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Fibroadenoma: Gross and Microscopic Features

Fibroadenoma is a benign breast tumour composed of both fibrous and epithelial elements. Microscopically, it is dominated by fibrous tissue and can exhibit one of two patterns - intracanalicular, where fibrous tissue invaginates into glandular tissue, or pericanalicular, where fibrous stroma surrounds mammary gland ducts. Fibroadenomas typically present as solitary, well-circumscribed masses in young women aged 15-30 years old.

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Aimanazrul Zainudin
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216 views11 pages

Fibroadenoma: Gross and Microscopic Features

Fibroadenoma is a benign breast tumour composed of both fibrous and epithelial elements. Microscopically, it is dominated by fibrous tissue and can exhibit one of two patterns - intracanalicular, where fibrous tissue invaginates into glandular tissue, or pericanalicular, where fibrous stroma surrounds mammary gland ducts. Fibroadenomas typically present as solitary, well-circumscribed masses in young women aged 15-30 years old.

Uploaded by

Aimanazrul Zainudin
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
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FIBROADENOMA

Histological appearance
And structure

Most common benign


tumour of female
breast

Fibrous + epithelial
elements

GROSS

solitary

Discrete
Well-circumscribed
Freely mobile
Encapsulated
15 30 (20-30) y/o

May become
malignant; CIS

2-3 cm

Spherical or discoid
mass

Cut surface appearance


Firm, grey-white, slightly myxoid
May form slit-like spaces by compressed
ducts

MICROSCOPIC STRUCTURE

Dominated by fibrous tissue

The arrangements of fibrous tissue and ducts


epithelium may produce two types of
patterns
intracanalicular and pericanalicular

THE EPITHELIAL TISSUE

The epithelial tissue is usually


lack of hyperchromatism and
pleomorphism

In some cases, hyperplasia can be marked. It


tends to occur more commonly in juvenile
fibroadenomas

Pericanalicular pattern
Masses of fibrous stroma around the ducts of
mammary gland

The fibrous stroma ; hyalinised collagen

Pericanalicular pattern

The compressed ducts show linear


branching pattern with slit-like lumens

Intracanalicular Pattern
stromal connective tissue invaginates into
the glandular component

Intracanalicular Pattern

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