CEREBROSPINAL FLUID (CSF)

Circulation

Presented By
o Kaneez Riza E Rab Ameen
o Anuja Laxman Chaudhari
o Gautam Sunil Dugad
o Vaishnavi Anteshwar
Honrao
o Manaswi Gunwant
Kubade
o Ruchi Ambadas Meshram
o Pranav Vishnu Pawar
o Kartikeya Santosh Sawai
o Ruchita Naresh Sonwane
CEREBROSPINAL FLUID (CSF)
Circulation

What is CSF?
Government Medical College
Bhandara
Presented By
o Kaneez Riza E Rab Ameen
o Anuja Laxman Chaudhari
o Gautam Sunil Dugad
o Vaishnavi Anteshwar Honrao
o Manaswi Gunwant Kubade
o Ruchi Ambadas Meshram
o Pranav Vishnu Pawar
o Kartikeya Santosh Sawai
o Ruchita Naresh Sonwane
o Raj Rajesh Ukey
CEREBROSPINAL FLUID (CSF)
Circulation What is CSF?
 A clear, colorless fluid surrounding the brain & spinal cord.
Government Medical College
Functions:
Bhandara
 ✅ Acts as a cushion to protect the brain from injury.
Presented By
o Kaneez
✅ Removes
Riza E Rab Ameen waste & delivers nutrients to the brain.
o Anuja Laxman Chaudhari
o Gautam
✅ Maintains
Sunil Dugad pressure balance within the brain.
o Vaishnavi Anteshwar Honrao
o Manaswi Gunwant Kubade
 Location: Found in the brain’s ventricles, subarachnoid
o Ruchi Ambadas Meshram
o Pranav Vishnu Pawar
o space, and spinal cord.
Kartikeya Santosh Sawai
o Ruchita Naresh Sonwane
o Raj Rajesh Ukey
CEREBROSPINAL FLUID (CSF)
Circulation

Where CSF Comes From?

Government Medical College
Bhandara
Presented By
o Kaneez Riza E Rab Ameen
o Anuja Laxman Chaudhari
o Gautam Sunil Dugad
o Vaishnavi Anteshwar Honrao
o Manaswi Gunwant Kubade
o Ruchi Ambadas Meshram
o Pranav Vishnu Pawar
o Kartikeya Santosh Sawai
o Ruchita Naresh Sonwane
o Raj Rajesh Ukey
 CEREBROSPINAL FLUID (CSF)
Where CSF Comes From?
Circulation
 Produced by: Choroid plexus (specialized tissue in brain
Government
ventricles).Medical College
 Bhandara
Daily Production: 500 mL of CSF.
 Presented
Circulating
By Volume: 150 mL at any time.
 ooAbsorption:
Kaneez Riza E Rab Ameen
Old CSF is drained into the bloodstream via
Anuja Laxman Chaudhari

oarachnoid granulations.
o Gautam Sunil Dugad
Vaishnavi Anteshwar Honrao
 oContinuous Process: New CSF constantly replaces the old one.
Manaswi Gunwant Kubade
o Ruchi Ambadas Meshram
o Pranav Vishnu Pawar
o Kartikeya Santosh Sawai
o Ruchita Naresh Sonwane
o Raj Rajesh Ukey
CEREBROSPINAL FLUID (CSF)
Circulation

Government Medical College

CSF Circulation Pathway
Bhandara
Presented By
o Kaneez Riza E Rab Ameen
o Anuja Laxman Chaudhari
o Gautam Sunil Dugad
o Vaishnavi Anteshwar Honrao
o Manaswi Gunwant Kubade
o Ruchi Ambadas Meshram
o Pranav Vishnu Pawar
o Kartikeya Santosh Sawai
o Ruchita Naresh Sonwane
o Raj Rajesh Ukey
 CEREBROSPINAL FLUID (CSF)
CSF Circulation Pathway
Circulation
1️⃣Production: Lateral ventricles (Choroid plexus).
2️⃣Flow to Third Ventricle: Through Interventricular Foramen (Foramen
Government Medical College
of Monro).
Bhandara
3️⃣Flow to Fourth Ventricle: Via Cerebral Aqueduct (Aqueduct of
Sylvius).
Presented By
o Kaneez Riza E Rab Ameen
4️⃣Entry intoChaudhari
o Anuja Laxman Subarachnoid Space: Through Foramen of Magendie &
o Gautam Sunil Dugad
Foramina of Luschka.
o Vaishnavi Anteshwar Honrao
5️⃣Circulation: Around the brain & spinal cord.
o Manaswi Gunwant Kubade
o Ruchi Ambadas Meshram
6️⃣Absorption:
o Pranav Vishnu PawarInto the bloodstream via arachnoid granulations in
dural venous sinuses.
o Kartikeya Santosh Sawai
o Ruchita Naresh Sonwane
o Raj Rajesh Ukey
CEREBROSPINAL FLUID (CSF)
Circulation

Functions of CSF
Government Medical College
Bhandara
Presented By
o Kaneez Riza E Rab Ameen
o Anuja Laxman Chaudhari
o Gautam Sunil Dugad
o Vaishnavi Anteshwar Honrao
o Manaswi Gunwant Kubade
o Ruchi Ambadas Meshram
o Pranav Vishnu Pawar
o Kartikeya Santosh Sawai
o Ruchita Naresh Sonwane
o Raj Rajesh Ukey
CEREBROSPINAL FLUID (CSF)
Functions of CSF
Circulation
Protection
Acts as a shock absorber, cushioning the brain & spinal
Government Medical College
cord.
Bhandara
⚖️ Buoyancy
Presented By
o Kaneez Riza E Rab Ameen
Reduces the brain’s effective weight from 1400g to 50g,
o Anuja Laxman Chaudhari
preventing
o Gautam Sunil Dugad excess pressure on the brainstem.
o Vaishnavi Anteshwar Honrao
o Manaswi Gunwant Kubade
o Ruchi Ambadas Meshram
♻️Waste Removal & Nutrient Transport
o Pranav Vishnu Pawar
Removes metabolic waste from the brain.
o Kartikeya Santosh Sawai
o Ruchita Naresh Sonwane
Delivers oxygen, glucose, and essential nutrients to brain
o Raj Rajesh Ukey
CEREBROSPINAL FLUID (CSF)
Circulation

What is Hydrocephalus?
Government Medical College
Bhandara
Presented By
o Kaneez Riza E Rab Ameen
o Anuja Laxman Chaudhari
o Gautam Sunil Dugad
o Vaishnavi Anteshwar Honrao
o Manaswi Gunwant Kubade
o Ruchi Ambadas Meshram
o Pranav Vishnu Pawar
o Kartikeya Santosh Sawai
o Ruchita Naresh Sonwane
o Raj Rajesh Ukey
CEREBROSPINAL FLUID (CSF)
What
Circulation is Hydrocephalus?

🧠 Definition:
Government Medical College
ABhandara
condition where excess CSF accumulates in the brain, causing increased
intracranial pressure.
Presented By
What
o KaneezHappens?
Riza E Rab Ameen
❌oo CSF buildup
Anuja Laxman due to blockage, poor absorption, or overproduction.
Chaudhari
Gautam Sunil Dugad
📏o Ventricular
Vaishnavi Anteshwarenlargement
Honrao → Can lead to brain damage if untreated.
o Manaswi Gunwant Kubade
o Ruchi Ambadas Meshram
o Pranav Vishnu Pawar
o Kartikeya Santosh Sawai
o Ruchita Naresh Sonwane
o Raj Rajesh Ukey
CEREBROSPINAL FLUID (CSF)
What
Circulation is Hydrocephalus?
Types of Hydrocephalus
1
1️⃣ Communicating Hydrocephalus – CSF flows
Government Medical College
between
Bhandara ventricles but isn’t properly absorbed.
2️⃣ Non-Communicating (Obstructive) Hydrocephalus
–Presented
A By
blockage prevents CSF flow out of ventricles.
o Kaneez Riza E Rab Ameen
3️⃣
o Anuja Laxman Chaudhari
o Gautam Sunil Dugad
Normal Pressure Hydrocephalus (NPH) – Affects
older adults,
o Vaishnavi Anteshwarcausing:
Honrao
o Manaswi Gunwant Kubade
🚶o Gait disturbances
Ruchi Ambadas Meshram
o Pranav Vishnu Pawar
🧠o Memory loss
Kartikeya Santosh Sawai
🚽oo Urinary incontinence
Ruchita Naresh
Raj Rajesh Ukey
Sonwane
CEREBROSPINAL FLUID (CSF)
What
Circulation is Hydrocephalus?
Congenital vs. Acquired Hydrocephalus
Government Medical College
•Bhandara
Congenital: Present at birth (e.g., aqueductal stenosis, neural tube
defects).
•Presented By
Acquired: Develops later due to injury, infection, or tumor.
o Kaneez Riza E Rab Ameen
o Anuja Laxman Chaudhari
o Gautam Sunil Dugad
o Vaishnavi Anteshwar Honrao
o Manaswi Gunwant Kubade
o Ruchi Ambadas Meshram
o Pranav Vishnu Pawar
o Kartikeya Santosh Sawai
o Ruchita Naresh Sonwane
o Raj Rajesh Ukey
CEREBROSPINAL FLUID (CSF)
Circulation

Causes of Hydrocephalus
Government Medical College
Bhandara
Presented By
o Kaneez Riza E Rab Ameen
o Anuja Laxman Chaudhari
o Gautam Sunil Dugad
o Vaishnavi Anteshwar Honrao
o Manaswi Gunwant Kubade
o Ruchi Ambadas Meshram
o Pranav Vishnu Pawar
o Kartikeya Santosh Sawai
o Ruchita Naresh Sonwane
o Raj Rajesh Ukey
CEREBROSPINAL FLUID (CSF)
Causes
Circulation of Hydrocephalus
🔴 Blockage (Obstruction)
Most common cause – Tumors, cysts, or infections block CSF flow within ventricles.
Government
⚠️Poor Absorption Medical College
Bhandara
Arachnoid granulations fail to absorb CSF due to infections, bleeding, or inflammation.
📈Presented
Overproduction
By
of CSF (Rare)
Choroid plexus
o Kaneez Riza tumors may produce excess CSF, leading to accumulation.
E Rab Ameen
o Anuja Laxman Chaudhari
Common Risk Factors
o Gautam Sunil Dugad
🍼o Premature birth
Vaishnavi Anteshwar – Risk of brain bleeding.
Honrao
🦠oo Meningitis
Manaswi Gunwant Kubade
or brain infections – Can damage CSF absorption pathways.
Ruchi Ambadas Meshram
💥o Head injury
Pranav Vishnu or stroke – May disrupt normal CSF flow.
Pawar
🧬oo Genetic
Kartikeya Santosh Sawai
disorders – Affect CSF circulation & drainage.
Ruchita Naresh Sonwane
o Raj Rajesh Ukey
CEREBROSPINAL FLUID (CSF)
Circulation

Signs & Symptoms

Government Medical College
Bhandara

of Hydrocephalus
Presented By
o Kaneez Riza E Rab Ameen
o Anuja Laxman Chaudhari
o Gautam Sunil Dugad
o Vaishnavi Anteshwar Honrao
o Manaswi Gunwant Kubade
o Ruchi Ambadas Meshram
o Pranav Vishnu Pawar
o Kartikeya Santosh Sawai
o Ruchita Naresh Sonwane
o Raj Rajesh Ukey
 CEREBROSPINAL FLUID (CSF)
Signs & Symptoms
Circulationof Hydrocephalus

🍼 InGovernment
Infants (BeforeMedical Skull Bones Fuse)
College 🧓 In Normal Pressure Hydrocephalus (NPH -
 Enlarged
Bhandara head (bulging fontanelles). Elderly)
 Sunset sign (downward-looking eyes). ⚠️Classic Triad of Symptoms:
Presented By
 Irritability,
o Kaneez Riza Epoor feeding, vomiting.
Rab Ameen 1 Gait disturbances (shuffling walk).
1️⃣
o Anuja Laxman Chaudhari
o Gautam Sunil Dugad 2️⃣Dementia-like memory loss.
👦 In Older Children & Adults
o
o
Vaishnavi Anteshwar Honrao
3️⃣Urinary incontinence (bladder control
Manaswi Gunwant Kubade
 Morning headaches, nausea, vomiting.
o Ruchi Ambadas Meshram loss).
 Blurred vision & difficulty walking.
o
o
Pranav Vishnu Pawar
Kartikeya Santosh Sawai
 Memory problems & confusion.
o Ruchita Naresh Sonwane
o Raj Rajesh Ukey
CEREBROSPINAL FLUID (CSF)
Circulation

How Hydrocephalus
Government Medical College
Bhandara
Presented Byis Diagnosed
o Kaneez Riza E Rab Ameen
o Anuja Laxman Chaudhari
o Gautam Sunil Dugad
o Vaishnavi Anteshwar Honrao
o Manaswi Gunwant Kubade
o Ruchi Ambadas Meshram
o Pranav Vishnu Pawar
o Kartikeya Santosh Sawai
o Ruchita Naresh Sonwane
o Raj Rajesh Ukey
 How Hydrocephalus
CEREBROSPINAL FLUID (CSF)
is Diagnosed
Circulation
CT Scan (Computed Tomography)
✔️Quickly detects ventricular enlargement.

🧲Government
MRI (Magnetic Resonance Imaging)
Medical College
✔️Provides
Bhandara detailed images of CSF blockages & brain damage.

👶Presented
Ultrasound
By (For Infants)
o Kaneez Riza E Rab Ameen
✔️Used whenChaudhari
o Anuja Laxman fontanelles are open to check for fluid buildup.
o Gautam Sunil Dugad
o Vaishnavi Anteshwar Honrao
💉oLumbar Puncture
Manaswi Gunwant (Spinal Tap)
Kubade
o Ruchi AmbadasCSF
✔️Measures pressure in the spine.
Meshram
o Pranav Vishnu Pawar
o Kartikeya Santosh Sawai
📊oIntracranial Pressure (ICP) Monitoring
Ruchita Naresh Sonwane
o Raj Rajesh Ukey
✔️Used in severe cases to detect dangerously high pressure inside the skull.
CEREBROSPINAL FLUID (CSF)
Circulation

Government Medical College

Treatment of Hydrocephalus
Bhandara
Presented By
o Kaneez Riza E Rab Ameen
o Anuja Laxman Chaudhari
o Gautam Sunil Dugad
o Vaishnavi Anteshwar Honrao
o Manaswi Gunwant Kubade
o Ruchi Ambadas Meshram
o Pranav Vishnu Pawar
o Kartikeya Santosh Sawai
o Ruchita Naresh Sonwane
o Raj Rajesh Ukey
CEREBROSPINAL FLUID (CSF)
Treatment of Hydrocephalus
Circulation
🔹 Surgical Options
🩺 Ventriculoperitoneal (VP) Shunt
Government
✔️A Medical
tube (shunt) College
drains excess CSF from the brain to the abdomen, where it’s
Bhandara
absorbed.
Presented Bycommon treatment.
✔️Most
o Kaneez Riza E Rab Ameen
o Anuja Laxman Chaudhari
o Gautam Sunil Dugad
🔹 Endoscopic Third Ventriculostomy (ETV)
o Vaishnavi Anteshwar Honrao
✔️A small hole is created in the third ventricle to bypass blockages.
o
o
Manaswi Gunwant Kubade
Ruchi Ambadas Meshram
✔️Used for non-communicating hydrocephalus.
o Pranav Vishnu Pawar
o Kartikeya Santosh Sawai
o Ruchita Naresh Sonwane
o Raj Rajesh Ukey
CEREBROSPINAL FLUID (CSF)
Treatment of Hydrocephalus
Circulation
💊 Medications (Temporary Relief Only)
✔️Acetazolamide & Furosemide – Reduce CSF production temporarily but
Government
aren’t Medical
permanent College
solutions.
Bhandara
🔹Presented
Treating By the Underlying Cause
o Kaneez Riza E Rab Ameen
✔️Antibiotics – For infections like meningitis.
o Anuja Laxman Chaudhari
o Gautam Sunil Dugad
✔️Tumor removal
o Vaishnavi Anteshwar – If a tumor is blocking CSF flow.
Honrao
o Manaswi Gunwant Kubade
o Ruchi Ambadas Meshram
o Pranav Vishnu Pawar
o Kartikeya Santosh Sawai
o Ruchita Naresh Sonwane
o Raj Rajesh Ukey
CEREBROSPINAL FLUID (CSF)
Circulation

Additional Information on
Government Medical College
Bhandara
CSF & Hydrocephalus
Presented By
o Kaneez Riza E Rab Ameen
o Anuja Laxman Chaudhari
o Gautam Sunil Dugad
o Vaishnavi Anteshwar Honrao
o Manaswi Gunwant Kubade
o Ruchi Ambadas Meshram
o Pranav Vishnu Pawar
o Kartikeya Santosh Sawai
o Ruchita Naresh Sonwane
o Raj Rajesh Ukey
CEREBROSPINAL FLUID (CSF)
Additional Information on
Circulation
CSF & Hydrocephalus
CSF Pressure & Regulation ⚖️
✅Government Medical
Normal CSF Pressure: 7-15College
mmHg (adults).
❌Bhandara
High Pressure: Hydrocephalus, brain herniation risk.
❌ Low Pressure: CSF leaks, severe headaches.
Presented By
o Kaneez Riza E Rab Ameen
Complications of Untreated Hydrocephalus ⚠️
o Anuja Laxman Chaudhari
o Gautam Sunil Dugad
o Brain damage
Vaishnavi Anteshwar(prolonged
Honrao pressure on neurons).
o Vision
Manaswiloss (optic
Gunwant nerve compression).
Kubade
o Ruchi Ambadas Meshram
o Cognitive
Pranav Vishnu& developmental delays (in children).
Pawar
o Kartikeya Santosh Sawai
o Ruchita Naresh Sonwane
o Raj Rajesh Ukey
CEREBROSPINAL FLUID (CSF)
Additional Information on
Circulation
CSF & Hydrocephalus
Recent Advances in Treatment 🏥
🔹Government Medical
Programmable Shunts CollegeCSF drainage without surgery.
– Adjustable
🔹Bhandara
Neuroendoscopic Procedures – Less invasive with fewer risks.
🔹 Artificial CSF Research – Potential future therapy for brain protection.
Presented By
o Kaneez Riza E Rab Ameen
o Anuja Laxman Chaudhari
o Gautam Sunil Dugad
o Vaishnavi Anteshwar Honrao
o Manaswi Gunwant Kubade
o Ruchi Ambadas Meshram
o Pranav Vishnu Pawar
o Kartikeya Santosh Sawai
o Ruchita Naresh Sonwane
o Raj Rajesh Ukey