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Important OBGYN Trials Cheat Sheet

The document outlines key obstetrics and gynecology trials relevant for postgraduate exams, highlighting significant findings such as the effectiveness of partographs in labor, the risks associated with hormone replacement therapy, and the outcomes of various surgical interventions. Trials like the AFFIRM, ARRIVE, and WHI have influenced clinical guidelines and practices in maternal and reproductive health. Additionally, it addresses infertility management through IVF embryo transfer guidelines and ovulation induction protocols.

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0% found this document useful (0 votes)
85 views1 page

Important OBGYN Trials Cheat Sheet

The document outlines key obstetrics and gynecology trials relevant for postgraduate exams, highlighting significant findings such as the effectiveness of partographs in labor, the risks associated with hormone replacement therapy, and the outcomes of various surgical interventions. Trials like the AFFIRM, ARRIVE, and WHI have influenced clinical guidelines and practices in maternal and reproductive health. Additionally, it addresses infertility management through IVF embryo transfer guidelines and ovulation induction protocols.

Uploaded by

khyatunp
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as PDF, TXT or read online on Scribd

Important Obstetrics and Gynecology Trials for Postgraduate Exams

Obstetrics Trials

WHO Partograph Trial Showed that using a partograph reduces prolonged labor and improves

maternal-fetal outcomes.

AFFIRM Trial Assessed fetal movement counting-did not significantly reduce stillbirths.

ARRIVE Trial Elective induction at 39 weeks in low-risk nulliparous women reduced cesarean

rates and hypertensive complications.

Hannah Breech Trial Planned C-section safer than vaginal delivery for term breech presentation.

PROBIT Trial Promotion of breastfeeding increased exclusive breastfeeding rates but no major

long-term health benefit was observed.

WHO Calcium Supplementation


Calcium
Trial reduces the risk of pre-eclampsia in women with low dietary calcium.

ASPIRIN Trial Low-dose aspirin reduces preterm birth and preeclampsia in nulliparous women.

MFMU Cesarean Registry Data source for outcomes related to trial of labor after cesarean (TOLAC).

Gynecology Trials

WHI Trial HRT increases risk of breast cancer, stroke, and heart disease-changed

guidelines for menopausal hormone therapy.

EVA Trial Hysteroscopic polypectomy vs blind curettage-hysteroscopy more effective.

LACC Trial Minimally invasive surgery for early-stage cervical cancer had worse outcomes

than open surgery.

UKCTOCS Trial Screening for ovarian cancer-multimodal screening reduced mortality, but not

significantly.

PEACH Trial Antibiotics as effective as surgery for mild PID.

ROCC Trial Routine cystoscopy reduced unrecognized ureteric injuries.

AUB Trials Helped standardize classification and evaluation of abnormal uterine bleeding

using PALM-COEIN.

Reproductive Medicine / Infertility Trials

HFEA & NICE Guidelines Determined number of embryos to transfer in IVF.

FASTT & FORTT Trials Evaluated cost-effectiveness and outcomes of ovulation induction protocols.

ESHRE Endometriosis Guidelines


Management strategies for infertility and pain in endometriosis.

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