Determine Erythrocyte Sedimentation Rate and
FP-009 RBCs
packed cell volume
Determination of blood group Blood
FP-010
Group
interpret Total Leucocyte Count,
FP-011 Differential Leucocyte Count (normal & abnormal) in a WBCs
CBC report generated by Automated Cell Counter.
MEDICAL BIOCHEMISTRY
Theory
Total Hours = 40
CODE SPECIFIC LEARNING OBJECTIVES DISCIPLINE TOPIC
Differentiate between different types of cells.
Explain the concept of organization of cells to
tissue, tissues to organ, organs to system. Structure of
FB-001
cell
Differentiate between the eukaryotic and
prokaryotic cells.
Describe the composition and structure of cell on
biochemical basis and justify it as fluid mosaic
model.
Describe the structure and function of cell Cell
FB-002
membrane with particular reference to the role of (i) Membrane
Lipids (ii) Carbohydrates (iii) Proteins Cell Biology
Explain why the cell membrane is called fluid
mosaic model
Discuss the various ways of cell-to-cell
communication and to the environment.
Describe cell to cell communications. Cell signaling Signal
FB-003
transduction
pathways (only G protein signaling)
Describe cell to cell adhesion.
Explain the biochemical markers and importance of
subcellular organelles and their inherited disorders Subcellular
FB-004
organelles
especially:
a. I- cell disease
b. Refsum disease
c. Parkinsonism
d. Progeria
Describe the chemistry of purines and pyrimidines
Chemistry of
FB-005 and their linkage in nucleic acid synthesis and their purine and
metabolism pyrimidines
Discuss the organization of DNA with special
reference to Watson and crick model, composition,
FB-006 structure, role of DNA
pairing and genetic coding
Describe the structural forms of DNA
Discuss the structure of different types of RNAs with
special reference to composition, linkage, functions
hn RNA, micro RNA
FB-007 Illustrate the structure and functions of various RNA
types of RNAs
Describe the functions of various small RNAs
present in cell
Explain the structure and nomenclature of
nucleotides, biomedical importance of natural and
synthetic analogues
FB-008 Interpret the role of synthetic analogues of Nucleotides
nucleotides in medicine based on sign/symptoms
and data e.g Methotrexate, 5 Flurouracil and
Allupurinol.
Explain the higher organization of DNA. Difference
FB-009 Chromosome
between DNA, chromatid and chromosome
Illustrate de Novo and salvage pathways of purines
and pyrimidines Nucleotide
FB-010
Describe the degradation of purine and pyramidine Metabolism
nucleotides
Interpret Lesch-Nyhan syndrome, gout and
adenosine deaminase deficiency on given data
Describe in detail all the steps in prokaryotic DNA
replication with emphasis on: Different proteins
required, Primers, DNA polymerase; their different
components and functions, Initiation, elongation
FB-011 Replication
and termination of replication, Topoisomerases
Describe in detail all the steps in Eukaryotic DNA
replication with emphasis on differences between
Pro- and Eukaryotes
Describe DNA repair especially Xeroderma
FB-012 DNA repair
pigmentosa
Explain the transcription in prokaryotes focusing on
Cell Biology
the following key points; RNA polymerase, its
components and functions, Initiation, elongation,
and termination of transcription
FB-013 Transcription
Illustrate the transcription in eukaryotes focusing on
the differences between pro- and eukaryotic
transcription and post transcriptional modifications
Wobble hypothesis
Interpret the translation focusing on the following
key points: Initiation, elongation and termination
FB-014 Translation
and inhibition by drugs
Describe Post-translational modification of proteins
Practical
BIOCHEMISTRY PRACTICAL Total Hours = 10
CODE
SPECIFIC LEARNING OBJECTIVES DISCIPLINE TOPIC
Demonstrate the step taken to prevent or rectify
FB-015 Lab hazards
the Laboratory Hazards Biochemistry
FB-016 Identify the structure of cells under microscope cell
