HOTS Problem Bank – Monohybrid Cross (Class 10, Very Difficult)
1. Cross a pure tall pea plant (TT) with a dwarf plant (tt). Show F₁ and F₂ generations with
ratios.
2. Cross a heterozygous tall (Tt) with a dwarf (tt). Show genotypic and phenotypic ratios.
3. Cross two heterozygous round seeds (Rr × Rr). Write F₂ ratios.
4. A heterozygous yellow seed (Yy) is crossed with a homozygous green (yy). Predict
outcomes.
5. A purple flower (Pp) is selfed. What is the probability of obtaining homozygous purple in
the progeny?
6. From an F₂ tall plant, how can you confirm whether it is TT or Tt? Design a test cross.
7. Black fur (B) is dominant over white (b). Cross a heterozygous black (Bb) with a white
rabbit. Show results.
8. Two black rabbits produced 18 black and 6 white offspring. Deduce genotypes of parents.
9. A black rabbit of unknown genotype is test-crossed with white. Offspring: 50% black,
50% white. Find parent genotype.
10. A homozygous black rabbit crossed with heterozygous black. Show genotypic ratios.
11. In a litter of 200 rabbits from Bb × Bb cross, how many are expected to be white?
12. Black coat (B) dominant over white (b). Cross two heterozygous black guinea pigs. Out
of 64 offspring, calculate expected numbers of BB, Bb, and bb.
13. A homozygous black guinea pig is crossed with a white one. Show F₁ and F₂ generations.
14. Rough coat (R) dominant over smooth (r). Cross heterozygous rough × heterozygous
rough. Show ratio.
15. A rough-coated guinea pig crossed with smooth produced 50% rough and 50% smooth.
Deduce the genotype of rough parent.
16. Widow’s peak (W) dominant over no widow’s peak (w). A heterozygous man marries a
ww woman. Show expected outcomes.
17. Free earlobe (E) dominant over attached (e). Cross Ee × Ee. What is the probability of
attached lobes in 3 children born in a row?
18. Dimple chin (D) dominant over no dimple (d). Cross DD × Dd. Give phenotype ratio.
19. Tongue rolling (R) dominant over inability (r). Cross heterozygous roller with a non-
roller. Find probability of roller offspring.
20. If both parents are heterozygous for free earlobes, out of 160 children, how many are
expected to have attached earlobes?
21. A man with blood group A (IAi) marries a woman with blood group B (IBi). List all
possible blood groups of their children.
22. A father has blood group AB (IAIB) and mother has O (ii). Predict offspring blood
groups.
23. A child has O blood group. Father has blood group A, mother has blood group B. Deduce
possible genotypes of both parents.
24. A man with blood group A (IAIA) marries a woman with O (ii). Predict all offspring
blood groups.
25. In a marriage between IAi and IAIB, calculate probability of AB blood group child.
26. In snapdragons, red (RR) × white (WW) = pink (RW). Cross RW × RW. Give phenotypic
and genotypic ratios.
27. Cross pink (RW) × white (WW). Show expected ratios.
28. Cross red (RR) × pink (RW). Show phenotypes of offspring.
29. In RW × RW, if 128 plants are grown, how many will be red, pink, and white?
30. A gardener crosses 2 pink snapdragons and grows 300 offspring. Predict expected
numbers of each phenotype.
