Calcium

Babar Asad Bareera Farhan

M Hassaan Ansari Mahnoor Majeed
Abdul Hannan Sandhiya Punshi
Muhammad Hassan Shehzeen
Turoob Arab Farooqui Syeda Aamna Wasti
 Objectives

• Effects Of Calcium In Body

• I/V & Oral Calcium Preparations

• Side Effects of Calcium Therapy

• Food/Diet Rich in Calcium

 Effects Of Calcium In Body
Calcium is also a coagulation The sarcomeres of Calcium is essential for building Calcium also plays a key role in
factor (factor IV). In extrinsic muscles rely on calcium and maintaining healthy bones nerve impulse transmission.
pathway, along with factor VIIa, it for contraction. throughout life. Calcium Upon entering a presynaptic
binds to release tissue factor to Attachment of calcium to combines with other minerals to terminal, an action potential
activate factor X. Similarly in the troponin frees the myosin form hard crystals
10 of Ca (PO )
4 3
opens Ca2+ channels, and
intrinsic pathway, calcium and binding sites on actin transiently increases the local
(OH) giving bones strength and
factor XIa activate factor IX. Then filament, thus allowing Calcium concentration at the
structure. Almost 99% of the
along with factors IXa and VIIIa, it myosin to attach to the presynaptic active zone. Ca2+
body’s calcium is found in the triggers synaptic vesicle fusion
activates factor X. Likewise its also actin and produce
bones. and neurotransmitter exocytosis
important in the common pathway contraction
in a few hundred microseconds,
possibly less.
In cardiac cells, calcium is
essential for a longer-lasting
action potential, which is
formed by the slower calcium-
sodium gates
I/V & Oral Calcium
Preparations
I/V Preparations Oral Preparations
Several different kinds of calcium compounds are
Calcium gluconate is a calcium salt used to directly used in calcium supplements. Each compound
replete serum calcium levels in cases of contains varying amounts of calcium — referred to
hypocalcemia through IV administration. as elemental calcium. Common calcium
Hypocalcemia occurs in 15% to 88% of hospitalized supplements may be labeled as:
adult patients, depending on the measurement
method (serum or ionized calcium). ·Calcium carbonate (40% elemental calcium)
·Calcium citrate (21% elemental calcium)
Calcium gluconate is the calcium salt of gluconic
·Calcium gluconate (9% elemental calcium)
acid. Gluconic acid is an oxidation product of
·Calcium lactate (13% elemental calcium)
glucose. There is 93 mg of elemental calcium in a 10
The two main forms of calcium supplements are
mL ampule of 10% calcium gluconate. In carbonate and citrate. Calcium carbonate is
comparison, there is 272 mg of elemental calcium in cheapest and therefore often a good first choice.
10 mL of 10% solution of calcium chloride, another Other forms of calcium in supplements include
calcium salt. Calcium gluconate is typically preferred gluconate and lactate
 Side Effects Of Calcium
Therapy
1) Digestive Issues: Constipation, 3) Cardiovascular Issues: High
bloating, gas, and nausea. doses of calcium, especially when
combined with vitamin D, may
2) Kidney Stones: Excess calcium increase the risk of
can lead to the formation of cardiovascular disease.
kidney stones.

4) Interactions with Medications: 5) Hypercalcemia: Excessive

Calcium can interfere with the calcium levels in the blood can
absorption of certain cause confusion, fatigue, bone
medications, including antibiotics pain, and abnormal heart
and osteoporosis drugs. rhythms.
 Food/Diet Rich in calcium rich foods for bones are essential
Textskeleton health
for maintaining strong
through out life . to Text
get enough calcium ,

Calcium you should aim to eat a variety of calcium

rich foods through out the day .there are
calcium is a mineral that primarily functions in some food rich in calcium;
your body by making your bones and teeth hard yogurt , beans ,milk , canned fish, cottage
(99 %) cheese , broccoli, soy milk
The rest (1%) is in your blood and soft tissues, it
helps ;
1) your muscles to contract
2) your blood to clot. Dolomites are the most beautiful
3) helps your nervous system mountain ranges in Europe
( Italy) which are the combination
work properly.
of calcium / magnesium
carbonates
DIET.
1) diet with high sodium and animal protein In addition, there is limestone ,
chalk , marble.
increases the renal loss of calcium
2) diet with high phosphate and fiber Fo o d .
decrease the absorption of calcium
Thank you for your
attention