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Ash Value Determination

The document discusses the determination of ash value in herbal drugs, which indicates the inorganic substances and potential adulteration present. It outlines two types of ash: physiological and non-physiological, and describes three methods for ash determination: total ash, acid insoluble ash, and water soluble ash. Each method involves incineration and specific calculations to assess the purity and identity of the drug.

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Gogul Ramnath
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977 views3 pages

Ash Value Determination

The document discusses the determination of ash value in herbal drugs, which indicates the inorganic substances and potential adulteration present. It outlines two types of ash: physiological and non-physiological, and describes three methods for ash determination: total ash, acid insoluble ash, and water soluble ash. Each method involves incineration and specific calculations to assess the purity and identity of the drug.

Uploaded by

Gogul Ramnath
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as PDF, TXT or read online on Scribd

Determination of Ash value in herbal drug

• It is the residue remaining after incineration that determines the inorganic


substances present in the drug. Similarly it can also detect the nature of the
material, which is added to the drug for the purpose of adulteration.

• Hence, determination of the ash value provides a criterion for judging the
identity and purity of the drug

• There are two types of ash one is the ash derived from plant tissues
(physiological ash) and the other one is residue of extraneous matter
adhering to plant surface (non-physiological ash)

• Ash is determined by following three methods

1. Total ash

• Weight of residue obtained after ignition.

• About 2gm of powdered drug was weighed

• Incinerated at 450°C in a muffle furnace


• It is cooled and weighed.

• Percentage of total ash was calculated with reference to air- dried substance.

• Determination of total ash value formula.

• total ash value of the sample = 100 (z-x) % /y.

• X= weight of empty dish.

• Y= weight of the drug taken.

• Z= weight of the dish + ash (after complete incineration)

2. Acid insoluble ash

• Weight of residue obtained after boiling the total ash with dilute hydrochloric
acid and igniting the remaining insoluble matter

• Ash obtained from the total ash was boiled with 25ml of 2N HCl for a few
minutes. Filtered through an ash less filter paper.

• The filter paper was transferred into a tarred silica crucible.

• Incinerated at 450°C in a muffle furnace


• It was cooled and weighed.

• Percentage of acid insoluble ash was calculated with reference to air-dried


substance

3. .Water soluble ash

• Difference in the weight between the total ash and the residue after
treatment of total ash with water the method is as follows

• Ash obtained from the total ash was boiled with ml of distilled water for a
few minutes and filtered through an ash less filter paper.

• The filter paper was transferred into a tarredsilica crucible.

• Incinerated at 450°C in a muffle furnace

• The crucible was cooled and weighed.

• Percentage of water-soluble ash was calculated with reference to air-dried


substance

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