GRANULOMAS
DISEASES TYPES CLINICAL ETIOLOGY GROSS VIEW MICROSCO PICTURES
FEATURES PIC VIEW
Rhinosporidiosis [Link] • Polypoidal ➢ It is ▪ Large, soft, [Link]
rhinosporidiosis • Fleshy aquatic polypoidal mass squamous
[Link] • Reddish mass in protist with a reddish epithelium.
rhinosporidiosis nasal cavity related to appearance.
[Link] • Nasal Mesomyce ▪ Surface shows [Link] thick
rhinosporidiosis obstruction tozoea. white dots. walled
[Link] • Multiple ➢ Acquired ▪ Strawberry like sporangia of
rhinosporidiosis nodular lesion via contact surface. varying sizes in
• Conjuctival with the
growths stagnant subepitheloid.
water
especially
ponds,
lakes, or
river
baths.
Maduramycosis 1. Eumycetoma • Painless nodule ➢ Caused by ▪ Granules or ▪ Fungal
(mycetoma) (fungal) • Itching chronic grains visible hyphae
[Link] • Pus discharge granuloma in the in
a • Fever tous discharge. eumycet
(bacteria) • Dark color infection ▪ May be black, oma.
by either. white, yellow, ▪ Thin
➢ True or red filament
fungi, depending on ous in
Actinomyc causative Actinom
etes, organism. ycetoma.
Bacteria.
Leprosy [Link] • Nerve ➢ Caused by ▪ Dry, scaly, 1.(TL)Granulom
(Hansen’s [Link] thickening mycobacte anesthetic as with
Disease) 3. Mid-borderline • Multiple rium macules, or epitheloid cells,
4. Borederline symmetrical laprae, an plaques (TT). Langhans giant
lepromatous skin nodules acid-fast ▪ Multiple cells.
5. Lepromatous • Diffuse bacillus. nodules and
leprosy infiltration ➢ Transimitt plaques 2.(LL) Shows
6. Interminate • Leonine facies ed via diffuse foamy
leprosy • Weak immunity prolonged thickening of macrophages
skin or facial skin filled with
respiratory (LL). numerous
contact. ▪ Nerve bacilli.
enlargement.
Tuberculosis [Link] • Hemoptysis ➢ Inhalation ▪ Consolidation Caseating
[Link] • Chest Pain of ▪ Caseous granulomas,
[Link] TB • Fever Bacteria. Necrosis AFB,
[Link] • Weight Loss ▪ Fibrosis and lymphocytic
TB • Persistent ▪ Enlarged infiltrate
Cough lymph nodes
Actinomycosis [Link] Fever, weight loss, and most commonly Firm, painful Actinomyces
Actinomycosis malaise, Painful by swelling in the jaw colonies form
[Link] Swelling, Dental *Actinomyces or neck, Pleural yellowish
Actinomycosis Problems, Persistent israelii effusion, Pulmonary granules
[Link] cough , Chest pain or *Actinomyces Consolidation, Pelvic Filamentous
Actinomycosis Discomfort. gerencseriae Mass, chronic Bacteria: appear
[Link] *Actinomyces inflammation and as filamentous,
Actinomycosis naeslundii tissue destruction branching,
[Link] *Actinomyces Gram positive
Actinomycosis odontolyticus rods
Syphilis 1 .Primary • painless, firm, Treponema [Link] may • Bacteria
Syphilis and round ulcer, pallidum: A have skin rashes, Appear as
2 .Secondary site of infection, spiralshaped, blisters spiral-shaped
Syphilis usually on the Gramnegative [Link] organisms with
3 .Latent Syphilis genitals (penis, bacterium syphilis can cause a characteristic
4 .Tertiary vulva, vagina), that causes syphili skeletal corkscrew
Syphilis anus, or mouth deformities and motility
5 .Congenital • Swollen lymph hutchinson’s • darkfield
Syphilis nodes teeth microscopy
