Important Obstetrics and Gynecology Trials for Postgraduate Exams
Obstetrics Trials
WHO Partograph Trial Showed that using a partograph reduces prolonged labor and improves
maternal-fetal outcomes.
AFFIRM Trial Assessed fetal movement counting-did not significantly reduce stillbirths.
ARRIVE Trial Elective induction at 39 weeks in low-risk nulliparous women reduced cesarean
rates and hypertensive complications.
Hannah Breech Trial Planned C-section safer than vaginal delivery for term breech presentation.
PROBIT Trial Promotion of breastfeeding increased exclusive breastfeeding rates but no major
long-term health benefit was observed.
WHO Calcium Supplementation
Calcium
Trial reduces the risk of pre-eclampsia in women with low dietary calcium.
ASPIRIN Trial Low-dose aspirin reduces preterm birth and preeclampsia in nulliparous women.
MFMU Cesarean Registry Data source for outcomes related to trial of labor after cesarean (TOLAC).
Gynecology Trials
WHI Trial HRT increases risk of breast cancer, stroke, and heart disease-changed
guidelines for menopausal hormone therapy.
EVA Trial Hysteroscopic polypectomy vs blind curettage-hysteroscopy more effective.
LACC Trial Minimally invasive surgery for early-stage cervical cancer had worse outcomes
than open surgery.
UKCTOCS Trial Screening for ovarian cancer-multimodal screening reduced mortality, but not
significantly.
PEACH Trial Antibiotics as effective as surgery for mild PID.
ROCC Trial Routine cystoscopy reduced unrecognized ureteric injuries.
AUB Trials Helped standardize classification and evaluation of abnormal uterine bleeding
using PALM-COEIN.
Reproductive Medicine / Infertility Trials
HFEA & NICE Guidelines Determined number of embryos to transfer in IVF.
FASTT & FORTT Trials Evaluated cost-effectiveness and outcomes of ovulation induction protocols.
ESHRE Endometriosis Guidelines
Management strategies for infertility and pain in endometriosis.