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Drug 1

Benazepril is an ACE inhibitor used to treat hypertension. It works by inhibiting the conversion of angiotensin I to angiotensin II, reducing vasopressor activity and aldosterone secretion. Contraindications include hypersensitivity, bilateral renal artery stenosis, angioedema, pregnancy, and impaired renal function. Common adverse effects are headache, dizziness, fatigue, cough, and hypotension. Nursing considerations include monitoring for hypotension, electrolyte imbalances, and impaired renal function.

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Dexter Yauder
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51 views2 pages

Drug 1

Benazepril is an ACE inhibitor used to treat hypertension. It works by inhibiting the conversion of angiotensin I to angiotensin II, reducing vasopressor activity and aldosterone secretion. Contraindications include hypersensitivity, bilateral renal artery stenosis, angioedema, pregnancy, and impaired renal function. Common adverse effects are headache, dizziness, fatigue, cough, and hypotension. Nursing considerations include monitoring for hypotension, electrolyte imbalances, and impaired renal function.

Uploaded by

Dexter Yauder
Copyright
© Attribution Non-Commercial (BY-NC)
We take content rights seriously. If you suspect this is your content, claim it here.
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Download as DOCX, PDF, TXT or read online on Scribd
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DRUG

MECHANISM OF ACTION

CONTRAINDICATION

ADVERSE EFFECT

ACTIONS

NURSING CONSIDERATIONS Assessment History: Allergy tobenazepril or other ACE inhibitors, impaired renal function, CHF, salt or volume depletion, lactation, pregnancy Physical: Skin color, lesions, turgor; T; P, BP, peripheral perfusion; mucous membranes, bowel sounds, liver evaluation; urinalysis, LFTs, renal function tests, CBC and differential Interventions WARNING: Alert surgeon:Note use of benazepril onpatient's chart; theangiotensin II formationsubsequ ent tocompensatory reninrelease during surgery willbe blocked; hypotensionmay

Generic name: Benazeprilhydrochloride Brand Name: Lotensin Pregnancy Category C (first trimester)Pregnancy Category D(second and third trimesters)

Benazepril and its metabolite benazeprilat inhibit ACE that catalyzes the conversion of angiotensin I to angiotensin II, thus leading to reduce daldosterone secretion by the adrenal cortex and decreased vasopressor activity.

Hypersensitivity. History of bilateral renal artery stenosis, angioedema; pregnancy

Headache, dizziness, fatigue ; cough; somnolence, nausea; hypotension, transient elevations in BUN and serum creatinine; palpitations; constipation ,gastritis; melena,rash, pruritus; musculoskeletal pain; paraesthesia, anxiety; UTI; hyperkalaemia; leucopeniaand flushing. PotentiallyFatal: Angioedema(rare)

Treatment of hypertension alone or in combination with thiazide-type diuretics

Classification: Antihypertensive ACE inhibitor DOSAGE: Oral Hypertension Adult: Initially, 10 mg oncedaily. Maintenance: 20-40mg daily as a single or in 2divided doses. Max dose: 80mg/day. Child: 6 yr: 0.2 mg/kg/day.Max dose: 40 mg/day. Renal impairment: Avoidusage in children with CrCl<30 ml/min.

be reversed withvolume expansion. Monitor patient for possibledrop in BP secondary toreduction in fluid volume(excessive perspiration anddehydration, vomiting,diarrhea) becauseexcessiv e hypotension mayoccur.

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