   Introduction

    Definition of Flow
   Types of Flow

    Factors Affecting Flow
   Clinical Applications
   Conclusion
   A fluid is a state of matter (or matter- in-
    transition) in which its molecules move freely
    and do not bear a constant relationship in
    space to other molecules


    Thus it has the ability to take up the shape of
    its container
Fluids are

    Liquid
          e.g. blood, i.v. infusions
   Gas
          e.g. O2 , N2O
   Vapour (transition from liquid to gas)
          e.g. N2O (under compression in cylinder), volatile inhalational
           agents (halothane, isoflurane, etc)
   Sublimate (transition from solid to gas bypassing liquid
    state)
          Dry ice (solid CO2), iodine
   Flow is defined as the quantity of fluid (gas, liquid,
    vapour or sublimate) that passes a point per unit time
   A simple equation to represent this is:

              Flow (F) = Quantity (Q)
                           Time (t)

   Flow is sometimes written as ∆Q (rate of change of a
    quantity)
   There are two types of flow:

       Laminar flow

       Turbulent flow
   Smooth, steady and orderly flow of fluid in a tube
   All the fluid molecules move in a straight line
   Therefore they move in parallel layers or laminae with
    no disruption between the layers
   Velocity of flow is greatest in the axial stream (centre
    of the tube). It becomes progressively slower as the
    layers move to the periphery
   Axial stream velocity is twice the mean flow velocity
   Velocity of the layer in contact with the wall is virtually
    zero
Diagrammatic representation of laminar flow
   Fluid does not move in orderly manner

    The fluid molecules become more disorganized
   They form swirls and eddies as they move down the
    pressure gradient in haphazard manner

    There is increased resistance to flow as the eddy
    currents interfere with each other
   Therefore greater energy is required for a given flow
    rate, compared to when the flow is laminar
Diagrammatic representation of turbulent flow
   Pressure: flow is directly proportional to the pressure
    difference across the tube
          Q ∞ ∆P
   Radius: flow is directly proportional to the fourth power
    of the radius (or diameter) of the tube
          Q ∞ r4, or Q ∞ d4
   Length: flow is inversely proportional to the length of the
    tube
          Q ∞ 1/l
   Viscosity: flow is inversely proportional to the viscosity of
    the fluid
          Q ∞ 1/η
 The relationship between pressure and flow is
  linear within certain limits
 As velocity increases, a critical point (or critical
  velocity) is reached where flow changes from
  laminar to turbulent
 Beyond this point, flow is proportional to the
  square root of pressure gradient
   This number is calculated from an equation that
    incorporates the factors that determine the critical
    point

        Reynolds’ number = vρr              or    vρd
                           η                       η
                     v = velocity of fluid flow
                     ρ = density of fluid
                     r = radius of tube
                     d = diameter of tube
                     η = viscosity of fluid


   Reynolds number does not have any associated unit
   It is a dimensionless number
   if Reynolds’ number exceeds 2000, flow is likely to be
    turbulent

   a Reynolds’ number of less than 2000 is usually
    associated with laminar flow
   Viscosity (η) is the property of a fluid that causes it to
    resist flow
   It is a measure of the frictional forces acting
    between the layers of fluid as it flows along the tube

       η = force x velocity gradient
            area

   Unit of viscosity is pascal second (Pa s)
 Viscosity of a liquid decreases with increased
  temperature, while viscosity of a gas increases with
  increased temperature
 From Hagen-Poiseuille equation, the more viscous a
  fluid is the lesser the flow. This however applies to
  laminar flow and not turbulent flow, where flow is
  dependent on the density of the fluid
   Density (ρ) is defined as mass per unit volume

   Unit of density is kilogram per meter cube
    (kgm-3)

   Density is an important factor of fluid in turbulent
    flow through a tube, in which flow is inversely
    proportional to square root of density
   In a tube, the length of the fluid pathway is greater than
    the diameter
                                                   diameter



                               length

   In an orifice, the diameter of the fluid pathway is
    greater than the length
                                        diameter


                                   length
 As the diameter of a tube increases, the Reynolds
  number increases. Eventually if the diameter of the
  tube increases enough, it will exceed the length of the
  tube. We then call this an orifice
 Flow through a tube is laminar and hence dependent
  on viscosity (provided that the critical velocity is not
  exceeded)
 If the flow is through an orifice it is turbulent and
  dependent on density
   The flow rate of a fluid through an orifice is
    dependent upon:
     the square root of the pressure difference across
      the orifice
     the square of the diameter of the orifice

     the density of the fluid (flow through an orifice

      inevitably involves some degree of turbulence)
   There are two types

       Variable orifice (fixed pressure change) flowmeters
              e.g Rotameter, peak flowmeter

       Variable pressure change (fixed orifice) flowmeters
              e.g. Bourdon gauge, pneumotacograph
   At low flows, the bobbin is near the bottom of the tube
    and the gap between the bobbin and wall of the
    flowmeter acts like a tube (diameter < length)
   Gas flow is laminar and hence the viscosity of the gas is
    important
   As flow rate increases, the bobbin rises up the
    flowmeter and the gap increases until it eventually acts
    like an orifice (diameter > length)
   At this point the density of the gas affects its flow
   This useful clinical instrument is capable of measuring
    flow rates up to 1000 L per min
   Air flow causes a vane to rotate or a piston to move
    against the constant force of a light spring
   This opens orifices which permit air to escape
   The vane or piston rapidly attains a maximum position
    in response to the peak expiratory flow
   It is held in this position by a ratchet
   The reading is obtained from a mechanical pointer
    which is attached to the vane or piston
   Accurate results demand good technique

       These devices must be held horizontally to minimize the
        effects of gravity on the position of the moving parts

       The patient must be encouraged to exhale as rapidly as
        possible
   Bourdon gauge is used to sense the pressure change
    across an orifice and is calibrated to the gas flow rate
   It uses a coiled tube which uncoils as pressure increases
   A system of cogs converts uncoiling of the coil into
    clockwise movement of the needle over a calibrated
    scale
   These rugged meters are not affected by changes in
    position and are useful for metering the flow from gas
    cylinders at high ambient pressure
   Measures flow rate by sensing the pressure change across a
    small but laminar resistance
   Uses differential manometer that senses the true lateral
    pressure exerted by the gas on each side of the resistance
    element and transduce them to a continuous electrical
    output
   It is a sensitive instrument with a rapid response to
    changing gas flow
   It is used widely for clinical measurement of gas flows in
    respiratory and anaesthetic practice
   However, practical application requires frequent calibration
    and correction or compensation for differences in
    temperature, humidity, gas composition and pressure
    changes during mechanical ventilation.
 Resistance to breathing is much greater when an
  endotracheal tube of small diameter is used
 Flow is significantly reduced in proportion to the fourth
  power of the diameter
       changing the tube from an 8mm to a 4mm may reduce flow by
        up to sixteen-fold
 Therefore the work of breathing is significantly
  increased
 Over time, a spontaneously breathing patient becomes
  exhausted and soon becomes hypercapnic due to
  reduced respiration
   In anaesthetic breathing systems, the following can
    cause turbulent flow, making the work of breathing
    greater
    ›   a sudden change in diameter of tubing
    ›   irregularity of the wall
    ›   acute angles at connections
    ›   Unnecessary long circuits
 Thus, breathing tubes should possess smooth internal
  surfaces, gradual bends and no constrictions
 They should be of as large a diameter and as short a
  length as possible
   Heliox is a mixture of 21% oxygen and 79% helium
   Helium is an inert gas that is much less dense than nitrogen
    (79% of air)
   Heliox much less dense than air
   In patients with upper airway obstruction, flow is turbulent
    and dependent on the density of the gas passing through it
   Therefore for a given patient effort, there will be a greater
    flow of heliox (density = 0.16) than air (density = 1.0) or
    oxygen alone (density = 1.3)
   However, heliox contains 21% oxygen – it may be of lesser
    benefit in hypoxic patient
   Humidification, in addition to its other benefits, makes
    inspired gas less dense

   This may be of benefit by reducing the work of
    breathing
   For a given fluid, with the same pressure applied to it,
    flow is greater through a shorter, wider cannula
    Thus they are preferred in resuscitation

    Flow is principally laminar


    There is a possibility of turbulence at the
    junction of the vessels or where vessels
    are constricted by outside pressure

   Here turbulence results in a bruit which is
    heard on auscultation
   As fluid passes through a constriction, there is an increase
    in velocity of the fluid
   Beyond the constriction, velocity decreases to the initial
    value
   At point A, the energy in the fluid is both potential and
    kinetic
   At point B the amount of kinetic energy is much greater
    because of the increased velocity
   As the total energy state must remain constant, potential
    energy is reduced at point B and this is reflected by a
    reduction in pressure
 In the Venturi tube, the pressure is least at the site of
  maximum constriction
 Subatmospheric pressure may be induced distal to the
  constriction by gradual opening of the tube beyond the
  constriction
 describes a phenomenon whereby gas flow through a
  tube with two Venturis tends to cling either to one side
  of the tube or to the other
 used in anaesthetic ventilators (fluidic ventilators), as
  the application of a small pressure distal to the
  restriction may enable gas flow to be switched from
  one side to another
Fluid flow and measurement
Fluid flow and measurement
Fluid flow and measurement
Fluid flow and measurement

Fluid flow and measurement

  • 2.
    Introduction  Definition of Flow  Types of Flow  Factors Affecting Flow  Clinical Applications  Conclusion
  • 3.
    A fluid is a state of matter (or matter- in- transition) in which its molecules move freely and do not bear a constant relationship in space to other molecules  Thus it has the ability to take up the shape of its container
  • 4.
    Fluids are  Liquid  e.g. blood, i.v. infusions  Gas  e.g. O2 , N2O  Vapour (transition from liquid to gas)  e.g. N2O (under compression in cylinder), volatile inhalational agents (halothane, isoflurane, etc)  Sublimate (transition from solid to gas bypassing liquid state)  Dry ice (solid CO2), iodine
  • 5.
    Flow is defined as the quantity of fluid (gas, liquid, vapour or sublimate) that passes a point per unit time  A simple equation to represent this is: Flow (F) = Quantity (Q) Time (t)  Flow is sometimes written as ∆Q (rate of change of a quantity)
  • 6.
    There are two types of flow:  Laminar flow  Turbulent flow
  • 7.
    Smooth, steady and orderly flow of fluid in a tube  All the fluid molecules move in a straight line  Therefore they move in parallel layers or laminae with no disruption between the layers  Velocity of flow is greatest in the axial stream (centre of the tube). It becomes progressively slower as the layers move to the periphery  Axial stream velocity is twice the mean flow velocity  Velocity of the layer in contact with the wall is virtually zero
  • 8.
  • 9.
    Fluid does not move in orderly manner  The fluid molecules become more disorganized  They form swirls and eddies as they move down the pressure gradient in haphazard manner  There is increased resistance to flow as the eddy currents interfere with each other  Therefore greater energy is required for a given flow rate, compared to when the flow is laminar
  • 10.
  • 12.
    Pressure: flow is directly proportional to the pressure difference across the tube  Q ∞ ∆P  Radius: flow is directly proportional to the fourth power of the radius (or diameter) of the tube  Q ∞ r4, or Q ∞ d4  Length: flow is inversely proportional to the length of the tube  Q ∞ 1/l  Viscosity: flow is inversely proportional to the viscosity of the fluid  Q ∞ 1/η
  • 14.
     The relationshipbetween pressure and flow is linear within certain limits  As velocity increases, a critical point (or critical velocity) is reached where flow changes from laminar to turbulent  Beyond this point, flow is proportional to the square root of pressure gradient
  • 16.
    This number is calculated from an equation that incorporates the factors that determine the critical point Reynolds’ number = vρr or vρd η η v = velocity of fluid flow ρ = density of fluid r = radius of tube d = diameter of tube η = viscosity of fluid  Reynolds number does not have any associated unit  It is a dimensionless number
  • 17.
    if Reynolds’ number exceeds 2000, flow is likely to be turbulent  a Reynolds’ number of less than 2000 is usually associated with laminar flow
  • 18.
    Viscosity (η) is the property of a fluid that causes it to resist flow  It is a measure of the frictional forces acting between the layers of fluid as it flows along the tube η = force x velocity gradient area  Unit of viscosity is pascal second (Pa s)
  • 19.
     Viscosity ofa liquid decreases with increased temperature, while viscosity of a gas increases with increased temperature  From Hagen-Poiseuille equation, the more viscous a fluid is the lesser the flow. This however applies to laminar flow and not turbulent flow, where flow is dependent on the density of the fluid
  • 20.
    Density (ρ) is defined as mass per unit volume  Unit of density is kilogram per meter cube (kgm-3)  Density is an important factor of fluid in turbulent flow through a tube, in which flow is inversely proportional to square root of density
  • 21.
    In a tube, the length of the fluid pathway is greater than the diameter diameter length  In an orifice, the diameter of the fluid pathway is greater than the length diameter length
  • 22.
     As thediameter of a tube increases, the Reynolds number increases. Eventually if the diameter of the tube increases enough, it will exceed the length of the tube. We then call this an orifice  Flow through a tube is laminar and hence dependent on viscosity (provided that the critical velocity is not exceeded)  If the flow is through an orifice it is turbulent and dependent on density
  • 23.
    The flow rate of a fluid through an orifice is dependent upon:  the square root of the pressure difference across the orifice  the square of the diameter of the orifice  the density of the fluid (flow through an orifice inevitably involves some degree of turbulence)
  • 25.
    There are two types  Variable orifice (fixed pressure change) flowmeters  e.g Rotameter, peak flowmeter  Variable pressure change (fixed orifice) flowmeters  e.g. Bourdon gauge, pneumotacograph
  • 28.
    At low flows, the bobbin is near the bottom of the tube and the gap between the bobbin and wall of the flowmeter acts like a tube (diameter < length)  Gas flow is laminar and hence the viscosity of the gas is important  As flow rate increases, the bobbin rises up the flowmeter and the gap increases until it eventually acts like an orifice (diameter > length)  At this point the density of the gas affects its flow
  • 31.
    This useful clinical instrument is capable of measuring flow rates up to 1000 L per min  Air flow causes a vane to rotate or a piston to move against the constant force of a light spring  This opens orifices which permit air to escape  The vane or piston rapidly attains a maximum position in response to the peak expiratory flow  It is held in this position by a ratchet  The reading is obtained from a mechanical pointer which is attached to the vane or piston
  • 32.
    Accurate results demand good technique  These devices must be held horizontally to minimize the effects of gravity on the position of the moving parts  The patient must be encouraged to exhale as rapidly as possible
  • 33.
    Bourdon gauge is used to sense the pressure change across an orifice and is calibrated to the gas flow rate  It uses a coiled tube which uncoils as pressure increases  A system of cogs converts uncoiling of the coil into clockwise movement of the needle over a calibrated scale  These rugged meters are not affected by changes in position and are useful for metering the flow from gas cylinders at high ambient pressure
  • 35.
    Measures flow rate by sensing the pressure change across a small but laminar resistance  Uses differential manometer that senses the true lateral pressure exerted by the gas on each side of the resistance element and transduce them to a continuous electrical output  It is a sensitive instrument with a rapid response to changing gas flow  It is used widely for clinical measurement of gas flows in respiratory and anaesthetic practice  However, practical application requires frequent calibration and correction or compensation for differences in temperature, humidity, gas composition and pressure changes during mechanical ventilation.
  • 39.
     Resistance tobreathing is much greater when an endotracheal tube of small diameter is used  Flow is significantly reduced in proportion to the fourth power of the diameter  changing the tube from an 8mm to a 4mm may reduce flow by up to sixteen-fold  Therefore the work of breathing is significantly increased  Over time, a spontaneously breathing patient becomes exhausted and soon becomes hypercapnic due to reduced respiration
  • 41.
    In anaesthetic breathing systems, the following can cause turbulent flow, making the work of breathing greater › a sudden change in diameter of tubing › irregularity of the wall › acute angles at connections › Unnecessary long circuits  Thus, breathing tubes should possess smooth internal surfaces, gradual bends and no constrictions  They should be of as large a diameter and as short a length as possible
  • 42.
    Heliox is a mixture of 21% oxygen and 79% helium  Helium is an inert gas that is much less dense than nitrogen (79% of air)  Heliox much less dense than air  In patients with upper airway obstruction, flow is turbulent and dependent on the density of the gas passing through it  Therefore for a given patient effort, there will be a greater flow of heliox (density = 0.16) than air (density = 1.0) or oxygen alone (density = 1.3)  However, heliox contains 21% oxygen – it may be of lesser benefit in hypoxic patient
  • 43.
    Humidification, in addition to its other benefits, makes inspired gas less dense  This may be of benefit by reducing the work of breathing
  • 44.
    For a given fluid, with the same pressure applied to it, flow is greater through a shorter, wider cannula  Thus they are preferred in resuscitation
  • 45.
    Flow is principally laminar  There is a possibility of turbulence at the junction of the vessels or where vessels are constricted by outside pressure  Here turbulence results in a bruit which is heard on auscultation
  • 47.
    As fluid passes through a constriction, there is an increase in velocity of the fluid  Beyond the constriction, velocity decreases to the initial value  At point A, the energy in the fluid is both potential and kinetic  At point B the amount of kinetic energy is much greater because of the increased velocity  As the total energy state must remain constant, potential energy is reduced at point B and this is reflected by a reduction in pressure
  • 48.
     In theVenturi tube, the pressure is least at the site of maximum constriction  Subatmospheric pressure may be induced distal to the constriction by gradual opening of the tube beyond the constriction
  • 53.
     describes aphenomenon whereby gas flow through a tube with two Venturis tends to cling either to one side of the tube or to the other  used in anaesthetic ventilators (fluidic ventilators), as the application of a small pressure distal to the restriction may enable gas flow to be switched from one side to another

Editor's Notes

  • #3 Clinical Applications, especially as it relates to ANAESTHESIA
  • #6 ∆ = pronounced “delta”
  • #19 Velocity gradient is equal to the difference between velocities of different fluid molecules divided by the distance between molecules
  • #51 These masks, also termed high air flow oxygen enrichment (HAFOE) devices, provide a constant and predictable inspired oxygen concentration irrespective of the patient&apos;s ventilatory pattern. This is achieved by supplying the mask with oxygen and air at a high total flow rate.
  • #52 gradient. This results in water being drawn up through the tube and broken into a fine spray as it comes in contact with the high-speed gas jet