Cell Cycle and Cell Division

Exercise - I
INTRODUCTION TO MODIFICATIONS 8. Gap between division phase and start of
OF MITOSIS DNA-replication is called :-
1. During G2 - phase a diploid cell contains the (1) G1 - phase (2) G2 - phase
amount of DNA equal to a :- (3) M - phase (4) Interkinesis
(1) Diploid cell (2) Tetraploid cell BCD008
(3) Haploid cell (4) Hexaploid cell 9. During cell division, spindle fibres attach to
BCD001 which part of chromosome ?
2. In which order, cytokinesis occurs in plants: (1) Primary constriction
(1) Centripetal (2) Centrifugal (2) Secondary constriction
(3) Oblique (4) Equatorial (3) Telomere
BCD002 (4) Satellite
3. Nuclear envelope reappears at :- BCD009
(1) Metaphase (2) Prophase 10. During which stage a diploid cell becomes
(3) Anaphase (4) Telophase tetraploid in mitosis?
BCD003 (1) G2 (2) Prophase
4. Which does not occurs in prophase ? (3) Metaphase (4) Anaphase
(1) Decondensation of chromatin BCD010
(2) Condensation of chromatin 11. Division of centromere occurs in:-
(3) Appearance of chromosome
(1) Prophase (2) Metaphase
(4) Disappearance of nuclear membrane and
(3) Anaphase (4) Telophase
nucleolus
BCD011
BCD004
12. What happens in synthesis phase during cell
5. In which stage of cell division, number of
cycle?
chromosomes can be best counted?
(1) DNA replication
(1) Prophase (2) Metaphase
(2) Chromosome number becomes double
(3) Telophase (4) Interphase
BCD005 (3) Formation of two nuclei
6. How many chromosomes shall be present in (4) Synthesis of tubulin proteins
a diploid cell at mitotic anaphase if ovum of BCD012
same species has ten chromosomes? 13. Reappearance of nucleolus along with
(1) 10 (Ten) (2) 20 (Twenty) thinning & elongation in chromosomes are
(3) 30 (Thirty) (4) 40 (Forty) diagnostic characters for the :-
BCD006 (1) Anaphase (2) Metaphase
7. In which stage of mitosis, the chromosomes (3) Interphase (4) Telophase
are composed of two chromatids ? BCD013
(1) Prophase & metaphase 14. Condensation of chromosomes and
(2) Anaphase and telophase appearance of astral rays occur during :-
(3) Prophase and telophase (1) Prophase (2) Metaphase
(4) Metaphase and anaphase (3) Anaphase (4) Telophase
BCD007 BCD014

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15. Chromosomal morphology (Structure) is best 23. Centromere is required for –
observed at :- (1) Movement of chromosomes towards
(1) Prophase (2) Metaphase poles
(3) Interphase (4) Anaphase (2) Cytoplasmic cleavage
BCD015 (3) Crossing over
16. M–phase of cell cycle consist of :– (4) Transcription
(1) G1, S and G2 phase BCD023
(2) Prophase, Metaphase, Anaphase, 24. At which stage of the cell cycle are histone
Telophase proteins synthesized in a eukaryotic cell ?
(3) Interphase, Prophase, Metaphase, (1) During telophase
(2) During S–phase
Anaphase, Telophase
(3) During G2–phase
(4) Only prophase
(4) During entire prophase
BCD016
BCD024
17. If the cell is diploid in G1 than after the S phase
25. Prophase which follows the S and G2 phases
cell remain/become :-
of interphase, is the first stage of :-
(1) n (2) 4n
(1) Meiosis-II (2) Karyokinesis
(3) 8n (4) 2n
(3) Interphase (4) G1 phase
BCD017
BCD025
18. Nuclear membrane disappears in :–
26. The two asters together with spindle fibres
(1) Late prophase (2) Early prophase
form:-
(3) Metaphase (4) Telophase
(1) Mitotic apparatus (2) Centromere
BCD018
(3) Astral fibres (4) Centrosome
19. Pre - DNA synthesis phase is:-
BCD026
(1) G1 - phase (2) G2 - phase
27. In prophase centrosome, which had
(3) S-phase (4) Prophase
undergone duplication during interphase,
BCD019
begins to move towards :
20. How many steps of division will occur in an
(1) Same pole of the cell
isolated tip cell to form 128 cells ?
(2) Opposite poles of the cell
(1) 128 (2) 127
(3) One towards centre while another towards
(3) 32 (4) 7
pole
BCD020
(4) Both towards centre
21. The number of chromatids in a chromosome at
BCD027
G2 state of cell cycle will be:-
(1) One (2) Two
MEIOSIS, SIGNIFICANCE OF MEIOSIS,
(3) Four (4) Eight
DIFFERENCES BETWEEN MITOSIS AND MEIOSIS
BCD021
22. Many cells function properly and divide 28. Which of the following not occurs in
mitotically even though they do not have :- Anaphase–I but occurs in Anaphase–II :–
(1) Plasma membrane (1) Condensation of chromosomes
(2) Cytoskeleton (2) Poleward movement of chromosomes
(3) Mitochondria (3) Shortening of spindle fibres
(4) Plastids (4) Splitting of centromere
BCD022 BCD028

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29. Crossing over takes place in :- 35. At anaphase - II of meiosis each chromosome
(1) Zygotene (2) Pachytene contains:-
(3) Diplotene (4) Diakinesis (1) 4 chromatids (2) 3 chromatids
BCD029 (3) 2 chromatids (4) 1 chromatid
30. Which of the two events maintain the BCD035
constant number of chromosomes across 36. In Anaphase – I each chromosome composed
generations? of:-
(1) Mitosis and Meiosis (1) One chromatid (2) Two chromatids
(2) Meiosis and fertilisation (3) Four chromatids (4) Many chromatids
(3) Fertilisation and mitosis BCD036
(4) Only meiosis 37. In meiosis, division of centromere occurs
BCD030 during:-
31. Match the column–I with column–II and (1) Interphase (2) Anaphase - I
select the correct answer :- (3) Anaphase - II (4) Metaphase - I
Column–I Column–II BCD037
(A) Pachytene (i) Bouquet stage 38. In meiosis, nuclear membrane and nucleolus
(B) Zygotene (ii) Chiasmata visible disappear during :-
(C) Diplotene (iii) Terminalisation (1) Zygotene (2) Pachytene
(D) Leptotene (iv) Gene exchange (3) Diakinesis (4) Metaphase - I
(E) Diakinesis (v) Synapsis BCD038
Options :- 39. Separation of homologous chromosomes
(1) A–i, B–ii, C–iii, D–iv, E–v during anaphase-I is called :-
(2) A–iv, B–v, C–ii, D–i, E–iii (1) Synapsis (2) Disjunction
(3) A–iii, B–iv, C–v, D–ii, E–i (3) Nondisjunction (4) Crossing over
(4) A–ii, B–iii, C–iv, D–i, E–v BCD039
BCD031 40. Diakinesis represents :-
32. Which part of plant is suitable for the study of (1) transition to prophase
meiosis? (2) transition to metaphase
(1) Root apex (2) Ovary (3) transition to anaphase
(3) Anther (4) Shoot apex (4) transition to telophase
BCD032 BCD040
33. Slipping of chiasmata towards the ends of 41. Synaptonemal complex is characteristic
bivalent is called :- of :-
(1) Terminalisation (1) Mitotic chromosomes
(2) Diakinesis (2) Leptotene chromosomes
(3) Interkinesis (3) Paired meiotic chromosomes
(4) Congression (4) Metaphase
BCD033 BCD041
34. "Bouquet-stage" occur in which sub stages of 42. Each chromosome composed of one
prophase-I ? chromatid in:-
(1) Leptotene (2) Zygotene (1) Anaphase – I (2) Anaphase – II
(3) Pachytene (4) Diplotene (3) Metaphase – I (4) Metaphase – II
BCD034 BCD042

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43. If the number of bivalents are 8 in 48. Which of the following is called heterotypic
metaphase–I, what shall be the number of division ?
chromosomes in daughter cells after (1) Meiosis–I (2) Meiosis–II
meiosis–I and meiosis–II respectively:- (3) Mitosis (4) Amitosis
(1) 8 and 4 (2) 4 and 4 BCD048
(3) 8 and 8 (4) 16 and 8 49. DNA replication occurs before :–
BCD043 (1) Mitosis and meiosis–I
44. Which of the following not occurs in (2) Mitosis, meiosis–I and meiosis–II
anaphase-I? (3) Meiosis-I only
(1) Segregation of homologous (4) Mitosis only
chromosomes BCD049
(2) Shortening in spindle fibres 50. Thick–thread stage is :–
(3) Poleward movement of chromosomes (1) Leptotene (2) Zygotene
(4) Division of centromere (3) Pachytene (4) Diplotene
BCD044 BCD050
45. In meiosis :-
51. Crossing over that results in genetic
(1) Division of nucleus twice but replication
recombination in higher organisms occurs
of DNA only once
between –
(2) Division of nucleus twice and replication
(1) Non-sister chromatids of a bivalent
of DNA twice
(2) Two daughter nuclei
(3) Division of nucleus once and replication
(3) Two different bivalents
of DNA is also once
(4) Sister chromatids of a bivalent
(4) Division of nucleus once and DNA
BCD051
replication is twice
52. When synapsis is complete all along the
BCD045
chromosome, the cell is said to have entered
46. After meiosis–I :-
a stage called :-
(1) the two chromatids of a chromosome are
(1) Zygotene (2) Pachytene
genetically similar
(3) Diplotene (4) Diakinesis
(2) the two chromatids of a chromosome are
BCD052
genetically different
53. If in a diploid plant cell the 'n' value is 16 then
(3) There occurs only one chromatid in each
what is possible in metaphase - I of meiosis ?
chromosome
(1) 32 Bivalents
(4) Four similar daughter cells are formed
(2) 64 Bivalents
BCD046
(3) 16 Bivalents
47. The correct sequence of prophase–I of
(4) 8 Bivalents
meiosis is :–
BCD053
(1) Leptotene, pachytene, zygotene, diplotene,
diakinesis 54. Which one of the following statements is
(2) Leptotene, diplotene, pachytene, zygotene, incorrect for interkinesis ?
diakinesis (1) It is the stage between the two subphases
(3) Leptotene, zygotene, pachytene, diplotene, (I & II) of a meiotic division
diakinesis (2) There is no replication of DNA
(4) Leptotene, zygotene, diakinesis, diplotene, (3) DNA replicate but chromosome number
pachytene remains same
BCD047 (4) It is generally short lived.
BCD054
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55. At anaphase-II, sister chromatids move 57. During gamete formation, the enzyme
towards opposite poles of the cell by : recombinase participates during :-
(1) Contraction in spindle fibre attached to (1) Prophase-I
kinetochores (2) Prophase-II
(2) Shortening of microtubules attached to (3) Metaphase-I
kinetochores (4) Anaphase-II
(3) Lengthening of microtubules attached to BCD062
kinetochores 58. Identify the meiotic stage in which the
(4) Relaxation in spindle fibre attached to homologous chromosomes separate while
kinetochores the sister chromatids remain associated at
BCD055 their centromeres :-
56. Synapsis occurs between :- (1) Anaphase I
(1) Two homologous chromosomes (2) Anaphase II
(2) A male and a female gamete (3) Metaphase I
(3) mRNA and ribosomes (4) Metaphase II
(4) Spindle fibres and centromere BCD064
BCD056

EXERCISE-I (Conceptual Questions) ANSWER KEY

Question 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
Answer 2 2 4 1 2 4 1 1 1 4 3 1 4 1 2
Question 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30
Answer 2 4 1 1 4 2 4 1 2 2 1 2 4 2 2
Question 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45
Answer 2 3 1 1 4 2 3 3 2 2 3 2 3 4 1
Question 46 47 48 49 50 51 52 53 54 55 56 57 58
Answer 2 3 1 1 3 1 2 3 3 2 1 1 1

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Exercise - II (Previous Year Questions) AIPMT/NEET

Understanding
AIPMT 2014 NEET-I 2016
1. During which phase(s) of cell cycle, amount of 6. Spindle fibres attach on to :-
DNA in a cell remains at 4C level if the initial (1) Telomere of the chromosome
amount is denoted as 2C ? (2) Kinetochore of the chromosome
(1) G0 and G1 (2) G1 and S (3) Centromere of the chromosome
(3) Only G2 (4) G2 and M (4) Kinetosome of the chromosome
BCD067 BCD072
2. In 'S' phase of the cell cycle :- 7. In meiosis crossing over is initiated at :
(1) Amount of DNA doubles in each cell. (1) Pachytene (2) Leptotene
(2) Amount of DNA remains same in each cell. (3) Zygotene (4) Diplotene
(3) Chromosome number is increased. BCD073
(4) Amount of DNA is reduced to half in each cell. NEET-II 2016
BCD068
8. During cell growth, DNA synthesis takes place
3. The enzyme recombinase is required at
in:-
which stage of meiosis :
(1) G2 phase (2) M phase
(1) Pachytene (2) Zygotene
(3) S phase (4) G1 phase
(3) Diplotene (4) Diakinesis
BCD074
BCD069
9. When cell has stalled DNA replication fork,
AIPMT 2015 which checkpoint should be predominantly
4. A somatic cell that has just completed the S activated?
phase of its cell cycle, as compared to gamete (1) M (2) Both G2/M and M
of the same species, has : (3) G1/S (4) G2/M
(1) same number of chromosomes but twice BCD075
the amount of DNA 10. Match the stages of meiosis in Column–I to
(2) twice the number of chromosomes and their characteristic features in Column–II
four times the amount of DNA and select the correct option using the codes
(3) four times the number of chromosomes given below :
and twice the amount of DNA Column-I Column-II
(4) twice the number of chromosomes and a Pachytene i
Pairing of homologous
twice the amount of DNA chromosomes
BCD070 b Metaphase-I ii Terminalization of
chiasmata
Re-AIPMT 2015 c Diakinesis iii Crossing over takes
place
5. Arrange the following events of meiosis in
d Zygotene iv Chromosomes align at
correct sequence : equatorial plate
(a) Crossing over
Codes :
(b) Synapsis
a b c d
(c) Terminalisation of chiasmata (1) ii iv iii i
(d) Disappearance of nucleolus (2) iv iii ii i
(1) (b), (c), (d), (a) (2) (b), (a), (d), (c) (3) iii iv ii i
(3) (b), (a), (c), (d) (4) (a), (b), (c), (d) (4) i iv ii iii
BCD071 BCD076

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Cell Cycle and Cell Division
NEET (UG) 2017 NEET (UG) 2019 (Odisha)
11. Which of the following options gives the 16. After meiosis-I, the resultant daughter cells have:
correct sequence of events during mitosis ? (1) Same amount of DNA as in the parent cell
(1) Condensation → nuclear membrane in S phase
disassembly → arrangement at equator (2) Twice the amount of DNA in comparison
→ centromere division → segregation to haploid gamete.
→ telophase (3) Same amount of DNA in comparison to
(2) Condensation→ crossing over → nuclear haploid gamete
membrane disassembly → segregation (4) Four times the amount of DNA in
→ telophase comparison to haploid gamete
BCD082
(3) Condensation → arrangement at
17. Crossing over takes place between which
equator→ centromere division
chromatids and in which stage of the cell cycle?
→ segregation → telophase (1) Non-sister chromatids of non-homologous
(4) Condensation → nuclear membrane chromosomes at Zygotene stage of
disassembly → crossing over prophase I.
→ segregation → telophase (2) Non-sister chromatids of homologous
BCD077 chromosomes at Pachytene stage of
12. Anaphase Promoting Complex (APC) is a prophase I.
protein degradation machinery necessary for (3) Non-sister chromatids of homologous
proper mitosis of animal cells. If APC is chromosomes at Zygotene stage of
defective in a human cell, which of the prophase I.
following is expected to occur ? (4) Non-sister chromatids of non-
(1) Chromosomes will be fragmented homologous chromosomes at Pachytene
(2) Chromosomes will not segregate stage of prophase I.
(3) Recombination of chromosome arms will BCD083
occur NEET (UG) 2020
(4) Chromosomes will not condense 18. Match the following with respect to meiosis:
BCD078 (a) Zygotene (i) Terminalization
NEET (UG) 2018 (b) Pachytene (ii) Chiasmata
13. The stage during which separation of the (c) Diplotene (iii) Crossing over
(d) Diakinesis (iv) Synapsis
paired homologous chromosomes begins is
Select the correct option from the following:
(1) Pachytene (2) Diplotene
(a) (b) (c) (d)
(3) Diakinesis (4) Zygotene
(1) (ii) (iv) (iii) (i)
BCD079 (2) (iii) (iv) (i) (ii)
NEET (UG) 2019 (3) (iv) (iii) (ii) (i)
14. The correct sequence of phases of cell cycle is: (4) (i) (ii) (iv) (iii)
BCD084
(1) M→ G1 → G2 → S (2) G1→ G2 → S → M
19. Identify the correct statement with regard to
(3) S→ G1 → G2 → M (4) G1→ S → G2 → M G1 phase (Gap 1) of interphase.
BCD080 (1) Nuclear Division takes place.
15. Cells in G0 phase:
(2) DNA synthesis or replication takes place.
(1) exit the cell cycle (3) Reorganisation of all cell components
(2) enter the cell cycle takes place.
(3) suspend the cell cycle (4) Cell is metabolically active, grows but
(4) terminate the cell cycle does not replicate its DNA.
BCD081 BCD085
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20. Some dividing cells exit the cell cycle and NEET (UG) 2021
enter vegetative inactive stage. This is called 26. Which of the following stages of meiosis
quiescent stage (G0). This process occurs at involves division of centromere ?
the end of : (1) Metaphase I (2) Metaphase II
(1) G2 phase (2) M phase (3) Anaphase II (4) Telophase II
(3) G1 phase (4) S phase BCD092
BCD086 27. Match List -I with List - II.
21. Dissolution of the synaptonemal complex List -I List -II
(a) S phase (i) Proteins are synthesized
occurs during :
(b) G2 phase (ii) Inactive phase
(1) Leptotene (2) Pachytene
(c) Quiescent (iii) Interval between mitosis
(3) Zygotene (4) Diplotene stage and initiation of DNA
BCD087 replication
(d) G1 phase (iv) DNA replication
NEET (UG) 2020 (Covid-19)
Choose the correct answer from the options
22. Attachment of spindle fibres to kinetochores given below.
of chromosomes becomes evident in : (a) (b) (c) (d)
(1) Anaphase (2) Telophase (1) (iii) (ii) (i) (iv)
(3) Prophase (4) Metaphase (2) (iv) (ii) (iii) (i)
BCD088 (3) (iv) (i) (ii) (iii)
23. In a mitotic cycle, the correct sequence of (4) (ii) (iv) (iii) (i)
phases is BCD093
(1) S, G1, G2, M (2) G1, S, G2, M 28. The fruit fly has 8 chromosomes (2n) in each
(3) M, G1, G2, S (4) G1, G2, S, M cell. During interphase of Mitosis if the
BCD089 number of chromosomes at G1 phase is 8,
what would be the number of chromosomes
24. During Meiosis-I, in which stage synapsis
after S-phase ?
takes place ?
(1) 8 (2) 16 (3) 4 (4) 32
(1) Pachytene (2) Zygotene
BCD094
(3) Diplotene (4) Leptotene 29. The centriole undergoes duplication during:
BCD090 (1) S-phase (2) Prophase
25. Match the following events that occur in their (3) Metaphase (4) G2 phase
respective phases of cell cycle and select the BCD095
correct option : 30. Which stage of meiotic prophase shows
Cell grows and organelle terminalisation of chiasmata as its distinctive
(a) G1 phase (i)
duplication feature?
DNA replication and (1) Leptotene (2) Zygotene
(b) S phase (ii) (3) Diakinesis (4) Pachytene
chromosome duplication
BCD096
(c) G2 phase (iii) Cytoplasmic growth NEET (UG) 2022
Metaphase Alignment of 31. The appearance of recombination nodules on
(d) (iv)
in M-phase chromosomes homologous chromosomes during meiosis
(1) (a)-(ii), (b)-(iii), (c)-(iv), (d)-(i) characterizes:
(2) (a)-(iii), (b)-(iv), (c)-(i), (d)-(ii) (1) Bivalent
(3) (a)-(iv), (b)-(i), (c)-(ii), (d)-(iii) (2) Sites at which crossing over occurs
(3) Terminalization
(4) (a)-(i), (b)-(ii), (c)-(iii), (d)-(iv)
(4) Synaptonemal complex
BCD091
BCD097
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32. Which one of the following never occurs 37. Identify the correct sequence of events
during mitotic cell division ? during Prophase I of meiosis :
(1) Movement of centrioles towards opposite (a) Synapsis of homologous chromosomes
poles (b) Chromosomes become gradually visible
(2) Pairing of homologous chromosomes under microscope
(3) Coiling and condensation of the (c) Crossing over between non-sister
chromatids chromatids of homologous chromosomes
(4) Spindle fibres attach to kinetochores of (d) Terminalisation of chiasmata
chromosomes (e) Dissolution of synaptonemal complex
BCD098 Choose the correct answer from the options
33. Select the incorrect statement with given below :
reference to mitosis: (1) (a), (b), (c), (d), (e)
(1) Spindle fibres attach to centromere of (2) (b), (c), (d), (e), (a)
chromosomes. (3) (b), (a), (c), (e), (d)
(2) Chromosomes decondense at telophase. (4) (a), (c), (d), (e), (b)
(3) Splitting of centromere occurs at BCD103
anaphase. 38. Bivalent or Tetrad formation is a
(4) All the chromosomes lie at the equator at characteristic feature observed during :
metaphase. (1) Synaptonemal complex in zygotene stage
BCD099 (2) Chiasmata in Diplotene stage
34. Regarding Meiosis, which of the statements is (3) Synaptonemal complex in Pachytene stage
incorrect ? (4) Chiasmata in zygotene stage
(1) DNA replication occurs in S phase of BCD104
Meiosis-II 39. With respect to metaphase, which of the
(2) Pairing of homologous chromosomes following statements is incorrect ?
and recombination occurs in Meiosis-I (1) Complete disintegration of nuclear
(3) Four haploid cells are formed at the end envelope takes place
of Meiosis-II (2) Chromosomes are highly condensed
(4) There are two stages in Meiosis, (3) Metaphase chromosomes are made up of
Meiosis-I and II four sister chromatids held together by
BCD100 centromere
(4) Chromosomes lie at the equator of the cell
Re-NEET (UG) 2022
BCD105
35. Which stage of meiosis can last for months or
NEET (UG) 2023
years in the oocytes of some verterbrates ?
(1) Leptotene (2) Pachytene 40. The process of appearance of recombination
(3) Diplotene (4) Diakinesis nodules occurs at which sub stage of
BCD101 prophase I in meiosis ?
36. In meiosis, crossing over and exchange of (1) Pachytene (2) Diplotene
genetic material between homologous (3) Diakinesis (4) Zygotene
chromosomes are catalyzed by the enzyme. BCD146
(1) Phosphorylase 41. Which of the following stages of meiosis
(2) Recombinase involves division of centromere ?
(3) Transferase (1) Metaphase II (2) Anaphase II
(4) Polymerase (3) Telophase (4) Metaphase I
BCD102 BCD147

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42. Among eukaryotes, replication of DNA takes NEET (UG) 2023 (Manipur)
place in - 45. The dissolution of synaptonemal complex
(1) S phase (2) G1 phase occurs during :
(3) G2 phase (4) M phase (1) Pachytene (2) Diplotene
BCD148 (3) Diakinesis (4) Leptotene
43. Match List I with List II: BCD151
List-I List-II 46. Doubling of the number of chromosomes can
(A) M Phase (I) Proteins are synthesized be achieved by disrupting mitotic cell division
soon after :
(B) G2 Phase (II) Inactive phase (1) Anaphase (2) Telophase
Interval between mitosis (3) Prophase (4) Metaphase
Quiescent
(C) (III) and initiation of DNA BCD152
stage
replication 47. During which stages of mitosis and meiosis,
(D) G1 Phase (IV) Equational division respectively does the centromere of each
chromosome split ?
Choose the correct answer from the options
(1) Mataphase, Metaphase II
given below:
(2) Prophase, Telophase I
(1) A-IV, B-II, C-I, D-III
(3) Telophase, Anaphase I
(2) A-IV, B-I, C-II, D-III
(4) Anaphase, Anaphase II
(3) A-II, B-IV, C-I, D-III
BCD153
(4) A-III, B-II, C-IV, D-I
BCD149 48. Which one of the following is the quiescent
stage of cell cycle ?
44. Select the correct statements.
(1) M (2) G2 (3) G1 (4) G0
A. Tetrad formation is seen during
BCD154
Leptotene.
B. During Anaphase, the centromeres split 49. Select correct sequence of substages of
and chromatids separate. Prophase-I of Meiotic division :
C. Terminalization takes place during (A) Zygotene (B) Pachytene
Pachytene. (C) Diakinesis (D) Leptotene
D. Nucleolus, Golgi complex and ER are (E) Diplotene
reformed during Telophase. Choose the correct answer from the options
E. Crossing over takes place between sister given below :
chromatids of homologous chromosome. (1) (D), (B), (A), (E), (C)
Choose the correct answer from the options (2) (A), (B), (D), (E), (C)
given below: (3) (D), (A), (B), (E), (C)
(1) B and D only (2) A, C and E only (4) (A), (D), (B), (C), (E)
BCD155
(3) B and E only (4) A and C only
BCD150

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Cell Cycle and Cell Division

EXERCISE-II (Previous Year Questions) ANSWER KEY

Question 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
Answer 4 1 1 2 3 2 1 3 4 3 1 2 2 4 3
Question 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30
Answer 2 2 3 4 3 4 4 2 2 4 3 3 1 1 3
Question 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45
Answer 2 2 1 1 3 2 3 1 3 1 2 1 2 1 2
Question 46 47 48 49
Answer 4 4 4 3

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 NEET : Biology

Exercise - III Master Your Understanding

EXERCISE-III(A) NCERT BASED QUESTIONS 4. Prophase–I of meiotic division is typically
1. Which one is correct for G0 stage ? longer and more complex, it is subdivided
into five phases, on the basis of :-
I. It is a quiescent stage.
(1) Staining
II. In this phase cell cycle is stopped (2) Behaviour of chromosomes
III. G0 cells do not proliferate but metabolically (3) Duration
active (4) Number of chromosomes
IV. G0 cells can divide in response to some BCD109
5. Arrange the following events of meiosis in the
stimulus
correct sequence -
Options :- A. Terminalisation of chiasmata
(1) All are correct B. Crossing over
(2) Only I, II, III are correct C. Synapsis
(3) Only I, II are correct D. Disjunction of chromosomes
(4) Only I and IV are correct E. Dissolution of synaptonemal complex
BCD106 The correct sequence is-
(1) A → B → C → D → E
2. Which of the following is not correctly
(2) E → D → C → B → A
matches a phase of the cell cycle with its
(3) C → B → D → E → A
function ?
(4) C → B → E → A → D
(1) Second Period of cytoplasmic BCD110
gap phase growth 6. Identify the following diagram-
(2) First Most of the organelle
gap phase duplication
(3) Interphase Phase of preparation
for cell division
(4) DNA synthesis Doubling of number
phase of chromosomes
in cell
(1) Transition to Metaphase
BCD107 (2) Transition to Anaphase-II
3. Mark incorrect statements :- (3) Transition to Metaphase-I
(A) Meiosis involves only a single cycle of (4) Transition to Anaphase
DNA replication BCD111
(B) Four haploid cells are formed at the end 7. The drawing below shows a cell whose
of meiosis–I diploid chromosome number
is four. This cell is in:-
(C) Meiosis occurs in diploid cells
(D) In yeast, cell cycle takes about 90 minutes. (1) Metaphase of mitosis
Options :- (2) Anaphase of mitosis
(1) A and B (2) A and C (3) First anaphase of meiosis
(3) Only B (4) All are correct (4) Second anaphase of meiosis
BCD108 BCD112

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Cell Cycle and Cell Division
8. Label the structures indicated by (i), (ii), (iii) 13. Regarding to cell cycle which of the following
and (iv) in below given diagram – statements is wrong ?
(1) Cytoplasm increase is a continuous process
(2) DNA synthesis occurs only during one
(ii)
specific stage
(i) (3) Replicated chromosomes distributed to
(iv) daughter nuclei by complex series of
events
(4) Events for replicated chromosomes
(iii) distribution are not under genetic control
BCD118
(1) (i)-Chromatid, (ii)-Centriole, 14. About cell cycle, which of the following
(iii)-Centromere, (iv)-Chromosome statements is correct ?
(2) (i)-Chromosome, (ii)-Centriole, (1) In G0 phase cells are metabolically inactive
(iii)-Centromere, (iv)-Chromatid (2) In G0 phase cells are metabolically active
(3) Diploid somatic cells of animals divide
(3) (i)-Chromatid, (ii)-Centromere,
only by meiotic division
(iii)-Centriole, (iv)-Chromosome
(4) In plants only haploid cells can show
(4) (i)-Chromosome, (ii)-Centromere, mitotic divisions
(iii) Centriole, (iv)-Chromatid BCD119
BCD113 15. Chromatin condensation and movement of
9. Interkinesis is stage between :- duplicated centrioles towards opposite poles
(1) Two mitotic divisions can be observed during-
(1) Prophase (2) Metaphase
(2) Two phases of meiotic divisions
(3) Anaphase (4) Telophase
(3) Anaphase and telophase
BCD120
(4) Leptotene and zygotene 16. Regarding arrangement of chromosomes on
BCD114 equator during metaphase, which of the
10. It is significant to note that in the 24 hour following statements is incorrect ?
(1) Each chromatid remains connected by
average duration of cell cycle of human cell,
one spindle fibres from both poles
cell division proper lasts for only about:- (2) Each chromosome remains connected by
(1) Four hours (2) 90 minutes spindle fibres from both poles
(3) An hour (4) 10 hours (3) Spindle fibres remain attached on
BCD115 kinetochores of both the chromatids
11. In which stage of mitotic division, cells do not (4) Each chromatid remains connected at one
show Golgi complex, ER, nucleolus and pole by spindle fibres
BCD121
nuclear envelope ?
17. Match the following -
(1) Metaphase (2) Late prophase (a) Prophase (I) Decondensation
(3) Anaphase (4) All of these of chromosome
BCD116 (b) Metaphase (II) Division of centromere
(c) Anaphase (III) Attachment of
12. Condensation of chromosomes is completed in:-
spindle fibres on
(1) Prophase (2) Interphase kinetochores of
(3) Metaphase (4) Anaphase chromosomes
(d) Telophase (IV) Initiation of assembly
BCD117
of mitotic spindle

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 NEET : Biology
Options :- 22. A cell has 46 chromosomes at each pole in
(1) a–(IV) b–(III) c–(I) d–(II) mitotic telophase. In this division the number
(2) a–(IV) b–(III) c–(II) d–(I) of chromatids at the metaphase was :-
(3) a–(III) b–(IV) c–(II) d–(I)
(1) 23 (2) 46 (3) 92 (4) 69
(4) a–(III) b–(IV) c–(I) d–(II)
BCD127
BCD122
18. Which of the following is not a significance of 23. Match the following -
mitosis ? (a) Prophase-II (I) Enclosure of
(1) Maintenance of identical genetic chromosomes in
complement nuclear envelope
(2) Cell repair (b) Metaphase-II (II) Separation of
(3) Restore nucleo cytoplasmic ratio sister chromatids
(4) Genetic variability
(c) Anaphase-II (III) Chromosome
BCD123
alignment on
19. Meiosis ensures the production of ...........
phase in life cycle of sexually reproducing equator
organism, where as fertilisation restores ......... (d) Telophase-II (IV) Disappearance of
phase. nuclear membrane
(1) diploid, haploid (2) haploid, triploid Options :-
(3) diploid, triploid (4) haploid, diploid (1) a–(IV) b –(III) c–(I) d–(II)
BCD124 (2) a–(IV) b–(III) c–(II) d–(I)
20. Regarding key features of meiosis select out
(3) a–(IV) b–(II) c–(III) d–(I)
the wrong one -
(4) a–(IV) b–(I) c–(II) d–(III)
(1) Meiosis involves two sequential cycles of
nuclear and cell division called meiosis- I BCD128
& meiosis- II 24. Which of the following is not a significance of
(2) Meiosis is initiated after the parental meiosis ?
chromosomes have replicated to produce (1) Helps in conservation of specific
identical sister chromatids at the S - Phase chromosome number in each species
(3) Meiosis involves pairing of homologous
(2) Increase in genetic variability
chromosomes and recombination
(3) Helps in evolution
between non homologous chromosome
(4) Four haploid cells are formed at the end of (4) Helps in growth of organism
meiosis-II BCD129
BCD125 25. Number of chromatids in each chromosome
21. Select the odd one - at anaphase is-
(1) Zygotene – Synaptonemal
(1) One in mitosis, one in meiosis-I and two in
complex appearance
meiosis-II
(2) Pachytene – Appearance of
recombination (2) One in mitosis, two in meiosis-I and one in
nodule meiosis-II
(3) Diplotene – Terminalisation (3) Two in mitosis, one in meiosis-I and two
of chiasmata in meiosis-II
(4) Diakinesis – Assembly of (4) Two in mitosis, two in meiosis-I and two
meiotic spindle in meiosis-II BCD130
BCD126
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Cell Cycle and Cell Division
26. During meiosis how many cycles of nucleus 32. A mouse cell is treated with a chemical that
division, DNA replication and division of interferes with the activity of actin protein.
centromere take place respectively ? Which of the following will probably be
(1) Three, Two, One (2) One, Two, Two affected the most?
(3) Two, Two, One (4) Two, One, One (1) Formation of spindle fibres
(2) Division of cytoplasm
BCD131
(3) Chromosome duplication
27. Cell cycle includes :-
(4) Pairing of homologous chromosomes
(1) Cell division (2) DNA replication BCD137
(3) Cell growth (4) All of the above 33. Number of chromosome pairs at equator
BCD132 in metaphase-I of a diploid plant cell
28. Interphase of an animal cell is differ from (for which n = 25) shall be-
interphase of a plant cell :- (1) 50 (2) 100 (3) 75 (4) 25
(1) in having DNA replication BCD138
(2) in having centrioles duplication 34. In a diploid cell before S-phase if quantity of
(3) in having growth of cell DNA is 20 pico gram (pg) then after meiosis I
what will be the quantity of DNA in each
(4) in having metabolically active cell
daughter cell ?
BCD133
(1) 10 pg (2) 20 pg (3) 5 pg (4) 40 pg
29. Multinucleated condition in the liquid BCD139
endosperm of coconut arises because :- 35. Diploid cell in human, where cell division
(1) DNA replication not occurs during cell does not occur :-
cycle (a) Heart cell (b) Muscle cell
(2) Separation of sister chromatids not (c) Nerve cell
occurs in anaphase Options :-
(3) Condensation of chromosomal material (1) Only c (2) b and c
not occurs in prophase (3) a and c (4) a, b and c
(4) Karyokinesis is not followed by BCD140
36. Given below are two statement -
cytokinesis
Statement-I : M-phase is the most dramatic
BCD134 phase of cell cycle, involving a major
30. Which of the following phases can last for reorganisation of virtually all component of
months or years in oocytes of some cell.
vertebrates ? Statement-II : Cells in G0-stage remain
(1) Leptotene (2) Zygotene metabolically inactive but no longer
(3) Pachytene (4) Diplotene proliferate unless called on to do so
BCD135 depending on the requirement of the
organism.
EXERCISE-III(B) ANALYTICAL QUESTIONS In the light of the above statements, choose
31. Which of the following organelles can be the correct answer from the options given below
observed in a cell even after completion of (1) Both statement I and statement II are
correct
prophase?
(2) Both statement I and statement II are
(1) Golgi complex
incorrect
(2) Mitochondria (3) Statement I is correct but statement II is
(3) Nucleus incorrect
(4) Endoplasmic reticulum (4) Statement I is incorrect but statement II is
BCD136 correct BCD141
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 NEET : Biology
37. Assertion (A) : Meiosis ensures the 40. What will be the ratio of number of
production of haploid phase in the life cycle of chromosomes and amount of DNA in G1, S and
sexually reproducing organism. G2 phases for a somatic cell?
Reason (R) : Meiosis involve reduction in G1 S G2
chromosome number to half as that of parent (1) 1 : 1 1:I 1:1
cell. (2) 1 : 1 1:2 I:2
(1) Both Assertion and Reason are True and (3) 1 : 2 1:2 I:2
the Reason is a correct explanation of the (4) 1 : 2 1:1 1:2
Assertion. BCD145
(2) Both Assertion and Reason are True but 41. Given below is a schematic break-up of the
Reason is not a correct explanation of the phases/stages of cell cycle :-
Assertion. A
(3) Assertion is True but the Reason is False. B C
(4) Both Assertion and Reason are False. Mitosis
BCD142 Inter-
38. Assertion (A) : Cytokinesis in plant cell occur phase
D
by cell plate formation method.
Reason (R) : Cytokinesis in animal cells occur Which one of the following is the correct
by the formation of cell farrow. indication of the stage/phase in the cell cycle?
(1) Both Assertion and Reason are True and (1) A – Cytokinesis
the Reason is a correct explanation of the (2) B – Metaphase
Assertion. (3) C – Karyokinesis
(2) Both Assertion and Reason are True but (4) D – Synthetic phase
Reason is not a correct explanation of the BCD057
Assertion. 42. During mitosis ER and nucleolus begin to
(3) Assertion is True but the Reason is False. disappear at :
(4) Both Assertion and Reason are False. (1) Early prophase (2) Late prophase
BCD143 (3) Early metaphase (4) Late metaphase
39. Assertion (A) : No replication of DNA is BCD058
needed between meiosis-I and meiosis-II. 43. Which stages of cell division do the following
Reason (R) : Chromosomes are already figures A and B represent respectively ?
duplicated and they already have two sister
chromatids.
(A) (B)
(1) Both (A) and (R) are correct but (R) is not
the correct explanation of (A).
(2) (A) is correct but (R) is not correct.
(1) Prophase – Anaphase
(3) (A) is incorrect but (R) is correct.
(2) Metaphase – Telophase
(4) Both (A) and (R) are correct but (R) is the
(3) Telophase – Metaphase
correct explanation of (A).
(4) Late Anaphase – Prophase
BCD144
BCD059

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Cell Cycle and Cell Division
44. Select the correct option with respect to (1) Prophase of Mitosis
mitosis (2) Both prophase and metaphase of mitosis
(1) Chromatids separate but remain in the (3) Prophase I during meiosis
centre of the cell in anaphase. (4) Prophase II during meiosis
(2) Chromatids start moving towards BCD063
opposite poles in telophase. 47. A stage in cell division is
(3) Golgi complex and endoplasmic reticulum shown in the figure. Select the
are still visible at the end of prophase. answer which gives correct
(4) Chromosomes move to the spindle identification of the stage with
equator and get aligned along equatorial its characteristics.
plate in metaphase
BCD060
Endoplasmic reticulum and
45. At metaphase, chromosomes are attached to (1) Telophase
nucleolus not reformed yet.
the spindle fibres by their :-
(1) Centromere Nuclear envelop reforms,
(2) Telophase
(2) Satellites Golgi complex reforms.
(3) Secondary constrictions Chromosomes move
(4) Kinetochores Late
(3) away from equatorial plate,
BCD061 anaphase
Golgi complex not present.
46. Given below is the representation of a certain Cell plate formed,
event at a particular stage of a type of cell (4) Cytokinesis mitochondria distributed
division. Which is this stage ? between two daughter cells.

BCD065

Exercise - III ANSWER KEY

Question 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
Answer 1 4 3 2 4 1 3 1 2 3 4 3 4 2 1
Question 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30
Answer 1 2 4 4 3 3 3 2 4 2 4 4 2 4 4
Question 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45
Answer 2 2 4 2 4 3 1 2 4 2 4 2 4 4 4
Question 46 47
Answer 3 2

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 NEET : Biology

Important Notes

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