Tailored Therapies powered by Genomics and AI
CONCLUSION
The past decade has witnessed a rapid acceleration in our understanding of the genetic basis of
many diseases, which makes it possible to re-define diseases at a higher resolution and,
consequently, create more precise therapy. This is the goal of precision medicine, which has become
a term that symbolizes the most advanced modern and future medicine. For precision medicine to
work, two essential objectives need to be achieved. First, diseases need to be classified into various
subtypes. Second, targeted therapies must be available for each specific disease subtype. Disease
subtyping has evolved from pure clinical phenotyping to molecular subtyping and to finally a
comprehensive subtyping that combines molecular data from omics with clinical data from the
HER. Tailored treatment and preventative options for various disease subtypes have also greatly
expanded thanks to the contribution of targeted therapies, pharmaco-omics, and functional precision
medicine. To realize the full promise of precision medicine, a further integration of multiple levels
of information is needed. This includes the integration of information at the molecular level (i.e.,
genome, epigenome, proteome, metabolome), clinical and laboratory data, and environmental
factors. Big data analytics and artificial intelligence will be the key to accomplishing this
integration.
DEPT. OF CSE, MRIT, Mandya 2024-2025
Tailored Therapies powered by Genomics and AI
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DEPT. OF CSE, MRIT, Mandya 2024-2025
