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content (wont be on HoL1)
shew
LS7A lecture 8 notes (AoL 2 starts here)
Entertainment Pathways in the cell:
● cellular respiration: glucose is broken back down into carbon dioxide and water to generate usable energy (ATP)
● Photosynthesis: light energy drives trandformation of water and carbon dioxide into glucose
CotOTOTGCGHO-combustin
Cellular respiration: T
↑
water released as
heat
energy
● Energy transformation pathways help us recharge ATP to power cellular work
high free - energy
is
- CoHi200160a -6COn"6HzO +
686Kcalmal conserved
energyand -
Reactants : Products : You
mass free * In our bodies this
energy
,
6 C 6 C
12 H is conserved 12 I
free energy is used to
18 0
convert ADD + P: GATP
180
180 16 glad
.
b
180 .
169/mol
Conservation Laws Rules! energy mass speed of
● energy is neither created nor destroyed & & 6 light
● matter (mass) is neither created nor destroyed E =
mc"
Energy management molecules: NAD+/ NADH, FAD/FADH2
● these molecules lose and gain energy through redox reactions
● free energy is transferred to various “energy management” molecules
○ all free energy is released as heat
● Redox reactions: Oxidation Is Losing e- Reduction Is Gaining e- = OIL RIG
Oxidation ↓
GlinOo +
6On- >
6CO2"6H20+ energy reduced form= has more free
energy
higher
Shas more electrons)
Reduction -
> !
free energy
oxidizedreduced
● NAD+ to NADH is a endergonic process -> converting NAD+ to NADH requires 52.6 kcal/mol
● Highly reduced forms of carbon have high free energy
● The big picture: as the cell converts food molecules (glucose, fats, proteins) into CO2, free energy is released, transformed, &
used to make ATP from ADP + Pi
● the citric acid cycle completes the oxidation of glucose to CO2
● citric acid cycle: more energy is transferred to energy management molecules as Acetyl CoA is oxidized
● by the end of the citric acid cycle:
○ glucose is fully oxidized to CO2
○ free energy is stored in energy management molecules
● we convert sugar into CO2 through many small reactions in glycolysis and the Krebs cycle
● following the ciritric acid cycle but before ETC and oxidative phosphorylation, most of the available energy from the original
glucose molecule is found in NADH
● the production of ATP is endergonic on its own and is directly coupled to this exergonic process: the movement of protons
from high to low concentration.