Acne, Rosacea and Related Disorder
1. Acne
2. Perioral Dermatitis
3. Rosacea
4. Hidradenitis suppurativa
5. Sweat Glands Disorder
• Miliaria crystallina
• Miliaria rubra
• Miliaria profunda
Sweat pore is closed due to heat exposure
Obstruction of eccrine ducts
Retention of sweat then ductal ruptures
Leaking sweat to surrounding tissue
Miliaria crystallina
Miliaria rubra
Miliaria profunda
Premalignant Skin Tumors
1. Actinic Keratosis
2. Marjolin’s ulcer
3. Bowen’s disease
4. Erythroplasia of Queyrat
5. Leukoplakia
6. Arsenic keratosis
7. Paget’s disease
A clinical term that reverse to a predominantly
white lesion of the oral mucosa that cannot be
rubbed of or characterized by any other
definable lesion or known disease
OL SCC
Up to 20% in 1-30 years
Exceed 1% annually
Related Risk Factors
• Tobacco product
• Concomitant alcohol use
• History of previous OSCC
• History of other premalignant lesions
• Infection with certain HPV sub types
• Candidiasis
TREATMENT
1. Regress/clear spontaneously
• after stopping risk factors
2. 1% 5 FU solutions bid
• combined with lidocaine gel
3. Surgery
• cryosurgery
• electro surgery
• excision
• CO2 laser
PUSTULAR ERUPTIONS OF
THE PALMS AND SOLES
1. Pustulosis Palmaris et Plantaris (PPP)
2. Acrodermatitis Continua (Hallopeau)
3. Infantile Acropustulosis
CHARACTERISTICS
1. Chronic pustular dermatoses of unknown origin
2. Sterile pustules, limited to palms and soles
3. Intraepidermal vesicles with massive neutrophil
exositosis
4. 20-60 y/o with F:M = 3:1
5. Recalcitrant to treatment
6. Decreased anti leukoprotease activity
7. Triggering factors:
Smoking, Thyroid’s disease, Anxiety
Helicobacter pylori infections
PPP could be a part of other diseases:
SAPHO disease
(Synovitis, Pustulosis, Hyperostosis, Osteitis)
Osteoarthritis of anterior muscle of the heart
Chronic recurrent multifocal osteomyelitis
Generalized Pustular Psoriasis (GPP)
Intraepidermal cleft
Neutrophil exositosis
Laboratory Findings:
Moderate increased of WBC
Increased level of CRP
Increased level of serum anti-gliadin
antibody
DIFFERENTIAL DIAGNOSIS:
2nd Infected pompholyx
Tinea manuum
Scabies
Jarang
Vesicopustular type mycosis fungoides
Localizedpustular vasculitis
Palmoplantar pustulosis in GPP
TREATMENT
Topical Physics Systemics
1st line Poten/superpoten CS Psoralen - Acitretin 0,5
Calcipotriol PUVA mg/kgbb/hari
2nd line - Anthralin - Methotrexate
- Tazarotene - Cyclosporin
- Fumaric acid
esters
3rd line - Efalizumab
