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HIV and AIDS Activities > Antiretroviral drugs used in the treatment of HIV infection
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Antiretroviral drugs used in the treatment of HIV infection
Drugs Used in the Treatment of HIV Infection
Click on drug brand name for additional information.
Multi-class Combination Products
Brand Name
Generic Name
Atripla1
efavirenz, emtricitabine
and tenofovir disoproxil
fumarate
emtricitabine, rilpivirine,
and tenofovir disoproxil
fumarate
elvitegravir, cobicistat,
emtricitabine, tenofovir
disoproxil fumarate
Complera2
Stribild3
Manufacturer Name*
Approval Date Time to
Approval
Bristol-Myers Squibb and Gilead 12-July-06
2.5 months
Sciences
Gilead Sciences
10-August-11
6 months
Gilead Sciences
27-August-12
6 months
Nucleoside Reverse Transcriptase Inhibitors (NRTIs)
Brand Name
Generic Name
Combivir4
lamivudine and zidovudine GlaxoSmithKline
Approval Date Time to
Approval
27-Sep-97
3.9 months
Emtriva5
Gilead Sciences
GlaxoSmithKline
02-Jul-03
17-Nov-95
10 months
Epivir6
emtricitabine, FTC
lamivudine, 3TC
Epzicom7
abacavir and lamivudine
GlaxoSmithKline
02-Aug-04
10 months
Hivid8
19-Jun-92
7.6 months
19-Mar-87
3.5 months
14-Nov-00
10.9 months
02-Aug-04
5 months
31-Oct-00
9 months
9-Oct-91
6 months
26-Oct-01
5.9 months
Zerit 15
zalcitabine,
Hoffmann-La Roche
dideoxycytidine, ddC (no
longer marketed)
zidovudine,
GlaxoSmithKline
azidothymidine, AZT, ZDV
abacavir, zidovudine, and GlaxoSmithKline
lamivudine
tenofovir disoproxil
Gilead Sciences, Inc.
fumarate and
emtricitabine
enteric coated didanosine, Bristol Myers-Squibb
ddI EC
didanosine,
Bristol Myers-Squibb
dideoxyinosine, ddI
tenofovir disoproxil
Gilead
fumarate, TDF
stavudine, d4T
Bristol Myers-Squibb
24-Jun-94
5.9 months
Ziagen16
abacavir sulfate, ABC
17-Dec-98
5.8 months
Retrovir9
Trizivir10
Truvada11
Videx EC12
Videx13
Viread14
Manufacturer Name*
GlaxoSmithKline
4.4 months
Nonnucleoside Reverse Transcriptase Inhibitors (NNRTIs)
Brand Name
Generic Name
Manufacturer Name*
rilpivirine
Tibotec Therapeutics
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Approval Date Time to
Approval
20-May-11
10 months
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HIV and AIDS Activities > Antiretroviral drugs used in the treatment of HIV infection
Edurant 17
Intelence18
etravirine
Tibotec Therapeutics
18-Jan-08
Rescriptor19
delavirdine, DLV
Pfizer
4-Apr-97
6 months
8.7 months
Sustiva20
efavirenz, EFV
Bristol Myers-Squibb
17-Sep-98
3.2 months
Viramune21
nevirapine, NVP
Boehringer Ingelheim
21-Jun-96
3.9 months
Viramune XR22 nevirapine, NVP
Boehringer Ingelheim
25-Mar-11
9.9 months
(Im m e diate
R e le ase )
(Ex te nde d
R e le ase )
Protease Inhibitors (PIs)
Brand Name
Generic Name
Manufacturer Name*
Agenerase23
GlaxoSmithKline
Aptivus24
amprenavir, APV (no
longer marketed)
tipranavir, TPV
Approval Date Time to
Approval
15-Apr-99
6 months
Boehringer Ingelheim
22-Jun-05
6 months
Crixivan25
indinavir, IDV,
Merck
13-Mar-96
1.4 months
Fortovase26
saquinavir (no longer
Hoffmann-La Roche
marketed)
saquinavir mesylate, SQV Hoffmann-La Roche
7-Nov-97
5.9 months
6-Dec-95
3.2 months
Abbott Laboratories
15-Sep-00
3.5 months
GlaxoSmithKline
20-Oct-03
10 months
Norvir30
lopinavir and ritonavir,
LPV/RTV
Fosamprenavir Calcium,
FOS-APV
ritonavir, RTV
Abbott Laboratories
1-Mar-96
2.3 months
Prezista31
darunavir
Tibotec, Inc.
23-Jun-06
6 months
Reyataz32
atazanavir sulfate, ATV
20-Jun-03
6 months
Viracept 33
nelfinavir mesylate, NFV
Bristol-Myers Squibb
Agouron Pharmaceuticals
14-Mar-97
2.6 months
Approval Date Time to
Approval
13-Mar-03
6 months
Invirase27
Kaletra28
Lexiva29
Fusion Inhibitors
Brand Name
Generic Name
Manufacturer Name
Fuzeon34
enfuvirtide, T-20
Hoffmann-La Roche & Trimeris
Entry Inhibitors - CCR5 co-receptor antagonist
Brand Name
Generic Name
Manufacturer Name
Selzentry35
maraviroc
Pfizer
Approval Date Time to
Approval
06-August-07 8 months
HIV integrase strand transfer inhibitors
Brand Name
Generic Name
Manufacturer Name
Isentress36
raltegravir
Merck & Co., Inc.
Approval Date Time to
Approval
12--Oct-07
6 months
dolutegravir
GlaxoSmithKline
13-August-13
Tivicay37
38
6 months
*manufacturer/sponsor at time of approval
Generic drugs used in the Treatment of HIV Infection39
Approved and Tentatively Approved Antiretrovirals in Association with the President's Emergency Plan
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