prolonged training)
VO2max Greater increase in highly deconditioned
or diseased subjects
Endurance training
HIIT
Altitude training
Heat training
Endurance Training Effects on Performance
Improved performance Structural and biochemical
following endurance training changes in muscle
Mitochondrial number
• Enzyme activity
Capillary density
Structural and Biochemical Adaptations to
Endurance Training
• Mitochondrial number
• Oxidative enzymes
• Krebs cycle (citrate synthase)
• Fatty acid (-oxidation) cycle
• Electron transport chain
• NADH shuttling system
• Change in type of LDH
• Adaptations quickly lost with detraining
Detraining and
VO2max
• Decrease in VO2max with
cessation of training
• SVmax
• maximal a-vO2 difference
• Opposite of training effect
About 50% of the increase in
mitochondrial content was lost after
one week of detraining
Detraining
Changes in All of the adaptations were lost after
Mitochondria five weeks of detraining
It took four weeks of retraining to
regain the adaptations lost in the
first week of detraining
Training/Detraining
Mitochondrial
Changes
VO2max (ml/kg/min)
Sports
Male Female
Kho Kho 48 - 51 32 – 64
Reference
Kabaddi 48 – 51 42 – 48
Values
Hockey 55 – 59 49 - 55
TT 53 – 56 41 – 44
Swimming 55 – 65 55 – 65
Taekwondo 55 – 60 50 – 54