End-of-life Care During the Last Days and Hours
Palliative Prognostic Score (PaP)
The PaP uses the Karnofsky Performance Score (KPS) and five other criteria to generate a numerical score from 0 to 17.5
to predict 30 day survival (higher scores predict shorter survival).
Performance status/Symptoms Partial score
Dyspnea
No 0
Yes 1
Anorexia
No 0
Yes 1
KPS
>50 0
30–40 0
10–20 2.5
Clinical Prediction of Survival
(weeks)
>12 0
11–12 2.0
9–10 2.5
7–8 2.5
5–6 4.5
APPENDICIES
3–4 6.0
1–2 8.5
102 REGISTERED NURSES’ ASSOCIATION OF ONTARIO
End-of-life Care During the Last Days and Hours
Performance status/Symptoms Partial score
Total WBC
Normal (4,800–8,500 cell/mm3) 0
High (8,501–11,000 cell/mm3) 0.5
Very high(>11,000 cell/mm3) 1.5
Lymphocyte percentage
Normal (20.0–40.0%) 0
Low (12.0–19.9%) 1.0
Very low (0–11.9%) 2.5
Risk groups Total score
A. 30-day survival probability >70% 0–5.5
B. 30-day survival probability 30–70% 5.6–11.0
C. 30-day survival probability <30% 11.1–17.5
PaP score = Dyspnea score + Anorexia score + KPS score + CPS score + Total WBC score + Lymphocyte percentage score.
Reprinted from Journal of Pain and Symptom Management, Vol. 17, No. 4, Maltoni, M, Nanni, O., Pirovano, M., Scarpi, E., Indelli, M.,
Martini, C., et al., Successful Validation of the Palliative Prognostic Score in Terminally Ill Cancer Patient, 240–247., Copyright (1999),
with permission from Elsevier.
Appendix E: Clinical Indicators of Decline
Diseases such as chronic obstructive pulmonary disease or congestive heart failure run a more fluctuating course and
result in death in a less predictable timeframe than diseases such as renal disease or dementia. Each exacerbation can lead to
remission (and future exacerbation) or death; knowing which will occur on any given admission is extremely challenging.
APPENDICIES
General indicators of poorer prognosis (life expectancy of only weeks to many weeks) include poor performance status,
impaired nutritional status and a low albumin level.
BEST PRACTICE GUIDELINES • [Link] 103