ka/ks

最新推荐文章于 2025-08-04 22:31:11 发布

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最新推荐文章于 2025-08-04 22:31:11 发布

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原文链接：http://www.cnblogs.com/liuhui0622/p/5923845.html

1. If dN/dS = 1, amino-acid substitutions may be largely neutral. However, there is also the
 possibility that positive selection just cancels purifying selection, so that some amino-
 acid substitutions were driven by natural selection. This situation is thus ambiguous.

2. If dN/dS < 1, purifying selection (selection against deleterious non-synonymous 
 substitutions) has definitely operated. Some amino-acid substitutions have been may
 caused by selection, just not enough to overcome the effects of purifying selection.

3. If dN/dS > 1, selection has caused some amino-acid substitutions. Some substitutions 
 also have been caused by genetic drift. Purifying selection also likely operates, may
 but is not strong enough to overcome the effects of positive selection.

转载于:https://www.cnblogs.com/liuhui0622/p/5923845.html