New Brunswick Scientific
Where Quality and Innovation Have Become Tradition
2.5L - 14.0L BIOFLO 310 FERMENTATION SYSTEM
The Ultimate Benchtop Fermentor for Research through Production
The BioFlo 310 Fermentor Advanced Control in a Compact Package.
New Brunswick Scientific's BioFlo 310 benchtop fermentor has been improved to provide you with even greater flexibility. Now, this powerful benchtop system can be used for growth of virtually any bacteria, yeast, or fungi, and can be adapted for mammalian, insect or plant cultures with the use of optional accessories. With the power to regulate up to 32 parameters each, and one to four vessels simultaneously, (128 parameters total), it's virtually impossible to outgrow its control capabilities. This advanced system allows you to easily connect and control your existing analyzers, pumps, sensors and other ancillary devices. A user-friendly touchscreen controller integrates it all, simplifying setup, calibration & operation.
Powerful Fermentor Has it All
Compact design maximizes bench space. cGMP-compliant to meet your requirements in research through production. Batch, fed-batch & continuous modes for growing a wide variety of cell types. Fully-integrated system is ready for out-of-the box startup. Includes a Master Control Station with built-in controller, touchscreen monitor, pumps and thermal mass flow controller with 4-gas control. Vessel, pH/DO/and level/foam probes, hoses, sterile sampler & more are included.
Our new headplate design provides added flexibility so you can insert your probes, sampling tube, and exhaust gas condenser wherever you choose.
Advanced Touchscreen Controller Simplifies Operation
Large 15" touchscreen clearly displays all setpoints, current values, cascade
loops and more. Display screens are straightforward and easy to navigate. Integrate up to ten of your sensors, scales, analyzers or other external devices for optimized process control. User-customizable trend graphs make it easy to track and export data. Trends up to 8 loops simultaneously. Built in flexibility to customize all your PI values, or select factory defaults. Save up to 10 of your recipes per fermentor for repeat usage.
Stainless-steel, hemispherical base with built-in heat exchanger for circulation of warm or cool water provide superior temperature control and rapid transfer of heat for temperature inductions. Thick-walled glass vessel resists rough handling and repeated autoclaving. Easily de-couples without tools for cleaning.
Available in Four Sizes With Multiple Options.
Interchangeable, autoclavable glass vessels are available in four sizes. 2.5, 5.0,
7.5 and 14.0 liters, total volume. Pre-configured packages simplify ordering. Customize by selecting from our wide range of options. Add multiple mass flow controllers, Redox or second pH and second DO probes, BioCommand supervisory software & more. Validation & training packages are available.
Multiple connections are provided for integrating ancillary equipment, a second touchscreen display & BioCommand supervisory software. USB ports for exporting trend data and importing firmware upgrades are also provided. All are easily accessed from the rear of the unit. Packed with power, to regulate one to four fermentors from a single controller!
New Brunswick Scientific
Where Quality and Innovation Have Become Tradition
Standard Pre-Configured Packages include a Master Control Station with vessel and probes to simplify ordering Each Master Control Station includes a controller & touchscreen monitor interface capable of running one to four fermentors Cost-Saving Utility Stations for running optional 2nd, 3rd & 4th fermentor(s) do not include controller & touchscreen interface
Adjustable-Angle, User-Friendly 15" Touchscreen Interface controls one to four fermentors simultaneously
New synoptic screen provides pictorial alternative to the summary screen for viewing & editing process values
Customize PI Values for All Process Parameters or select factory defaults
A Thermal Mass Flow Controller (TMFC) with 4gas control is built into each Master Control Station and Utility Station to precisely control total gas flow rate. Additional TMFCs for individual gas control and gas overlay can be added Connections for Gasses & Vessel Components are easily accessible Quick Connects allow utilities to be added in seconds
pH, DO and Level/Foam Probes are provided. Options are available for Redox or 2nd pH probe, and 2nd DO probe
On-Off Switch is front mounted
for easy access
Three Assignable Pumps are
standard. Built-in controls and connections are provided for additional pumps. View total pump flow rate & easily calibrate pumps via touchscreen
Unique Heat Exchanger
Four baffles ensure thorough mixing
enables rapid temperature removal after autoclaving & from exothermic cultures; and rapid rises for heat inductions
Summary Screen lets you conveniently view setpoints, current values, cascade loops and more for up to 10 parameters simultaneously. All 32 parameters can be viewed simply by scrolling up or down.
Trend graph screen makes it simple to track & export data on up to eight process variables over a six day span. Customize the view by selecting the parameters, colors & interval between sample measurements.
The setup screen lets you easily configure your settings assign pumps, change vessel size for more accurate PI values, save up to 10 recipes, add additional fermentors, and more.
BioFlo 310 Fermentor Specifications*
VESSEL VOLUME HEADPLATE PORTS VESSEL DIMENSIONS for Autoclave VESSEL DIMENSIONS with Slant Rack CONTROLLER Total Capacity Working Volume Size Height w/ Cond. /Filter Without Cond. /Filter Diameter Height Diameter 2.5 Liters 0.75 - 1.75 Liters (1) 6.35 mm (9) PG 13.5 21 16.5 8 11 11 53 cm 42 cm 20 cm 28 cm 28 cm 5.0 Liters 7.5 Liters 14.0 Liters 1.25 - 3.75 Liters 2.0 - 5.5 Liters 3.0 - 10.5 Liters (3) 6.35 & (1) 19 mm (3) 6.35 & (1) 19 mm (3) 6.35 & (1) 19 mm (10) PG 13.5 (12) PG 13.5 (12) PG 13.5 24 18.5 10 13 11 61 cm 47 cm 25 cm 34 cm 28 cm 25.5 20 11 16 11 65 cm 51 cm 28 cm 41 cm 28 cm 28 23.5 12 18 12 71 cm 60 cm 31 cm 46 cm 31 cm
NBS SALES OFFICES
USA HEADQUARTERS 800-631-5417 732-287-1200 Fax: 732-287-4222
[email protected] www.nbsc.com PO Box 4005 44 Talmadge Rd. Edison, NJ 08818-4005 UNITED KINGDOM
Controls 1 to 4 vessels, 32 control loops per vessel. Stores 10 recipes & 8 process variables for Master Control Station trend graphing, per vessel. Includes an industrial touchscreen monitor/ user interface, 3 built-in pumps, and connections for all utilities & communications signals used by the first fermentor One each required for optional 2nd, 3rd or 4th fermentors. Each includes 3 built-in pumps & connecUtility Station tions for all utilities & communications signals. Built with 7 analog inputs & 7 analog outputs Touchscreen Interface/Display 15" Industrial touchscreen interface / display, capable of supporting up to four fermentors, is standard with a Master Control Station. Optional second touchscreen is available and replicates the image shown on the first display Digital display in 0.1C increments via Platinum RTD probe From 5C above coolant temperature to 80C via PID control. (Minimum 4C.) Permanent magnet motor with high torque input Digital display in 1 RPM increments 50 - 1,200 RPM via PID control Two six-bladed Rushton impellers standard. Other options available Four 316L removable, stainless steel baffles 350 mM O2/L/Hr or more Stainless-steel exhaust condenser, mounted on the headplate. Uses 0.2 disposable filter Standard: 1 Thermal Mass Flow Controller (TMFC) with four-gas control (4 solenoid valves) Optional: Rotameter or multiple TMFCs for individual gas control Ring sparger is provided with 0.2 disposable filter One gel pH probe with digital display in 0.01 increments. 2nd probe optional 2 - 14 pH, via PID control. Cascade to pumps, gases and external loops One Polaragraphic DO probe with digital display in 0.1% increments. 2nd probe optional 0 - 200%, via PID control. Cascade to agitation, gases, pumps and external loops One Foam/Level sensor. (Two additional foam/level sensors can be added) Redox or 2nd pH probe & 2nd DO probe are available. (External sensors can be added) 3 Built-in, assignable, peristaltic pumps are standard. External pumps can be added. Control modes: Off, Prime, Base, Acid, Foam, Level 2 Wet, Level 2 Dry, Level 3 Wet or Level 3 Dry Pumps 1 & 2: Pump 3: 12 RPM Fixed speed duty cycle ability to view total pump flow rates 100 RPM Fixed speed duty cycle ability to view total pump flow rates Gas: 10 PSIG maximum
TEMPERATURE
Indication & Sensor Range & Control Drive Indication Range & Control Impellers Baffles
0800 581331 +44 (0) 1727 853855 Fax: +44 (0) 1727 835666 [email protected]
17 Alban Park, Hatfield Rd St. Albans, AL4 0JJ THE NETHERLANDS + 31 (0)24 3717 600 Fax: + 31 (0)24 3717 640 [email protected] Kerkenbos 1101, 6546 BC Nijmegen P.O. Box 6826, 6503 GH Nijmegen FRANCE + 33 (0)1 53 53 15 11 Fax: + 33 (0)1 53 53 15 57 [email protected] 12 - 14, Rond Point des Champs Elyses 75008 Paris BELGIUM +32 (0) 16 562 831 Fax: +32 (0) 16 572 753 [email protected] Stationsstraat 180/4 B-3110 Rotselaar Belgi/Belgique
AGITATION
OXYGEN TRANSFER RATE (OTR) EXHAUST AERATION Condenser & Filter Gas System Gas Inlet pH DO Sensor Range & Control Sensor Range & Control Foam/Level OTHER SENSORS PUMPS Optional Sensors Standard, Options & Control Speed UTILITIES ELECTRIC NET WEIGHT DIMENSIONS
wide x deep x high
Water & Gas Service Control Station Utility Station External Devices 2 USB Ports **
Water: 10 PSIG maximum, 50 filtration.
GERMANY +49 (0)7022-932490 Fax: +49 (0)7022-32486 88 lbs. [40 kg], including 15 lb. [6.8 kg] touchscreen [email protected] With Touchscreen: 25" x 24" x 34" (63.5 x 61 x 86 cm). Without: 18" x 24" x 28" (46 x 61 x 71 cm) In der Au 14 D-72622 Nrtingen
100 - 120 V 50/60 Hz & 208 - 230 V 50/60 Hz. All are single phase, and draw 15 Amps
INPUT / OUTPUT CONNECTIONS & COMM PORTS (Built into the
back panel of Master Control & Utility Stations )
Seven analog inputs & seven analog outputs for your external devices such as analyzers, sensors, external pumps, etc. (Reduce by 1 input & output for each additional TMFC added) Import firmware/software upgrades and export trend data. Connect optional 8-port serial box for scales, etc. (USB Ports built into Master Control Station only) For optional second touchscreen display Optional for Redox or second pH probe, and a second DO probe CAN/CSA-C22.2 Nos. 1010.1 & 1010.2.010 UL Standard UL-61010A-1 & 61010A-2-010
Communications Port For optional BioCommand/SCADA software Auxiliary Monitor Secondary Probes
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CHINA +86-21-648 45955 Fax: +86-21-648 45933 [email protected] A903, 904 Yin Hai Bldg., No. 250, Cao Xi Rd. Shanghai 200235
REGULATORY COMPLIANCE
Specifications are subject to change without notice. As shown, for operation as a fermentor. Optional vessels & impellers, agitation and gas control options enable use as a cell culture system. Capable of 1C/minute temperature rises in vessels up to 7.5L. Ambient operating conditions of 10 to 30C, up to USB Ports built into Master Control Station only. 80% relative humidity, non-condensing.
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B4020a
10IG_1_2007
New Brunswick Scientific Co., Inc.
