FLEMMING COLLEGE OF
PHARMACY
SUBJECT:-PHARMACEUTICAL INORGANIC CHEMISTRY
TOPIC:-BRIEFLY DESCRIBE ABOUT GASTROINTESTINAL
AGENTS
PRESENTED BY:-SUBHARAJ PAL
ROLL NO:-FCP/B/2024/022
COURSE:-B PHARM ,1ST YEAR
YEAR:2024-28
CONTENT
Introduction
Gastrointestinal track
Acidifiers
Antacids
laxatives
Adsorbent
INTRODUCTION
•Used for managing condition such as acid
reflux, ulcers Medications used to treat
conditions affecting the gastrointestinal
(GI) tract.
•Aim to manage symptoms such as acid
reflux, diarrhea, constipation, and
inflammation.
•Categories include antacids, laxatives,
antidiarrheal agents, and more.
G A S T R O I N T E S T I N A L T RAC K
The digestive system is the Gastrointestinal tract (GIT) which is a
group of organs.
It extends from Alimentary canal to the anus.
The entrance to the system is the buccal cavity i.e. mouth.
The main portions of GIT include-
1. Stomach
2. Small Intestine - i) Duodenum ii) jejunum
ii)ileum
3. Large Intestine -i) Caecum ii) Ascending
colon
iii) Transverse colon
iv) Descending coloni
v) Rectum with the exit anus
ACIDIFIERS
• Acidifiers are the drugs or agents ,which are used to treat acid-base
imbalance in the body or for the treatment of metabolic alkalosis
• Acidifiers are the agents, which are used to neutralize the PH which has
been increased due to certain causes like excess alkali intake.
• Normal urinary-PH-7
• E.g:-Dilute HCL
A N TA C I D S
• Purpose: Neutralize stomach(HCl) acid.
■ Examples:
• Aluminium hydroxide
•Magnesium hydroxide
• Calcium carbonate
• Indications: Heartburn, indigestion.
E.g:-Sodium bicarbonate
LAXATIVES
These are drugs that promote
evacuation of bowels.
A distinction is sometimes made
according to the intensity of action.
(a) Laxative or aperient: milder action,
elimination of soft but formed stools.
(b) Purgative or cathartic: stronger
action resulting in more fluid
evacuation.
Many drugs in low doses act as laxative
and in larger doses as purgative.
ADSORBENT
These are chemically inert substances which are used in the
treatment of mild diarrhoea or dysentery of GIT because of
their ability to adsorb gases, toxins and bacteria
E.g:- Bismuth subcarbonate ,
Bismuth subnitrate
milk of Bismuth.
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