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Drug Study

This document summarizes information on two medications: Cefuroxime axetil and Aluminum hydroxide. 1) Cefuroxime axetil is an antibiotic used to treat various bacterial infections. Common side effects include GI issues like diarrhea. Nurses should monitor for signs of infection and assess renal and hepatic function. 2) Aluminum hydroxide is an antacid used to treat hyperacidity and gastric ulcers. It can cause constipation and decrease absorption of minerals. Nurses should assess for aluminum toxicity and monitor bone health.

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0% found this document useful (0 votes)
8K views8 pages

Drug Study

This document summarizes information on two medications: Cefuroxime axetil and Aluminum hydroxide. 1) Cefuroxime axetil is an antibiotic used to treat various bacterial infections. Common side effects include GI issues like diarrhea. Nurses should monitor for signs of infection and assess renal and hepatic function. 2) Aluminum hydroxide is an antacid used to treat hyperacidity and gastric ulcers. It can cause constipation and decrease absorption of minerals. Nurses should assess for aluminum toxicity and monitor bone health.

Uploaded by

loveskisses
Copyright
© Attribution Non-Commercial (BY-NC)
We take content rights seriously. If you suspect this is your content, claim it here.
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Download as DOCX, PDF, TXT or read online on Scribd
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Generic name, Classification Availability Indications Side effects Nursing

Brand name, responsibilities


Dosage

Cefuroxime axetil Antibiotic Tablets – 125, 250, Oral: GI: stomach Assessment
500mg; suspension • Pharyngitis, tonsillitis upset, diarrhea, • History: Hepatic
Cephalosporin – 125 mg/5mL; caused by Streptococcus loss of appetite, and renal
Ceftin powder for injection pyogenes nausea or impairment,
– 750 mg, 1.5g; • Otitis media caused by vomiting. lactation,
injection – 750 mg, Streptococcus pregnancy
Dosages: 1.5 g pneumonia, S.pyogenes, headache, • Physical: Skin
Oral Haemophilus influenza, dizziness, fatigue, status, LFTs,
Adults and Moraxella catarrhalis muscle aches, renal function
patients 12 yr and • Lower respiratory strange taste in the tests, culture of
older infections caused by mouth, persistent affected area,
250 mg bid. For S.pneumoniae, fever, easy sensitivity tests
severe infections Haemophilus bruising or
may be increased parainfluenzae, bleeding, Interventions
to 500mg bid. H.influenzae persistent sore • Culture
Treat up to 10 • UTI’s caused by E.coli, throat infection, and
days. Klebsiella pneumonia arrange for
• Uncomplicated gonorrhea sensitivity tests
Pediatric patients • Skin and skin structure before and
younger than 12 infections, including during therapy if
yr impetigo caused by expected
125 mg bid Streptococcus aureus, response is not
S.pyrogenes seen
• Treatment of early Lyme • Give oral drug
disesase with food to
decrease GI
upset and
enhance
absorption
• Give oral drug to
children who can
swallow tablets;
crushing the
drug results in a
bitter, unpleasant
taste
• Have vitamin K
available in case
hypoprothrombi
nemia occurs
• Discontinue if
hypersensitivity
reaction occurs

Teaching points
Oral drug
• Take full course
of therapy even
if you are feeling
better
• This drug is
specific for this
infection and
should not be
used to self-treat
other problems
• Swallow tablets
whole; do not
crush them. Take
the drug with
food.
• You may
experience these
side effects:
stomach upset or
diarrhea
• Report severe
diarrhea with
blood, pus, or
mucus; rash;
difficulty of
breathing;
unusual
tiredness,
fatigue; unusual
bleeding or
bruising; unusual
itching or
irritation.

Aluminum Antacid Tablets – 300, 500, • Symptomatic relief of GI: constipation; Assessment
hydroxide 600 mg; capsules – upset stomach associated intestinal • History: allergy
400, 500mg; with hyperacidity obstruction, to aluminum
suspension – 320 • Hyperacidity associated decreased products; gastric
Maalox mg/5mL, with peptic ulcer, absorption of outlet
450mg/5mL, gastritis, peptic fluoride, obstruction;
675mg/5mL; liquid esophagitis, gastric accumulation of hypertension,
– 600 mg/5mL hyperacidity, hiatal aluminum in heart failure,
hernia serum, bone, and hypophosphatem
• Unlabeled uses: CNS ia, lactation
Dosages: Prophylaxis of GI Musculoskeletal:o • Physical: bone
Adults bleeding, stress ulcer; steomalacia and strength, muscle
500 – 1500 mg 3-6 reduction of phosphate chronic phosphate strength;
times/day PO absorption in deficiency with auscultation, BP,
between meals and hyperphosphatemia in bone pain, malaise, peripheral
at bedtime patients with chronic muscular weakness edema;
renal failure abdominal
examination,
bowel sounds;
serum
phosphorus,
serum fluoride;
bone X-ray is
appropriate

Interventions
• Give hourly for
first 2wk when
used for acute
peptic ulcer;
during the
healing stage,
give 1-3 hr after
meals and at
bedtime
○ Warning:
do not
administe
r oral
drugs
within 1-
2 hr
antacid
administr
ation
• Have patient
chew tablets
thoroughly;
follow with a
glass of water
• Monitor serum
phosphorus
levels
periodically
during long-term
therapy.

Teaching points
• Take this drug
between meals
and at bedtime
• Do not take
maximum
dosage of
antacids for
longer than 2
weeks except
under medical
supervision
• Do not take this
drug with any
other oral
medications;
absorption of
those
medications can
be inhibited.
Take oral
medications at
least 1-2 hours
after aluminum
salt
• Constipation
may occur
• Report
constipation;
bone pain,
muscle
weakness; coffee
ground vomitus,
black tarry
stools, no relief
from symptoms
being treated

Essentiale Forte Hepatic protectors • ESSENTIAL Acute, subacute & chronic abdominal pain, Do not use Essentiale
E- solution hepatitis; toxic metabolic liver nausea, diarrhea in hypersensitivity or all
for intraveno diseases, intoxications (eg from and allergic ergy to any ingredients
Dosages: us drugs); infection, fatty reaction(skin rash) of the preparation. The
Essentiale injections in degeneration of the liver due to application of Essentiale
cap Maintenance vials 5 ml. alcohol, hypernutrition, DM, in newborn children is
therapy 1-2 cap • ESSENTIAL kwashiorkor, pregnancy; not safe. During
tid. Essentiale E FORTE cholestasis; pre- & post-op care, pregnancy women are
Forte N- Capsules esp in liver/gallbladder surgery recommended to consult
cap Intensive N30 or their health care
therapy 1-2 cap N100. provider prior to taking
tid for the 1st 2 • ESSENTIAL Essentiale.
mth. E N.
-solution for
intravenous
injection in
vials 5 ml.
• ESSENTIAL
E FORTE –
capsules
N50.
Essentiale
forte
contains
essential
phospholipid
s(EPL
substance)
300 mg,
Thiamine
mono
nitrate(Vitam
in B1)6 mg,
Riboflavine(
Vitamiin B2)
6 mg,
Pyridoxine
chidrochlorid
e
6mg(Vitamin
B6),
Cyanocobola
mine 0.06
mg (Vitamin
B12),
Nicotinamid
e 30mg,
Tocopherole
acetate 6
mg(Vitamin
E).

Omeprazole Antacids, DR capsules – 10, • Short-term treatment of Some of the most Assessment:
Antireflux Agents 20, 40 mg; DR active duodenal ulcer frequent side • History:
Risek Antiulcerants tablets – 20mg • First-line therapy in effects of hypersensitivity
(OTC); powder for treatment of heartburn or omeprazole to omeprazole or
Dosages: oral suspension – symptoms of GERD (experienced by any of its
• Cap Duode 20, 40 mg/packet • Short-term treatment of over 1% of those components;
nal active benign gastric taking the drug) pregnancy,
ulcer 20 ulcer are headache, diarr lactation
mg once • GERD, severe erosive hea, abdominal • Physical: skin
daily for 2- esophagitis, poorly pain,nausea, dizzin lesions; T;
4 wk. responsive symptomatic ess, trouble reflexes, affect,
• Gastric GERD awakening and urinary output,
ulcer & • Long-term therapy: sleep deprivation, abdominal
reflux treatment of pathologic although in clinical examination;
esophagiti hypersecretory conditions trials the incidence respiratory
s 20 mg (Zollinger-Ellison’s of these effects auscultation
once daily syndrome, multiple with omeprazole
w/ adenomas, systemic was mostly Intervention
amoxicillin mastocytosis) comparable to that • Administer
1.5-3 g • Eradication of found before meals.
daily in Helicobacter pylori with with placebo. Caution patient
divided amoxicillin or to swallow
doses for 2 metronidazole and Proton pump capsules whole –
wk. clarithromycin inhibitors may be not to open,
• Zollinger- • Unlabeled use: posterior associated with a chew, or crush
Ellison laryngitis; enhance greater risk of hip them. If using
syndrome efficacy of pancreatinin fractures, and clost oral suspension,
60 mg once for the treatment of ridium difficile- empty packet
daily. steatorrhea in cystic associated into a small cup
Doses >80 fibrosis. diarrhea. Patients containing 2 tbsp
mg should are frequently of water. Stir
be divided administered the and have patient
& drugs in intensive drink
administere care as a protective immediately; fill
d bid. measure against cup with water
• Vial GER ulcers, but this use and have patient
D, peptic is also associated drink this water.
ulcer with a 30% Do not use other
disease, increase in diluents.
NSAID- occurrence of
associated pneumonia. Teaching points
ulcer 40 • Take drug before
mg IV meals.
once daily. • Have regular
• Zollinger- medical follow-
Ellison up visits
syndrome • Report severe
Initially 60 headache,
mg IV worsening of
daily & symptoms, fever,
dose chills
adjusted
individuall
y. Dose
>60 mg
given bid.
• Prophylax
is of acid
aspiration
40 mg IV
completed
1 hr pre-
op.
• Eradicatio
n of H.
pylori 40
mg daily
combined
w/
antibacteria
ls in dual
therapy or
omeprazole
20 mg bid
w/
antibacteria
ls in triple
therapy.

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